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MPATLSQIQAWSTEHLIDAAAYWTQTADRWEDAFLTMRNQAQSITWHGAGGDALRQRTGADVSVVSGKAD QLRQAAGIARNGASEISAAQRRVLYGVEDAQNAGFTVGEDLSVTDTRSTSPAERAARQAQAEAFAADLRL RAEQLEAADTKAAGQITATAGDVGNATFTPAHNGNGVQLVDFKQDGGPVCDDPDYNDRFFRKFMGRVGAG AAIGGLAGAPEAGVGAIPGAIIGGAAGGIEAFIEGATESEPPKCGK
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_0692 | - | - | 100% (256) | hypothetical protein MAV_0692 |
| M. avium 104 | MAV_1479 | - | 3e-84 | 76.70% (206) | hypothetical protein MAV_1479 |
| M. avium 104 | MAV_2254 | - | 7e-83 | 70.93% (227) | hypothetical protein MAV_2254 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2102c | - | 3e-67 | 66.84% (196) | transmembrane protein |
| M. gilvum PYR-GCK | Mflv_1972 | - | 1e-24 | 37.43% (187) | hypothetical protein Mflv_1972 |
| M. tuberculosis H37Rv | Rv2077c | - | 3e-67 | 66.84% (196) | transmembrane protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0016 | - | 6e-16 | 29.63% (162) | hypothetical protein MAB_0016 |
| M. marinum M | MMAR_0116 | - | 4e-71 | 68.02% (197) | hypothetical protein MMAR_0116 |
| M. smegmatis MC2 155 | MSMEG_5600 | - | 1e-22 | 34.88% (172) | hypothetical protein MSMEG_5600 |
| M. thermoresistible (build 8) | TH_3926 | - | 2e-23 | 33.07% (251) | PUTATIVE putative hypothetical protein Mvan_5711 |
| M. ulcerans Agy99 | MUL_1136 | - | 5e-51 | 63.06% (157) | hypothetical protein MUL_1136 |
| M. vanbaalenii PYR-1 | Mvan_5711 | - | 9e-22 | 30.89% (246) | hypothetical protein Mvan_5711 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2102c|M.bovis_AF2122/97 -----------MLATLSQIRAWSTEHLIDAAGYWTETADRWEDVFLQMRN
Rv2077c|M.tuberculosis_H37Rv -----------MLATLSQIRAWSTEHLIDAAGYWTETADRWEDVFLQMRN
MAV_0692|M.avium_104 -----------MPATLSQIQAWSTEHLIDAAAYWTQTADRWEDAFLTMRN
MMAR_0116|M.marinum_M -----------MPATLSQVRAWSTEHLIDTAGYWTKTADQWENAFFQMRN
MUL_1136|M.ulcerans_Agy99 -----------MVLTLSQVQAWRTEHLIEAATYWSKTADQWEDVFLQMRN
Mflv_1972|M.gilvum_PYR-GCK ------------MPSRSEVESWETADLDAAASRWRTAGDVLESAFEQHRQ
MSMEG_5600|M.smegmatis_MC2_155 MSPTATPAEGGEGLSRSRIESWDTTHLENATARWRATATELEGHFEQLRQ
TH_3926|M.thermoresistible__bu ---MIDALPASGLPTLSQIQGWQTAHLRSAARRWRVTADTWTSIYDDIAA
Mvan_5711|M.vanbaalenii_PYR-1 -----MSVVAHGLPTLSQIENWETAHLACAARRWTAAAEHWESSFGLIAD
MAB_0016|M.abscessus_ATCC_1997 ------------MPTKSEILNWRTDHLGAAAKTWGDQATQLDTAVNGAQG
: *.: * * .* :: * .
