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QFGLDTFADVPAGMTNPEAIRAVVEEGVRADQVGVDIFAIGEHHRAEFVGESPETMLAAIAARTERITLA TAVTVLSTDDPVRVYQRFATLDGISNGRAELVLGRGSFTDSFPLFGYDLADYDELFNEKFDLMAKLLPGA PVTWSGTLRSALDNVEVYPKTAEGLRAWVGVGGSPESVVRSVRYRIPMILAIIGGNPMRFEPYVDLYRRA QRELGVTEPMPLGIHSPGHIAESDEEAIAQYWPGFRELRTTIGRERGWPAPRYEDYLAEVKAGSLYVGSP DTVAVKMAKTIRGLGADRFSLVYQAAQPGLGMQNVELYGTEVIPRVRELLAGDAVGAA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_3232c | - | - | 100% (339) | putative luciferase-like oxidoreductase |
| M. abscessus ATCC 19977 | MAB_4628c | - | 7e-37 | 31.78% (321) | luciferase-like monooxygenase |
| M. abscessus ATCC 19977 | MAB_0527c | - | 3e-10 | 23.75% (341) | monooxygenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1886c | - | 1e-07 | 23.12% (173) | oxidoreductase |
| M. gilvum PYR-GCK | Mflv_2404 | - | 3e-13 | 25.45% (330) | luciferase family protein |
| M. tuberculosis H37Rv | Rv3618 | - | 2e-12 | 23.46% (358) | monooxygenase |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_2824 | - | 5e-16 | 25.99% (327) | monooxygenase |
| M. avium 104 | MAV_0538 | - | 2e-13 | 23.23% (353) | limonene 1,2-monooxygenase |
| M. smegmatis MC2 155 | MSMEG_4092 | - | 6e-17 | 43.20% (125) | alkanal monooxygenase |
| M. thermoresistible (build 8) | TH_3390 | - | 3e-19 | 28.16% (309) | PUTATIVE luciferase family protein |
| M. ulcerans Agy99 | MUL_2949 | - | 2e-16 | 25.99% (327) | monooxygenase |
| M. vanbaalenii PYR-1 | Mvan_4242 | - | 9e-15 | 26.36% (330) | luciferase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Rv3618|M.tuberculosis_H37Rv -------------MKAPLRFGVFITPFHPTGQSPTVALQYDMERVVALDR
MAV_0538|M.avium_104 -------------MSAPLRFGVFITPFHPVGQSPTVALEYDLERVVALDR
TH_3390|M.thermoresistible__bu VTESTSADTSTDTSIYPKRFGVFQAPFHKFGIHPTVLFERDLQLIQRAEE
MMAR_2824|M.marinum_M --------------MANLRFGYFIAPFHRAGTNPTLALQRDLEFVEHLDA
MUL_2949|M.ulcerans_Agy99 --------------MAKLRFGYFIAPFHRAGTNPTLALQRDLEFVEHLDA
Mflv_2404|M.gilvum_PYR-GCK --------------MKISLFYEFPLPRPWSDDDEHQLFQHGLDEVELADK
Mvan_4242|M.vanbaalenii_PYR-1 --------------MKISLFYEFPLPRPWSEDDEHQLFQHGLDEVELADK
MAB_3232c|M.abscessus_ATCC_199 -----------------MQFGLDTFADVPAGMTNPEAIRAVVEEGVRADQ
MSMEG_4092|M.smegmatis_MC2_155 -MTRVATNRIGAGVEDGRPFRLGFLLHLDRDIPPAQAYREAVELFVAAEQ
Mb1886c|M.bovis_AF2122/97 ---------------MTIRLG-LQIPNFSYGTGVEKLFPSVIAQAREAEA
: : :
Rv3618|M.tuberculosis_H37Rv LGYDEAWFGEHHS-GGYELIACP---EVFIAAAAERTTHIRLGTGVVSLP
MAV_0538|M.avium_104 LGFDEAWFGEHHS-GGYELIACP---EVFIATAAERTKHIRLGTGVVSLP
TH_3390|M.thermoresistible__bu LGFHEAWIGEHHS-GGHEPIASP---EVFMAAASQRTHTIKLGTGVVSLP
MMAR_2824|M.marinum_M LGFDEAWIGEHHS-AGSEIISSP---EVFIAAAAERTKRIRLGTGVISLA
MUL_2949|M.ulcerans_Agy99 LGFDEAWIGEHHS-AGSEIISSP---EVFIAAAAERTKRIRLGTGVISLA
Mflv_2404|M.gilvum_PYR-GCK AGFSTVWLTEHHFLEEYCHSTAP---ELFLAAASQRTKNIRLGFGVMHLP
Mvan_4242|M.vanbaalenii_PYR-1 AGFSTVWLTEHHFLEEYCHSTAP---ELFLAAASQRTKNIRLGFGVMHLP
MAB_3232c|M.abscessus_ATCC_199 VGVDIFAIGEHHR--AEFVGESP---ETMLAAIAARTERITLATAVTVLS
MSMEG_4092|M.smegmatis_MC2_155 LGYDSGWVIHRHFRQGNEHVSAP---LVLLAAIAQHTSRIRLGTGVLVLA
Mb1886c|M.bovis_AF2122/97 AGYDSLFVMDHFYQLPMLGTPDQPMLEAYTALGALATATERLQLGALVTG
* . .:. * : * * ..
