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PATLSQILAWSTEHLIEAAAYWTQTADRWEDGFLTMRNQAQSITWRGAGGDALRERTQADLSVVSAKADL LRQAAGIARNGASDISAAQRRVVYGIEDAQNAGFTVGEDLSVTDMRSTSPAERAARQAQAEAFAADIRLR AEQLDGADTKVAGQLTAATAGLGGSGFAPASSPNSNHGAAAADRTTPGSNRNGVRLVDFKQDGGPQPQPQ PQPGAPQPAQQPSFLDQYKQALTSPGQPAQPAATPMPAFGPRPDPGPQPAPGPMPTVPPQPTFGQCVGGQ VKANVGKDMVKAGFETGIKGAIVGAAGGGIATPEFAGAGALPGAVLGFVGGFAKGVEEAPVKAALEGAAE CADVPIPGWMK*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_1479 | - | - | 100% (362) | hypothetical protein MAV_1479 |
| M. avium 104 | MAV_1450 | - | e-138 | 71.43% (371) | hypothetical protein MAV_1450 |
| M. avium 104 | MAV_2254 | - | 1e-98 | 56.50% (377) | hypothetical protein MAV_2254 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2102c | - | 2e-64 | 45.06% (344) | transmembrane protein |
| M. gilvum PYR-GCK | Mflv_1972 | - | 2e-24 | 34.84% (244) | hypothetical protein Mflv_1972 |
| M. tuberculosis H37Rv | Rv2077c | - | 2e-64 | 45.06% (344) | transmembrane protein |
| M. leprae Br4923 | MLBr_00222 | ftsH | 5e-06 | 30.83% (120) | putative integral membrane peptidase |
| M. abscessus ATCC 19977 | MAB_0016 | - | 8e-15 | 31.85% (157) | hypothetical protein MAB_0016 |
| M. marinum M | MMAR_0116 | - | 9e-77 | 62.55% (243) | hypothetical protein MMAR_0116 |
| M. smegmatis MC2 155 | MSMEG_5600 | - | 1e-23 | 39.16% (166) | hypothetical protein MSMEG_5600 |
| M. thermoresistible (build 8) | TH_3926 | - | 7e-20 | 35.14% (185) | PUTATIVE putative hypothetical protein Mvan_5711 |
| M. ulcerans Agy99 | MUL_1136 | - | 4e-50 | 50.22% (227) | hypothetical protein MUL_1136 |
| M. vanbaalenii PYR-1 | Mvan_5711 | - | 9e-19 | 34.31% (204) | hypothetical protein Mvan_5711 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1972|M.gilvum_PYR-GCK --------------MPSRSEVESWETADLDAAASRWRTAGDVLESAFEQH
MSMEG_5600|M.smegmatis_MC2_155 --MSPTATPAEGGEGLSRSRIESWDTTHLENATARWRATATELEGHFEQL
TH_3926|M.thermoresistible__bu -----MIDALPASGLPTLSQIQGWQTAHLRSAARRWRVTADTWTSIYDDI
Mvan_5711|M.vanbaalenii_PYR-1 -------MSVVAHGLPTLSQIENWETAHLACAARRWTAAAEHWESSFGLI
MAV_1479|M.avium_104 -------------MPATLSQILAWSTEHLIEAAAYWTQTADRWEDGFLTM
MMAR_0116|M.marinum_M -------------MPATLSQVRAWSTEHLIDTAGYWTKTADQWENAFFQM
Mb2102c|M.bovis_AF2122/97 -------------MLATLSQIRAWSTEHLIDAAGYWTETADRWEDVFLQM
Rv2077c|M.tuberculosis_H37Rv -------------MLATLSQIRAWSTEHLIDAAGYWTETADRWEDVFLQM