Mb2102c|M.bovis_AF2122/97 ---QAHAIAWNGAGGDGLRQRTRADFSTVSGIADQLRRAATIARNGAGTI
Rv2077c|M.tuberculosis_H37Rv ---QAHAIAWNGAGGDGLRQRTRADFSTVSGIADQLRRAATIARNGAGTI
MAV_0692|M.avium_104 ---QAQSITWHGAGGDALRQRTGADVSVVSGKADQLRQAAGIARNGASEI
MMAR_0116|M.marinum_M ---QSYALGWSGAGGDALRERTSADLPIVGAKADMLRQAAGIAGNGASDI
MUL_1136|M.ulcerans_Agy99 ---QSHTLVWEGAGGDALRQRTGADLAIVSTKADELRQASKIARDGAGTI
Mflv_1972|M.gilvum_PYR-GCK NILTPGGTAWEGDAKDAALDRVTADTSVVRRQGDVHRVAADIAARGSEDI
MSMEG_5600|M.smegmatis_MC2_155 HVLAPGGTEWEGDAKDAALERATQNLNTVRAAGDIARSAADLAENSSADI
TH_3926|M.thermoresistible__bu DLSAKSEIVWEGDASTAAQARTKRDRDTVELLAERLYFGASIAESGAAMV
Mvan_5711|M.vanbaalenii_PYR-1 GVRSPHGTQWEGAAQAAAQARADSDLAGVRMLADRLRTAARTAVDGGSAI
MAB_0016|M.abscessus_ATCC_1997 ---LLDGLRGSGQFVEAFRTRLKSYIDKTRPKVDKLKSAKQVAESSEQQL
* . * . : . * . :
Mb2102c|M.bovis_AF2122/97 DAAQRRVMYAVEDAQDAGFNVGEDLSVTDTKTTQPAAVQAARLAQAQALA
Rv2077c|M.tuberculosis_H37Rv DAAQRRVMYAVEDAQDAGFNVGEDLSVTDTKTTQPAAVQAARLAQAQALA
MAV_0692|M.avium_104 SAAQRRVLYGVEDAQNAGFTVGEDLSVTDTRSTSP-AERAARQAQAEAFA
MMAR_0116|M.marinum_M SAAQRRVLYAVEDAHNAGFTVGEDLSVTDTHRSGTPAEQAARQAQAQAFA
MUL_1136|M.ulcerans_Agy99 GIAQRRVLHAVEDAHNAGFTVGEDFSVTDIRTSRRSAEQAARQAQAQAQA
Mflv_1972|M.gilvum_PYR-GCK QGARSRVLEAIAEAEQDDFTVGEDLSVTDNR-AYDLETAAARMTAATEHA
MSMEG_5600|M.smegmatis_MC2_155 SAAKRDALQSISDAEADGFEVNEDLSVRDTS-RVDVSTMAARYTAAREHA
TH_3926|M.thermoresistible__bu DQAKEEALLVVRVAGALAFDVREDLSLVDRLATGSPAATAVRLQQSNVLA
Mvan_5711|M.vanbaalenii_PYR-1 EAAKHEALTVIAATNAMGFEVADDLTVWNRMG------AALRRNDAELLG
MAB_0016|M.abscessus_ATCC_1997 KGAKDKAVYAVHDPEDEDFNVNEDLSVTERR-SHSGLDRLKRAIRRRWLQ
*: .: : . * * :*::: : *
Mb2102c|M.bovis_AF2122/97 GDIRLRVGQLVAAENEVSGQLAATT-GDVGNVRFAG--------------
Rv2077c|M.tuberculosis_H37Rv GDIRLRVGQLVAAENEVSGQLAATT-GDVGNVRFAG--------------
MAV_0692|M.avium_104 ADLRLRAEQLEAADTKAAGQITATA-GDVGNATFT---------------
MMAR_0116|M.marinum_M GDIRLHARQLDGADAKVAGQLTAAT-ADLSSVGFAQNPIP----------
MUL_1136|M.ulcerans_Agy99 QATDIRQRAVEPVPPPAPGRLPPLTPGEMATPRLPAPP------------
Mflv_1972|M.gilvum_PYR-GCK EFIRWRVEQLVATDALIGQQLQANA-AELEGIRFEGDRDGNGTDPTIRLV
MSMEG_5600|M.smegmatis_MC2_155 ENIQWNANQLLATDTLIGRRLTAKA-AELNGVRFDDEPEG----------
TH_3926|M.thermoresistible__bu ATVRVGAAQLVSTDHAVAQRLREAT-DDFDSFDFARNP------------
Mvan_5711|M.vanbaalenii_PYR-1 ISVRTGAAQLAAVDHAVATELDSVT-AGFDALNIGEGP------------
MAB_0016|M.abscessus_ATCC_1997 GILHTRAQELVATDNAIARKLHEIA-QDLSNFHLEGPDGNTDFSGDPNHP
: . .: : . :
Mb2102c|M.bovis_AF2122/97 -------------------------------------APVVAHSAVQLVD
Rv2077c|M.tuberculosis_H37Rv -------------------------------------APVVAHSAVQLVD
MAV_0692|M.avium_104 --------------------------------------PAHNGNGVQLVD
MMAR_0116|M.marinum_M ----------------------------------ATQAPTTHRNGVQLVD
MUL_1136|M.ulcerans_Agy99 -------------------------------------PQPPIRGGADLAP
