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M. avium 104 MAV_2577 (-)

annotation: amidohydrolase family protein
coordinates: 2615831 - 2617060
length: 409

TQFTDAPIFDADQHMYETPDALTKYLPKEFQPKVQFVQIGRHTRIAILNKITDYMPNPTFERVAAPGAHE
KFYSGQNPEGLSMREMSGRGIDTPPGARNPEDRIAELDRQGVDACLNYPTLANLVEHSAAEDPDLTVAII
HALNQWMLEHWGFSHANRVYSTPVLTLGLVDEARRELEYILDNGAKVALIKPAPVNGYKGWRSPALPEFD
PFWRDVEDAGLPIVLHASQPPLQEYIDRWEPPSTSSAFEMSAFKWTALGHREIADMLTSLICHGTLTRFP
KLRIASVENGSAWIKPLFDDLQSTYGKMPQNFPEHPHDVFRRNIWVSPFWEGSVADVVQTVGWDKVMFGS
DWPHPEGLAEPKRYWQYAEGMDERRTYDFMGDNARRFMGLPIANPDPEAVKPPQLANA*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. avium 104MAV_2577--100% (409)amidohydrolase family protein
M. avium 104MAV_1851-0.091.42% (408) amidohydrolase family protein
M. avium 104MAV_1625-e-10144.70% (396) amidohydrolase family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97-----
M. gilvum PYR-GCKMflv_0351-0.073.22% (407) amidohydrolase 2
M. tuberculosis H37Rv-----
M. leprae Br4923-----
M. abscessus ATCC 19977-----
M. marinum MMMAR_3988-1e-10344.50% (391) metal-dependent hydrolase
M. smegmatis MC2 155MSMEG_2235-0.074.50% (404) amidohydrolase family protein
M. thermoresistible (build 8)TH_0554-1e-10744.70% (387) amidohydrolase family protein
M. ulcerans Agy99MUL_3849-1e-10143.99% (391) metal-dependent hydrolase
M. vanbaalenii PYR-1Mvan_0383-0.073.71% (407) amidohydrolase 2

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_0351|M.gilvum_PYR-GCK          MPEPAPQFRDAPIFDADQHMYETPDALTKFLPDRYTRAVQYGQFGRHTRI
Mvan_0383|M.vanbaalenii_PYR-1       MTESAEQFRDAPIFDADQHMYETPEALTKHLPQRYSRAVQFANFGRHTRI
MSMEG_2235|M.smegmatis_MC2_155      ---MTEQFTDAPIFDADQHMYETAEALTKFLPERYRRAVQYAQIGRHTRV
MAV_2577|M.avium_104                ----MTQFTDAPIFDADQHMYETPDALTKYLPKEFQPKVQFVQIGRHTRI
MMAR_3988|M.marinum_M               ---MPSRELPFPVFDADNHMYEPQEALTKFLPDKRRHVIDYVQVRGRTKI
MUL_3849|M.ulcerans_Agy99           ---MPSRELPFPVFDADNHMYEPQEALTKFLPDKRKHVIDYVQVRGRTKI
TH_0554|M.thermoresistible__bu      ---MSPRSLPYPVFDIDNHMYETTDALIKFLPREHRGKVGYVELNGRKKL
                                          :    *:** *:****. :** *.** .    : : :.  :.::

Mflv_0351|M.gilvum_PYR-GCK          VINNRVSDFIPNPTFERVAAPGAHEKFFAGENTEGLTLREMQGPAIEAPA
Mvan_0383|M.vanbaalenii_PYR-1       VINNRVSDFIPNPTFERVAAPGAHEKFFAGENTEGLTLREMQGPAIEAPA
MSMEG_2235|M.smegmatis_MC2_155      VINNRVTDFIPNPTFERVAAPGAHEKFFAGENTEGLTLREMQGKPIEAPA
MAV_2577|M.avium_104                AILNKITDYMPNPTFERVAAPGAHEKFYSGQNPEGLSMREMSGRGIDTPP
MMAR_3988|M.marinum_M               VVRGQISDYIPNPTFEVVARPGAQEEYFR-NGSRGKSYREVMGEPMKAIP
MUL_3849|M.ulcerans_Agy99           VVRGQISDYIPNPTFEVVARPGAQEEHFR-NGSGGKSYREVMGEPMKAIP
TH_0554|M.thermoresistible__bu      MVKDRISHMIPNPTFEKVARPGSAEDYFLGNNPEGLNFREFVGEPMEVIP
                                     : .:::. :****** ** **: *..:  :.. * . **. *  :.. .

