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RIITVEEHFQHPEVSARVAELTGPAVEGLAEFGNAFSLDPDSTARLGGNRLAHMDQVGIDVQVVSHGNGS PGTLQHPEAVELCRRVNNDLAAQIAENPDRFRGFATLPLYDPAAAAEELRRCVGDLGFVGALIAGSYDGL FLDDERFDPILTAAEAVDFPIYVHPGLPEAPVSQRYYAGSWPASVHMMFSGPAFGWHAEAGIHIVRLILS GALDRHPTLKLLSGHWGELAAFYLERLDETLGLLPTGLERAPSDYYRQQVWITPSGMYNQNQLNFMTAEL GAQRIIYSEDFPYVVRDNVSTFLEQAGLSEADTHAIAHTNAEALLRI*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_0481 | - | - | 100% (328) | amidohydrolase family protein |
| M. avium 104 | MAV_2577 | - | 3e-09 | 26.80% (153) | amidohydrolase family protein |
| M. avium 104 | MAV_0646 | - | 8e-09 | 23.32% (283) | amidohydrolase family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_0351 | - | 3e-09 | 26.14% (153) | amidohydrolase 2 |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0299 | - | 4e-24 | 30.04% (283) | putative amidohydrolase (aminocarboxymuconate-semialdehyde |
| M. marinum M | MMAR_0083 | - | 5e-11 | 27.54% (207) | amidohydrolase |
| M. smegmatis MC2 155 | MSMEG_4063 | - | 1e-108 | 63.70% (292) | amidohydrolase family protein |
| M. thermoresistible (build 8) | TH_0554 | - | 3e-07 | 27.56% (127) | amidohydrolase family protein |
| M. ulcerans Agy99 | MUL_3878 | - | 8e-09 | 31.36% (118) | metal-dependent hydrolase |
| M. vanbaalenii PYR-1 | Mvan_0901 | - | 4e-13 | 25.00% (308) | amidohydrolase 2 |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_0481|M.avium_104 ---------------------------------------MRIITVEEHFQ
MSMEG_4063|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0351|M.gilvum_PYR-GCK MPEPAPQFRDAPIFDADQHMYETPDALTKFLPDRYTR-AVQYGQFGRHTR
TH_0554|M.thermoresistible__bu ---MSPRSLPYPVFDIDNHMYETTDALIKFLPREHRG-KVGYVELNGRKK
MUL_3878|M.ulcerans_Agy99 -----MDSLGYKAIDVDNHYYEPLDAFTRHLDKKFRRRGVQLVTDGRHTQ
MAB_0299|M.abscessus_ATCC_1997 ---------------------------------------MTSVRIDIHAH
Mvan_0901|M.vanbaalenii_PYR-1 ------MGSSTLIIDTDTHITEPPDLWTSRMSKSRWGNLIPEVKWVEEKQ
MMAR_0083|M.marinum_M --------------------------------------------------
MAV_0481|M.avium_104 --HPEVSARVAELTGPAVEGLAEFG--------------------NAFSL
MSMEG_4063|M.smegmatis_MC2_155 -------------MDDSYEALLQH-----------------------FMP
Mflv_0351|M.gilvum_PYR-GCK --IVINNRVSDFIPNPTFERVAAPGAHEKFFAGENTEGLT-LREMQGPAI
TH_0554|M.thermoresistible__bu --LMVKDRISHMIPNPTFEKVARPGSAEDYFLGNNPEGLN-FREFVGEPM
MUL_3878|M.ulcerans_Agy99 --VIIGDRVNRFIPNPTFDPIIVPGCLDLLFRGEIPDGVDPASLMKVEKL
MAB_0299|M.abscessus_ATCC_1997 --LWSDEYLSLLDGYGRPATDVHRG------------------------L
Mvan_0901|M.vanbaalenii_PYR-1 GEYWCMDGQPVFTVGTCIMVPGEDG---------KPVRSPRFPDYADRFS