Mflv_1972|M.gilvum_PYR-GCK DNKTEDKGSQAESSEQRGAGSLSEESTGTWQDMLAPEESAESAEGADTAE
MSMEG_5600|M.smegmatis_MC2_155 -------------------------------------TIRAASFGDGFKQ
TH_3926|M.thermoresistible__bu -------------------------------------IIQPLSTDSDEHH
Mvan_5711|M.vanbaalenii_PYR-1 -------------------------------------VIAPIAAGDDGQS
MAB_0016|M.abscessus_ATCC_1997 KIMG-----------------------------PAKPLGPIEQEDYDLGY
Mb2102c|M.bovis_AF2122/97 FFKQDGPTPPPPGAPHPSGGADGPYSDPITSMMLPPAGTEA---------
Rv2077c|M.tuberculosis_H37Rv FFKQDGPTPPPPGAPHPSGGADGPYSDPITSMMLPPAGTEA---------
MAV_0692|M.avium_104 -FKQDG----------------GPVCD-----------------------
MMAR_0116|M.marinum_M -FKQNGGEPPPFAPWDTPDGTPPPGAPGLSPELQQMILGGD---------
MUL_1136|M.ulcerans_Agy99 ----------------------AEPPPVVRTPMEPPARLG----------
Mflv_1972|M.gilvum_PYR-GCK SPLEALLGEGETAEGQQRSSLDEALTEVAGKPVDAPPTALERILSQHTGT
MSMEG_5600|M.smegmatis_MC2_155 SPFDDLLT-----KEQALAAWEKLQTDIASYNSRCAVNIVG---------
TH_3926|M.thermoresistible__bu ----------------FGTCFAESFKEDVGKNMVQGVFVGG---------
Mvan_5711|M.vanbaalenii_PYR-1 ----------------FGQCFADRFKDDIGENMVQGVFVGG---------
MAB_0016|M.abscessus_ATCC_1997 TFLDENGNPLPMLDENGNVVIDPKTGRPVPDSVWGDPADNN---------
Mb2102c|M.bovis_AF2122/97 -----------PVSDATKRWVDNMVNELAARPPDDP---------IAVEA
Rv2077c|M.tuberculosis_H37Rv -----------PVSDATKRWVDNMVNELAARPPDDP---------IAVEA
MAV_0692|M.avium_104 ------------DPDYNDRFFRKFMGRVGAG-------------------
MMAR_0116|M.marinum_M -----------PANLTGQGLLDNLQQLVQSLPENDPRTAWLRGQVADLQA
MUL_1136|M.ulcerans_Agy99 --------------------------------------------------
Mflv_1972|M.gilvum_PYR-GCK GRGEDRRYTQHPLEAPIVGADSSVIGDQQARVDAAHESVESAQGALDDAL
MSMEG_5600|M.smegmatis_MC2_155 -----------PLPPPQYAACQQELAFLQG----------------QEAA
TH_3926|M.thermoresistible__bu --------------------------------------------------
Mvan_5711|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_0016|M.abscessus_ATCC_1997 ---------ADGSPRVPHPPRDHHFADMDANDPYRTLPTGTTVGPNGERI
Mb2102c|M.bovis_AF2122/97 RRLAFQAL-----------------------HRPCNSAEWTAAVAGFAG-
Rv2077c|M.tuberculosis_H37Rv RRLAFQAL-----------------------HRPCNSAEWTAAVAGFAG-
MAV_0692|M.avium_104 -----------------------------------------AAIGGLAG-
MMAR_0116|M.marinum_M HMSDIDYA-----------------------RTHCTTSDWFDRTTLFASG
MUL_1136|M.ulcerans_Agy99 --------------------------------------------GPIAGG
Mflv_1972|M.gilvum_PYR-GCK AQSTVAGAGAGPGRDQLDALGHVLFEARGEVTSQTEVLEKLNAAADEVGQ
MSMEG_5600|M.smegmatis_MC2_155 LRARLADFGIHPG----------------EAPSSTSSGGDLTATATQIG-
TH_3926|M.thermoresistible__bu --------------------------------------AIGAARGALMG-
Mvan_5711|M.vanbaalenii_PYR-1 --------------------------------------ALGALRGAVLG-
MAB_0016|M.abscessus_ATCC_1997 ALVSRPPDDPAWAENQTKNGKSVYVTQTEAYDVTRQPPQSLGKLQGVDGS
.