Mflv_0351|M.gilvum_PYR-GCK          ATRNPADRVAELDRQGVREALNYPTLASLIEHATADDPELTLAVIHALNQ
Mvan_0383|M.vanbaalenii_PYR-1       ATRNPADRVAELDRQGVREALNYPTLASLIEHATADDPELTLAVIHALNQ
MSMEG_2235|M.smegmatis_MC2_155      ATRNPEDRIAELDRQGVVEALIYPTLGSLVEHSSADDPQLTLAIIHALNE
MAV_2577|M.avium_104                GARNPEDRIAELDRQGVDACLNYPTLANLVEHSAAEDPDLTVAIIHALNQ
MMAR_3988|M.marinum_M               AFREPGPRLEVMDELGLDYALMFPTLASLVEERMKDDPEMTHDVIHALNQ
MUL_3849|M.ulcerans_Agy99           AFREPGPRLEVMDELGLDYALMFPTLASLVEERMKDDPEMTHDVIHALNQ
TH_0554|M.thermoresistible__bu      AFQHPAPRLELMDELGIDRCVMYPTLASLIEERTTDDVVLTHAVMHALNQ
                                    . :.*  *:  :*. *:  .: :***..*:*.   :*  :*  ::****:

Mflv_0351|M.gilvum_PYR-GCK          WMAEHWTFDYQGRVFSTPIINLSEVDGAQRELEYILTQGARVALIKPGPV
Mvan_0383|M.vanbaalenii_PYR-1       WMLEHWGFDYQGRVFSTPIINLSEVDGAQRELDYVLTHGAKVALIKPGPV
MSMEG_2235|M.smegmatis_MC2_155      WILEHWTFNHADRLFTTPIINLSEVEAAQRELAWILEHGAKAALIKPGPV
MAV_2577|M.avium_104                WMLEHWGFSHANRVYSTPVLTLGLVDEARRELEYILDNGAKVALIKPAPV
MMAR_3988|M.marinum_M               WMYETWSFNYKDRIFATPVITLPIVDRALEELEWCLQRGARTVLVRPAPV
MUL_3849|M.ulcerans_Agy99           WMYETWSFNYKDRIFATPVITLPIVDRALEELEWCLQRGARTVLVRPAPV
TH_0554|M.thermoresistible__bu      WMHEHWSFDYEGRIFATPVITLPIVEEAIRELHWCLERGMRTFLVRPAPV
                                    *: * * *.: .*:::**::.*  *: * .** : * .* :. *::*.**

Mflv_0351|M.gilvum_PYR-GCK          NG-LRGWRSPALPEFDPFWRDVESAGLPIVLHASYPPLDDYVGKWEPPYT
Mvan_0383|M.vanbaalenii_PYR-1       NG-LRGWRSPALPEFDPFWRDVEAAGLPIVLHASYPPLDDYVGKWEPPHT
MSMEG_2235|M.smegmatis_MC2_155      NG-LHGWRSPALPEFDPFWRDVEAAGLPIVLHASFPPLDDYINKWEPAHT
MAV_2577|M.avium_104                NG-YKGWRSPALPEFDPFWRDVEDAGLPIVLHASQPPLQEYIDRWEPPST
MMAR_3988|M.marinum_M               PG-YRGSRSFGFEEFDPFWQACIKAGIPVSMHASDSGYSEFLNVWEPGDE
MUL_3849|M.ulcerans_Agy99           PG-YRGSRSFGFKEFDPFWQACIKAGIPVSMHASDSGYSEFLNVWEPGDE
TH_0554|M.thermoresistible__bu      PSRFGGSRSMGLPEFDPFWQEVVNAGIPVTMHASDSGYQKHLMEWEGGDE
                                     .   * ** .: ******:    **:*: :*** .  ...:  **    

