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MLVSLMQFVTDLTPPPQLVAVWAEERGFAGLYVPEKTHVPISRSTPWPGGELPDWYRRCYDPVVALAAAA AVTTRLRVGTGACLVAVHDPILLAKQIASLCAMSGERFVLGVGFGWNVEELADHGVPFADRIAVTVDKLA AMRALWAAEPVHYEGTHASVPPSWAWPKPAVAPPVLFGCRPSARAFEVIARHGDGWQPIEGYGELLGALP MLHAAFERAGRDPATAQVCVYSSAGDPATLHEYRRAGVAEVALALPSAGRDQVLAALDRSAPLVDAFAGD DREVKSHA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2185c | - | - | 100% (288) | hypothetical protein Mb2185c |
| M. bovis AF2122 / 97 | Mb0978c | - | 1e-46 | 40.43% (277) | oxidoreductase |
| M. bovis AF2122 / 97 | Mb3106c | - | 1e-42 | 40.88% (274) | hypothetical protein Mb3106c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_1871 | - | 1e-48 | 42.03% (276) | luciferase family protein |
| M. tuberculosis H37Rv | Rv2161c | - | 1e-170 | 100.00% (288) | hypothetical protein Rv2161c |
| M. leprae Br4923 | MLBr_00348 | - | 1e-07 | 27.85% (158) | putative coenzyme F420-dependent oxidoreductase |
| M. abscessus ATCC 19977 | MAB_1059c | - | 9e-51 | 39.78% (279) | hypothetical protein MAB_1059c |
| M. marinum M | MMAR_4546 | - | 5e-49 | 42.01% (269) | oxidoreductase |
| M. avium 104 | MAV_1077 | - | 3e-50 | 43.33% (270) | hypothetical protein MAV_1077 |
| M. smegmatis MC2 155 | MSMEG_5520 | - | 9e-48 | 41.88% (277) | hypothetical protein MSMEG_5520 |
| M. thermoresistible (build 8) | TH_2830 | - | 2e-51 | 43.01% (272) | PUTATIVE luciferase family protein |
| M. ulcerans Agy99 | MUL_3458 | - | 2e-44 | 41.03% (273) | oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_4864 | - | 2e-49 | 42.75% (276) | luciferase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2185c|M.bovis_AF2122/97 -------------------MLVSLMQFVTDLTPPPQLVAVWAEERGFAGL
Rv2161c|M.tuberculosis_H37Rv -------------------MLVSLMQFVTDLTPPPQLVAVWAEERGFAGL
MUL_3458|M.ulcerans_Agy99 -------------------MRVGVLTFVTDEGIGPAELGAALEERGFESL
Mflv_1871|M.gilvum_PYR-GCK MQGWHPPCGRGLEHVLILGMNYGLVLFTSDRGITPAAAATLADQHGFETF
Mvan_4864|M.vanbaalenii_PYR-1 -------------------MNYGLVLFTSDRGITPAAAAKLADEHGFETF
MSMEG_5520|M.smegmatis_MC2_155 -------------------MDYGLVLFTSDRGITPASAAKLADDHGFTTF
MMAR_4546|M.marinum_M ------------------------MLFTSDRGIAPAAAARLADDHGFHTF
MAV_1077|M.avium_104 ------------------------MLFTSDRGISPAAAAKLADDHGFATF
TH_2830|M.thermoresistible__bu -------------------MDFGLVLFTSDRGITPAKAATLADDHGFTTF
MAB_1059c|M.abscessus_ATCC_199 -------------------MDYGLVLFTSDRGISPAIAAKAAEDGGFSTF
MLBr_00348|M.leprae_Br4923 -------------------------------MVERANAMKLGLQLGYWAA
: *:
Mb2185c|M.bovis_AF2122/97 YVPEKTHVPISRSTPWP---GGELP-DWYRRCYDPVVALAAAAAVTTRLR
