For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
KFVLASYGTRGDIEPCAAVGRELIRRGHDVCMAVPPDLIGFVEAAGPTAVPYGPDLRNVLDAHREFWTHF FRNFWRVQELIEKRREVVEPFLLCWKDIVGTLTSLAEGADLLFTGVNFEDAAGNVAEYHDIPLATLHLFP LRSNGQFVPFLPARLGRSAMKAGEWLAWQNAKKVERVQREELRLPRATKPSPWRITERRALEIQAYDGMC FPGLATEWGGFSSNRPFVGALTLDLPTDFDEEVAGWIASGTPPIFFGFGSLPVESADQTFAMISAACAQL GERALVCSAGSGFGDAPDAENIKIVHAMNYSAAFPKCRAVVHHGGTGTTAAGLRAGAPTLILSTDLDQTL WGRRIKELKVGTTRRFSSTTVKTLTSDLRAILDPQCAARARELATHMTKPIESVTKTADLVEGLAASYRC GSRA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4694c | - | - | 100% (425) | glycosyltransferase |
| M. abscessus ATCC 19977 | MAB_4107c | - | e-145 | 60.28% (423) | glycosyltransferase GtfA |
| M. abscessus ATCC 19977 | MAB_4695c | - | e-145 | 64.43% (388) | putative glycosyltransferase/rhamnosyltransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1551 | - | 1e-131 | 56.40% (422) | glycosyltransferase |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. tuberculosis H37Rv | Rv1524 | - | 1e-131 | 56.40% (422) | glycosyltransferase |
| M. leprae Br4923 | MLBr_02348 | - | 1e-118 | 52.47% (425) | putative glycosyl transferase |
| M. marinum M | MMAR_2353 | - | 1e-125 | 54.24% (413) | UDP-glycosyltransferase |
| M. avium 104 | MAV_3265 | - | 1e-142 | 59.81% (418) | glycosyl transferase |
| M. smegmatis MC2 155 | MSMEG_0389 | - | 1e-137 | 56.97% (423) | glycosyl transferase |
| M. thermoresistible (build 8) | TH_1989 | - | 1e-40 | 53.19% (141) | Glycosyltransferase family protein 28 |
| M. ulcerans Agy99 | MUL_1529 | - | 1e-100 | 51.27% (355) | UDP-glycosyltransferase |
| M. vanbaalenii PYR-1 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1551|M.bovis_AF2122/97 MKFVVASYGTRGDIEPCAAVGLELQRRGHDVCLAVPPNLIGFVETAGLSA
Rv1524|M.tuberculosis_H37Rv MKFVVASYGTRGDIEPCAAVGLELQRRGHDVCLAVPPNLIGFVETAGLSA
MAV_3265|M.avium_104 MKCVLASYGTRGDIEPSVVVARELQRRGHDMIMAVPPDSVSFTEAAGLTA
MSMEG_0389|M.smegmatis_MC2_155 MKFVLASYGTRGDIEPSVVVGRELQSRGHTVLMAVPPDLIEFTEAANLRT
TH_1989|M.thermoresistible__bu --------------------------------------------------
MAB_4694c|M.abscessus_ATCC_199 MKFVLASYGTRGDIEPCAAVGRELIRRGHDVCMAVPPDLIGFVEAAGPTA
MMAR_2353|M.marinum_M MKFALAINGTRGDVEPCAALGRELSRRGHEVRVAVPPNLTGLAAAAGLEA
MUL_1529|M.ulcerans_Agy99 ----MSNRALHSGGNYRAEATKDAS--------QYPPNLTGVAAAAGLEA
MLBr_02348|M.leprae_Br4923 MKFTLAASGSRGDVEPFAALGLELQRRGHEVRIGVPPDMLRFVESAGLAA
Mb1551|M.bovis_AF2122/97 VAYGSR-----DSQEQLDEQFLHNAWKLQNPIKLLREAMAPVTEGWAELS
Rv1524|M.tuberculosis_H37Rv VAYGSR-----DSQEQLDEQFLHNAWKLQNPIKLLREAMAPVTEGWAELS
MAV_3265|M.avium_104 VPYGLDSQAWLDVYRNFWTSFFRGFWKMGEMRGMWREMWDLSDQCWAQMN
MSMEG_0389|M.smegmatis_MC2_155 VAYGLDTKTWLDIYRNFWTFALHRFWKAREIRSLWREMWDLSDECWAQMN
TH_1989|M.thermoresistible__bu --------------------------------------------------
MAB_4694c|M.abscessus_ATCC_199 VPYGPDLRNVLDAHREFWTHFFRNFWRVQELIEKRREVVEPFLLCWKDIV
MMAR_2353|M.marinum_M VPYGPDTDELLNDE-----DNLQEFWKPQTSIKLVREGISDLRQAWSDMA
