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VVPPDLVGFAEEAGLAAVACGPDVRVWQDVNRDFWSRFLRNFWRNFWRIRDLKELLREDWRFLTQCWQEV SSTLRSQAKDADLLFTGVLGEESAGNVAEFYGLPFATLHVFPIRANGQLVPGMPARVGRSIMKLSEWLGW PLFKKLEDPQRRELGLPKATKPSPWRITERGSLEIQAYDEACMPGLAAEWAEFGGLRPFVGALTLDLPTA SDDEVAAWIAAGAPPICFGFGSMPVESADRTLAMISAACDQLGERALLCAGGSDFSQVRHVENVKVVAAM NYSTIFPACKAVVHHGGAGTTAASLRAGVPTLVLSTDLDQTLWGARVKRLKVGTARRFSASTERTLVADL RSILDPQCVARAREVATRMTKPAESPVTAADLLENFARVRRAD*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4695c | - | - | 100% (394) | putative glycosyltransferase/rhamnosyltransferase |
| M. abscessus ATCC 19977 | MAB_4694c | - | e-145 | 64.43% (388) | glycosyltransferase |
| M. abscessus ATCC 19977 | MAB_4107c | - | e-131 | 57.29% (391) | glycosyltransferase GtfA |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1551 | - | 1e-114 | 53.30% (394) | glycosyltransferase |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. tuberculosis H37Rv | Rv1524 | - | 1e-114 | 53.30% (394) | glycosyltransferase |
| M. leprae Br4923 | MLBr_02348 | - | 1e-119 | 55.96% (386) | putative glycosyl transferase |
| M. marinum M | MMAR_2353 | - | 1e-111 | 51.55% (386) | UDP-glycosyltransferase |
| M. avium 104 | MAV_3265 | - | 1e-135 | 60.87% (391) | glycosyl transferase |
| M. smegmatis MC2 155 | MSMEG_0389 | - | 1e-134 | 58.82% (391) | glycosyl transferase |
| M. thermoresistible (build 8) | TH_1989 | - | 4e-45 | 62.41% (141) | Glycosyltransferase family protein 28 |
| M. ulcerans Agy99 | MUL_1529 | - | 1e-100 | 50.42% (359) | UDP-glycosyltransferase |
| M. vanbaalenii PYR-1 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1551|M.bovis_AF2122/97 MKFVVASYGTRGDIEPCAAVGLELQRRGHDVCLAVPPNLIGFVETAGLSA
Rv1524|M.tuberculosis_H37Rv MKFVVASYGTRGDIEPCAAVGLELQRRGHDVCLAVPPNLIGFVETAGLSA
MAV_3265|M.avium_104 MKCVLASYGTRGDIEPSVVVARELQRRGHDMIMAVPPDSVSFTEAAGLTA
MSMEG_0389|M.smegmatis_MC2_155 MKFVLASYGTRGDIEPSVVVGRELQSRGHTVLMAVPPDLIEFTEAANLRT
TH_1989|M.thermoresistible__bu --------------------------------------------------
MAB_4695c|M.abscessus_ATCC_199 --------------------------------MVVPPDLVGFAEEAGLAA
MMAR_2353|M.marinum_M MKFALAINGTRGDVEPCAALGRELSRRGHEVRVAVPPNLTGLAAAAGLEA
MUL_1529|M.ulcerans_Agy99 ----MSNRALHSGGNYRAEATKDAS--------QYPPNLTGVAAAAGLEA
MLBr_02348|M.leprae_Br4923 MKFTLAASGSRGDVEPFAALGLELQRRGHEVRIGVPPDMLRFVESAGLAA
Mb1551|M.bovis_AF2122/97 VAYGS-----RDSQEQLDEQFLH----NAWKLQNPIKLLREAMAPVTEGW
Rv1524|M.tuberculosis_H37Rv VAYGS-----RDSQEQLDEQFLH----NAWKLQNPIKLLREAMAPVTEGW
MAV_3265|M.avium_104 VPYGLDSQAWLDVYRNFWTSFFR----GFWKMGEMRGMWREMWDLSDQCW
MSMEG_0389|M.smegmatis_MC2_155 VAYGLDTKTWLDIYRNFWTFALH----RFWKAREIRSLWREMWDLSDECW
