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MTLVDRLRGAVAGMPRRLVVGAAGAALLSGLIGAVGGSATAGAFSRPGLPVEYLQVPSAAMGRDIKVQFQ SGGANSPALYLLDGMRAQDDFNGWDINTPAFEWYNQSGISVAMPVGGQSSFYSDWYKPACGKAGCTTYKW ETFLTSELPQYLSAQKQVKPTGSGVVGLSMAGSSALILAAYHPDQFVYAGSLSALLDPSQGMGPSLIGLA MGDAGGYKAADMWGPKEDPAWARNDPSLQVGKLVANNTRIWVYCGNGKPSDLGGDNLPAKFLEGFVRTSN LKFQDAYNGAGGHNAVWNFDANGTHDWPYWGAQLQAMKPDLQSVLGATPGAGPATAAATNAGNGQGT
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_0214 | - | - | 100% (347) | antigen 85-A |
| M. avium 104 | MAV_2816 | - | e-156 | 80.13% (317) | antigen 85-B |
| M. avium 104 | MAV_5183 | - | e-131 | 66.27% (335) | antigen 85-C |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3834c | fbpA | 1e-171 | 82.54% (338) | secreted antigen 85-A FBPA (Mycolyl transferase 85A) |
| M. gilvum PYR-GCK | Mflv_1164 | - | 1e-136 | 67.05% (352) | putative esterase |
| M. tuberculosis H37Rv | Rv3804c | fbpA | 1e-171 | 82.54% (338) | secreted antigen 85-A FBPA (Mycolyl transferase 85A) |
| M. leprae Br4923 | MLBr_00097 | fbpA | 1e-160 | 80.06% (331) | antigen 85A, mycolytransferase |
| M. abscessus ATCC 19977 | MAB_0176 | - | 1e-110 | 59.88% (334) | antigen 85-A precursor |
| M. marinum M | MMAR_5368 | fbpA | 0.0 | 89.91% (337) | secreted antigen 85-A FbpA |
| M. smegmatis MC2 155 | MSMEG_6398 | - | 1e-138 | 70.15% (335) | antigen 85-A |
| M. thermoresistible (build 8) | TH_2078 | fbpA | 1e-130 | 66.87% (335) | SECRETED ANTIGEN 85-A FBPA (MYCOLYL TRANSFERASE 85A) |
| M. ulcerans Agy99 | MUL_4987 | fbpA | 1e-179 | 88.43% (337) | secreted antigen 85-A FbpA |
| M. vanbaalenii PYR-1 | Mvan_1902 | - | 1e-136 | 70.25% (326) | putative esterase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_5368|M.marinum_M MKLVDRFRGAVTGT-PRRLMVGAVGAALLSGLVGFVGG---SATASAFSR
MUL_4987|M.ulcerans_Agy99 MKLVDRFRGAATGT-SRRLMVGAVGAALLSGLVGFVGG---SATASAFSR
MAV_0214|M.avium_104 MTLVDRLRGAVAGM-PRRLVVGAAGAALLSGLIGAVGG---SATAGAFSR
Mb3834c|M.bovis_AF2122/97 MQLVDRVRGAVTGM-SRRLVVGAVGAALVSGLVGAVGG---TATAGAFSR
Rv3804c|M.tuberculosis_H37Rv MQLVDRVRGAVTGM-SRRLVVGAVGAALVSGLVGAVGG---TATAGAFSR
