For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. thermoresistible (build 8) TH_2588 (-)

aa seq not available

Operon Prediction Model: Genebank

Paralogs

species	id	gene	e-value	identity (len)	annotation
M. thermoresistible (build 8)	TH_2588	-	-	100% (281)	putative transcriptional regulator, AraC family protein
M. thermoresistible (build 8)	TH_1844	-	4e-05	25.64% (273)	putative transcriptional regulator

Closest Orthologs (e-value cutoff: 1e-4)

species	id	gene	e-value	identity (len)	annotation
M. bovis AF2122 / 97	-	-	-	-	-
M. gilvum PYR-GCK	Mflv_2241	-	2e-05	27.08% (192)	helix-turn-helix domain-containing protein
M. tuberculosis H37Rv	-	-	-	-	-
M. leprae Br4923	-	-	-	-	-
M. abscessus ATCC 19977	MAB_4712	-	9e-32	31.78% (258)	putative transcriptional regulator, AraC
M. marinum M	-	-	-	-	-
M. avium 104	MAV_2711	-	3e-31	34.66% (251)	transcriptional regulator, AraC family protein
M. smegmatis MC2 155	MSMEG_5465	-	8e-09	31.68% (101)	transcriptional regulator, AraC family protein
M. ulcerans Agy99	-	-	-	-	-
M. vanbaalenii PYR-1	Mvan_4454	-	2e-07	26.80% (250)	helix-turn-helix domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


MAB_4712|M.abscessus_ATCC_1997      MAGNEAPNWDFVVAPVRSVPGVASMVGYRARDIPDGIHLGMPS-ATLTFI
MAV_2711|M.avium_104                ------------------------MVGYRTLDVPEGVHRGMPS-SMLTFI
Mflv_2241|M.gilvum_PYR-GCK          -----MAAWKNTTAGAPLRGVVGRPAGASAFDLRRWAADGRTS-RYVEHY
Mvan_4454|M.vanbaalenii_PYR-1       -----MGAWKNATAGEPLRGVVGRPASSSVFDLRRWAADGRTG-RYVEHF
TH_2588|M.thermoresistible__bu      -VRDPARIEIGGHPAAPLRPFVTGYTGFDLRGFEPGVHVGMPS-HTLTAV
MSMEG_5465|M.smegmatis_MC2_155      -MASNMRTGAHFTPIGGAPGIERLQAGLRGEGFTPHRHDTYAIGMTLSGV
                                                             ..    ..        .    :   

MAB_4712|M.abscessus_ATCC_1997      VSLDDGVESADSAAALDDARPNPLVLGGLHTRAPHIRQRPGQAGIQLAVH
MAV_2711|M.avium_104                VSLDDGVEAADTATALPAARPTPLILGGLHLRASHVRQRRGQAGVQLAVH
Mflv_2241|M.gilvum_PYR-GCK          WSVNWDLRGNDPFDSTVITFPAMHITHEWGQDAVRHGFSLPNTLVHGVVE
Mvan_4454|M.vanbaalenii_PYR-1       WSVAWDLRGRDPFDTSVITFPAMHITREWGEDGARHGFPLPNTLVHGVVE
TH_2588|M.thermoresistible__bu      LTFGEPLEIDVPSGLSGTSGRYPSMASGLLAQSISIRHRGAQRGVKLSFT
MSMEG_5465|M.smegmatis_MC2_155      QTFSYRGTKRVCLPGQWHVLHPDELHDGVPGTDDGFAYRIVYVDPALVFE
                                     :.                     :                       . 

MAB_4712|M.abscessus_ATCC_1997      PLASRALFG---VPSAELPVTDFQG-----LEILGGAVAGLPER----TA
MAV_2711|M.avium_104                PLASRALFG---LPSAELPVAEYDA-----TAVLGRDIVDLHHR----VA
Mflv_2241|M.gilvum_PYR-GCK          QVFRTTISEKGCVVGARFRPGGFTARFGGDASVRTGCVEPIGDL---FGA
Mvan_4454|M.vanbaalenii_PYR-1       QVFRTTISERGWVVGARFRPGGFTARFGGDASTMTGRIQPVDDLSDVFGG
TH_2588|M.thermoresistible__bu      PLGARMVFG---MPAGALANSVVPL-----SDVLADLWPELEDR----LG
MSMEG_5465|M.smegmatis_MC2_155      SSDRRLPFVADPIVDGAKVPRALAR------YLQRDGTDDEDDD------
                                                :  .                          .       

