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VMTQRDPTTRRGLRAVSSGGDHYADWQSVYEDNAVWIYRTIYARVGNKPDAEDLTAEVFLAALRPLRLTV TKAEVRAYLRTTARTVLAAHWRETLGREITSIPDTQDIADQPPEADEPISTAPEHARAVLAALPENYRRI LELRFLQCCSIKESAARIGTTVANAKVLQHRALRLAAQINDQDAS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4652 | - | - | 100% (185) | putative RNA polymerase sigma factor |
| M. abscessus ATCC 19977 | MAB_3724c | - | 2e-05 | 29.33% (150) | RNA polymerase sigma factor SigD |
| M. abscessus ATCC 19977 | MAB_2163 | - | 4e-05 | 24.36% (156) | ECF subfamily RNA polymerase sigma factor |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1253 | sigE | 2e-07 | 25.50% (149) | RNA polymerase sigma factor SigE |
| M. gilvum PYR-GCK | Mflv_5063 | - | 4e-13 | 32.50% (160) | ECF subfamily RNA polymerase sigma-24 factor |
| M. tuberculosis H37Rv | Rv1221 | sigE | 2e-07 | 25.50% (149) | RNA polymerase sigma factor SigE |
| M. leprae Br4923 | MLBr_01076 | sigE | 2e-07 | 25.50% (149) | RNA polymerase sigma factor SigE |
| M. marinum M | MMAR_4216 | sigE | 7e-07 | 25.45% (165) | alternative RNA polymerase sigma factor SigE |
| M. avium 104 | MAV_4415 | - | 4e-64 | 68.51% (181) | RNA polymerase sigma factor, sigma-70 family protein |
| M. smegmatis MC2 155 | MSMEG_1418 | - | 3e-14 | 35.37% (147) | RNA polymerase ECF-type sigma factor |
| M. thermoresistible (build 8) | TH_1898 | - | 4e-13 | 33.11% (151) | RNA polymerase ECF-type sigma factor |
| M. ulcerans Agy99 | MUL_4519 | sigE | 5e-07 | 25.45% (165) | RNA polymerase sigma factor SigE |
| M. vanbaalenii PYR-1 | Mvan_1293 | - | 1e-13 | 33.33% (147) | ECF subfamily RNA polymerase sigma-24 factor |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4216|M.marinum_M ------MER-GGRGLGNTEWQLRVAAGDELP--MSDGREKPEEHTIT-TL
MUL_4519|M.ulcerans_Agy99 ------MER-GGRGLGNTAWQLRVAAGDELP--MSDGREKPEEHTIT-TL
Mb1253|M.bovis_AF2122/97 ------MELLGGPRVGNTESQLCVADGDDLPTYCSANSEDLNITTIT-TL
Rv1221|M.tuberculosis_H37Rv ------MELLGGPRVGNTESQLCVADGDDLPTYCSANSEDLNITTIT-TL
MLBr_01076|M.leprae_Br4923 MGDGIGMER-EGRWTGNTQCPLRVVPGDESP--TLDGRASPEDLIITNLL
MAB_4652|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_4415|M.avium_104 --------------------------------------------------
Mflv_5063|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1293|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_1418|M.smegmatis_MC2_155 --------------------------------------------------
TH_1898|M.thermoresistible__bu --------------------------------------------------
MMAR_4216|M.marinum_M STTTMSHPQLVRDDEWAETSDGLLGTAVFDATGDKAAMPSWDELVRQHAD
MUL_4519|M.ulcerans_Agy99 STTTMSHPQLVRDDEWAETSDGLLGTAVFDATGDKAAMPSWDELVRQHAD
Mb1253|M.bovis_AF2122/97 SPTSMSHPQQVRDDQWVEPSDQLQGTAVFDATGDKATMPSWDELVRQHAD
Rv1221|M.tuberculosis_H37Rv SPTSMSHPQQVRDDQWVEPSDQLQGTAVFDATGDKATMPSWDELVRQHAD
MLBr_01076|M.leprae_Br4923 SPTIMSHPPPSRDDDWVEPFDALQGTAVFDATGDKATMPSWEELVRQHAA
MAB_4652|M.abscessus_ATCC_1997 ---------------MMTQRDPTTRRGLRAVSSGGDHYADWQSVYEDNAV
MAV_4415|M.avium_104 ---------------MAARNEPVGPRPLRAVPEGG--YPDWEAVYSDNAA
Mflv_5063|M.gilvum_PYR-GCK -----------------MSADSEGAASEGAVPEGLDAPSALLALYDEALP
Mvan_1293|M.vanbaalenii_PYR-1 -----------------MSAE----------PDGEHAPRALLALYDEALP
MSMEG_1418|M.smegmatis_MC2_155 -----------------MSAET-------------DAPRALLRLYDEALP
