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VPRISASSVEEHREQVHRRVFQAFADLMSEQSFDAITMAKLATAAGIGRTAIYHHFADKEAVIVEFASHE TSRYLEGLRAALSDISDPAQRLSVYIRHQLEAGQQFHMGLGNQLYGTLSRDAAVAIREHVVAVEEVLLEI LRDGVAAGTFVVEDRAATISLIHACLAPRHLPIEAIQRFVLRALGATP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4772 | - | - | 100% (188) | putative regulatory protein TetR |
| M. abscessus ATCC 19977 | MAB_0599 | - | 2e-08 | 29.32% (133) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_2913 | - | 5e-08 | 25.14% (175) | TetR family regulatory protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1510c | - | 2e-07 | 31.11% (90) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_0142 | - | 2e-06 | 27.88% (165) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1474c | - | 2e-07 | 31.11% (90) | transcriptional regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_3853 | - | 2e-07 | 28.57% (126) | putative regulatory protein |
| M. avium 104 | MAV_1733 | - | 2e-07 | 28.30% (159) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_4718 | - | 8e-08 | 32.00% (75) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_4549 | - | 3e-10 | 31.05% (190) | PUTATIVE putative TetR-family protein transcriptional regulator |
| M. ulcerans Agy99 | MUL_3785 | - | 1e-07 | 28.57% (126) | putative regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_0360 | - | 4e-08 | 33.73% (83) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3853|M.marinum_M MAASAPDEQTATPNRRSQQKSDRRLQLLSAAERLFA-ERGFLAVRLEDIG
MUL_3785|M.ulcerans_Agy99 MAASAPDEQTATPNRRSQQKSDRRLQLLSAAERLFA-ERGFLAVRLEDIG
MSMEG_4718|M.smegmatis_MC2_155 ---------MSSVTRRSQAKSDRRSQLIAAAERLVA-ERGYLAVRLEDIG
Mb1510c|M.bovis_AF2122/97 -----------MPKVSEDHLAARRRQILDGARRCFA-EYGYDKATVRRLE
Rv1474c|M.tuberculosis_H37Rv -----------MPKVSEDHLAARRRQILDGARRCFA-EYGYDKATVRRLE
Mvan_0360|M.vanbaalenii_PYR-1 -----------MRTNARTRDPERKSRIMAAAADLVA-RKGFHAVSIAEIG
Mflv_0142|M.gilvum_PYR-GCK -----------MTRPLRADAARNRARVLEVAYDTFA-AEG-LTVPIDEIA
TH_4549|M.thermoresistible__bu ------------VDGLTEQQREQRERILRAAAEILA-EQGRDAVTTRNVS
MAB_4772|M.abscessus_ATCC_1997 -------MPRISASSVEEHREQVHRRVFQAFADLMS-EQSFDAITMAKLA
MAV_1733|M.avium_104 MPSVTRTPPGRRSPGREQRREQLERRLLDATERLMRDGASFTELSVDRLA
. ::: . . :
MMAR_3853|M.marinum_M AAAGISGPAIYRHFPNKESLLVELLVGISSRLLAGARQVTTNSNDAAAAL
MUL_3785|M.ulcerans_Agy99 AAAGISGPAIYRHFPNKESLLVELLVGISSRLLAGARQVTTNSNDAAAAL
MSMEG_4718|M.smegmatis_MC2_155 AAVGVSGPAIYRHFPNKEAMLVELLVGISTRLLDGAREVVETHDDPAKAL
Mb1510c|M.bovis_AF2122/97 QAIGMSRGAIFHHFRDKDALFFALAREDTERMAA------------VASR
Rv1474c|M.tuberculosis_H37Rv QAIGMSRGAIFHHFRDKDALFFALAREDTERMAA------------VASR
Mvan_0360|M.vanbaalenii_PYR-1 AAAGITGSGIYRHFESKSAVLVALFDRVIDELLRDEQEILNTTDDLGQAL
Mflv_0142|M.gilvum_PYR-GCK RRAGVGAGTVYRHFPTKEALVVAVAEDRVRRIAERAR--------TLLAV
TH_4549|M.thermoresistible__bu AAAGVQPPTIYRHFGDMRRLIDDAASLGMAEYLKAKRERALTDDPVHDLR
MAB_4772|M.abscessus_ATCC_1997 TAAGIGRTAIYHHFADKEAVIVEFASHETSRYLEGLR------AALSDIS
MAV_1733|M.avium_104 GAAGISRASFYIYFEDKGHLLRRLASRVFGELTDGARR--WWSVAGRHDP
*: .: :* :. .
