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RSPARYEGRTTADASWRAVSAAADVTLSGIAHGYTELRERAHRPVERSEVAGVAPVLVVELDAPLLVADV ADHASPRIWQAFVAGVSQGPSSTVHSGAQHCIEVRLTPLGLHRVSGLAMDAVSNRVVSLEELFGKKARYL PERLAAEPNWVRRFDLLDSVFMRAAAEGPEADAEVEFAWHRLNRTGGTAGIGEILNEIGWSRARLAQRFR SQVGLTPKAAARVLRFNRAMTLLNQPGHRSLSSIALACGYFDQAHFNRDFRVLAGCSPRQWAALRHEDLM GYRIPADGEHLYKTGVDGGPSVGTVL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_3701c | - | - | 100% (307) | AraC family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_4712 | - | 1e-17 | 31.36% (169) | putative transcriptional regulator, AraC |
| M. abscessus ATCC 19977 | MAB_0738 | - | 2e-05 | 29.09% (110) | AraC family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_2241 | - | 3e-06 | 29.79% (94) | helix-turn-helix domain-containing protein |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | MAV_0221 | - | 1e-17 | 33.33% (198) | transcriptional regulator, AraC family protein |
| M. smegmatis MC2 155 | MSMEG_5911 | - | 9e-09 | 35.16% (91) | AraC family protein transcriptional regulator |
| M. thermoresistible (build 8) | TH_2588 | - | 8e-30 | 35.35% (198) | PUTATIVE putative transcriptional regulator, AraC family |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_4454 | - | 1e-06 | 26.23% (122) | helix-turn-helix domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2241|M.gilvum_PYR-GCK ------------MAAWKNTTAGAPLRGVVGRPAGASAFDLRRWAADGRTS
Mvan_4454|M.vanbaalenii_PYR-1 ------------MGAWKNATAGEPLRGVVGRPASSSVFDLRRWAADGRTG
MAV_0221|M.avium_104 --------------MYRPSPPLAEHIEYFGYWRGDEALGVHTSRALPRG-
TH_2588|M.thermoresistible__bu -----------VRDPARIEIGGHPAAPLRPFVTGYTGFDLRGFEPGVHVG
MAB_3701c|M.abscessus_ATCC_199 MRSPARYEGRTTADASWRAVSAAADVTLSGIAHGYTELRERAHRPVERSE
MSMEG_5911|M.smegmatis_MC2_155 ----------------MALAAGRGAGVLRSLIRGSVRFVSYREQAPPPP-
. : .
Mflv_2241|M.gilvum_PYR-GCK RYVEHYWSVNWDLRGNDPFDSTVITFPAMHITHEWGQDAVRHGFSLPNTL
Mvan_4454|M.vanbaalenii_PYR-1 RYVEHFWSVAWDLRGRDPFDTSVITFPAMHITREWGEDGARHGFPLPNTL
MAV_0221|M.avium_104 -----AVTAIIDVGGRTDLG--------------FYASDARTPLTVPPAF
TH_2588|M.thermoresistible__bu -MPSHTLTAVLTFGEPLEID---------------VPSGLSGTSGRYPSM
MAB_3701c|M.abscessus_ATCC_199 -VAGVAPVLVVELDAPLLVA----------------DVADHASPRIWQAF
MSMEG_5911|M.smegmatis_MC2_155 --LRDLVECSWERSGPATPAR-------------VLPDGCMDLIRLDGRV
.
