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VKRAKVQQITPHDLRHTAASLAVSAGVNVLALQRILGHKSAKVTLDTYADLFDADLDAVAVTLGKDADQQ T
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv3751 | - | - | 100% (71) | PROBABLE INTEGRASE (FRAGMENT) |
| M. tuberculosis H37Rv | Rv2309c | - | 4e-12 | 50.85% (59) | hypothetical protein Rv2309c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3777 | - | 8e-35 | 100.00% (71) | putative integrase (fragment) |
| M. gilvum PYR-GCK | Mflv_4644 | - | 5e-08 | 50.00% (50) | phage integrase family protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_4848 | - | 8e-10 | 40.00% (65) | prophage integrase |
| M. avium 104 | MAV_2266 | - | 2e-07 | 55.56% (45) | phage-related integrase |
| M. smegmatis MC2 155 | - | - | - | - | - |
| M. thermoresistible (build 8) | TH_3747 | - | 8e-06 | 43.10% (58) | PUTATIVE phage integrase family protein |
| M. ulcerans Agy99 | MUL_0529 | - | 2e-09 | 41.27% (63) | prophage integrase |
| M. vanbaalenii PYR-1 | Mvan_1114 | - | 3e-08 | 50.98% (51) | phage integrase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Rv3751|M.tuberculosis_H37Rv --------------------------------------------------
Mb3777|M.bovis_AF2122/97 --------------------------------------------------
MMAR_4848|M.marinum_M --------------------------------------------------
MUL_0529|M.ulcerans_Agy99 --------------------------------------------------
MAV_2266|M.avium_104 --------------------------------------------------
Mflv_4644|M.gilvum_PYR-GCK -MLPEHDYAPTPETPAQIYAAYLVHLQRRDRGNTAYAQ---AARSFLRRW
Mvan_1114|M.vanbaalenii_PYR-1 -MPPVLAYVPAPD--ADLLTDYDAHCTRLGLTSRNLRS---AARTFLRCW
TH_3747|M.thermoresistible__bu MTTPALAMVDPLADPDTVLADYLEYVAALGLSGRSVRARTLIATTFLTSH
Rv3751|M.tuberculosis_H37Rv --------------------------------------------------
Mb3777|M.bovis_AF2122/97 --------------------------------------------------
MMAR_4848|M.marinum_M --------------------------------------------------
MUL_0529|M.ulcerans_Agy99 --------------------------------------------------
MAV_2266|M.avium_104 --------------------------------------------------
Mflv_4644|M.gilvum_PYR-GCK PRVQSWADIPLDEQLAANCST--RPFVTFLMVSRRLQPGYDYLVHRKLSS
Mvan_1114|M.vanbaalenii_PYR-1 PDPQQWAGEPLQTRLSASHTT--RCFVTFLMLAGHLRPGYDYLICRKLSV
TH_3747|M.thermoresistible__bu PDLRDWMTRPAAERLIELRRTGAWPLLCHLIGRGELRLDLELAAVKNLTG