MUL_1136|M.ulcerans_Agy99 -------------MVLTLSQVQAWRTEHLIEAATYWSKTADQWEDVFLQM
MAB_0016|M.abscessus_ATCC_1997 --------------MPTKSEILNWRTDHLGAAAKTWGDQATQLDTAVNGA
MLBr_00222|M.leprae_Br4923 MLLMNRKNVIRMVTAIAVVVLLGWSFFYFSDDTRGYKFVDTSVAMSQING
: : * : : :
Mflv_1972|M.gilvum_PYR-GCK RQNILTPGGTAWEGDAKDAALDRVTADTSVVRRQGDVHRVAADIAARGSE
MSMEG_5600|M.smegmatis_MC2_155 RQHVLAPGGTEWEGDAKDAALERATQNLNTVRAAGDIARSAADLAENSSA
TH_3926|M.thermoresistible__bu AADLSAKSEIVWEGDASTAAQARTKRDRDTVELLAERLYFGASIAESGAA
Mvan_5711|M.vanbaalenii_PYR-1 ADGVRSPHGTQWEGAAQAAAQARADSDLAGVRMLADRLRTAARTAVDGGS
MAV_1479|M.avium_104 RN---QAQSITWRGAGGDALRERTQADLSVVSAKADLLRQAAGIARNGAS
MMAR_0116|M.marinum_M RN---QSYALGWSGAGGDALRERTSADLPIVGAKADMLRQAAGIAGNGAS
Mb2102c|M.bovis_AF2122/97 RN---QAHAIAWNGAGGDGLRQRTRADFSTVSGIADQLRRAATIARNGAG
Rv2077c|M.tuberculosis_H37Rv RN---QAHAIAWNGAGGDGLRQRTRADFSTVSGIADQLRRAATIARNGAG
MUL_1136|M.ulcerans_Agy99 RN---QSHTLVWEGAGGDALRQRTGADLAIVSTKADELRQASKIARDGAG
MAB_0016|M.abscessus_ATCC_1997 QG---LLDGLRGSGQFVEAFRTRLKSYIDKTRPKVDKLKSAKQVAESSEQ
MLBr_00222|M.leprae_Br4923 HN----VKSAQIDDREQQLRLTLKKGNNDTDGSDKVITKYPTGYAVDLFN
. *
Mflv_1972|M.gilvum_PYR-GCK DIQGARSRVLEAIAEA-----------------------------EQDDF
MSMEG_5600|M.smegmatis_MC2_155 DISAAKRDALQSISDA-----------------------------EADGF
TH_3926|M.thermoresistible__bu MVDQAKEEALLVVRVA-----------------------------GALAF
Mvan_5711|M.vanbaalenii_PYR-1 AIEAAKHEALTVIAAT-----------------------------NAMGF
MAV_1479|M.avium_104 DISAAQRRVVYGIEDA-----------------------------QNAGF
MMAR_0116|M.marinum_M DISAAQRRVLYAVEDA-----------------------------HNAGF
Mb2102c|M.bovis_AF2122/97 TIDAAQRRVMYAVEDA-----------------------------QDAGF
Rv2077c|M.tuberculosis_H37Rv TIDAAQRRVMYAVEDA-----------------------------QDAGF
MUL_1136|M.ulcerans_Agy99 TIGIAQRRVLHAVEDA-----------------------------HNAGF
MAB_0016|M.abscessus_ATCC_1997 QLKGAKDKAVYAVHDP-----------------------------EDEDF
MLBr_00222|M.leprae_Br4923 ALSAKNTKVTTAVNEGSILGELLVYVLPLLLLVGLFVMFSRMQGGARMGF
: . . : *
Mflv_1972|M.gilvum_PYR-GCK TVG----------------EDLSVTDNRAYDLET-AAARMTAATEHAEFI
MSMEG_5600|M.smegmatis_MC2_155 EVN----------------EDLSVRDTSRVDVST-MAARYTAAREHAENI
TH_3926|M.thermoresistible__bu DVR----------------EDLSLVDRLATGSPAATAVRLQQSNVLAATV
Mvan_5711|M.vanbaalenii_PYR-1 EVA----------------DDLTVWNRMG------AALRRNDAELLGISV
MAV_1479|M.avium_104 TVG----------------EDLSVTD-MRSTSPAERAARQAQAEAFAADI