MMAR_0083|M.marinum_M ---MTFVDVHFHLAPASFIRQKPNR-----------------------VF
MAV_0481|M.avium_104 DPDSTARLGGNRLAHMDQVGIDVQVVSHGN----GSPGTLQHPEAVELCR
MSMEG_4063|M.smegmatis_MC2_155 DRDSSERLGGRRLTHMDRVGIDVQVVSHGA----NNPGSLNHHEATELCR
Mflv_0351|M.gilvum_PYR-GCK EAPAATRNPADRVAELDRQGVREALNYPTL----ASLIEHATADDPELTL
TH_0554|M.thermoresistible__bu EVIPAFQHPAPRLELMDELGIDRCVMYPTL----ASLIEERTTDDVVLTH
MUL_3878|M.ulcerans_Agy99 ELRPEYRNRDARVVVVESQGIETIFMFPTF----GCGVEEALKADIEATA
MAB_0299|M.abscessus_ATCC_1997 GAGATRDDLDGRFELMDEAGVDLQILTATP----ASPHFEDQAAAVASAR
Mvan_0901|M.vanbaalenii_PYR-1 SMHPSAYDAKARLEVMDAYGIQAAAIFPNLGFVGPNIFAAAGPDALEFQT
MMAR_0083|M.marinum_M DIYPQLGDGALGRQELAAAGGRAFVSLPWP-----VPPGADVEATATATS
. : *
MAV_0481|M.avium_104 RVNNDLAAQIAENPD------RFRGFATLPLYDPAAAAEELRRCVGDLGF
MSMEG_4063|M.smegmatis_MC2_155 TANDALAQDISEHPT------RFRGFATIPLHDPHAAADEMRRCVNELGF
Mflv_0351|M.gilvum_PYR-GCK AVIHALNQWMAEHWTFDYQG-RVFSTPIINLSEVDGAQRELEYILTQGAR
TH_0554|M.thermoresistible__bu AVMHALNQWMHEHWSFDYEG-RIFATPVITLPIVEEAIRELHWCLERGMR
MUL_3878|M.ulcerans_Agy99 ASLHAFNLWLDEDWGFDRPDHRIIAAPMISLADPEKALQEVEFVLERGAR
MAB_0299|M.abscessus_ATCC_1997 FINDEYAKLSSEYPG------RFGALASLPLPHVPAALEELARAIDELGM
Mvan_0901|M.vanbaalenii_PYR-1 AALQAYNDFLLDWSSIAP--DRLLSLALIPYWDVDAAVAEIERCAAAGHK
MMAR_0083|M.marinum_M SCNDELLAAAAEHVEYAG------AMIAVDLTDPARAVTEVRRTADAQAM
. : . : * *:
MAV_0481|M.avium_104 VGALIAGSYDG-----LFLDDERFDPILTAAEAVDFPIYVHPGLPEAPVS
MSMEG_4063|M.smegmatis_MC2_155 VGTLVMGTCAG-----TFLDDDRYEPVLSAAEEVDRPIYLHPGLPPASVS
Mflv_0351|M.gilvum_PYR-GCK VALIKPGPVNG-LRGWRSPALPEFDPFWRDVESAGLPIVLHASYP----P
TH_0554|M.thermoresistible__bu TFLVRPAPVPSRFGGSRSMGLPEFDPFWQEVVNAGIPVTMHASDS----G
MUL_3878|M.ulcerans_Agy99 MVHVRPAPVPG-VPRNRSLGHRSHDRVWARLAEANVPVAFHLGDS----G
MAB_0299|M.abscessus_ATCC_1997 YGASITTSVLG-----RSIADPIFDPLYAELNRRRAVLFVHPAGCG----
Mvan_0901|M.vanbaalenii_PYR-1 GLVSTGKPHEH---GYKLLADRYWDPMWAAAQDANLSISFHVGGGN---L
MMAR_0083|M.marinum_M AGVMIYVSPTS------RLDEEGLHEFYAELSARRLPLFLHPALEP----
. . . : .* .
MAV_0481|M.avium_104 QRYYAGSWPASVHMMFSGPA-------FGWHAEAGIHIVRLILSGALDRH
MSMEG_4063|M.smegmatis_MC2_155 NAYYAGNWPGAVQWVFAGPG-------FGWHAEAGIHTIRMILSGALDRH
Mflv_0351|M.gilvum_PYR-GCK LDDYVGKWEPPYTQNFMTQS--AFRWMVLGHREIADMITALICHGTLTRF
TH_0554|M.thermoresistible__bu YQKHLMEWEGGDEYLSFKPS--ALREVVMGHRAIEDTLAAMICHGALSRF
MUL_3878|M.ulcerans_Agy99 YLEIAGMWGGKETFEPFAAPPDPLDKILVDDRAIHDTMASLIVHGVFDRH
MAB_0299|M.abscessus_ATCC_1997 -AESSLITDHSLTWS------------IGAPIEDTVAIMHLIVAGVPSRY
Mvan_0901|M.vanbaalenii_PYR-1 SRHLNDERTSVEGWRATLAR-----LTTSFFLESGITLADLLMSGVLARY
MMAR_0083|M.marinum_M ------PIGGATDWSLDAS--------LSPPVVTSTAAARLMLSGRLDEH
:: * ..
