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AARNEPVGPRPLRAVPEGGYPDWEAVYSDNAAWVYRTLFARVGNRADAEDLTAEVFLAALRPLRLTASAA EVRAYLRATARTVLAAHWRETLGREITSIEDIEQPPEHPDAISTAPQRVARVLDSLPDRYRRILESRFLQ GNSIKEAAAELGISVANAKVLQHRALRLAAQVNEGGRP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_4415 | - | - | 100% (179) | RNA polymerase sigma factor, sigma-70 family protein |
| M. avium 104 | MAV_4431 | - | 2e-09 | 27.56% (156) | RNA polymerase sigma factor SigL |
| M. avium 104 | MAV_1365 | - | 1e-08 | 28.67% (150) | RNA polymerase sigma-70 factor |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0756 | sigL | 8e-11 | 30.32% (155) | RNA polymerase sigma factor SigL |
| M. gilvum PYR-GCK | Mflv_5063 | - | 4e-13 | 32.91% (158) | ECF subfamily RNA polymerase sigma-24 factor |
| M. tuberculosis H37Rv | Rv0735 | sigL | 9e-11 | 30.32% (155) | RNA polymerase sigma factor SigL |
| M. leprae Br4923 | MLBr_01076 | sigE | 2e-08 | 28.00% (150) | RNA polymerase sigma factor SigE |
| M. abscessus ATCC 19977 | MAB_4652 | - | 3e-64 | 68.51% (181) | putative RNA polymerase sigma factor |
| M. marinum M | MMAR_1073 | sigL | 2e-08 | 27.56% (156) | alternative RNA polymerase sigma factor (RpoE), SigL |
| M. smegmatis MC2 155 | MSMEG_1418 | - | 2e-12 | 31.06% (161) | RNA polymerase ECF-type sigma factor |
| M. thermoresistible (build 8) | TH_1898 | - | 6e-14 | 33.33% (156) | RNA polymerase ECF-type sigma factor |
| M. ulcerans Agy99 | MUL_4519 | sigE | 2e-08 | 28.00% (150) | RNA polymerase sigma factor SigE |
| M. vanbaalenii PYR-1 | Mvan_1293 | - | 8e-12 | 31.45% (159) | ECF subfamily RNA polymerase sigma-24 factor |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0756|M.bovis_AF2122/97 --------------------------------------------------
Rv0735|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1073|M.marinum_M --------------------------------------------------
MAV_4415|M.avium_104 --------------------------------------------------
MAB_4652|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_5063|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1293|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_1418|M.smegmatis_MC2_155 --------------------------------------------------
TH_1898|M.thermoresistible__bu --------------------------------------------------
MLBr_01076|M.leprae_Br4923 MGDGIGMEREGRWTGNTQCPLRVVPGDESPTLDGRASPEDLIITNLLSPT
MUL_4519|M.ulcerans_Agy99 ------MERGGRGLGNTAWQLRVAAGDELPMSDGREKPEEHTIT-TLSTT
Mb0756|M.bovis_AF2122/97 -------------MARVSG----------AAAAEAALMRALYDEHAAVLW
Rv0735|M.tuberculosis_H37Rv -------------MARVSG----------AAAAEAALMRALYDEHAAVLW
MMAR_1073|M.marinum_M -------------MARVAG----------GGAAEAALMQALYDEHAAVLW
MAV_4415|M.avium_104 ------------MAARNEPVGPRPLRAVPEGG--YPDWEAVYSDNAAWVY
MAB_4652|M.abscessus_ATCC_1997 ------------MMTQRDPTTRRGLRAVSSGGDHYADWQSVYEDNAVWIY
Mflv_5063|M.gilvum_PYR-GCK --------------MSADSEGAASEGAVPEGLDAPSALLALYDEALPAVY
Mvan_1293|M.vanbaalenii_PYR-1 --------------MSAE----------PDGEHAPRALLALYDEALPAVY
MSMEG_1418|M.smegmatis_MC2_155 --------------MSAET-------------DAPRALLRLYDEALPVVY
TH_1898|M.thermoresistible__bu --------------VSVE----------PDPQPAPQALLDLYDEALPVVY
MLBr_01076|M.leprae_Br4923 IMSHPPPSRDDDWVEPFDALQGTAVFDATGDKATMPSWEELVRQHAARVY