Rv3751|M.tuberculosis_H37Rv --------------------------------------------------
Mb3777|M.bovis_AF2122/97 --------------------------------------------------
MMAR_4848|M.marinum_M -----------------MAGSVPRGIRKRTNSAGQARYQVRYLVRDPNSP
MUL_0529|M.ulcerans_Agy99 -----------------MAGNTPRGIRKRLNAAGEPRYQVRYLIRDPDAP
MAV_2266|M.avium_104 ---------------MTQKRNLRAGVEDRWNKTVRDEHGNPQTVPSATYG
Mflv_4644|M.gilvum_PYR-GCK LWHELTDSCLQPDLDQFISAALELGFTERVASAIGSQIIARLLIQTGRPL
Mvan_1114|M.vanbaalenii_PYR-1 FWRHMPPGLLAQDLARFLGAAEELGFTERTRSASASQVIGRLLIQTGRRL
TH_3747|M.thermoresistible__bu LGRAVED-RDPDGFAAVRAAGLALGWTPQWIETVLGECLAVLLAWHGGLV
Rv3751|M.tuberculosis_H37Rv --------------------------------------------------
Mb3777|M.bovis_AF2122/97 --------------------------------------------------
MMAR_4848|M.marinum_M SG----------WVETSSTFATMREARAFKADRDGEAAIG--------AR
MUL_0529|M.ulcerans_Agy99 SG----------WVETSATFPTLREAKAFKSERDNEAALG--------AR
MAV_2266|M.avium_104 KGKR--------WRARYVDEQGREHVQSFTRKVDAQQWLTNQTATIVAGT
Mflv_4644|M.gilvum_PYR-GCK TGLRESDLQELLHACHVRQERTGRGAKHYRSTTHSARQILFHLGILDTQA
Mvan_1114|M.vanbaalenii_PYR-1 DALTNNDFDDLLAASAARRG-ADKPSRHYSSGAHTARQVMFHLGVFTDQP
TH_3747|M.thermoresistible__bu SGVSADTVDEFDAALAATQSIPATSRRAYRNRIAGLRQMLFQARIVDTPP
Rv3751|M.tuberculosis_H37Rv --------------------------------------------------
Mb3777|M.bovis_AF2122/97 --------------------------------------------------
MMAR_4848|M.marinum_M RFDPRLG-----------------RASLSAIWTQYSASKQPAVSPKTWSG
MUL_0529|M.ulcerans_Agy99 RFDPRLG-----------------RTPLSRIWTQFSDSKKPAVSPKTWSG
MAV_2266|M.avium_104 HVAPRDA-----------------KLTVQQWCDTWIEGYKVHREGTVR--
Mflv_4644|M.gilvum_PYR-GCK RPAVTAL--TLEQRMVDVPVA--LRPAFVAYLNRKYATCVPKTVSSLATR
Mvan_1114|M.vanbaalenii_PYR-1 VNATSLLRQSFAQRMRDASPS--LRGSFVAYLDRLTATHSRGTVAGTATR
TH_3747|M.thermoresistible__bu RRRRWAR--SYAQRFAEVPMADAIRATLLRYVTVRASVLRPKSVESLIND
Rv3751|M.tuberculosis_H37Rv --------------------------------------------------
Mb3777|M.bovis_AF2122/97 --------------------------------------------------
MMAR_4848|M.marinum_M YAQHWELRISPRFGHVPVDEISRK-DVQQFIGGLTVG-------------
MUL_0529|M.ulcerans_Agy99 YNQHWELRIKPRFGHVPVDEITRA-DVRAFVDGLTVG-------------
MAV_2266|M.avium_104 EARTHIRQIVTEFGDTPLTQVRPS-QVKAWTARLRADGM-----------
Mflv_4644|M.gilvum_PYR-GCK LAHFGRYLAAADPSLTSLNQLDRRRHIEPFITSLTTATN------SVTGE
Mvan_1114|M.vanbaalenii_PYR-1 LNHFAAHLYAVDPTLTTLANLDRRRHIETYLTATAEATN------SRTGA
