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MPGLPTLSEVRAANWDHLRTNAAAWRSLGRTWESAFTEVHNASLRPGGTDWTGAGAEAFQDRAYLDLVKI RHPADITDTVAGIAERGADAQDGNKRSILDTVDEVEGDNFQVGEDWSVTDRITWYSSAAELEQREQAAQE HRSFLMSKVYKLVGDEADISRNLTTASADLHGFSFGDEGADGGAGDGQPHVVLVDDVHRDPTIKGPAATP QHEQNGYDLQDQFQDGQGPVFGGDPRDGVPRSPASELAQGPPGTRPLPTGTALGPDGHRYAFFSHPDGTE VPGVNQFVTNGAVWDYTDPAHPVKVGDLPGIYQASGVYDAATNQMVIVGNTSNRNGDLTRGMWVSGPIDP AQPNSWISSLQHVGDVSLPGDRESQLVALSGGGYMLVGATNGGPVQAISAATPQGLMGAAPQTLLSQGQL PTVYGPTVMGTSLDPATGVEQIQLRVSTWPPGPTYDPNTWTTTFDVQH
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_0500 | - | - | 100% (468) | hypothetical protein MAV_0500 |
| M. avium 104 | MAV_2254 | - | 2e-20 | 30.14% (292) | hypothetical protein MAV_2254 |
| M. avium 104 | MAV_1479 | - | 1e-19 | 28.68% (272) | hypothetical protein MAV_1479 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2102c | - | 6e-17 | 29.30% (215) | transmembrane protein |
| M. gilvum PYR-GCK | Mflv_1972 | - | 1e-24 | 33.05% (239) | hypothetical protein Mflv_1972 |
| M. tuberculosis H37Rv | Rv2077c | - | 6e-17 | 29.30% (215) | transmembrane protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0016 | - | 1e-51 | 32.89% (529) | hypothetical protein MAB_0016 |
| M. marinum M | MMAR_0116 | - | 4e-20 | 30.80% (263) | hypothetical protein MMAR_0116 |
| M. smegmatis MC2 155 | MSMEG_5600 | - | 1e-20 | 33.33% (174) | hypothetical protein MSMEG_5600 |
| M. thermoresistible (build 8) | TH_3926 | - | 1e-10 | 28.90% (173) | PUTATIVE putative hypothetical protein Mvan_5711 |
| M. ulcerans Agy99 | MUL_1136 | - | 9e-13 | 34.09% (132) | hypothetical protein MUL_1136 |
| M. vanbaalenii PYR-1 | Mvan_5711 | - | 7e-13 | 35.25% (122) | hypothetical protein Mvan_5711 |
CLUSTAL 2.0.9 multiple sequence alignment
TH_3926|M.thermoresistible__bu ---MIDALPASGLPTLSQIQGWQTAHLRSAARRWRVTADTWTSIYDDIAA
Mvan_5711|M.vanbaalenii_PYR-1 -----MSVVAHGLPTLSQIENWETAHLACAARRWTAAAEHWESSFGLIAD
Mb2102c|M.bovis_AF2122/97 -----------MLATLSQIRAWSTEHLIDAAGYWTETADRWEDVFLQMRN
Rv2077c|M.tuberculosis_H37Rv -----------MLATLSQIRAWSTEHLIDAAGYWTETADRWEDVFLQMRN
MMAR_0116|M.marinum_M -----------MPATLSQVRAWSTEHLIDTAGYWTKTADQWENAFFQMRN
MUL_1136|M.ulcerans_Agy99 -----------MVLTLSQVQAWRTEHLIEAATYWSKTADQWEDVFLQMRN
Mflv_1972|M.gilvum_PYR-GCK ------------MPSRSEVESWETADLDAAASRWRTAGDVLESAFEQHRQ
MSMEG_5600|M.smegmatis_MC2_155 MSPTATPAEGGEGLSRSRIESWDTTHLENATARWRATATELEGHFEQLRQ
MAV_0500|M.avium_104 ---------MPGLPTLSEVRAANWDHLRTNAAAWRSLGRTWESAFTEVHN
MAB_0016|M.abscessus_ATCC_1997 ------------MPTKSEILNWRTDHLGAAAKTWGDQATQLD---TAVNG
: *.: .* : * .