MMAR_0116|M.marinum_M TVG----------------EDLSVTDTHRSGTPAEQAARQAQAQAFAGDI
Mb2102c|M.bovis_AF2122/97 NVG----------------EDLSVTDTKTTQPAAVQAARLAQAQALAGDI
Rv2077c|M.tuberculosis_H37Rv NVG----------------EDLSVTDTKTTQPAAVQAARLAQAQALAGDI
MUL_1136|M.ulcerans_Agy99 TVG----------------EDFSVTDIRTSRRSAEQAARQAQAQAQAQAT
MAB_0016|M.abscessus_ATCC_1997 NVN----------------EDLSVTE-RRSHSGLDRLKRAIRRRWLQGIL
MLBr_00222|M.leprae_Br4923 GFGKSRAKQLSKDMPKTTFADVAGVDEAVEELYEIKDFLQNPCRYQTLGA
. *.: :
Mflv_1972|M.gilvum_PYR-GCK RWRVEQLVATDALIGQQLQANAAE---------LEGIRFEGDRDGNGTDP
MSMEG_5600|M.smegmatis_MC2_155 QWNANQLLATDTLIGRRLTAKAAE---------LNGVRFDDEPEG-----
TH_3926|M.thermoresistible__bu RVGAAQLVSTDHAVAQRLREATDD---------FDSFDFAR---------
Mvan_5711|M.vanbaalenii_PYR-1 RTGAAQLAAVDHAVATELDSVTAG---------FDALNIGE---------
MAV_1479|M.avium_104 RLRAEQLDGADTKVAGQLTAATAG---------LGGSGFAPASSPNSN--
MMAR_0116|M.marinum_M RLHARQLDGADAKVAGQLTAATAD---------LSSVGFAQNPIPAT---
Mb2102c|M.bovis_AF2122/97 RLRVGQLVAAENEVSGQLAATTGD---------VGNVRFAG---------
Rv2077c|M.tuberculosis_H37Rv RLRVGQLVAAENEVSGQLAATTGD---------VGNVRFAG---------
MUL_1136|M.ulcerans_Agy99 DIRQRAVEPVPPPAPGRLPPLTPG---------EMAT-------------
MAB_0016|M.abscessus_ATCC_1997 HTRAQELVATDNAIARKLHEIAQD---------LSNFHLEGPDGNTDFSG
MLBr_00222|M.leprae_Br4923 KIPKGVLLYGPPGTGKTLLARAVAGEAGVPFFTISGSDFVEMFVGVGASR
: * :
Mflv_1972|M.gilvum_PYR-GCK TIRLVDNKTEDKGSQAESSEQRGAGSLSEESTGTWQDML------APEES
MSMEG_5600|M.smegmatis_MC2_155 ------------------------------------------------TI
TH_3926|M.thermoresistible__bu ------------------------------------------------NP
Mvan_5711|M.vanbaalenii_PYR-1 ------------------------------------------------GP
MAV_1479|M.avium_104 ------HGAAAADRTTPGSNRNGVRLVDFKQDGGPQP--------QPQPQ
MMAR_0116|M.marinum_M --------------QAPTTHRNGVQLVDFKQNGGEPPPF------APWDT
Mb2102c|M.bovis_AF2122/97 ---------------APVVAHSAVQLVDFFKQDGPTP-----------PP
Rv2077c|M.tuberculosis_H37Rv ---------------APVVAHSAVQLVDFFKQDGPTP-----------PP
MUL_1136|M.ulcerans_Agy99 --------------------------------------------------
MAB_0016|M.abscessus_ATCC_1997 DPNHPKIMGPAKPLGPIEQEDYDLGYTFLDENGNPLPMLDENGNVVIDPK
MLBr_00222|M.leprae_Br4923 VRDLFDQAKQNSPCIIFVDEIDAVGRQRGTGLGGGHDEREQTLNQLLVEM
Mflv_1972|M.gilvum_PYR-GCK AESAEGADTAESPLEALLGEGETA---EGQQRSSLDEALTEVAGKPVDAP
MSMEG_5600|M.smegmatis_MC2_155 RAASFGDGFKQSPFDDLLT--------KEQALAAWEKLQTDIASYNSRCA
TH_3926|M.thermoresistible__bu IIQPLSTDSDEHHFG-----------------TCFAESFKEDVGKNMVQG