MAB_4712|M.abscessus_ATCC_1997      RQRRWSDAFDTVATYLTESRRQRSVA---PVRSEVVQAWHLLERS-QGRI
MAV_2711|M.avium_104                EAHRWPDVFALVAQYLIDARRRRDGA---TVRPEVLHAWHLLQRS-RGLM
Mflv_2241|M.gilvum_PYR-GCK          AVALPDDVEDAAAELDTLIGGGGPPD---AVFDALSALVDRIRDD-SGVH
Mvan_4454|M.vanbaalenii_PYR-1       PVLVPDDVDAAAAEFDRLIAHGAEPD---DTYRALAAVVDRIRDD-SGIH
TH_2588|M.thermoresistible__bu      AAATWPHRFRVLDDVLARAVARTMCAGMFDVRPEVAAAWQRLVDS-RGQV
MSMEG_5465|M.smegmatis_MC2_155      --LAATDVVTVIADMLSAHSSAGRVVPQRLDRAAITRVRESLMDNPSRRY
                                          .                           :    . :  .     

MAB_4712|M.abscessus_ATCC_1997      TVSTLASRVGISSRYLTTLFQREVGRSPKTVAMLMRFQRATSLLALSARR
MAV_2711|M.avium_104                PVTALADAVGVTTRHLATLFRREVGHSPKTVAMLMRFQHATGRIAESARR
Mflv_2241|M.gilvum_PYR-GCK          RVEQVMDLSPWSVRTTQRVFRRYVGVPVKWVLCRYRLQNA----ALEIET
Mvan_4454|M.vanbaalenii_PYR-1       RVEQVMSHSPWSVRTTQRVFRRYVGVPVKWVLCRYRLQNA----ALEIET
TH_2588|M.thermoresistible__bu      RVGDLAHDLGCSRRHLTARFREEFGLTPKTLARILRLEQAVG----LVAA
MSMEG_5465|M.smegmatis_MC2_155      RAADVERIAGMDRWSVARQFRAAFGTSPSRFRTMRQLQLAR------SLI
                                     .  :              *:  .* . . .    ::: *          

MAB_4712|M.abscessus_ATCC_1997      -GRVDLAAIAAETGFSDQAHLTHEFVRFTGVPPRTWLAAEFRNIQDGGHS
MAV_2711|M.avium_104                HGRVDLARVAADTGYSDQAHLSREFVRFAGVPPQRWLAEEFRNIQDGGHL
Mflv_2241|M.gilvum_PYR-GCK          DPGVDFADLAVRLGWYDQAHFINDFRSMLGSTPGEYAATYGQGR------
Mvan_4454|M.vanbaalenii_PYR-1       DPAVDFADLAVRLGWYDQAHFINDFRAMLGSTPGEYAATHGRRP------
TH_2588|M.thermoresistible__bu      AGAPAWAEVSAAAGYADQAHLVRDWRSFTGRTPSSWFDGDVLVD---GRP
MSMEG_5465|M.smegmatis_MC2_155      VGGAALAEAAHAAGFADQAHFTRKFKAAYGLTPAAWSGAVRHKPPVTSST
                                          *  :   *: ****: ..:    * .*  :              

MAB_4712|M.abscessus_ATCC_1997      FGSECEHDYLDAQRVADP---
MAV_2711|M.avium_104                LGSQWEHDCFESDRLVDTASP
Mflv_2241|M.gilvum_PYR-GCK          ---------------------
Mvan_4454|M.vanbaalenii_PYR-1       ---------------------
TH_2588|M.thermoresistible__bu      HG-------------------
MSMEG_5465|M.smegmatis_MC2_155      DPLT-----------------