TH_3926|M.thermoresistible__bu DLSAKSEIVWEGDASTAAQARTKRDRDTVELLAERLYFGASIAESGAAMV
Mvan_5711|M.vanbaalenii_PYR-1 GVRSPHGTQWEGAAQAAAQARADSDLAGVRMLADRLRTAARTAVDGGSAI
Mb2102c|M.bovis_AF2122/97 QAHAIA---WNGAGGDGLRQRTRADFSTVSGIADQLRRAATIARNGAGTI
Rv2077c|M.tuberculosis_H37Rv QAHAIA---WNGAGGDGLRQRTRADFSTVSGIADQLRRAATIARNGAGTI
MMAR_0116|M.marinum_M QSYALG---WSGAGGDALRERTSADLPIVGAKADMLRQAAGIAGNGASDI
MUL_1136|M.ulcerans_Agy99 QSHTLV---WEGAGGDALRQRTGADLAIVSTKADELRQASKIARDGAGTI
Mflv_1972|M.gilvum_PYR-GCK NILTPGGTAWEGDAKDAALDRVTADTSVVRRQGDVHRVAADIAARGSEDI
MSMEG_5600|M.smegmatis_MC2_155 HVLAPGGTEWEGDAKDAALERATQNLNTVRAAGDIARSAADLAENSSADI
MAV_0500|M.avium_104 ASLRPGGTDWTGAGAEAFQDRAYLDLVKIRHPADITDTVAGIAERGADAQ
MAB_0016|M.abscessus_ATCC_1997 AQGLLDGLRGSGQFVEAFRTRLKSYIDKTRPKVDKLKSAKQVAESSEQQL
* . * : * .
TH_3926|M.thermoresistible__bu DQAKEEALLVVRVAGALAFDVREDLSLVDRLATGS-PAATAVRLQQSNVL
Mvan_5711|M.vanbaalenii_PYR-1 EAAKHEALTVIAATNAMGFEVADDLTVWNRMG-------AALRRNDAELL
Mb2102c|M.bovis_AF2122/97 DAAQRRVMYAVEDAQDAGFNVGEDLSVTDTKTTQP-AAVQAARLAQAQAL
Rv2077c|M.tuberculosis_H37Rv DAAQRRVMYAVEDAQDAGFNVGEDLSVTDTKTTQP-AAVQAARLAQAQAL
MMAR_0116|M.marinum_M SAAQRRVLYAVEDAHNAGFTVGEDLSVTDTHRSGT-PAEQAARQAQAQAF
MUL_1136|M.ulcerans_Agy99 GIAQRRVLHAVEDAHNAGFTVGEDFSVTDIRTSRR-SAEQAARQAQAQAQ
Mflv_1972|M.gilvum_PYR-GCK QGARSRVLEAIAEAEQDDFTVGEDLSVTDNRAYD--LETAAARMTAATEH
MSMEG_5600|M.smegmatis_MC2_155 SAAKRDALQSISDAEADGFEVNEDLSVRDTSRVD--VSTMAARYTAAREH
MAV_0500|M.avium_104 DGNKRSILDTVDEVEGDNFQVGEDWSVTDRITWYSSAAELEQREQAAQEH
MAB_0016|M.abscessus_ATCC_1997 KGAKDKAVYAVHDPEDEDFNVNEDLSVTERRSHSG--LDRLKRAIRRRWL
: : : * * :* :: : *
TH_3926|M.thermoresistible__bu AATVRVGAAQLVSTDHAVAQRLREATDDFDSFDFARNPII----------
Mvan_5711|M.vanbaalenii_PYR-1 GISVRTGAAQLAAVDHAVATELDSVTAGFDALNIGEGPVI----------
Mb2102c|M.bovis_AF2122/97 AGDIRLRVGQLVAAENEVSGQLAATTGDVGNVRFAGAPVV----------
Rv2077c|M.tuberculosis_H37Rv AGDIRLRVGQLVAAENEVSGQLAATTGDVGNVRFAGAPVV----------
MMAR_0116|M.marinum_M AGDIRLHARQLDGADAKVAGQLTAATADLSSVGFAQNPIP----------