MLBr_00097|M.leprae_Br4923 MKFVDRFRGAVAGM-LRRLVVEAMGVALLSALIGVVG----SAPAEAFSR
Mflv_1164|M.gilvum_PYR-GCK MKFVGKLRAAAR-----RSTVVALAAIVLPGLISAVGG---SATAGAFSR
TH_2078|M.thermoresistible__bu MKLVAKLRGAARAL-PRRLTVAALAAALLPGLVGAFGG---SATAGAFSR
MSMEG_6398|M.smegmatis_MC2_155 MKFVGRMRGAAAGL-SRRLTVAVAAAAVLPGLVGVVGG---SATAGAWSR
Mvan_1902|M.vanbaalenii_PYR-1 MRLLDRIRGPWAR----RLGIAALAAVLLPGVVGLTGG---SATAGAFSR
MAB_0176|M.abscessus_ATCC_1997 MKLFSKMRGALARQSARRIAVAATAVAVLPGVAGIVGGTALTPVAGAFSR
* :. :.*.. * : . .. ::..: . * :. * *:**
MMAR_5368|M.marinum_M PGLPVEYLQVPSAAMGRNIKVQFQSGGANSPALYLLDGMRAQDDFSGWDI
MUL_4987|M.ulcerans_Agy99 PGLPVEYLQVPSVAMGRNIKVQFQSGGANSPALYLLDGMRAQDDFSGWDI
MAV_0214|M.avium_104 PGLPVEYLQVPSAAMGRDIKVQFQSGGANSPALYLLDGMRAQDDFNGWDI
Mb3834c|M.bovis_AF2122/97 PGLPVEYLQVPSPSMGRDIKVQFQSGGANSPALYLLDGLRAQDDFSGWDI
Rv3804c|M.tuberculosis_H37Rv PGLPVEYLQVPSPSMGRDIKVQFQSGGANSPALYLLDGLRAQDDFSGWDI
MLBr_00097|M.leprae_Br4923 PGLPVEYLQVPSPSMGRDIKVQFQNGGANSPALYLLDGLRAQDDFSGWDI
Mflv_1164|M.gilvum_PYR-GCK PGLPVEYLMVPSAGMGRDIKVQFQSGGPNAPGVYLLDGLRAQDDFNGWDI
TH_2078|M.thermoresistible__bu PGLPVEYLMVPSAAMGRDIKVQFQSGGEGSPGVYLLDGLRARDDFNGWDI
MSMEG_6398|M.smegmatis_MC2_155 PGLPVEYLEVPSAAMGRDIRVEFQSGGPGAPALYLLDGMRAREDQNGWDI
Mvan_1902|M.vanbaalenii_PYR-1 PGLPVEYLMVPSPSMGRDIKIQFQSGGPNSPALYLLDGLRAQDDFNGWDI
MAB_0176|M.abscessus_ATCC_1997 PGLPVEYLQVPSASMGREIKVQFQPGG--AKAVYLLDGLRARDDFSGWDI
******** *** .***:*:::** ** : .:*****:**::* .****
MMAR_5368|M.marinum_M NTPAFEWYYQSGISVAMPVGGQSSFYSDWYNPACG--KAGCTTYKWETFL
MUL_4987|M.ulcerans_Agy99 NTPAFEWYYQSGISVAMPVGGQSSFYSDWYNPACG--KAGCTTYKWETFL
MAV_0214|M.avium_104 NTPAFEWYNQSGISVAMPVGGQSSFYSDWYKPACG--KAGCTTYKWETFL
Mb3834c|M.bovis_AF2122/97 NTPAFEWYDQSGLSVVMPVGGQSSFYSDWYQPACG--KAGCQTYKWETFL
Rv3804c|M.tuberculosis_H37Rv NTPAFEWYDQSGLSVVMPVGGQSSFYSDWYQPACG--KAGCQTYKWETFL
MLBr_00097|M.leprae_Br4923 NTTAFEWYYQSGISVVMPVGGQSSFYSDWYSPACG--KAGCQTYKWETFL
Mflv_1164|M.gilvum_PYR-GCK NTPAFEWYLDSGLAVVMPVGGQSSFYSDWYSPACG--KAGCSTYKWETFL
TH_2078|M.thermoresistible__bu ETAAFEWYYESGLSVIMPVGGQSSFYSDWYSPACG--NNGCQTYKWETFL
MSMEG_6398|M.smegmatis_MC2_155 ELPTFEWFLNSGISVVMPVGGQSSFYSDWYKPACGSKDGGCKTYKWETFL