Mvan_5711|M.vanbaalenii_PYR-1 VIAPIAAGDDGQSFG-----------------QCFADRFKDDIGENMVQG
MAV_1479|M.avium_104 PGAPQPAQQPS--FLDQYKQALTSPGQPAQPAATPMPAFGPRPDPGPQPA
MMAR_0116|M.marinum_M PDGTPPPGAPG--LSPELQQMILG-GDPAN-----LTGQGLLDN--LQQL
Mb2102c|M.bovis_AF2122/97 PGAPHPSGGADGPYSDPITSMMLP---PAG----TEAPVSDATKRWVDNM
Rv2077c|M.tuberculosis_H37Rv PGAPHPSGGADGPYSDPITSMMLP---PAG----TEAPVSDATKRWVDNM
MUL_1136|M.ulcerans_Agy99 PRLPAPPPQPP-----------------------------------IRGG
MAB_0016|M.abscessus_ATCC_1997 TGRPVPDSVWGDPADNNADGSPRVPHPPRDHHFADMDANDPYRTLPTGTT
MLBr_00222|M.leprae_Br4923 DGFGDRAGVILIAATNRPDILDPALLRPGRFDRQIPVSNPDLAGRRAVLR
Mflv_1972|M.gilvum_PYR-GCK PTALERILSQHTGTGRGEDRRYTQHPLEAPIVGADSSVIGDQQARVDAAH
MSMEG_5600|M.smegmatis_MC2_155 VNIVG--------------------PLPPPQYAACQQELAFLQG------
TH_3926|M.thermoresistible__bu VFVGG---------------------------------------------
Mvan_5711|M.vanbaalenii_PYR-1 VFVGG---------------------------------------------
MAV_1479|M.avium_104 PGPMP----------------------------TVPPQPTFGQCVGGQVK
MMAR_0116|M.marinum_M VQSLP----------------------------ENDPRTAWLRGQVADLQ
Mb2102c|M.bovis_AF2122/97 VNELA----------------------------ARPPD------DPIAVE
Rv2077c|M.tuberculosis_H37Rv VNELA----------------------------ARPPD------DPIAVE
MUL_1136|M.ulcerans_Agy99 ADLAP----------------------------AEPPP------------
MAB_0016|M.abscessus_ATCC_1997 VGPNG-----------------------ERIALVSRPPDDPAWAENQTKN
MLBr_00222|M.leprae_Br4923 VHSKGK--------------PIADDADLDGLAKRTVGMTGADLANVVNEA
Mflv_1972|M.gilvum_PYR-GCK ESVESAQGALDDALAQSTVAGAGAGPGRDQLDALGHVLFEARGEVTSQTE
MSMEG_5600|M.smegmatis_MC2_155 ----------QEAALRARLADFGIHPG----------------EAPSSTS
TH_3926|M.thermoresistible__bu ------------AIGAARGALMGILGG-----------------------
Mvan_5711|M.vanbaalenii_PYR-1 ------------ALGALRGAVLGVLGG-----------------------
MAV_1479|M.avium_104 ANVG-KDMVKAGFETGIKGAIVGAAGGG----------------------
MMAR_0116|M.marinum_M AHMSDIDYARTHCTTSDWFDRTTLFASG----------------------
Mb2102c|M.bovis_AF2122/97 ARRLAFQALHRPCNSAEWTAAVAGFAG-----------------------
Rv2077c|M.tuberculosis_H37Rv ARRLAFQALHRPCNSAEWTAAVAGFAG-----------------------
MUL_1136|M.ulcerans_Agy99 -------VVRTPMEPPARLG--GPIAGG----------------------
MAB_0016|M.abscessus_ATCC_1997 GKSVYVTQTEAYDVTRQPPQSLGKLQG-----------------------
MLBr_00222|M.leprae_Br4923 ALLTARENGLVITGPALEEAVDRVIGGPRRKGRIISEQEKKITAYHEGGH
.