MUL_1136|M.ulcerans_Agy99 AQATDIRQRAVEPVPPPAPGRLPPLTPGEMAT--PRLPAP----------
Mflv_1972|M.gilvum_PYR-GCK AEFIRWRVEQLVATDALIGQQLQANAAELEGIRFEGDRDGNGTDPTIRLV
MSMEG_5600|M.smegmatis_MC2_155 AENIQWNANQLLATDTLIGRRLTAKAAELNGVRFDDEPEG----------
MAV_0500|M.avium_104 RSFLMSKVYKLVGDEADISRNLTTASADLHGFSFGDEGADGGAGDGQPHV
MAB_0016|M.abscessus_ATCC_1997 QGILHTRAQELVATDNAIARKLHEIAQDLSNFHLEGPDGNTDFSGDPNHP
: .* :
TH_3926|M.thermoresistible__bu -----------------------------------------QPLSTDSDE
Mvan_5711|M.vanbaalenii_PYR-1 -----------------------------------------APIAAGDDG
Mb2102c|M.bovis_AF2122/97 -----------------------------------------AHSAVQLVD
Rv2077c|M.tuberculosis_H37Rv -----------------------------------------AHSAVQLVD
MMAR_0116|M.marinum_M -----------------------------------------ATQAPTTHR
MUL_1136|M.ulcerans_Agy99 -----------------------------------------PPQPPIR--
Mflv_1972|M.gilvum_PYR-GCK DNKTEDKGSQAESSEQRGAGSLSEESTGTWQDMLAPEESAESAEGADTAE
MSMEG_5600|M.smegmatis_MC2_155 -------------------------------------TIRAASFGDGFKQ
MAV_0500|M.avium_104 VLVDDVHRDP----------------------TIKG---PAATPQHEQNG
MAB_0016|M.abscessus_ATCC_1997 KIMGPAKPLG----------------------PIEQEDYDLGYTFLDENG
TH_3926|M.thermoresistible__bu ---------------HHFGTCFAESFKEDVGKNMVQGVFVG---------
Mvan_5711|M.vanbaalenii_PYR-1 ---------------QSFGQCFADRFKDDIGENMVQGVFVG---------
Mb2102c|M.bovis_AF2122/97 ------FFKQDGPTPPPPGAPHPSGGADGPYSDPITSMMLPPA-------
Rv2077c|M.tuberculosis_H37Rv ------FFKQDGPTPPPPGAPHPSGGADGPYSDPITSMMLPPA-------
MMAR_0116|M.marinum_M NGVQLVDFKQNGGEPPPFAPWDTPDGTPPPGAPGLSPELQQMI-------
MUL_1136|M.ulcerans_Agy99 -----------GG--ADLAPAEPPPVVRTPMEP-----------------
Mflv_1972|M.gilvum_PYR-GCK SPLEALLGEGETAEGQQRSSLDEALTEVAGKPVDAPPTALERILSQHTGT
MSMEG_5600|M.smegmatis_MC2_155 SPFDDLLT-----KEQALAAWEKLQTDIASYNSRCAVNIVG---------
MAV_0500|M.avium_104 YDLQDQFQDG---QGPVFGGDPRDGVPRSPASELAQGPP-----------
MAB_0016|M.abscessus_ATCC_1997 NPLPMLDENGNVVIDPKTGRPVPDSVWGDPADNNADGSPRVPHPPRDHHF
.