Mflv_2241|M.gilvum_PYR-GCK VHGVVEQVFRTTISEKGCVVGARFRPGGFTARFGGDASVRTGCVEPIGDL
Mvan_4454|M.vanbaalenii_PYR-1 VHGVVEQVFRTTISERGWVVGARFRPGGFTARFGGDASTMTGRIQPVDDL
MAV_0221|M.avium_104 AAGAGATAYVVRVAPAHTVMTIHFRPAGALAFLGSPLSDLEDALVGLEDL
TH_2588|M.thermoresistible__bu ASGLLAQSISIRHRGAQRGVKLSFTPLGARMVFGMPAGALANSVVPLSDV
MAB_3701c|M.abscessus_ATCC_199 VAGVSQGPSSTVHSGAQHCIEVRLTPLGLHRVSGLAMDAVSNRVVSLEEL
MSMEG_5911|M.smegmatis_MC2_155 VVAGPDTTAYLAAASPDPVRGLRFRPGALPRVLGVPAAELRDTRVDLHDL
. . : * . * . : ::
Mflv_2241|M.gilvum_PYR-GCK -------FGAAVALPDDVEDAAAELDTLIGGGGPP---DAVFD---ALSA
Mvan_4454|M.vanbaalenii_PYR-1 S----DVFGGPVLVPDDVDAAAAEFDRLIAHGAEP---DDTYR---ALAA
MAV_0221|M.avium_104 WGRDAALLREQLIDAGSPPRRVALLQAFLVRRMRR---NAVWPP--ARLA
TH_2588|M.thermoresistible__bu LADLWPELEDRLGAAATWPHRFRVLDDVLARAVARTMCAGMFDVRPEVAA
MAB_3701c|M.abscessus_ATCC_199 FGKKARYLPERLAAEPNWVRRFDLLDSVFMRAAAE---GPEADA--EVEF
MSMEG_5911|M.smegmatis_MC2_155 R---------TVPSCDSLETLALTLASDLAPPRSE---TAPWS----LAA
: : :
Mflv_2241|M.gilvum_PYR-GCK LVDRIRDDSGVHRVEQVMDLSPWSVRTTQRVFRRYVGVPVKWVLCRYRLQ
Mvan_4454|M.vanbaalenii_PYR-1 VVDRIRDDSGIHRVEQVMSHSPWSVRTTQRVFRRYVGVPVKWVLCRYRLQ
MAV_0221|M.avium_104 PVLRGADLDPSMRVSKAQELSGLSRKRFAALFRCEVGLSPKAYLRVLRLQ
TH_2588|M.thermoresistible__bu AWQRLVDSRGQVRVGDLAHDLGCSRRHLTARFREEFGLTPKTLARILRLE
MAB_3701c|M.abscessus_ATCC_199 AWHRLNRTGGTAGIGEILNEIGWSRARLAQRFRSQVGLTPKAAARVLRFN
MSMEG_5911|M.smegmatis_MC2_155 LRHVTRRFADGAAVDDVADDLGWSDRTLHRHCTSVYGYGPAMLRRVLRFR
: . * * *:.
Mflv_2241|M.gilvum_PYR-GCK NAALEIETDPGVDFADLAVRLGWYDQAHFINDFRSMLGSTPGEYAAT---
Mvan_4454|M.vanbaalenii_PYR-1 NAALEIETDPAVDFADLAVRLGWYDQAHFINDFRAMLGSTPGEYAAT---
MAV_0221|M.avium_104 AALRALDTPARG--ATIAADLGYFDQAHFVREFRAFTGATPTQYARR---
TH_2588|M.thermoresistible__bu QAVGLVAAAGAPAWAEVSAAAGYADQAHLVRDWRSFTGRTPSSWFDG---
MAB_3701c|M.abscessus_ATCC_199 RAMTLLNQPGHRSLSSIALACGYFDQAHFNRDFRVLAGCSPRQWAALRHE
MSMEG_5911|M.smegmatis_MC2_155 RAVRLLG--SGTGLSDVAAQSGYADQPHLHREVRALARVGVRELLGQVSS
* : : :: *: **.*: .: * : .
Mflv_2241|M.gilvum_PYR-GCK ---------------YGQGR---------
Mvan_4454|M.vanbaalenii_PYR-1 ---------------HGRRP---------
MAV_0221|M.avium_104 ---------------RSSMPGHVELAR--
TH_2588|M.thermoresistible__bu ---------------DVLVDGRPHG----
MAB_3701c|M.abscessus_ATCC_199 DLMGYRIPADGEHLYKTGVDGGPSVGTVL
MSMEG_5911|M.smegmatis_MC2_155 AAN-----------RSTDVPSGSSTVA--