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VTEDLVNAALQAAHALGKDVADVPLVEVARAAGVSRSTLLRRLGGTRQALDAAVRETGVDPGGRAPVRER ATVAAAELIDERGLAAVTLEAVATQADCSVHSLYAAFGGRDELLRATFDRFGPIVDIEDTVGDSSVGTEE KLHRIYQRLVQAFSQKPRVMPAMYAEIMARPFDPSVRKLIEHNAPRMLGSVGLWLSGEIAAGRIRDLPVT VLTQQLLAPVVMHTALRPAAEGVLGLELPDIQEVCKIFADAFLHGVRVPEPPRG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4757 | - | - | 100% (264) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_1938c | - | 7e-06 | 28.69% (122) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_1638 | - | 1e-05 | 27.23% (191) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_4630 | - | 6e-06 | 29.25% (106) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_3144 | - | 7e-07 | 27.86% (140) | AcrR family transcriptional regulator |
| M. avium 104 | MAV_3805 | - | 8e-06 | 33.01% (103) | putative transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_4964 | - | 9e-73 | 52.69% (260) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_2600 | - | 1e-05 | 26.90% (145) | PUTATIVE putative transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_0145 | - | 9e-06 | 30.23% (86) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0313 | - | 5e-08 | 32.08% (106) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4630|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0313|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_3144|M.marinum_M -----------------------------------------MSPARVYGG
MAB_4757|M.abscessus_ATCC_1997 -----MTEDLVNAALQAAHALGKDVADVPLVEVARAAGVSRSTLLRRLGG
MSMEG_4964|M.smegmatis_MC2_155 MIAVAVPEELVDAALRAAAELGRGVADVPAEVIARHAGMSRSTLLRRLGG
TH_2600|M.thermoresistible__bu --------------------------------------------MSKPRV
MUL_0145|M.ulcerans_Agy99 ------------------------------------------MSTDSHGR
MAV_3805|M.avium_104 ------------------------------------------MGTQPAET
Mflv_4630|M.gilvum_PYR-GCK ----MSAEERHRNR--------RTRLIEAAMELIGTHGVAAATVTAVCAE
Mvan_0313|M.vanbaalenii_PYR-1 ----MSAEERHRNR--------RTRLIEAATELIGTRGVAAATVTAVCAE
MMAR_3144|M.marinum_M ----LSATQRDAQR--------RALLIDAAVALMGKQGAAACTVTAVCTE
MAB_4757|M.abscessus_ATCC_1997 TRQALDAAVRETGVDPGGRAPVRERATVAAAELIDERGLAAVTLEAVATQ
MSMEG_4964|M.smegmatis_MC2_155 SRSALDQAVRARGTDPGGLPPVRVRAVGAAAELIGEIGLGAVTLEAIADR
TH_2600|M.thermoresistible__bu RNRYSSGPTRGEQR--------RERLLQALEDLLASRPFAAIEVGDIARA
MUL_0145|M.ulcerans_Agy99 RWAKTDATQR--------------RILDAATEVFATRGFNAATMAEVVAS
MAV_3805|M.avium_104 PDDEDDVDPRRTRS--------RTRLLDAAANLLKTGGIEAVTIDAVTKA
. * * :: * : :
Mflv_4630|M.gilvum_PYR-GCK SGVTSRYFYQHFPDRDALLRAVYQQLYATFQEVIVDA--IPDAGAPPEVL
Mvan_0313|M.vanbaalenii_PYR-1 SGVTSRYFYQHFSGRDALLRAVYQQLYATFQEVIVDA--IPDAGEPPEVL
MMAR_3144|M.marinum_M SGVTSRYFYQQFRDRDALLRAMFTKISTTFQAVITKA--IPDDTVAPQEL
MAB_4757|M.abscessus_ATCC_1997 ADCSVHSLYAAFGGRDELLRATFDRFGP--IVDIEDT--VGDSSVGTEEK
MSMEG_4964|M.smegmatis_MC2_155 AECSVPSLHAVFGTRDGLLREVFEQYSP--VRDVEAF--LLEDHGDLRDT
TH_2600|M.thermoresistible__bu AGLSRSAFYFYFPSKAAAVGAMLGDVFGEISDVLDKWTELGDSVAARRRE
MUL_0145|M.ulcerans_Agy99 SGASIGSIYHHFGGKTELFLAIFEQMASAVEGKIEEALQQAGDETDRRRI
MAV_3805|M.avium_104 SKVARTTLYRHFNSSSQLLAATFERLLPQVIPPAPTSGTLRERLIELLSR
: : :: * .