TH_3747|M.thermoresistible__bu LLPFADYLTTAHPEVTSLEDLDRN-HIEGFLVWNRTRTWRGQRAASGAGR
Rv3751|M.tuberculosis_H37Rv --------------------------------------------------
Mb3777|M.bovis_AF2122/97 --------------------------------------------------
MMAR_4848|M.marinum_M ---PWAKLATLRLLRSILDMAREDGRIHINPAQGVSSGRIPARERHR---
MUL_0529|M.ulcerans_Agy99 ---PWAKVSTLRLLRSILDVAHQDGRIHRNPALGVSAGRIPERERHR---
MAV_2266|M.avium_104 --KASYIYALHSRLSQIMADAVHDGVLGRNPCSRRTAPPMG-KAKVY---
Mflv_4644|M.gilvum_PYR-GCK PITVADRIRCIHAVGNFLAEITEWGWDDAPPRRLIFRTDLPRPPRCLPRY
Mvan_1114|M.vanbaalenii_PYR-1 PIQASERRGRVLAVHCFLNDIAEWGWPEAPPRRLVFRSDIPKLPRALPRY
TH_3747|M.thermoresistible__bu IISKAVIQSTVLSVRNLLDDITEWGWEQAPPRRLVFAVDVPKLDQPLPRA
Rv3751|M.tuberculosis_H37Rv --------------------------------------------------
Mb3777|M.bovis_AF2122/97 --------------------------------------------------
MMAR_4848|M.marinum_M ---YLSATEVAALAHACGDQGDIVTIL-AFTGLRWSELVGLRVGDIDLKA
MUL_0529|M.ulcerans_Agy99 ---YLTAQEVRMLATACGDQGDVVTIL-AYTGLRWSEPVGLRVKDIDLTA
MAV_2266|M.avium_104 ---VATTEQVWALHDAVPDHLKVAVLLGAFAGLRVAEVSGLRVSDVDFIR
Mflv_4644|M.gilvum_PYR-GCK LPVDSDRKLTAALAKSPYRLAADALLVQRACGLRIGELLDLELDCIHEIP
Mvan_1114|M.vanbaalenii_PYR-1 LTPDLDRRLTQALQAWPDRLPADALLLQRATGLRIGELVELELDSVHEIP
TH_3747|M.thermoresistible__bu LPPDIDVAVMNAVSGLDDSFARIGLTVLRGAGLRVGELLDLELGSVIDYG
Rv3751|M.tuberculosis_H37Rv --------------------------------------------------
Mb3777|M.bovis_AF2122/97 --------------------------------------------------
MMAR_4848|M.marinum_M RRLYVRQAAPDVEGRIIVGPPKTRAAVRTVPLPRIVIDALKPRIENRSTK
MUL_0529|M.ulcerans_Agy99 RRLYVRRAAPEVEGHIVIGPPKTRAGIRTVPLPQVVVDIFKGRITGQAPD
MAV_2266|M.avium_104 GVVHPKQQWSD-------KPLKTEGSSAPIPIPQDLALLLSASVQKYPAE
Mflv_4644|M.gilvum_PYR-GCK GQGSWLKVPLGKLNSERMIPVDDEVLTLVDRITTTRSSGRPMIHPRTGAP
Mvan_1114|M.vanbaalenii_PYR-1 GQGAWLKVPLGKLNTERMVPLDDDTVALIDRIVAHRSLGRPLPHPRTARP
TH_3747|M.thermoresistible__bu PAGTWLKVPLGKLATERMVPLSVATIAALDEWTTGRGICRPLPHPRTGAL
Rv3751|M.tuberculosis_H37Rv --------------------------MKRAK-----VQQITPHDLRHTAA
Mb3777|M.bovis_AF2122/97 --------------------------MKRAK-----VQQITPHDLRHTAA
MMAR_4848|M.marinum_M EQAITSPNGGFLRSNNWRRHTHWNKALKKTG-----LAPLTIHDLRHTYA
MUL_0529|M.ulcerans_Agy99 QPAVTSTNGAMLRSNNWRRHTHWNKALKSTD-----LAPLTIHDLRHTYA
MAV_2266|M.avium_104 MMVTNGLGTDRCGPWIIERAIRDVRRGIDGL-----PEGFSFHDLRHYLA
Mflv_4644|M.gilvum_PYR-GCK ADFLFTHHGKRLSQNAVREELNRAAQAASLG-------HITPHQLRHTYA