MUL_1529|M.ulcerans_Agy99 VPYCPDTDELLNDE-----DNLQEFWKPQTSIKLVREGISDLRQAWSDMA
MLBr_02348|M.leprae_Br4923 VAYGPDTQEFLARDT---YSQWRQWWKILPPIKALQQ----LRQAWADMA
Mb1551|M.bovis_AF2122/97 AMLTPVAAGADLLLTGQIYQEVVANVAEHHGIPLAALHFYPVRANGEIAF
Rv1524|M.tuberculosis_H37Rv AMLTPVAAGADLLLTGQIYQEVVANVAEHHGIPLAALHFYPVRANGEIAF
MAV_3265|M.avium_104 TTLLSLADGADLLFAGQSYQEPAANVAEYYDLPLATLHHVPMRPNGQVVS
MSMEG_0389|M.smegmatis_MC2_155 ATLRSVAADADVLFAGQSYQEPAANVAEFYDVPLVTLHHIPMRPNGRLVT
TH_1989|M.thermoresistible__bu --------------------------------------------------
MAB_4694c|M.abscessus_ATCC_199 GTLTSLAEGADLLFTGVNFEDAAGNVAEYHDIPLATLHLFPLRSNGQFVP
MMAR_2353|M.marinum_M GTLKTLADGADLVLTGMIHQGIALNAAEYYGIPLATMHFLPSRVNSRVIP
MUL_1529|M.ulcerans_Agy99 GTLKTLADGADLVLTGMIHQGIALNAAEYYGIPLATMHFLPSRVNSRVIP
MLBr_02348|M.leprae_Br4923 TDLKSLADGADLVMTGVVYQGVVANVAEYYGIPFGVLHFVPARVNGKIIP
Mb1551|M.bovis_AF2122/97 PARLPAPLVRSTITAIDWLYWRMTKGVEDAQRRELGLPKASTPAPRRMAV
Rv1524|M.tuberculosis_H37Rv PARLPAPLVRSTITAIDWLYWRMTKGVEDAQRRELGLPKASTPAPRRMAV
MAV_3265|M.avium_104 --VLPAPLARSAMTAFDWFCWRLNKKVEDAQRRELGLPKATGPSPRRIAE
MSMEG_0389|M.smegmatis_MC2_155 --FLPPVLARASMTAFDWFAWRLNKKVEDAQRRDLGLPKATGPSTQRIAD
TH_1989|M.thermoresistible__bu --------------------------------------------------
MAB_4694c|M.abscessus_ATCC_199 --FLPARLGRSAMKAGEWLAWQNAKKVERVQREELRLPRATKPSPWRITE
MMAR_2353|M.marinum_M --ILSPRLNRSVISALWWVHWRVTKNPEEAQRRELGMAKASSSSTSRILK
MUL_1529|M.ulcerans_Agy99 --ILSPRLNRSVISALWWVHWRVTKNPEEAQRRELGMAKASSSSTSRILK
MLBr_02348|M.leprae_Br4923 --SLPSPLNRAILATVWRAHWLLAKKPEDAQRRELGLPKATSLSTRRIVK
Mb1551|M.bovis_AF2122/97 RGSLEIQAYDALCFPGLAAEWG---GRRPFVGALTMESATDADDEVASWI
Rv1524|M.tuberculosis_H37Rv RGSLEIQAYDALCFPGLAAEWG---GRRPFVGALTMESATDADDEVASWI
MAV_3265|M.avium_104 RGSLEIQAYDEVCFPGLAEEWAKWDGQRPFVGTLTMELTTEADDEVMSWI
MSMEG_0389|M.smegmatis_MC2_155 RMSLEVQAYDEVCFPGLAEEWAKWGELRPYVGTLTMELTTPADEEVSSWI
TH_1989|M.thermoresistible__bu --------------------------------------------------
MAB_4694c|M.abscessus_ATCC_199 RRALEIQAYDGMCFPGLATEWGGFSSNRPFVGALTLDLPTDFDEEVAGWI
MMAR_2353|M.marinum_M GRSLEIQAYDELCFPGLAAEWAEWGDRRPFVGALTLEMPTESDNEVLSWI
MUL_1529|M.ulcerans_Agy99 GRSLEIQAYDELCFPGLAAEWAEWGDRRPFVGALTLEMPTESDNEVLSWI
MLBr_02348|M.leprae_Br4923 RGALEIQAYDELCFPGLAAEWAEYGDRRPFVGALTLELPTAADNEVLSWI
Mb1551|M.bovis_AF2122/97 AADTPPIYFGFGSMPIGSLADRVAMISAACAELGERALICSGPSDATGIP
Rv1524|M.tuberculosis_H37Rv AADTPPIYFGFGSMPIGSLADRVAMISAACAELGERALICSGPSDATGIP
MAV_3265|M.avium_104 RGGTPPICFGFGSMPVESPADTVDMIGTACAQLGERALLCAGRSDFSGVP
MSMEG_0389|M.smegmatis_MC2_155 CGGTPPICFGFGSMPVESPADTVAMISSVCAELGERALICAGWSDFSDVA
TH_1989|M.thermoresistible__bu ------------------------MFASVCSRLGERALICAGGTDIDGVP
MAB_4694c|M.abscessus_ATCC_199 ASGTPPIFFGFGSLPVESADQTFAMISAACAQLGERALVCSAGSGFGDAP
MMAR_2353|M.marinum_M ASGTPPIYFGFGSMPVESPAATIAMISAACAELGERALICTGSNDLGGLQ
MUL_1529|M.ulcerans_Agy99 ASGTPPIYFGFGSMPVESPAATIAIISAACAELGERALICTGSNDLGGLQ
MLBr_02348|M.leprae_Br4923 AAGTPPIYFGFGSMPIVSPTDTVAMIAAACADLGERALISVKPKDLTQVP
::.:.*: ******:. ..