TH_3926|M.thermoresistible__bu ---------------GAIGAARG---------------------------
Mvan_5711|M.vanbaalenii_PYR-1 ---------------GALGALRG---------------------------
Mb2102c|M.bovis_AF2122/97 -----------GTEAPVSDATKRWVDNMVN--------------------
Rv2077c|M.tuberculosis_H37Rv -----------GTEAPVSDATKRWVDNMVN--------------------
MMAR_0116|M.marinum_M -----------LGGDPANLTGQGLLDNLQQ--------------------
MUL_1136|M.ulcerans_Agy99 ---------------PARLGGP----------------------------
Mflv_1972|M.gilvum_PYR-GCK GRGEDRRYTQHPLEAPIVGADSSVIGDQQARVDAAHESVESAQGALDDAL
MSMEG_5600|M.smegmatis_MC2_155 -----------PLPPPQYAACQQELAFLQG----------------QEAA
MAV_0500|M.avium_104 -------GTRPLPTGTALGPDGHRYAFFSH--------------------
MAB_0016|M.abscessus_ATCC_1997 ADMDANDPYRTLPTGTTVGPNGERIALVSR--------------------
TH_3926|M.thermoresistible__bu --------------------------------------------------
Mvan_5711|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb2102c|M.bovis_AF2122/97 --------------------------------------ELAARPPDDP--
Rv2077c|M.tuberculosis_H37Rv --------------------------------------ELAARPPDDP--
MMAR_0116|M.marinum_M --------------------------------------LVQSLPENDPRT
MUL_1136|M.ulcerans_Agy99 --------------------------------------------------
Mflv_1972|M.gilvum_PYR-GCK AQSTVAGAGAGPGRDQLDALGHVLFEARGEVTSQTEVLEKLNAAADEVGQ
MSMEG_5600|M.smegmatis_MC2_155 LRARLADFGIHPG----------------EAPSSTSSGGDLTATATQIG-
MAV_0500|M.avium_104 --------------------------------------PDGTEVPGVNQF
MAB_0016|M.abscessus_ATCC_1997 --------------------------------------PPDDPAWAENQT
TH_3926|M.thermoresistible__bu -------------------------------ALMGILGGPIGVFGGGVLG
Mvan_5711|M.vanbaalenii_PYR-1 -------------------------------AVLGVLGGPLGMLGGSVAG
Mb2102c|M.bovis_AF2122/97 -------IAVEARRLAFQALHRPCNSAEWTAAVAGFAGSSAGVVGTALAI
Rv2077c|M.tuberculosis_H37Rv -------IAVEARRLAFQALHRPCNSAEWTAAVAGFAGSSAGVVGTALAI
MMAR_0116|M.marinum_M AWLRGQVADLQAHMSDIDYARTHCTTSDWFDRTTLFASGLVSTGILTLTA
MUL_1136|M.ulcerans_Agy99 -----------------------------------IAGGPVPPGSIPHPV
Mflv_1972|M.gilvum_PYR-GCK GRVPIPALPENADVQAFPAEPSAFTEGSRALSEGSFGLIPDVAHDIDVFR
MSMEG_5600|M.smegmatis_MC2_155 -----------AEIATFPPGTRADALAERMTGLHLNQADAARATDIAAAR
MAV_0500|M.avium_104 VTNGAVWDYTDPAHPVKVG-----------DLPGIYQASGVYDAATNQMV
MAB_0016|M.abscessus_ATCC_1997 KNGKSVYVTQTEAYDVTRQPPQSLGKLQGVDGSKVYQGSIVYDKASGRMY
TH_3926|M.thermoresistible__bu FVG------------------GAAGGALISGPARTAVTSAWDCL------
Mvan_5711|M.vanbaalenii_PYR-1 FVG------------------GAAGGAMISGPARTAVTSAWDCL------
Mb2102c|M.bovis_AF2122/97 PAG---------------PADWALLGAALLGVGGSGAAVVNCATK-----
Rv2077c|M.tuberculosis_H37Rv PAG---------------PADWALLGAALLGVGGSGAAVVNCATK-----
MMAR_0116|M.marinum_M ETGVGG-----------VAAVASGFGTLVAGKNLLGCLVGSK--------
MUL_1136|M.ulcerans_Agy99 QP------------------PHSHHGPPVLGKDELPDLGEFNPG------
Mflv_1972|M.gilvum_PYR-GCK NWSEASSDDRAGAVLDVAGAAPIP-GGKLVTEGLEHAVDAVNAGRHVDDA