Mflv_1972|M.gilvum_PYR-GCK VLEKLNAAADEVGQGRVPIPALPENADVQAFPAEPSAFTEGSRALSEGSF
MSMEG_5600|M.smegmatis_MC2_155 SGGDLTATATQIG------------AEIATFPPGTRADALAERMTGLHLN
TH_3926|M.thermoresistible__bu --------------------------PIGVFGGGVLGFVGGAAGGALISG
Mvan_5711|M.vanbaalenii_PYR-1 --------------------------PLGMLGGSVAGFVGGAAGGAMISG
MAV_1479|M.avium_104 -------------------------IATPEFAGAGALP--GAVLGFVGGF
MMAR_0116|M.marinum_M -------------------------LVSTGILTLTAETGVGGVAAVASGF
Mb2102c|M.bovis_AF2122/97 --------------------------SSAGVVGTALAIPAGPADWALLGA
Rv2077c|M.tuberculosis_H37Rv --------------------------SSAGVVGTALAIPAGPADWALLGA
MUL_1136|M.ulcerans_Agy99 -------------------------PVPPGSIPHPVQPPHSHHGPPVLGK
MAB_0016|M.abscessus_ATCC_1997 -------------------------VDGSKVYQGSIVYDKASGRMYVVGN
MLBr_00222|M.leprae_Br4923 TLAAWAMPDIEPIYKVTILARGRTGGHAVAVPEEDKGLRTRSEMIAQLVF
Mflv_1972|M.gilvum_PYR-GCK GLIPDVAHDIDVFRNWSEASSDDRAGAVLDVAGAAPIP-GGKLVTEGLEH
MSMEG_5600|M.smegmatis_MC2_155 QADAARATDIAAARIWGETG------------GTSKMPDGSIIVLPANIR
TH_3926|M.thermoresistible__bu PARTAVTSAWDCL-------------------------------------
Mvan_5711|M.vanbaalenii_PYR-1 PARTAVTSAWDCL-------------------------------------
MAV_1479|M.avium_104 AKGVEEAPVKAALEGAAECADVPIPGWMK---------------------
MMAR_0116|M.marinum_M GTLVAGKNLLGCLVGSK---------------------------------
Mb2102c|M.bovis_AF2122/97 ALLGVGGSGAAVVNCATK--------------------------------
Rv2077c|M.tuberculosis_H37Rv ALLGVGGSGAAVVNCATK--------------------------------
MUL_1136|M.ulcerans_Agy99 DELPDLGEFNPG--------------------------------------
MAB_0016|M.abscessus_ATCC_1997 HGDGSGDTARGMWRSDPVDPNHPNDWVKTLRYQGDVPSLPGSRESSLVAL
MLBr_00222|M.leprae_Br4923 AMGGRAAEELVFREPTTGAVSDIEKATKIARSMVTEFGMSSKLGAVRYGS
Mflv_1972|M.gilvum_PYR-GCK AVDAVNAGRHVDDALDAGSAGAHHLPDVPSAPHVDQTPDVGGPHGGGGAD
MSMEG_5600|M.smegmatis_MC2_155 QTDVMKVFPDGSVTVLRGVDVTQYLPR-----------------------
TH_3926|M.thermoresistible__bu --------------------------------------------------
Mvan_5711|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_1479|M.avium_104 --------------------------------------------------
MMAR_0116|M.marinum_M --------------------------------------------------
Mb2102c|M.bovis_AF2122/97 --------------------------------------------------
Rv2077c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_1136|M.ulcerans_Agy99 --------------------------------------------------
MAB_0016|M.abscessus_ATCC_1997 PHGGVALFGADDYAPAEGRNMAVGAISAATPEGLLQARPVTDLLPAGKTP
MLBr_00222|M.leprae_Br4923 EHGDPFLGRTMGTQADYSHEVARDIDDEVRKLIEAAHTEAWEILTEYRDV
Mflv_1972|M.gilvum_PYR-GCK AGPVGNFGFEDANALLQSSEANGGHLIERHVGMTSDDLAARMESSGLQTV
MSMEG_5600|M.smegmatis_MC2_155 --------------------------------------------------
TH_3926|M.thermoresistible__bu --------------------------------------------------
Mvan_5711|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_1479|M.avium_104 --------------------------------------------------
MMAR_0116|M.marinum_M --------------------------------------------------
Mb2102c|M.bovis_AF2122/97 --------------------------------------------------