Mflv_0351|M.gilvum_PYR-GCK          QNFMTQSAFRWMVLGHREIADMITALICHGTLTRFPKLRIASVENGSSWI
Mvan_0383|M.vanbaalenii_PYR-1       QNFMAMSAFRWMVLGHREIADMITSLICHGTLTRFPKLRIASVENGSSWI
MSMEG_2235|M.smegmatis_MC2_155      QNFMTQSAFRWMVLGHREIADMLTALICHGTLTRFPRLRIASVENGSSWI
MAV_2577|M.avium_104                SSAFEMSAFKWTALGHREIADMLTSLICHGTLTRFPKLRIASVENGSAWI
MMAR_3988|M.marinum_M               FLPFKPTAFRMLAMGKRPIEDAMGALVCHGALSRNPELRILSIENGADWV
MUL_3849|M.ulcerans_Agy99           FLPFKPTAFRMLAMSKRPIEDAMGALVCHGALSRNPELRILSIKNGADWV
TH_0554|M.thermoresistible__bu      YLSFKPSALREVVMGHRAIEDTLAAMICHGALSRFPDLKILCVENGSGWV
                                       :  :*::  .:.:* * * : :::***:*:* * *:* .::**: *:

Mflv_0351|M.gilvum_PYR-GCK          FPLFNDFEELAKKMPQNFGEHPLDVFRRNIWVSPFWEGCVSDVVTTVGWD
Mvan_0383|M.vanbaalenii_PYR-1       FPLFNDFDELAKKMPQNFGEHPLDVFRRNIWVSPFWEGCVSDVVNTVGWD
MSMEG_2235|M.smegmatis_MC2_155      FPLFRDFADLYKKMPQNFPEHPHDVFRRNIWVSPFWEGCVADVVETVGWD
MAV_2577|M.avium_104                KPLFDDLQSTYGKMPQNFPEHPHDVFRRNIWVSPFWEGSVADVVQTVGWD
MMAR_3988|M.marinum_M               PTLFKGLKGVYKKMPNAFMEDPIEAFKRCVYISPFWEDRFAEIVKMVGTD
MUL_3849|M.ulcerans_Agy99           PTLFKGLKGVYKKMPNAFMEDPIEAFKRCVYISPFWEDRFVEIVKMVGTD
TH_0554|M.thermoresistible__bu      RNLLEQLDTAYRIMPKEFDEHPVEVFKRNIYIHPFLEDDVPGLIEIMGAD
                                      *:  :      **: * *.* :.*:* ::: ** *. .  ::  :* *

Mflv_0351|M.gilvum_PYR-GCK          KVMFGSDYPHPEGLPEPKGFWKYAEGMDVRRTYDFMGDNARRFMGLPIAN
Mvan_0383|M.vanbaalenii_PYR-1       KVMFGSDYPHPEGLAEPKGFWKYAEGMDVRRTYDFMGDNARRFMGLPIAN
MSMEG_2235|M.smegmatis_MC2_155      KVLFGSDYPHPEGLAEPKGFWKYAEGMDIRRTYDFMGDNARRFMGLPIAN
MAV_2577|M.avium_104                KVMFGSDWPHPEGLAEPKRYWQYAEGMDERRTYDFMGDNARRFMGLPIAN
MMAR_3988|M.marinum_M               RVVFGSDWPHPEGLKDPISFVDELAGFPPEDVAKIMGGNMMEVMKIGTPA
MUL_3849|M.ulcerans_Agy99           RVVFGSDWPHPEGLKDPISFVDELAGFPPEDVAKIMGGNMMDVMKIGTAA
TH_0554|M.thermoresistible__bu      HVLFGSDYPHPEGIGDPLSFVDRLEGVSEADKAKIMGGNAMGLLGIRVPA
                                    :*:****:*****: :*  : .   *.      .:**.*   .: :  . 

Mflv_0351|M.gilvum_PYR-GCK          PDPEAARPPALSTA-
Mvan_0383|M.vanbaalenii_PYR-1       PDPAAARPPALTTA-
MSMEG_2235|M.smegmatis_MC2_155      PDPDAVKPPALTASS
MAV_2577|M.avium_104                PDPEAVKPPQLANA-
MMAR_3988|M.marinum_M               PQPVNA---------
MUL_3849|M.ulcerans_Agy99           PKPVNA---------
TH_0554|M.thermoresistible__bu      ---------------