Rv2161c|M.tuberculosis_H37Rv YVPEKTHVPISRSTPWP---GGELP-DWYRRCYDPVVALAAAAAVTTRLR
MUL_3458|M.ulcerans_Agy99 FLAEHTHIPVNNQSPYPP--GGPIP-RKYYRTLDPFVALTAAAVATESLV
Mflv_1871|M.gilvum_PYR-GCK YVPEHTHIPIKRQAAHPTTGDESLPDDRYMRTLDPWVSLGTAAAVTSRVR
Mvan_4864|M.vanbaalenii_PYR-1 YVPEHTHIPIKRQAAHPTTGDESLPDDRYMRTLDPWVSLGTAAAVTSRVR
MSMEG_5520|M.smegmatis_MC2_155 YVPEHTHIPIKREAAHPTTGDESLPDDRYMRTLDPWVSLGTAAAVTSRVG
MMAR_4546|M.marinum_M YVPEHTHIPIKREAAHPTTGDSSLPDDRYMRTLDPWVSLGAASAVTSRVR
MAV_1077|M.avium_104 YVPEHTHIPIKREAAHPTTGDASLPDDRYMRTLDPWVSLGAACAVTSRVR
TH_2830|M.thermoresistible__bu YVPEHTHIPVKREAAHPTTGDSSLPDDRYMRTLDPWVSLATASAVTSRVR
MAB_1059c|M.abscessus_ATCC_199 YVPEHTHIPVKREAAHPGTGGAELPDDRYMRTLDPWVSLGAACAVTSKIR
MLBr_00348|M.leprae_Br4923 QPPGNAAELVAAAEGAG--FDAVFTGEAWG--SDAYTPLAWWGSSTQRVR
. :: : . :. : *. ..* * :
Mb2185c|M.bovis_AF2122/97 VGTGACLVAVHDPILLAKQIASLCAMSGERFVLGVGFGWNVEELADHGVP
Rv2161c|M.tuberculosis_H37Rv VGTGACLVAVHDPILLAKQIASLCAMSGERFVLGVGFGWNVEELADHGVP
MUL_3458|M.ulcerans_Agy99 LGTGIALIPERDPIVTAKEVASLDVVSGGRFCFGVGVGWLREEVANHGVD
Mflv_1871|M.gilvum_PYR-GCK LSTAVALPVEHDCITLAKSIATLDHLSGGRVSLGVGFGWNTDELADHNVP
Mvan_4864|M.vanbaalenii_PYR-1 LSTAVALPVEHDPITLAKSIATLDHLSGGRVSLGVGFGWNTDELADHNVP
MSMEG_5520|M.smegmatis_MC2_155 LSTAVALPVEHDPITLAKSIATLDHLSGGRVSLGVGFGWNTDELADHKVP
MMAR_4546|M.marinum_M LSTAVALPVEHDPITLAKSIATLDHLSGGRVSLGVGFGWNTDELADHGVP
MAV_1077|M.avium_104 LSTAVALPVEHDPITLAKSIATLDHLSGGRVSLGVGFGWNTDELADHGVP
TH_2830|M.thermoresistible__bu LSTAVALPVEHDPISLAKTIASLDHLSGGRVSLGVGFGWNTDELVDHGVP
MAB_1059c|M.abscessus_ATCC_199 LATAVAIPVEHDPITLAKSIATLDHMSGGRVTVGVGYGWNTDELADHHVP
MLBr_00348|M.leprae_Br4923 LGTSVVQLSARTPTACAMAALTLDHLSGGRHILGLGVSGPQVVEGWYGQP
:.*. : * :* :** * .*:* . :
Mb2185c|M.bovis_AF2122/97 FADRIAVTVDKLAAMRALWAAEP-VHYEGTHASVPPSWAWP-------KP
Rv2161c|M.tuberculosis_H37Rv FADRIAVTVDKLAAMRALWAAEP-VHYEGTHASVPPSWAWP-------KP
MUL_3458|M.ulcerans_Agy99 PAVRGRVSDERLGAMIEIWTQDN-AEYHGKYVDFDPICCWP-------KP
Mflv_1871|M.gilvum_PYR-GCK PGRRRTMLREYLEAMRALWTQEE-AEYDGEFVKFGPSWAWP-------KP
Mvan_4864|M.vanbaalenii_PYR-1 PGRRRTMLREYLEAMRALWTQEE-AEFDGEFVKFGPSWAWP-------KP
MSMEG_5520|M.smegmatis_MC2_155 AGRRRTMLREYLEAMRALWTQEE-ASYDGEFVNFGPSWAWP-------KP
MMAR_4546|M.marinum_M PGRRRTMLREYLEAMRALWTQEE-AAYDGEFVKFGPSWAWP-------KP
MAV_1077|M.avium_104 AGRRRTMLREYLEAMRALWTQEE-AAYDGEFVKFGPSWAWP-------KP
TH_2830|M.thermoresistible__bu PKRRRTMLREYLEAMRALWTQEE-ASYQGEFVSFGPSWAWP-------KP
MAB_1059c|M.abscessus_ATCC_199 AGRRRTMLREYIEAMRRLWEEEE-ASYSGEFVNFGPSWAWP-------KT
MLBr_00348|M.leprae_Br4923 FPKPLSRTREYIDIVRQVWAREAPVVSDGQHYPLPLTGAGATGLGKALKP
: : : :* : . * . . . . *.