MMAR_3853|M.marinum_M DGLIDFHLDFALGEPDLIRIQDR-------------------DLGHLPAA
MUL_3785|M.ulcerans_Agy99 DGLIDFHLDFALGEPDLIRIQDR-------------------DLGHLPAA
MSMEG_4718|M.smegmatis_MC2_155 DALVDFHLDFAFDESDLIRIQDR-------------------DLAHLPDT
Mb1510c|M.bovis_AF2122/97 EGLIGVMRDMLAAPDQFDWLATRL------------------EIARKLRN
Rv1474c|M.tuberculosis_H37Rv EGLIGVMRDMLAAPDQFDWLATRL------------------EIARKLRN
Mvan_0360|M.vanbaalenii_PYR-1 DLLIAGQVEFVVADRELAQVYYN-------------------EINNLPEE
Mflv_0142|M.gilvum_PYR-GCK EGPGQALFVFFRDMVRSAAVDHG--------------------LVDALMN
TH_4549|M.thermoresistible__bu DG-WDLHVEFGLRHPATYTVLYGDPRPDAKPRAVAEGDAILRSLMQRVAE
MAB_4772|M.abscessus_ATCC_1997 DPAQRLSVYIRHQLEAGQQFHMG--------------------LGNQLYG
MAV_1733|M.avium_104 DDVRAAMTRIIATYRRHQAVLVA---------------------LNEMSG
: : .
MMAR_3853|M.marinum_M AERQVRKAQRQYVEIWVGVLRQLDPGLAEADARLMAHAAFGLLNSTPHSM
MUL_3785|M.ulcerans_Agy99 AERQVRKAQRQYVEIWVGVLRQLDPGLAEADARLMAHAAFGLLNSTPHSM
MSMEG_4718|M.smegmatis_MC2_155 AKRQVRRAQRQYVEIWVSVLTRLRRDLPEEEARVMAHATFGLLNSTPHSV
Mb1510c|M.bovis_AF2122/97 DPDFSRGWAERSAELAAATTDRLRR--QKQANRVRDDVPSDVLRCYLDLV
Rv1474c|M.tuberculosis_H37Rv DPDFSRGWAERSAELAAATTDRLRR--QKQANRVRDDVPSDVLRCYLDLV
Mvan_0360|M.vanbaalenii_PYR-1 DSRRLRRKQRLYLEEWVHLVNESRVDLTDAEARTVVHAVIGAIQSPLFHN
Mflv_0142|M.gilvum_PYR-GCK QGLDLEAVAPGVEAAFLSTLGDLLS-AAQGAGTVRPDVDVAVVKALLVVC
TH_4549|M.thermoresistible__bu AGRLRIGVDRAAEMMHSACRGVTLTLISQTPAERDPELSAATREAMLAAI
MAB_4772|M.abscessus_ATCC_1997 --TLSRDAAVAIREHVVAVEEVLLEILRDGVAAG--TFVVEDRAATISLI
MAV_1733|M.avium_104 YDPLTAQTYREILTGISGQLTRVIE-DGQADGSIRPRLAAATTASALTWM
. .
MMAR_3853|M.marinum_M KSADTKS-ACAPHSRAVMRAMTVAALTVDVGA------------------
MUL_3785|M.ulcerans_Agy99 ESADTKS-ACAPHSRAVMRAMTVAALTVDVGA------------------
MSMEG_4718|M.smegmatis_MC2_155 KPAVTKAQSSTAQSRGVLRRMTVAALTATG--------------------
Mb1510c|M.bovis_AF2122/97 LDGLLARLASGEDPQRLAAVLDLVENSVRRS-------------------
Rv1474c|M.tuberculosis_H37Rv LDGLLARLASGEDPQRLAAVLDLVENSVRRS-------------------
Mvan_0360|M.vanbaalenii_PYR-1 TG------LPEDRLRALLTDAARAVLGLDR--------------------
Mflv_0142|M.gilvum_PYR-GCK KVP---QVFDSEVTERVTRVIEDGLRPLR---------------------
TH_4549|M.thermoresistible__bu TTGGAAGPADGAGVATRAIALKSVLETGGAGVLTEAEAELLKEWLDRLSQ
MAB_4772|M.abscessus_ATCC_1997 HACLAPRHLPIEAIQRFVLRALGATP------------------------
MAV_1733|M.avium_104 VERACQQNLPAQPSAYDAELADTLAEIVWGALYLKPASGS----------