Mflv_4630|M.gilvum_PYR-GCK AYAPIRGLVSMINNDPRLGRILFVESATEPLLRELRSDMMTGFTDLVLRE
Mvan_0313|M.vanbaalenii_PYR-1 AYAPIRRLVSMIDNDPRLGRILFVESATEPLLRELRSELMAGFTDLVLRE
MMAR_3144|M.marinum_M AYAPIKALVQMIENDPSMARILFVESGAEPLLRQLRSELMSEFAELVLRE
MAB_4757|M.abscessus_ATCC_1997 LHRIYQRLVQAFSQKPRVMPAMYAEIMARPFDPSVR-KLIEHNAPRMLGS
MSMEG_4964|M.smegmatis_MC2_155 VRAFYGMLTRALDRPPRVVPAIFSEALARPQSPAVQ-AVVGHGAPRMLGL
TH_2600|M.thermoresistible__bu VYDSFERVVAIWRQHAPLMAAMFDAASTD---AEVR-AMFEGHIDSFVDG
MUL_0145|M.ulcerans_Agy99 FELGVRAYLDGLWEHRRVARLLASGDRPTDFGITRR--------DRMTSA
MAV_3805|M.avium_104 QADLFAEAPVQVTTLAWAALGPAETHEPNTVQHAGAGTLRMRVIEQYRRP
.
Mflv_4630|M.gilvum_PYR-GCK ARLHLDIADSAVGVAHLASTLGVGGLFE------VLRRWLDGELEFTTDE
Mvan_0313|M.vanbaalenii_PYR-1 ARLHLDIADSAVGVAHLASTLGVGGLFE------VLRRRLDGELEFTTDE
MMAR_3144|M.marinum_M ARLHLDIPSEVIQVADLAATYGVGGLFE------ILRRWIDGQLNLSTEV
MAB_4757|M.abscessus_ATCC_1997 VGLWLSGEIAAGRIRDLPVTVLTQQLLAPVVMHTALRPAAEGVLGLELPD
MSMEG_4964|M.smegmatis_MC2_155 LAEWLTGEVAAGRVRDLPVLLLAQQLMAPMLMHLFVRPTSANLAFVGLPD
TH_2600|M.thermoresistible__bu SAARIRHERAVGEAPDGPDPEALARVLVG----MNVKALERDMRAITSGA
MUL_0145|M.ulcerans_Agy99 FRSWMAVLELDSSLHG--------QFLSR----ALLRSWRSRH-------
MAV_3805|M.avium_104 FDEILYSPESVDQLGELDIELALCQLVGP-----LVFARMTGLRVITHQD
: .. :
Mflv_4630|M.gilvum_PYR-GCK LVQHCAGFLGSLGSYVLLQNAVESAT-------TKAKPQS
Mvan_0313|M.vanbaalenii_PYR-1 LVQHCAGFLGSLGNYVLLQNTDQSAT-------TEARPHR
MMAR_3144|M.marinum_M LIEHCAGFLGSLGLYTLGQKPDPAASHIQVDINSPAGHNR
MAB_4757|M.abscessus_ATCC_1997 IQEVCKIFADAFLHGVRVPEPPRG----------------
MSMEG_4964|M.smegmatis_MC2_155 IDSACDVFADTFVRAVTTGESE------------------
TH_2600|M.thermoresistible__bu PADADLPRVLAFVWGRVLYDA-------------------
MUL_0145|M.ulcerans_Agy99 ----------------------------------------
MAV_3805|M.avium_104 CTRIVEGFIAAQTGDQPAWVEASSPNQ-------------