Mvan_1902|M.vanbaalenii_PYR-1 NTQAFEWYLDSGISVIMPVGGQSSFYSNWYKPACG--KSGCLTYNWETFL
MAB_0176|M.abscessus_ATCC_1997 ETTAFEDYYQSGISMVMPVGGQSSFYTDWYNPAKG--KDGVWTYKWETFT
: :** : :**::: **********::**.** * . * **:****
MMAR_5368|M.marinum_M TSELPQYLSANKGVKPTGSGVVGLSMAGSSALILAAYHPDQFVYSGSLSA
MUL_4987|M.ulcerans_Agy99 TSELPQYLSANKGVKPTGSGVVGLSMAGSSALILAAYHPDQFVYSGSLSA
MAV_0214|M.avium_104 TSELPQYLSAQKQVKPTGSGVVGLSMAGSSALILAAYHPDQFVYAGSLSA
Mb3834c|M.bovis_AF2122/97 TSELPGWLQANRHVKPTGSAVVGLSMAASSALTLAIYHPQQFVYAGAMSG
Rv3804c|M.tuberculosis_H37Rv TSELPGWLQANRHVKPTGSAVVGLSMAASSALTLAIYHPQQFVYAGAMSG
MLBr_00097|M.leprae_Br4923 TSELPQYLQSNKQIKPTGSAAVGLSMAGLSALTLAIYHPDQFIYVGSMSG
Mflv_1164|M.gilvum_PYR-GCK TQELPAYLAANKGVDPNRNAAIGLSMAGSAALTLAIYYPQQFQYAGSMSG
TH_2078|M.thermoresistible__bu TQELPAYLASNYGVDRNRNAAVGLSMAGSAALVLAIYYPQQFQYAASLSG
MSMEG_6398|M.smegmatis_MC2_155 TQELPAWLAANRDVKPTGSAVVGLSMAGSSALMLAARHPQQFIYAASLSG
Mvan_1902|M.vanbaalenii_PYR-1 TQELPGWLQANRDVKPTGSAAVGLSMAGGSSLVLAAHHPGQFVWAGSMSG
MAB_0176|M.abscessus_ATCC_1997 TQELPAYLAANKGISQTGNAVVGLSMGASAALTLSIYHPQLFVYAGALSG
*.*** :* :: :. . ...:****.. ::* *: :* * : .::*.
MMAR_5368|M.marinum_M LLDPSQGMGPSLIGLAMGDAGGYKASDMWGPKDDP--AWARNDPMLQVGK
MUL_4987|M.ulcerans_Agy99 LLDPSQGIGPSLIGLAMGDAGGYKASDMWGPKDDP--AWARNDPMLQVGK
MAV_0214|M.avium_104 LLDPSQGMGPSLIGLAMGDAGGYKAADMWGPKEDP--AWARNDPSLQVGK
Mb3834c|M.bovis_AF2122/97 LLDPSQAMGPTLIGLAMGDAGGYKASDMWGPKEDP--AWQRNDPLLNVGK
Rv3804c|M.tuberculosis_H37Rv LLDPSQAMGPTLIGLAMGDAGGYKASDMWGPKEDP--AWQRNDPLLNVGK
MLBr_00097|M.leprae_Br4923 LLDPSNAMGPSLIGLAMGDAGGYKAADMWGPSTDP--AWKRNDPTVNVGT
Mflv_1164|M.gilvum_PYR-GCK FLNLSEGWWPALVNISMGDAGGYDANDMWGRTEDPNSAWKRNDPMVNIGK
TH_2078|M.thermoresistible__bu FLNLSEGWWPMLVGLAMGDAGGYDPNDMWGRTEDPNSAWKRNDPMVNIDK
MSMEG_6398|M.smegmatis_MC2_155 TLNPSEGWWPMLIGISMGDAGGYKADDMWGSTNDPNNAWKANDPTENVAT
Mvan_1902|M.vanbaalenii_PYR-1 FLNPSEGWWPGLINISMGDAGGYKANDMWG-PAETDPAWQYNDPMVQIPR
MAB_0176|M.abscessus_ATCC_1997 FLNPSD--MKFQIGLAMGDAGGFSASDMWGPDSDP--AWQRNDPFLNIQK
*: *: :.::******:.. **** :. ** *** ::
MMAR_5368|M.marinum_M LVANNTRIWVYCGNGKPSDLG-----GDNLPAKFLEGFVRTSNMKFQAAY