Rv3618|M.tuberculosis_H37Rv --YHHPLMVADRWVLLDHLTRGRVMFGTGPGALPSDAYMMGIDPVEQRRM
MAV_0538|M.avium_104 --YHHPLMVADRWVLLDHLTRGRVMFGTGPGALPSDAYMMGIDPVDQRHM
TH_3390|M.thermoresistible__bu --YHNPFMVAERHVLLDHLSRGRAIMGFGPGQLASDAHMMAVETAEQREM
MMAR_2824|M.marinum_M --YHNPLWVADRLMLLDHLTHGRVIGGMGPGSLPTDSAMIGLTPTDTREL
MUL_2949|M.ulcerans_Agy99 --YHNPLWVADRLMLLDHLTHGRVIGGMGPGSLATDSAMIGLTPTDTREL
Mflv_2404|M.gilvum_PYR-GCK PPINHPARIAERVATLDHLSNGRVEFGTGEGSSVAELGGFNIDPADKRAQ
Mvan_4242|M.vanbaalenii_PYR-1 PPINHPARIAERVATLDHLSNGRVEYGTGEGSSVAELGGFNIDPADKRTM
MAB_3232c|M.abscessus_ATCC_199 --TDDPVRVYQRFATLDGISNGRAELVLGRGSFTDSFPLFGYDLADYDEL
MSMEG_4092|M.smegmatis_MC2_155 --LEDPLKVAEDAATLDEISGGRLELGVGSGPFPSAWEAFGRDLNDRHRI
Mb1886c|M.bovis_AF2122/97 NTYRSPTLLAKIITTLDVVSAGRAILGIGAGWFELEHRQLGFEFGTFSDR
* : . ** :: ** * * :
Rv3618|M.tuberculosis_H37Rv MQESLEAILALFRAAPDERIDRHSDWFTLREAQLHIRPYTWPYPEIATAA
MAV_0538|M.avium_104 MQESLEAILALFRAAPTERIDRHSDWFTLRDAQLHIRPYTWPYPEISTAA
TH_3390|M.thermoresistible__bu MREAAEVIVRLMRG---ETVTAKTSWFELRDARLQVLPYNGAGLETVVAS
MMAR_2824|M.marinum_M LETNLDIVVRLLAG---QTVTAKTATHQLFDARLQLAPFSEGGIPLAVAA
MUL_2949|M.ulcerans_Agy99 LETNLDIVVRLLAG---QTVTAKTATHQLFDARLQLAPFSEGGIPLAVAA
Mflv_2404|M.gilvum_PYR-GCK WEEALEVSIRCMTEAP--FTGFKGEHVEMPARNVIPKPLQQPHPPVWVAC
Mvan_4242|M.vanbaalenii_PYR-1 WEEALEVSIRCMTEAP--FTGFKGEHVEMAARNVIPKPLQQPHPPVWVAC
MAB_3232c|M.abscessus_ATCC_199 FNEKFDLMAKLLPGAP----VTWSGTLRSALDNVEVYPKTAEGLRAWVGV
MSMEG_4092|M.smegmatis_MC2_155 FNDVVDRLHDVLDG---HVLNSVGETLHPPGAGVRRRLWQAITSDAVHSG
Mb1886c|M.bovis_AF2122/97 FNRLEEALQILEPMVKGERPTFFGDWYTTESAMAEPRYRDR--IPILIGG
. : .