Rv2077c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_1136|M.ulcerans_Agy99 --------------------------------------------------
MAB_0016|M.abscessus_ATCC_1997 WPGGAPYAALPTGVHWDPALRADVVDTRVSIWRDVPGVRGAYPPVTYQTS
MLBr_00222|M.leprae_Br4923 LDTLAGELLEKETLHRPELEGIFASVEKRPRLTMFDDFGGRIPSDKPPIK
Mflv_1972|M.gilvum_PYR-GCK STFATADEAASAVSTALRENQDVLNSWIAEGAPRKLELEAPFDGGAVLVQ
MSMEG_5600|M.smegmatis_MC2_155 --------------------------------------------------
TH_3926|M.thermoresistible__bu --------------------------------------------------
Mvan_5711|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_1479|M.avium_104 --------------------------------------------------
MMAR_0116|M.marinum_M --------------------------------------------------
Mb2102c|M.bovis_AF2122/97 --------------------------------------------------
Rv2077c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_1136|M.ulcerans_Agy99 --------------------------------------------------
MAB_0016|M.abscessus_ATCC_1997 VPIFQPNS------------------------------------------
MLBr_00222|M.leprae_Br4923 TPGELAIERGEPWPQPVPEPAFKAAIARASQAAEASHQAAQSDTDGPPGQ
Mflv_1972|M.gilvum_PYR-GCK GATEAVTGSTVRVVLKGDGNGGWYVLTGFPKP------------------
MSMEG_5600|M.smegmatis_MC2_155 --------------------------------------------------
TH_3926|M.thermoresistible__bu --------------------------------------------------
Mvan_5711|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_1479|M.avium_104 --------------------------------------------------
MMAR_0116|M.marinum_M --------------------------------------------------
Mb2102c|M.bovis_AF2122/97 --------------------------------------------------
Rv2077c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_1136|M.ulcerans_Agy99 --------------------------------------------------
MAB_0016|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00222|M.leprae_Br4923 GANGSHAGDRQRQHGPTQPDYGAPPGWHAPGWPPQQPPDYWYPPEQQPSQ
Mflv_1972|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_5600|M.smegmatis_MC2_155 --------------------------------------------------
TH_3926|M.thermoresistible__bu --------------------------------------------------
Mvan_5711|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_1479|M.avium_104 --------------------------------------------------
MMAR_0116|M.marinum_M --------------------------------------------------
Mb2102c|M.bovis_AF2122/97 --------------------------------------------------
Rv2077c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_1136|M.ulcerans_Agy99 --------------------------------------------------
MAB_0016|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00222|M.leprae_Br4923 SPYWPQPAPSYPGQAPPPYPSYPPCPSYPPPGQSAPDAGKPPAQLDEGVS
Mflv_1972|M.gilvum_PYR-GCK --------
MSMEG_5600|M.smegmatis_MC2_155 --------
TH_3926|M.thermoresistible__bu --------
Mvan_5711|M.vanbaalenii_PYR-1 --------
MAV_1479|M.avium_104 --------
MMAR_0116|M.marinum_M --------
Mb2102c|M.bovis_AF2122/97 --------
Rv2077c|M.tuberculosis_H37Rv --------
MUL_1136|M.ulcerans_Agy99 --------
MAB_0016|M.abscessus_ATCC_1997 --------
MLBr_00222|M.leprae_Br4923 PSNPPAHG