MUL_4519|M.ulcerans_Agy99 TMSHPQLVRDDEWAETSDGLLGTAVFDATGDKAAMPSWDELVRQHADRVY
: : ::
Mb0756|M.bovis_AF2122/97 RYALRLTGDAAQAEDVVQETLLRAWQHPEVIGDTARPARAWLFTVARNMI
Rv0735|M.tuberculosis_H37Rv RYALRLTGDAAQAEDVVQETLLRAWQHPEVIGDTARPARAWLFTVARNMI
MMAR_1073|M.marinum_M RYAMRLTSDASYADDIVQETLLRAWQHPEVIDERGRSARAWLFTVARNMI
MAV_4415|M.avium_104 RTLFARVGNRADAEDLTAEVFLAALRPLRLTASAA-EVRAYLRATARTVL
MAB_4652|M.abscessus_ATCC_1997 RTIYARVGNKPDAEDLTAEVFLAALRPLRLTVTKA-EVRAYLRTTARTVL
Mflv_5063|M.gilvum_PYR-GCK GYFVRRCGDRGTAEDLTSETFLAAMDAARKPSPPD-LSVRWLIGVARHKL
Mvan_1293|M.vanbaalenii_PYR-1 GYFVRRCGDRGTAEDLTSETFLAAMDAARKPSPPA-LTVPWLIGVARHKL
MSMEG_1418|M.smegmatis_MC2_155 GYFVRRCGDRGTAEDLTSETFLAAMDAARKPSPPP-MTVPWLIGVARHKL
TH_1898|M.thermoresistible__bu GYFVRRCADRATAEDLTSETFLAAMDAAHRDAHTP-ISVPWLIGVARHKL
MLBr_01076|M.leprae_Br4923 WLAYRLSGNQHDAEDLTQETFIRVFRSVQNYQPGT--FEGWLHRITTNLF
MUL_4519|M.ulcerans_Agy99 RLAYRLSGNQQDAEDLTQETFIRVFRSVQNYQPGT--FEGWLHRITTNLF
.: *:*:. *.:: . . :* : :
Mb0756|M.bovis_AF2122/97 IDERRSARFRNVVGSTDQSGTPEQSTPDEVNAALDRLL---IADALAQLS
Rv0735|M.tuberculosis_H37Rv IDERRSARFRNVVGSTDQSGTPEQSTPDEVNAALDRLL---IADALAQLS
MMAR_1073|M.marinum_M IDDRRSARYRYVVSSTDADGAPEQSTPDEVGAALDRLL---IADALAQLS
MAV_4415|M.avium_104 AAHWRETLGREITSIEDIE----QPPEHPDAISTAPQR---VARVLDSLP
MAB_4652|M.abscessus_ATCC_1997 AAHWRETLGREITSIPDTQDIADQPPEADEPISTAPEH---ARAVLAALP
Mflv_5063|M.gilvum_PYR-GCK ADHYRRRWDRFATPVAELPE--PADPADEWDAELDRIV---AEQVLTRLS
Mvan_1293|M.vanbaalenii_PYR-1 ADHYRRRHDRFTVPVADPPD--TAEPDDTWDAQLDRIV---AEQVLARLP
MSMEG_1418|M.smegmatis_MC2_155 ADHYRRRHDRFSVPVAELPE--PDDPADNWDAAVDRIV---AEAVLARLP
TH_1898|M.thermoresistible__bu ADHYRRRHHRQSVSVAEVPE--PDEPTDQWDAELDRIV---AESVLARLP
MLBr_01076|M.leprae_Br4923 LDMVRRRARIRMDALPDDYDRVPADEPNPEQIYHDSRLGPDLQAALDSLP
MUL_4519|M.ulcerans_Agy99 LDMVRRRSRIRMEALPEDYDRVPADDPNPEQIYHDSRLGPDLQAALDSLP
* : .* *.
Mb0756|M.bovis_AF2122/97 AEHRAVIQRSYYRGWSTAQIATDLGIAEGTVKSRLHYAVRALRLTLQEL-
Rv0735|M.tuberculosis_H37Rv AEHRAVIQRSYYRGWSTAQIATDLGIAEGTVKSRLHYAVRALRLTLQEL-
MMAR_1073|M.marinum_M GEHRAVIERSYYRGWTTAQIAKDLEIAEGTVKSRLHYAVRALRLTLQEL-
MAV_4415|M.avium_104 DRYRRILESRFLQGNSIKEAAAELGISVANAKVLQHRALRLAAQVNEG--
MAB_4652|M.abscessus_ATCC_1997 ENYRRILELRFLQCCSIKESAARIGTTVANAKVLQHRALRLAAQINDQ--
Mflv_5063|M.gilvum_PYR-GCK DPHRAVLVLRYMDGCSVPECAELIGRTVHATEALLVRARRAFRAMYPE--
Mvan_1293|M.vanbaalenii_PYR-1 AQHRAVLTLRYMDDCTVGECAELIGRTVHATEALLVRARRAFRAQYPR--
MSMEG_1418|M.smegmatis_MC2_155 EQHRTVLALRYMDDCSVPECAELIGRTVHATEALLVRARKAFRAQYPRDS
TH_1898|M.thermoresistible__bu DQHRTVLALRYLDDCSVPECAHLIGRTVHATEALLVRARRAFRRAYPD--
MLBr_01076|M.leprae_Br4923 PEFRAAVVLCDIEGLSYEEIGATLGVKLGTVRSRIHRGRQALRDYLLTAH
MUL_4519|M.ulcerans_Agy99 PEFRAAVVLCDIEGLSYEEIGATLGVKLGTVRSRIHRGRQALRDY-LAAH
.* : : : . : .. . :
Mb0756|M.bovis_AF2122/97 ----GVTR--------
Rv0735|M.tuberculosis_H37Rv ----GVTR--------
MMAR_1073|M.marinum_M ----GVTR--------
MAV_4415|M.avium_104 ----GRP---------
MAB_4652|M.abscessus_ATCC_1997 ----DAS---------
Mflv_5063|M.gilvum_PYR-GCK -PEGGLS---------
Mvan_1293|M.vanbaalenii_PYR-1 -PEGGLP---------
MSMEG_1418|M.smegmatis_MC2_155 QSEGGAP---------
TH_1898|M.thermoresistible__bu -REGGTS---------
MLBr_01076|M.leprae_Br4923 PRDGATTDATHVKSA-
MUL_4519|M.ulcerans_Agy99 P-EHSELSPRLVGTAR