Rv3618|M.tuberculosis_H37Rv MISPSGPRLAGALGTSLLSLSMSV-PGGYAALETAWGVVREQAAKAGRGE
MAV_0538|M.avium_104 MISPSGPRLAGALGTSLLSLSMSV-PGGYAALETTWDVVREQAAKAGRDE
TH_3390|M.thermoresistible__bu VASPSGPRTAGELGLGMINLASSG-PGAFEALRDHWSIVESEAAKSG-AE
MMAR_2824|M.marinum_M VASPTGARLAGRHGIGLLSIGATLTIEGFDALAYHWGIVEERAAAFG-TH
MUL_2949|M.ulcerans_Agy99 VASPTGARLAGRHGIGLLSIGATLTIEGFDALAYHWGIVEERAAAFG-TH
Mflv_2404|M.gilvum_PYR-GCK TR-PSSVGMAAEKAIGALSFAYTGPEALKDRVDGYYKDFEEKGTPIT-PA
Mvan_4242|M.vanbaalenii_PYR-1 TR-PSSVQMAAQKAIGALSFAYTGPEALKERVDGYYKEFEEQGAPIT-PA
MAB_3232c|M.abscessus_ATCC_199 GGSPESVVRSVRYRIPMILAIIGGNPMRFEPYVDLYRRAQR---ELGVTE
MSMEG_4092|M.smegmatis_MC2_155 PAAVRAATAGDGLQLSRATAWQGGSVEDAQIRQSEWIAAYRDAWADPASP
Mb1886c|M.bovis_AF2122/97 GGEKKTFAIAARFADHLN------IVAAVDELPRKMRALAARCDEAGRDR
.
Rv3618|M.tuberculosis_H37Rv PDRADWRVLS--IMHLSDSRDQAIDDCTYG----LPDFSRYFGAAGFVPL
MAV_0538|M.avium_104 PDRGDWRVLS--IMHIADSREQAIDDCTYG----LQDFANYFGAAGFVPL
TH_3390|M.thermoresistible__bu VSRDQWRLAA--IMHIAETEEQARRDCEYG----FAEIWDYLGQISPLPP
MMAR_2824|M.marinum_M ADRKNWTLVG--PFHIAETDTQARADVKFG----IEPWFRYFQKVAAFPQ
MUL_2949|M.ulcerans_Agy99 ADRKNWTLVG--PFHIAETDAQARADVKFG----IEPWFRYFQKVAAFPQ
Mflv_2404|M.gilvum_PYR-GCK INPNLLAIGGDLSMMVAKTDEEALKRLGIGGGFFSFGIMHYYLTGMHTPG
Mvan_4242|M.vanbaalenii_PYR-1 INPNILAIGGDLSMMVAKTDEEALERLGIGGGFFSFGIMHYYLTGMHTPG
MAB_3232c|M.abscessus_ATCC_199 PMPLGIHSPG----HIAESDEEAIAQYWPG----FRELRTTIGRERGWPA
MSMEG_4092|M.smegmatis_MC2_155 PRVQVSR-----AVYPHGDRAEALRLVTPG----VRRWQSWSTHGDPRQT
Mb1886c|M.bovis_AF2122/97 STLQTSLLLT---VMIDETLSPDAIPAEMS--------------------
.