MUL_4987|M.ulcerans_Agy99 LVANNTRIWVYCGNGKPSDLG-----GDNLPAKFLEGFVRTSNMKFQAAY
MAV_0214|M.avium_104 LVANNTRIWVYCGNGKPSDLG-----GDNLPAKFLEGFVRTSNLKFQDAY
Mb3834c|M.bovis_AF2122/97 LIANNTRVWVYCGNGKPSDLG-----GNNLPAKFLEGFVRTSNIKFQDAY
Rv3804c|M.tuberculosis_H37Rv LIANNTRVWVYCGNGKPSDLG-----GNNLPAKFLEGFVRTSNIKFQDAY
MLBr_00097|M.leprae_Br4923 LIANNTRIWMYCGNGKPTELG-----GNNLPAKLLEGLVRTSNIKFQDGY
Mflv_1164|M.gilvum_PYR-GCK LVANNTRIWVYCGDGKPAEVNGNVA-GNNLPAKFLEGLTIRTNRTFQEEY
TH_2078|M.thermoresistible__bu LVANNTRIWVFCGDGTPADIGAGVPEGDNFNAKFLESFTLRTNKTFQQEY
MSMEG_6398|M.smegmatis_MC2_155 IANNGTRIWVYCGNGKPGELG-----GTDLPAKFLEGFVCRTNSTFQEKY
Mvan_1902|M.vanbaalenii_PYR-1 LVANNSRIWVYCGNGQPNELG-----GGDLPATFLEGLTIRTNRTFQDNY
MAB_0176|M.abscessus_ATCC_1997 IIDNGTRLWIYCGTGDSTDLDATRNGFENFTGGFLEGMAIGSNKKFVEAY
: *.:*:*::** * . ::. :: . :**.:. :* .* *
MMAR_5368|M.marinum_M NAAGGHNAVWNFDDNGTHSWEYWGAQLNAMKPDLQHTLGATP--------
MUL_4987|M.ulcerans_Agy99 NAAGGHNAVWNFDDNGTHSWEYWGAQLNAMRPDLQHTLGATP--------
MAV_0214|M.avium_104 NGAGGHNAVWNFDANGTHDWPYWGAQLQAMKPDLQSVLGATPGAGPATAA
Mb3834c|M.bovis_AF2122/97 NAGGGHNGVFDFPDSGTHSWEYWGAQLNAMKPDLQRALGATPN-------
Rv3804c|M.tuberculosis_H37Rv NAGGGHNGVFDFPDSGTHSWEYWGAQLNAMKPDLQRALGATPN-------
MLBr_00097|M.leprae_Br4923 NAGGGHNAVFNFPDSGTHSWEYWGEQLNDMKPDLQQYLGATP--------
Mflv_1164|M.gilvum_PYR-GCK IAAGGKNGVFNFPANGTHDWPYWGQQLQQMKPDIQRVLGAVPQPSAPAAP
TH_2078|M.thermoresistible__bu IAAGGKNGVFNFPDAGTHSWGYWGQQLQQMKPDIQRVLGVS------AA-
MSMEG_6398|M.smegmatis_MC2_155 IEAGGKNGVFNFPQSGTHNWAYWGQQLQAMKPDLQRVLGATP-----TA-
Mvan_1902|M.vanbaalenii_PYR-1 IAAGGTNGVFNFPNNGTHNWAYWGRELQAMKPDLQAHLL-----------
MAB_0176|M.abscessus_ATCC_1997 TAAGGKNAHIEFPPGGIHNWTYWGQQLRAMKPDMVAYLQSH---------
.** *. :* * *.* *** :*. *:**: *
MMAR_5368|M.marinum_M --NTGDTQGA
MUL_4987|M.ulcerans_Agy99 --NTGDTQGA
MAV_0214|M.avium_104 ATNAGNGQGT
Mb3834c|M.bovis_AF2122/97 --TGPAPQGA
Rv3804c|M.tuberculosis_H37Rv --TGPAPQGA
MLBr_00097|M.leprae_Br4923 --------GA
Mflv_1164|M.gilvum_PYR-GCK VAAEAPGAGG
TH_2078|M.thermoresistible__bu ----------
MSMEG_6398|M.smegmatis_MC2_155 ----------
Mvan_1902|M.vanbaalenii_PYR-1 ----------
MAB_0176|M.abscessus_ATCC_1997 ----------