MSMEG_5600|M.smegmatis_MC2_155 IWGETG------------GTSKMPDGSIIVLPANIRQTDVMKVFPDGSVT
MAV_0500|M.avium_104 IVGNTS-----------NRNGDLTRGMWVSGPIDPAQPNSWISSLQHVGD
MAB_0016|M.abscessus_ATCC_1997 VVGNHG-----------DGSGDTARGMWRSDPVDPNHPNDWVKTLRYQGD
*
TH_3926|M.thermoresistible__bu --------------------------------------------------
Mvan_5711|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb2102c|M.bovis_AF2122/97 --------------------------------------------------
Rv2077c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_0116|M.marinum_M --------------------------------------------------
MUL_1136|M.ulcerans_Agy99 --------------------------------------------------
Mflv_1972|M.gilvum_PYR-GCK LDAGSAGAHHLPDVPSAPHVDQTPDVGGPHGGGGADAGPVGNFGFEDANA
MSMEG_5600|M.smegmatis_MC2_155 VLRGVDVTQYLPR-------------------------------------
MAV_0500|M.avium_104 VS-LPGDRESQLVALSG---------GGYMLVGATNGGPVQ-------AI
MAB_0016|M.abscessus_ATCC_1997 VPSLPGSRESSLVALPH---------GGVALFGADDYAPAEGRNMAVGAI
TH_3926|M.thermoresistible__bu --------------------------------------------------
Mvan_5711|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb2102c|M.bovis_AF2122/97 --------------------------------------------------
Rv2077c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_0116|M.marinum_M --------------------------------------------------
MUL_1136|M.ulcerans_Agy99 --------------------------------------------------
Mflv_1972|M.gilvum_PYR-GCK LLQSSEANGGHLIERHVGMTSDDLAARMESSGLQTVSTFATADEAASAVS
MSMEG_5600|M.smegmatis_MC2_155 --------------------------------------------------
MAV_0500|M.avium_104 SAATPQGLMGAAPQT-LLSQGQLPT----VYGPTVMGTSLDPATGVEQIQ
MAB_0016|M.abscessus_ATCC_1997 SAATPEGLLQARPVTDLLPAGKTPWPGGAPYAALPTGVHWDPALRADVVD
TH_3926|M.thermoresistible__bu --------------------------------------------------
Mvan_5711|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb2102c|M.bovis_AF2122/97 --------------------------------------------------
Rv2077c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_0116|M.marinum_M --------------------------------------------------
MUL_1136|M.ulcerans_Agy99 --------------------------------------------------
Mflv_1972|M.gilvum_PYR-GCK TALRENQDVLNSWIAEGAPRKLELEAPFDGGAVLVQGATEAVTGSTVRVV
MSMEG_5600|M.smegmatis_MC2_155 --------------------------------------------------
MAV_0500|M.avium_104 LRVSTWPPGP----TYDPNTWTTTFDVQH---------------------
MAB_0016|M.abscessus_ATCC_1997 TRVSIWRDVPGVRGAYPPVTYQTSVPIFQPNS------------------
TH_3926|M.thermoresistible__bu ------------------
Mvan_5711|M.vanbaalenii_PYR-1 ------------------
Mb2102c|M.bovis_AF2122/97 ------------------
Rv2077c|M.tuberculosis_H37Rv ------------------
MMAR_0116|M.marinum_M ------------------
MUL_1136|M.ulcerans_Agy99 ------------------
Mflv_1972|M.gilvum_PYR-GCK LKGDGNGGWYVLTGFPKP
MSMEG_5600|M.smegmatis_MC2_155 ------------------
MAV_0500|M.avium_104 ------------------
MAB_0016|M.abscessus_ATCC_1997 ------------------