MAV_0481|M.avium_104 PTLKLLSGHWG-ELAAFYLERLDETLGLLPTGLERA--------PSDYYR
MSMEG_4063|M.smegmatis_MC2_155 PNLKMLSGHWG-EFVAGWLDRLDEVFAWCHH-LDRP--------ISQYYR
Mflv_0351|M.gilvum_PYR-GCK PKLRIASVENGSSWIFPLFNDFEELAKKMPQNFGEH--------PLDVFR
TH_0554|M.thermoresistible__bu PDLKILCVENGSGWVRNLLEQLDTAYRIMPKEFDEH--------PVEVFK
MUL_3878|M.ulcerans_Agy99 PTLRVASIENGSEWVHRLAKRLKKLANQHPRSFPND--------PVDALR
MAB_0299|M.abscessus_ATCC_1997 PDMKIVTCHLGGALPMVLERAHRQVTEWEATQCPEA--------PRDAAR
Mvan_0901|M.vanbaalenii_PYR-1 PKLRFVSVESAVGWIPFLLESLDFHYKKYEPWLERPEFAGNDMLPSDYFH
MMAR_0083|M.marinum_M PGLTLIIPHLG-GVLPYLAQRLIDQSGRGAALHDIP----------TYLR
* : . . . :
MAV_0481|M.avium_104 QQVWITPSGMYNQNQLNFMTAELGAQRIIYSEDFPYVV--RDNVSTFLEQ
MSMEG_4063|M.smegmatis_MC2_155 DHVWITPSGMFNQNRLKFILAELGHERIIYSEDYPYVE--SESVSEFLES
Mflv_0351|M.gilvum_PYR-GCK RNIWVSP---FWEGCVSDVVTTVGWDKVMFGSDYPHPEGLPEPKGFWKYA
TH_0554|M.thermoresistible__bu RNIYIHP---FLEDDVPGLIEIMGADHVLFGSDYPHPEGIGDPLSFVDRL
MUL_3878|M.ulcerans_Agy99 EHVWISP---YYEEDLTVLADRIGVDRILFGSDWPHGEGLESPLAFTLEL
MAB_0299|M.abscessus_ATCC_1997 R-LWYDTVGHDHTPALRAAVASLGVDRLIFGSDFPYQAGPRYVSSATYIE
Mvan_0901|M.vanbaalenii_PYR-1 RQVYANY---WYEDLQPWHVAAIGEDNLMFETDYPHQTCLDKEEIQHSIN
MMAR_0083|M.marinum_M TRTYVDTCS-FHPPALRCALDTIGPSRLVLGSDYPFRG-PVARAIADIAD
: :* ..:: *:*.
MAV_0481|M.avium_104 AGLS---EADTHAIAHTNAEALLRI------------------
MSMEG_4063|M.smegmatis_MC2_155 AELS---EDQRASIAHRNAQNLLHI------------------
Mflv_0351|M.gilvum_PYR-GCK EGMD---VRRTYDFMGDNARRFMGLPIANPDPEAARPPALSTA
TH_0554|M.thermoresistible__bu EGVS---EADKAKIMGGNAMGLLGIRVPA--------------
MUL_3878|M.ulcerans_Agy99 TGFS---RAAVQKIMRDNALDFLGVTVASVA------------
MAB_0299|M.abscessus_ATCC_1997 EGLS---AEDASAILDHNGAELLGLTGV---------------
Mvan_0901|M.vanbaalenii_PYR-1 EGLSGVSETTKEKILWRNAASLFNMDIAKLEKLT---------
MMAR_0083|M.marinum_M SGVD---ETFKESALIGNATAAIRTAAGAV-------------
.. *. :