Rv3618|M.tuberculosis_H37Rv AN--TVEGTQSSREFVEQYAAKGNCCIGTPDDAIAHIEDLLHRSGGFGTL
MAV_0538|M.avium_104 AN--SVEGTQTPHEFVAEYAAKGNCCIGTPEDAIAHIEDLLDRSGGFGTL
TH_3390|M.thermoresistible__bu SKETSVEGKLN------EAIESGMVCIGTPDTAIELIRKLAKQTGGFGVF
MMAR_2824|M.marinum_M MT---MPGEQLD-EMIDIINENGAGVIGTPQRARAQVQRLWDQSGGFGCM
MUL_2949|M.ulcerans_Agy99 MT---MPGEQLD-EMIDIINENGAGVIGTPERARAQVQRLWDQSGGFGCM
Mflv_2404|M.gilvum_PYR-GCK RTGVWELYEKAVKEDPTLAYGPGRGAIGSPETVREFLR--GYEASGVDEI
Mvan_4242|M.vanbaalenii_PYR-1 RTGVWELYEKAVKEDPTLAYGPGRGAIGSPDTVREFLR--GYEASGVDEI
MAB_3232c|M.abscessus_ATCC_199 PR----------YEDYLAEVKAGSLYVGSPDTVAVKMAKTIRGLG--ADR
MSMEG_4092|M.smegmatis_MC2_155 ET-------------VDEYLTADRALIGPGAELADELASDPALRHASDLL
Mb1886c|M.bovis_AF2122/97 ----------------------GRVVVGSPAQIADQIQAKVLDAGVDGLI
. :*. :
Rv3618|M.tuberculosis_H37Rv LLLGHDWAPPPATFHSYELFARAVIPYFKG--------QLAAPRASHEWA
MAV_0538|M.avium_104 LMLGHDWASPEATYHCYDLMARKVIPHFKR--------QLDASRASHDWA
TH_3390|M.thermoresistible__bu IMNLADFAAPAAKLRSIELFAEYVIPEFTG--------HLDALRASHEWV
MMAR_2824|M.marinum_M LQMGHEWANPAATRRSAELFAAEVMPHFQG--------QAQPTLDAAVRA
MUL_2949|M.ulcerans_Agy99 LQMGHEWANPAATRRSAELFAAEVMPHFQG--------QAQPTLDAAVRA
Mflv_2404|M.gilvum_PYR-GCK ILLLNPRS-HEGTMESIEIMGRDILPEFIERDEKAVKDKAKRLEPVIEKV
Mvan_4242|M.vanbaalenii_PYR-1 ILLLNPRS-HEGTMESIEIMGRDILPEFIERDEKAVKDKAKRLEPVIEKV
MAB_3232c|M.abscessus_ATCC_199 FSLVYQAAQPGLGMQNVELYGTEVIPRVRE-------------LLAGDAV
MSMEG_4092|M.smegmatis_MC2_155 LSFVPGVPEHGEHLRLLEDTARELVPRLGW--------------YPSTGV
Mb1886c|M.bovis_AF2122/97 INLAPHGYLPGVITTAAEALRPLLGV------------------------
: : :
Rv3618|M.tuberculosis_H37Rv RGKRD--------------QLIGRAG-EAVVKAITEHVAEQGEAGS----
MAV_0538|M.avium_104 KGMRD--------------QLLGRAG-EAVVKAISEHVDEHKDAVH----
TH_3390|M.thermoresistible__bu LGAKN--------------EEDTTIWRDQTNAAIAAATAEFQRSRG----
MMAR_2824|M.marinum_M GEVRE--------------GLA-----QTQLQAIDHMTKKYQQELDSK--
MUL_2949|M.ulcerans_Agy99 GEVRE--------------GLA-----QTQLQAIDHMTKKYQQELDGK--
Mflv_2404|M.gilvum_PYR-GCK EARRQSWDAPMFDETYSFGGLPTGRGGKFTAGEIPEAMAEINEGRVKAAQ
Mvan_4242|M.vanbaalenii_PYR-1 EARRQSWDAPLFDETYAFGGLPTGRGGKFTAGEIPEAMAEINEGRVKAAQ
MAB_3232c|M.abscessus_ATCC_199 GAA-----------------------------------------------
MSMEG_4092|M.smegmatis_MC2_155 S-------------------------------------------------
Mb1886c|M.bovis_AF2122/97 --------------------------------------------------
Rv3618|M.tuberculosis_H37Rv -------------
MAV_0538|M.avium_104 -------------
TH_3390|M.thermoresistible__bu -------------
MMAR_2824|M.marinum_M -------------
MUL_2949|M.ulcerans_Agy99 -------------
Mflv_2404|M.gilvum_PYR-GCK AEKDARAAKEAAG
Mvan_4242|M.vanbaalenii_PYR-1 AEKDAKAAKEAAS
MAB_3232c|M.abscessus_ATCC_199 -------------
MSMEG_4092|M.smegmatis_MC2_155 -------------
Mb1886c|M.bovis_AF2122/97 -------------