Mb2102c|M.bovis_AF2122/97 ---------SSAGVVGTALAIPAGPADWALLGAALLGVGGSGAAVVNCAT
Rv2077c|M.tuberculosis_H37Rv ---------SSAGVVGTALAIPAGPADWALLGAALLGVGGSGAAVVNCAT
MAV_0692|M.avium_104 ---------APEAGVG---AIPGAIIGGAAGGIEAFIEGATESEPPKCGK
MMAR_0116|M.marinum_M --------LVSTGILTLTAETGVGGVAAVASGFGTLVAGKNLLGCLVGSK
MUL_1136|M.ulcerans_Agy99 --------PVPPGSIPHPVQPPHSHHGPPVLGKDELPDLGEFNPG-----
Mflv_1972|M.gilvum_PYR-GCK GRVPIPALPENADVQAFPAEPSAFTEGSRALSEGSFGLIPDVAHDIDVFR
MSMEG_5600|M.smegmatis_MC2_155 -----------AEIATFPPGTRADALAERMTGLHLNQADAARATDIAAAR
TH_3926|M.thermoresistible__bu ---------ILGGPIGVFGGGVLGFVGGAAGGALISGPARTAVTSAWDCL
Mvan_5711|M.vanbaalenii_PYR-1 ---------VLGGPLGMLGGSVAGFVGGAAGGAMISGPARTAVTSAWDCL
MAB_0016|M.abscessus_ATCC_1997 KVYQGSIVYDKASGRMYVVGNHGDGSGDTARGMWRSDPVDPNHPNDWVKT
.
Mb2102c|M.bovis_AF2122/97 K-------------------------------------------------
Rv2077c|M.tuberculosis_H37Rv K-------------------------------------------------
MAV_0692|M.avium_104 --------------------------------------------------
MMAR_0116|M.marinum_M --------------------------------------------------
MUL_1136|M.ulcerans_Agy99 --------------------------------------------------
Mflv_1972|M.gilvum_PYR-GCK NWSEASSDDRAGAVLDVAGAAPIP-GGKLVTEGLEHAVDAVNAGRHVDDA
MSMEG_5600|M.smegmatis_MC2_155 IWGETG------------GTSKMPDGSIIVLPANIRQTDVMKVFPDGSVT
TH_3926|M.thermoresistible__bu --------------------------------------------------
Mvan_5711|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_0016|M.abscessus_ATCC_1997 LRYQGDVPSLPGSRESSLVALPHGGVALFGADDYAPAEGRNMAVGAISAA
Mb2102c|M.bovis_AF2122/97 --------------------------------------------------
Rv2077c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_0692|M.avium_104 --------------------------------------------------
MMAR_0116|M.marinum_M --------------------------------------------------
MUL_1136|M.ulcerans_Agy99 --------------------------------------------------
Mflv_1972|M.gilvum_PYR-GCK LDAGSAGAHHLPDVPSAPHVDQTPDVGGPHGGGGADAGPVGNFGFEDANA
MSMEG_5600|M.smegmatis_MC2_155 VLRGVDVTQYLPR-------------------------------------
TH_3926|M.thermoresistible__bu --------------------------------------------------
Mvan_5711|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_0016|M.abscessus_ATCC_1997 TPEGLLQARPVTDLLPAGKTPWPGGAPYAALPTGVHWDPALRADVVDTRV
Mb2102c|M.bovis_AF2122/97 --------------------------------------------------
Rv2077c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_0692|M.avium_104 --------------------------------------------------
MMAR_0116|M.marinum_M --------------------------------------------------
MUL_1136|M.ulcerans_Agy99 --------------------------------------------------
Mflv_1972|M.gilvum_PYR-GCK LLQSSEANGGHLIERHVGMTSDDLAARMESSGLQTVSTFATADEAASAVS
MSMEG_5600|M.smegmatis_MC2_155 --------------------------------------------------
TH_3926|M.thermoresistible__bu --------------------------------------------------
Mvan_5711|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_0016|M.abscessus_ATCC_1997 SIWRDVPGVRGAYPPVTYQTSVPIFQPNS---------------------
Mb2102c|M.bovis_AF2122/97 --------------------------------------------------
Rv2077c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_0692|M.avium_104 --------------------------------------------------
MMAR_0116|M.marinum_M --------------------------------------------------
MUL_1136|M.ulcerans_Agy99 --------------------------------------------------
Mflv_1972|M.gilvum_PYR-GCK TALRENQDVLNSWIAEGAPRKLELEAPFDGGAVLVQGATEAVTGSTVRVV
MSMEG_5600|M.smegmatis_MC2_155 --------------------------------------------------
TH_3926|M.thermoresistible__bu --------------------------------------------------
Mvan_5711|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_0016|M.abscessus_ATCC_1997 --------------------------------------------------
Mb2102c|M.bovis_AF2122/97 ------------------
Rv2077c|M.tuberculosis_H37Rv ------------------
MAV_0692|M.avium_104 ------------------
MMAR_0116|M.marinum_M ------------------
MUL_1136|M.ulcerans_Agy99 ------------------
Mflv_1972|M.gilvum_PYR-GCK LKGDGNGGWYVLTGFPKP
MSMEG_5600|M.smegmatis_MC2_155 ------------------
TH_3926|M.thermoresistible__bu ------------------
Mvan_5711|M.vanbaalenii_PYR-1 ------------------
MAB_0016|M.abscessus_ATCC_1997 ------------------