TH_1989|M.thermoresistible__bu --------------------------------------------------
MAB_4695c|M.abscessus_ATCC_199 VACGPDVRVWQDVNRDFWSRFLRNFWRNFWRIRDLKELLREDWRFLTQCW
MMAR_2353|M.marinum_M VPYGPDTDELLNDE----DNLQE-----FWKPQTSIKLVREGISDLRQAW
MUL_1529|M.ulcerans_Agy99 VPYCPDTDELLNDE----DNLQE-----FWKPQTSIKLVREGISDLRQAW
MLBr_02348|M.leprae_Br4923 VAYGPDTQEFLARDT--YSQWRQ-----WWKILPPIKALQQ----LRQAW
Mb1551|M.bovis_AF2122/97 AELSAMLTPVAAGADLLLTGQIYQEVVANVAEHHGIPLAALHFYPVRANG
Rv1524|M.tuberculosis_H37Rv AELSAMLTPVAAGADLLLTGQIYQEVVANVAEHHGIPLAALHFYPVRANG
MAV_3265|M.avium_104 AQMNTTLLSLADGADLLFAGQSYQEPAANVAEYYDLPLATLHHVPMRPNG
MSMEG_0389|M.smegmatis_MC2_155 AQMNATLRSVAADADVLFAGQSYQEPAANVAEFYDVPLVTLHHIPMRPNG
TH_1989|M.thermoresistible__bu --------------------------------------------------
MAB_4695c|M.abscessus_ATCC_199 QEVSSTLRSQAKDADLLFTGVLGEESAGNVAEFYGLPFATLHVFPIRANG
MMAR_2353|M.marinum_M SDMAGTLKTLADGADLVLTGMIHQGIALNAAEYYGIPLATMHFLPSRVNS
MUL_1529|M.ulcerans_Agy99 SDMAGTLKTLADGADLVLTGMIHQGIALNAAEYYGIPLATMHFLPSRVNS
MLBr_02348|M.leprae_Br4923 ADMATDLKSLADGADLVMTGVVYQGVVANVAEYYGIPFGVLHFVPARVNG
Mb1551|M.bovis_AF2122/97 EIAFPARLPAPLVRSTITAIDWLYWRMTKGVEDAQRRELGLPKASTPAPR
Rv1524|M.tuberculosis_H37Rv EIAFPARLPAPLVRSTITAIDWLYWRMTKGVEDAQRRELGLPKASTPAPR
MAV_3265|M.avium_104 QVVS--VLPAPLARSAMTAFDWFCWRLNKKVEDAQRRELGLPKATGPSPR
MSMEG_0389|M.smegmatis_MC2_155 RLVT--FLPPVLARASMTAFDWFAWRLNKKVEDAQRRDLGLPKATGPSTQ
TH_1989|M.thermoresistible__bu --------------------------------------------------
MAB_4695c|M.abscessus_ATCC_199 QLVP--GMPARVGRSIMKLSEWLGWPLFKKLEDPQRRELGLPKATKPSPW
MMAR_2353|M.marinum_M RVIP--ILSPRLNRSVISALWWVHWRVTKNPEEAQRRELGMAKASSSSTS
MUL_1529|M.ulcerans_Agy99 RVIP--ILSPRLNRSVISALWWVHWRVTKNPEEAQRRELGMAKASSSSTS
MLBr_02348|M.leprae_Br4923 KIIP--SLPSPLNRAILATVWRAHWLLAKKPEDAQRRELGLPKATSLSTR
Mb1551|M.bovis_AF2122/97 RMAVRGSLEIQAYDALCFPGLAAEWG---GRRPFVGALTMESATDADDEV
Rv1524|M.tuberculosis_H37Rv RMAVRGSLEIQAYDALCFPGLAAEWG---GRRPFVGALTMESATDADDEV
MAV_3265|M.avium_104 RIAERGSLEIQAYDEVCFPGLAEEWAKWDGQRPFVGTLTMELTTEADDEV
MSMEG_0389|M.smegmatis_MC2_155 RIADRMSLEVQAYDEVCFPGLAEEWAKWGELRPYVGTLTMELTTPADEEV
TH_1989|M.thermoresistible__bu --------------------------------------------------
MAB_4695c|M.abscessus_ATCC_199 RITERGSLEIQAYDEACMPGLAAEWAEFGGLRPFVGALTLDLPTASDDEV
MMAR_2353|M.marinum_M RILKGRSLEIQAYDELCFPGLAAEWAEWGDRRPFVGALTLEMPTESDNEV
MUL_1529|M.ulcerans_Agy99 RILKGRSLEIQAYDELCFPGLAAEWAEWGDRRPFVGALTLEMPTESDNEV
MLBr_02348|M.leprae_Br4923 RIVKRGALEIQAYDELCFPGLAAEWAEYGDRRPFVGALTLELPTAADNEV
Mb1551|M.bovis_AF2122/97 ASWIAADTPPIYFGFGSMPIGSLADRVAMISAACAELGERALICSGPSDA
Rv1524|M.tuberculosis_H37Rv ASWIAADTPPIYFGFGSMPIGSLADRVAMISAACAELGERALICSGPSDA