Mvan_1114|M.vanbaalenii_PYR-1 TDYLFTHHGRRLTVDHIRDVLGRVTTDANLP-------HITPHQLRHTYA
TH_3747|M.thermoresistible__bu TDFLFVAHGRRLSQTRLRNGLIAAVETCGLRGAGGAPLVVTPHQLRHTWA
.: *:*** *
Rv3751|M.tuberculosis_H37Rv SLAVSAGVNVLALQRILGHKSAKVTLD-------TYADLFDADLDAVAVT
Mb3777|M.bovis_AF2122/97 SLAVSAGVNVLALQRILGHKSAKVTLD-------TYADLFDADLDAVAVT
MMAR_4848|M.marinum_M SLARKSGADLRYVQKTMGHSTPTVTAN-------IYSDLYSDELDHVATN
MUL_0529|M.ulcerans_Agy99 SLARKSGADLRYVQKTMGHSTPTVTAN-------IYSDLYADELDQVATN
MAV_2266|M.avium_104 SLLIARGCDVKTVQARLRHSSAKTTLD-------TYSHLWPDADESTRSA
Mflv_4644|M.gilvum_PYR-GCK TALINAGVSLQALMALLGHVSTQMSLRYAHLFDHTVRTEYERALDLAKSH
Mvan_1114|M.vanbaalenii_PYR-1 TALVNAGVSLQSLMALLGHVSAEMSLRYGRLFDATVRTEYERALTAAKAH
TH_3747|M.thermoresistible__bu TELANAGMGLQALMALLGHVTPQMTLRYATLASPTLRDAYDQAMGKMRRR
: * .: : : * :. : :
Rv3751|M.tuberculosis_H37Rv L-------------------------------------------------
Mb3777|M.bovis_AF2122/97 L-------------------------------------------------
MMAR_4848|M.marinum_M LD------------------------------------------------
MUL_0529|M.ulcerans_Agy99 LD------------------------------------------------
MAV_2266|M.avium_104 IG------------------------------------------------
Mflv_4644|M.gilvum_PYR-GCK IGALPK-TAVGLPITDITGTGWKDTPAIKSRLAGGYCLRAPAQGSCPYAN
Mvan_1114|M.vanbaalenii_PYR-1 LGTLPTGPPQGRISLPIVDGDWKDAPAIKARLAGGFCIRAQVQGPCAYAN
TH_3747|M.thermoresistible__bu F----TLTPVGKPIVP-DAVIWLGSEMLKTRVAHGYCSRHESAGACPYAN
:
Rv3751|M.tuberculosis_H37Rv ----------------------------GKDADQQT--------------
Mb3777|M.bovis_AF2122/97 ----------------------------GKDADQQT--------------
MMAR_4848|M.marinum_M ----------------RLNDVAKDQAN-GQEPDTPKHP------------
MUL_0529|M.ulcerans_Agy99 ----------------QLHATEIQTPTTGQEPDEPNQPSSA---------
MAV_2266|M.avium_104 ----------------AVLAERVDSGETTADELRTMRPGRGRRRRSGV--
Mflv_4644|M.gilvum_PYR-GCK ICEHCPSFHTDSTHLAVLAAQRIDAQDLAADAEKRGWIDEAERHHNLVSR
Mvan_1114|M.vanbaalenii_PYR-1 ICEHCPNFRTDTGYLPVLAAQRADTETLARDAEARGWTEEAERHRRLIAR
TH_3747|M.thermoresistible__bu ICETCDNFVTGPEFRDALEAQRTDVEALEVDARDRGWPDEAARHHRVADA
:
Rv3751|M.tuberculosis_H37Rv -----------
Mb3777|M.bovis_AF2122/97 -----------
MMAR_4848|M.marinum_M -----------
MUL_0529|M.ulcerans_Agy99 -----------
MAV_2266|M.avium_104 -----------
Mflv_4644|M.gilvum_PYR-GCK LDALITGSASA
Mvan_1114|M.vanbaalenii_PYR-1 LDAHISQTQTG
TH_3747|M.thermoresistible__bu LTDHLQRLDR-