TH_1898|M.thermoresistible__bu -----------------VSVE----------PDPQPAPQALLDLYDEALP
: : :
MMAR_4216|M.marinum_M RVYRLAYRLSGNQQDAEDLTQETFIRVFRSVQN-YQPGTFEGWLHRITTN
MUL_4519|M.ulcerans_Agy99 RVYRLAYRLSGNQQDAEDLTQETFIRVFRSVQN-YQPGTFEGWLHRITTN
Mb1253|M.bovis_AF2122/97 RVYRLAYRLSGNQHDAEDLTQETFIRVFRSVQN-YQPGTFEGWLHRITTN
Rv1221|M.tuberculosis_H37Rv RVYRLAYRLSGNQHDAEDLTQETFIRVFRSVQN-YQPGTFEGWLHRITTN
MLBr_01076|M.leprae_Br4923 RVYWLAYRLSGNQHDAEDLTQETFIRVFRSVQN-YQPGTFEGWLHRITTN
MAB_4652|M.abscessus_ATCC_1997 WIYRTIYARVGNKPDAEDLTAEVFLAALRPLRLTVTKAEVRAYLRTTART
MAV_4415|M.avium_104 WVYRTLFARVGNRADAEDLTAEVFLAALRPLRLTASAAEVRAYLRATART
Mflv_5063|M.gilvum_PYR-GCK AVYGYFVRRCGDRGTAEDLTSETFLAAMDAARKPSPPDLSVRWLIGVARH
Mvan_1293|M.vanbaalenii_PYR-1 AVYGYFVRRCGDRGTAEDLTSETFLAAMDAARKPSPPALTVPWLIGVARH
MSMEG_1418|M.smegmatis_MC2_155 VVYGYFVRRCGDRGTAEDLTSETFLAAMDAARKPSPPPMTVPWLIGVARH
TH_1898|M.thermoresistible__bu VVYGYFVRRCADRATAEDLTSETFLAAMDAAHRDAHTPISVPWLIGVARH
:* .:: ***** *.*: .: . : :* :
MMAR_4216|M.marinum_M LFLDMVRRRSRIRMEALPEDYDRVPADDPNPEQIYHDSRLGPDLQAALDS
MUL_4519|M.ulcerans_Agy99 LFLDMVRRRSRIRMEALPEDYDRVPADDPNPEQIYHDSRLGPDLQAALDS
Mb1253|M.bovis_AF2122/97 LFLDMVRRRARIRMEALPEDYDRVPADEPNPEQIYHDARLGPDLQAALAS
Rv1221|M.tuberculosis_H37Rv LFLDMVRRRARIRMEALPEDYDRVPADEPNPEQIYHDARLGPDLQAALAS
MLBr_01076|M.leprae_Br4923 LFLDMVRRRARIRMDALPDDYDRVPADEPNPEQIYHDSRLGPDLQAALDS
MAB_4652|M.abscessus_ATCC_1997 VLAAHWRETLGREITSIPDTQDIADQPPEADEPISTAP---EHARAVLAA
MAV_4415|M.avium_104 VLAAHWRETLGREITSIEDIE----QPPEHPDAISTAP---QRVARVLDS
Mflv_5063|M.gilvum_PYR-GCK KLADHYRRRWDRFATPVAELPE--PADPADEWDAELDR---IVAEQVLTR
Mvan_1293|M.vanbaalenii_PYR-1 KLADHYRRRHDRFTVPVADPPD--TAEPDDTWDAQLDR---IVAEQVLAR
MSMEG_1418|M.smegmatis_MC2_155 KLADHYRRRHDRFSVPVAELPE--PDDPADNWDAAVDR---IVAEAVLAR
TH_1898|M.thermoresistible__bu KLADHYRRRHHRQSVSVAEVPE--PDEPTDQWDAELDR---IVAESVLAR
: *. .: : .*
MMAR_4216|M.marinum_M LPPEFRAAVVLCDIEGLSYEEIGATLGVKLGTVRSRIHRGRQALRDY-LA
MUL_4519|M.ulcerans_Agy99 LPPEFRAAVVLCDIEGLSYEEIGATLGVKLGTVRSRIHRGRQALRDY-LA
Mb1253|M.bovis_AF2122/97 LPPEFRAAVVLCDIEGLSYEEIGATLGVKLGTVRSRIHRGRQALRDY-LA
Rv1221|M.tuberculosis_H37Rv LPPEFRAAVVLCDIEGLSYEEIGATLGVKLGTVRSRIHRGRQALRDY-LA
MLBr_01076|M.leprae_Br4923 LPPEFRAAVVLCDIEGLSYEEIGATLGVKLGTVRSRIHRGRQALRDYLLT
MAB_4652|M.abscessus_ATCC_1997 LPENYRRILELRFLQCCSIKESAARIGTTVANAKVLQHRALRLAAQINDQ
MAV_4415|M.avium_104 LPDRYRRILESRFLQGNSIKEAAAELGISVANAKVLQHRALRLAAQVNEG
Mflv_5063|M.gilvum_PYR-GCK LSDPHRAVLVLRYMDGCSVPECAELIGRTVHATEALLVRARRAFRAMYPE
Mvan_1293|M.vanbaalenii_PYR-1 LPAQHRAVLTLRYMDDCTVGECAELIGRTVHATEALLVRARRAFRAQYPR
MSMEG_1418|M.smegmatis_MC2_155 LPEQHRTVLALRYMDDCSVPECAELIGRTVHATEALLVRARKAFRAQYPR
TH_1898|M.thermoresistible__bu LPDQHRTVLALRYLDDCSVPECAHLIGRTVHATEALLVRARRAFRRAYPD
*. .* : :: : * . :* .: .. *. :
MMAR_4216|M.marinum_M AHPEHSELSPRLVGTAR
MUL_4519|M.ulcerans_Agy99 AHPEHSELSPRLVGTAR
Mb1253|M.bovis_AF2122/97 AHPEHGECAVHVN-PVR
Rv1221|M.tuberculosis_H37Rv AHPEHGECAVHVN-PVR
MLBr_01076|M.leprae_Br4923 AHPRDGATTDATHVKSA
MAB_4652|M.abscessus_ATCC_1997 ------DAS--------
MAV_4415|M.avium_104 ------GRP--------
Mflv_5063|M.gilvum_PYR-GCK ---PEGGLS--------
Mvan_1293|M.vanbaalenii_PYR-1 ---PEGGLP--------
MSMEG_1418|M.smegmatis_MC2_155 DSQSEGGAP--------
TH_1898|M.thermoresistible__bu ---REGGTS--------
.