Mb2185c|M.bovis_AF2122/97 AVAP-----PVLFGCRPSARAFEVIARHGDGWQPIEG-------------
Rv2161c|M.tuberculosis_H37Rv AVAP-----PVLFGCRPSARAFEVIARHGDGWQPIEG-------------
MUL_3458|M.ulcerans_Agy99 VTKPH---PPLYIGGGPAS--FGRIARLGAGWIAISP-------------
Mflv_1871|M.gilvum_PYR-GCK VQSH----IPVLVGAAGTEKNFKWIAKSADGWITTPR-------------
Mvan_4864|M.vanbaalenii_PYR-1 VQAH----IPVLVGAAGTEKNFKWIAKSADGWITTPR-------------
MSMEG_5520|M.smegmatis_MC2_155 VQAH----IPVLVGAAGNEKNFKWIARSADGWITTPR-------------
MMAR_4546|M.marinum_M VQSH----IPVLVGAAGTEKNFKWIARSADGWITTPR-------------
MAV_1077|M.avium_104 VQPH----IPVLVGAAGNEKNFKWIARSADGWITTPR-------------
TH_2830|M.thermoresistible__bu VQAH----IPVLVGAAGTEKNFKWIARSADGWITTPR-------------
MAB_1059c|M.abscessus_ATCC_199 VQKH----VPVIVGAGGTEKNFTWIAKNADGWMSTPR-------------
MLBr_00348|M.leprae_Br4923 ITHPLRADIPIMLG-AEGPKNVALAAEICDGWLPIFFSPRMADMYNEWLD
*: .* . *. ** .
Mb2185c|M.bovis_AF2122/97 -------------YGELLGALPMLHAAFERAGRDPATAQVCVYSSAG---
Rv2161c|M.tuberculosis_H37Rv -------------YGELLGALPMLHAAFERAGRDPATAQVCVYSSAG---
MUL_3458|M.ulcerans_Agy99 -------------SPQLLAGP--LEELRSLAG-EEVAVTVCLSDET----
Mflv_1871|M.gilvum_PYR-GCK -------------DFTIDEPVKLLQDTWAAAGRDGAPQIVALDFKP----
Mvan_4864|M.vanbaalenii_PYR-1 -------------DFTIDEPVKLLQDTWAAAGRDGAPQIVALDFKP----
MSMEG_5520|M.smegmatis_MC2_155 -------------DFDIDEPVKLLQDIWAAAGREGAPQIRALDYKP----
MMAR_4546|M.marinum_M -------------DFDIDAPVKLLQDTWAAAGRDGAPQIVALDFKP----
MAV_1077|M.avium_104 -------------DFDIDEPVKLLQDTWAAAGRDGAPQIVALDFKP----
TH_2830|M.thermoresistible__bu -------------DVDIEEPVKLLQDIWADAGRDGAPQIVALDFKP----
MAB_1059c|M.abscessus_ATCC_199 -------------DEDIAGKIVALKEAWKAAGRDGDPLIYVLAGKP----
MLBr_00348|M.leprae_Br4923 EGFARTGARRSREDFEICASAQIVVTEDRAAAFAGIKPFLALYMGGMGAE
: : *. :
Mb2185c|M.bovis_AF2122/97 -DPATLHEYRRAGVAEVALALPSAGRDQ------------------VLAA
Rv2161c|M.tuberculosis_H37Rv -DPATLHEYRRAGVAEVALALPSAGRDQ------------------VLAA
MUL_3458|M.ulcerans_Agy99 -KVSDLEGYLPLGVERVLLGLPTEPRDQ------------------TLRY
Mflv_1871|M.gilvum_PYR-GCK -DPDKLAHWRELGVTEVLFGLPDKSESE------------------VAAY
Mvan_4864|M.vanbaalenii_PYR-1 -DPEKLAHWREIGVTEVLFGLPDKSEAD------------------VAAY
MSMEG_5520|M.smegmatis_MC2_155 -DAEKLAHWRDLGVTEVVFGLPDKSEAE------------------VAAY
MMAR_4546|M.marinum_M -VPEKLARWAELGVTEVLFGLPDRPEDE------------------IAAY
MAV_1077|M.avium_104 -DAEKLARWAELGVTEVLFGLPDKSEDE------------------VAAY
TH_2830|M.thermoresistible__bu -DPDKLARWRDLGVTEVLFGLPDRSDDE------------------IAAY
MAB_1059c|M.abscessus_ATCC_199 -DPEQLAAWRELGVTEAIFGMPDRSEEE------------------VRAY
MLBr_00348|M.leprae_Br4923 GTNFHADVYRRMGYAEVVDEVTALFRSNQKDKAAEIIPNELVDSTMIVGD
: * .. :. :
Mb2185c|M.bovis_AF2122/97 LDRSAPLVDAFAGDDREVKSHA--------------
Rv2161c|M.tuberculosis_H37Rv LDRSAPLVDAFAGDDREVKSHA--------------
MUL_3458|M.ulcerans_Agy99 LDQMESELVQLG------------------------
Mflv_1871|M.gilvum_PYR-GCK VERLAGKLAQLV------------------------
Mvan_4864|M.vanbaalenii_PYR-1 VERLAGKLGALT------------------------
MSMEG_5520|M.smegmatis_MC2_155 VERLAGKLSALV------------------------
MMAR_4546|M.marinum_M VERLAGKLAAMV------------------------
MAV_1077|M.avium_104 VERLAGKLAALV------------------------
TH_2830|M.thermoresistible__bu VERLAGKLGLS-------------------------
MAB_1059c|M.abscessus_ATCC_199 IDRLSGKLAAFA------------------------
MLBr_00348|M.leprae_Br4923 VDYVCKQIAAWSAAGVTMMMVSASSVEQVRDLAGLF
:: :