Mb1551|M.bovis_AF2122/97 QFDHVKVVRVVSHAAVFPTCRAVVHHGGAGTTAAGLRAGIPTLILWVTSD
Rv1524|M.tuberculosis_H37Rv QFDHVKVVRVVSHAAVFPTCRAVVHHGGAGTTAAGLRAGIPTLILWVTSD
MAV_3265|M.avium_104 APDHVKVVGPVNYATIFPACRAVVHHGGSGTTAASLRAGVPTLILSMDAN
MSMEG_0389|M.smegmatis_MC2_155 LADHVKVVGAVNYATVFPGCRAVVHHGGSGTTAASLRAGLPTLVLSMDAN
TH_1989|M.thermoresistible__bu EYGHVKVVGAVNYARVFPACRAIVHHGGSGTTAAVLRAGVPSLVTWSSAD
MAB_4694c|M.abscessus_ATCC_199 DAENIKIVHAMNYSAAFPKCRAVVHHGGTGTTAAGLRAGAPTLILSTDLD
MMAR_2353|M.marinum_M APENVKLVSGVSHAAVFPACRAVVHHGGAGTTAAGMRAGIPTLILWIWIE
MUL_1529|M.ulcerans_Agy99 APENVKLVSGVSHAAVFPACCAVVHHGGAGTTAAGMRAGIPTLILWIWIE
MLBr_02348|M.leprae_Br4923 KFDHVKIVTSVSHAAVFPACRAVVHHGGAGTTAASLRAGVPTLILWIFIE
::*:* :.:: ** * *:*****:***** :*** *:*: :
Mb1551|M.bovis_AF2122/97 QPIWAAQIKQLKVGRGRRFSSATKESLIADLRTILAPDYVTRAREIASRM
Rv1524|M.tuberculosis_H37Rv QPIWAAQIKQLKVGRGRRFSSATKESLIADLRTILAPDYVTRAREIASRM
MAV_3265|M.avium_104 QTIWGAQLKRLKVGATRRFSATDRDSLVQDLRKILAPDYARRAREIAARM
MSMEG_0389|M.smegmatis_MC2_155 QALWGAQIKRLKVGTTRRFSKTNRRTLIADLRTILDPAYAARAQALARGM
TH_1989|M.thermoresistible__bu QPYWGNQVKRLKVGTSRRFSHTTPDTLVADLRRILTPDYAVRARAVAARM
MAB_4694c|M.abscessus_ATCC_199 QTLWGRRIKELKVGTTRRFSSTTVKTLTSDLRAILDPQCAARARELATHM
MMAR_2353|M.marinum_M QPIWLAQIKRLKIGSGRRLASTTKETLVSDLRCILGPDYVARARTIANEM
MUL_1529|M.ulcerans_Agy99 QPIWLAQIKRLKIGSGRRLASTTKETLVSDLRCILGPDYVARP-------
MLBr_02348|M.leprae_Br4923 QPVWAAQIKRLKVGAGRRFSATTQRSLAADLRTILAPQYATRAREVANRM
*. * ::*.**:* **:: : :* *** ** * . *.
Mb1551|M.bovis_AF2122/97 TKPAASVTATADLLEDAARRAR--------
Rv1524|M.tuberculosis_H37Rv TKPAASVTATADLLEDAARRAR--------
MAV_3265|M.avium_104 TKPADSVMKAADVVEDFVQSRSRTGRS---
MSMEG_0389|M.smegmatis_MC2_155 TRPAESVVRAADVIEAFARSRCSA------
TH_1989|M.thermoresistible__bu TDPADSVVRAADLFETAVECAPGVAHRE--
MAB_4694c|M.abscessus_ATCC_199 TKPIESVTKTADLVEGLAASYRCGSRA---
MMAR_2353|M.marinum_M SKPGESATRAADLLENEVSVS---------
MUL_1529|M.ulcerans_Agy99 --PG--LRRC--------------------
MLBr_02348|M.leprae_Br4923 SKPDESVNAAADLLEDKASRNKSRTRYQDC
*