MAV_3265|M.avium_104 MSWIRGGTPPICFGFGSMPVESPADTVDMIGTACAQLGERALLCAGRSDF
MSMEG_0389|M.smegmatis_MC2_155 SSWICGGTPPICFGFGSMPVESPADTVAMISSVCAELGERALICAGWSDF
TH_1989|M.thermoresistible__bu ----------------------------MFASVCSRLGERALICAGGTDI
MAB_4695c|M.abscessus_ATCC_199 AAWIAAGAPPICFGFGSMPVESADRTLAMISAACDQLGERALLCAGGSDF
MMAR_2353|M.marinum_M LSWIASGTPPIYFGFGSMPVESPAATIAMISAACAELGERALICTGSNDL
MUL_1529|M.ulcerans_Agy99 LSWIASGTPPIYFGFGSMPVESPAATIAIISAACAELGERALICTGSNDL
MLBr_02348|M.leprae_Br4923 LSWIAAGTPPIYFGFGSMPIVSPTDTVAMIAAACADLGERALISVKPKDL
::.:.* ******:. .*
Mb1551|M.bovis_AF2122/97 TGIPQFDHVKVVRVVSHAAVFPTCRAVVHHGGAGTTAAGLRAGIPTLILW
Rv1524|M.tuberculosis_H37Rv TGIPQFDHVKVVRVVSHAAVFPTCRAVVHHGGAGTTAAGLRAGIPTLILW
MAV_3265|M.avium_104 SGVPAPDHVKVVGPVNYATIFPACRAVVHHGGSGTTAASLRAGVPTLILS
MSMEG_0389|M.smegmatis_MC2_155 SDVALADHVKVVGAVNYATVFPGCRAVVHHGGSGTTAASLRAGLPTLVLS
TH_1989|M.thermoresistible__bu DGVPEYGHVKVVGAVNYARVFPACRAIVHHGGSGTTAAVLRAGVPSLVTW
MAB_4695c|M.abscessus_ATCC_199 SQVRHVENVKVVAAMNYSTIFPACKAVVHHGGAGTTAASLRAGVPTLVLS
MMAR_2353|M.marinum_M GGLQAPENVKLVSGVSHAAVFPACRAVVHHGGAGTTAAGMRAGIPTLILW
MUL_1529|M.ulcerans_Agy99 GGLQAPENVKLVSGVSHAAVFPACCAVVHHGGAGTTAAGMRAGIPTLILW
MLBr_02348|M.leprae_Br4923 TQVPKFDHVKIVTSVSHAAVFPACRAVVHHGGAGTTAASLRAGVPTLILW
: :**:* :.:: :** * *:*****:***** :***:*:*:
Mb1551|M.bovis_AF2122/97 VTSDQPIWAAQIKQLKVGRGRRFSSATKESLIADLRTILAPDYVTRAREI
Rv1524|M.tuberculosis_H37Rv VTSDQPIWAAQIKQLKVGRGRRFSSATKESLIADLRTILAPDYVTRAREI
MAV_3265|M.avium_104 MDANQTIWGAQLKRLKVGATRRFSATDRDSLVQDLRKILAPDYARRAREI
MSMEG_0389|M.smegmatis_MC2_155 MDANQALWGAQIKRLKVGTTRRFSKTNRRTLIADLRTILDPAYAARAQAL
TH_1989|M.thermoresistible__bu SSADQPYWGNQVKRLKVGTSRRFSHTTPDTLVADLRRILTPDYAVRARAV
MAB_4695c|M.abscessus_ATCC_199 TDLDQTLWGARVKRLKVGTARRFSASTERTLVADLRSILDPQCVARAREV
MMAR_2353|M.marinum_M IWIEQPIWLAQIKRLKIGSGRRLASTTKETLVSDLRCILGPDYVARARTI
MUL_1529|M.ulcerans_Agy99 IWIEQPIWLAQIKRLKIGSGRRLASTTKETLVSDLRCILGPDYVARP---
MLBr_02348|M.leprae_Br4923 IFIEQPVWAAQIKRLKVGAGRRFSATTQRSLAADLRTILAPQYATRAREV
:*. * ::*:**:* **:: : :* *** ** * . *.
Mb1551|M.bovis_AF2122/97 ASRMTKPAASVTATADLLEDAARRAR--------
Rv1524|M.tuberculosis_H37Rv ASRMTKPAASVTATADLLEDAARRAR--------
MAV_3265|M.avium_104 AARMTKPADSVMKAADVVEDFVQSRSRTGRS---
MSMEG_0389|M.smegmatis_MC2_155 ARGMTRPAESVVRAADVIEAFARSRCSA------
TH_1989|M.thermoresistible__bu AARMTDPADSVVRAADLFETAVECAPGVAHRE--
MAB_4695c|M.abscessus_ATCC_199 ATRMTKPAESPVTAADLLENFARVRRAD------
MMAR_2353|M.marinum_M ANEMSKPGESATRAADLLENEVSVS---------
MUL_1529|M.ulcerans_Agy99 ------PG--LRRC--------------------
MLBr_02348|M.leprae_Br4923 ANRMSKPDESVNAAADLLEDKASRNKSRTRYQDC
*