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M. abscessus ATCC 19977 MAB_4609c (-)

annotation: putative acyl-CoA dehydrogenase FadE
coordinates: 4695117 - 4696298
length: 393

ATDAAPTNPDELFGIDALLSDEERAIRDSVRALVQARVVPNVQRWYEHGDLPVRKLALELGKIGVLGMHL
HGYGCSGTSSLAYGLACMELEAGDSGIRSLVSVQGSLAMYAIYAYGSDAQKQKWLPRMATGEELGCFGLT
EPDFGSNPGGMRTHARRDGSDWVLNGTKMWITNGSIADVAVIWAQTDEGVRGFLVSTDSAGFDAQTIHSK
MSLRASVTAELNLVDVWVPEKNRLPLAVGLKAPLSCLNEARFGIIFGSMGAARECLRTALEYAQTREQFD
RPIAGFQLTQEKLANMALEYGKGVLLALHLGRRKDADTLATPQVSLGKLNNVREAIEIARTARTILGANG
ISGEYPVMRHANNLESVLTYEGTSEMHTLVIGQALTGIAAFR*

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. abscessus ATCC 19977 MAB_4609c - - 100% (393) putative acyl-CoA dehydrogenase FadE
M. abscessus ATCC 19977 MAB_0822 - e-147 65.28% (386) acyl-CoA dehydrogenase
M. abscessus ATCC 19977 MAB_4538c - 4e-42 31.68% (382) putative acyl-CoA dehydrogenase FadE

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb0406c fadE7 1e-143 64.21% (394) acyl-CoA dehydrogenase FADE7
M. gilvum PYR-GCK Mflv_4513 - 1e-149 64.68% (402) acyl-CoA dehydrogenase domain-containing protein
M. tuberculosis H37Rv Rv0400c fadE7 1e-143 64.21% (394) acyl-CoA dehydrogenase FADE7
M. leprae Br4923 MLBr_00737 fadE25 4e-36 27.89% (380) putative acyl-CoA dehydrogenase
M. marinum M MMAR_0698 fadE7 1e-146 65.06% (395) acyl-CoA dehydrogenase FadE7
M. avium 104 MAV_4767 - 1e-151 66.08% (398) putative acyl-CoA dehydrogenase
M. smegmatis MC2 155 MSMEG_2466 - 1e-168 74.41% (383) glutaryl-CoA dehydrogenase
M. thermoresistible (build 8) TH_2172 - 1e-151 65.89% (384) glutaryl-CoA dehydrogenase
M. ulcerans Agy99 MUL_2825 fadE7 1e-146 65.06% (395) acyl-CoA dehydrogenase FadE7
M. vanbaalenii PYR-1 Mvan_4671 - 1e-150 66.58% (386) acyl-CoA dehydrogenase domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


Mb0406c|M.bovis_AF2122/97           ----MSTPTPPALDR--DDPLGLDASLSSDEIAVRDTVRRFCAEHVTPHV
Rv0400c|M.tuberculosis_H37Rv        ----MSTPTPPALDR--DDPLGLDASLSSDEIAVRDTVRRFCAEHVTPHV
MMAR_0698|M.marinum_M               ----MSTETPPTFDP--HDPLGLDASLSDDEIAVRDTVRKFCAEHITAHV
MUL_2825|M.ulcerans_Agy99           ----MSTETPPTFDP--HDPLGLDASLSDDEIAVRDTVRKFCAEHITAHV
MAV_4767|M.avium_104                MSTETSTKTPPAFDR--YDPLGLDALLSDDERAVRDTVRGFCAEHVLPHV
MAB_4609c|M.abscessus_ATCC_199      MATDAAPTNP-------DELFGIDALLSDEERAIRDSVRALVQARVVPNV
MSMEG_2466|M.smegmatis_MC2_155      -MTNSAVAQPRSQRRGADDLIGINAVLSAEEREIRDTVRSVVQRRIKPHI
TH_2172|M.thermoresistible__bu      ------------VD----DLLDLDALLTPEDIELRDTVRRFGEQRLRPHV
Mvan_4671|M.vanbaalenii_PYR-1       MPAHQPLPTTTTIE----NLLDLDSLLSAEDRDLRTMVRGFGEQRLRPQI
Mflv_4513|M.gilvum_PYR-GCK          MSTTTAPATKAVYAP--LELFDTARLLEQDEREIAATVRKFVDSELKPNV
MLBr_00737|M.leprae_Br4923          ------------MVGWSGNPLFDLFKLPEEHNELRATIRALAEKEIAPHA
                                                      : :     *  :.  :   :* .   .: .: 

Mb0406c|M.bovis_AF2122/97           AAWFEDGDLPVARDLAKQFGELGLLGMQL-HGHGCGGASAVHYGLACREL
Rv0400c|M.tuberculosis_H37Rv        AAWFEDGDLPVARDLAKQFGELGLLGMQL-HGHGCGGASAVHYGLACREL
MMAR_0698|M.marinum_M               AEWFENGDLPAARDLAKQLGGLGLLGMHL-QGYGCGGASAVHYGLACLEL
MUL_2825|M.ulcerans_Agy99           AEWFENGDLPAARDLAKQLGGLGLLGMHL-QGYGCGGASAVHYGLACLEL
MAV_4767|M.avium_104                AEWFEIGDLP-VRELAREFGRLGLLGMHL-HGYGCGGASAVHYGLACVEL
MAB_4609c|M.abscessus_ATCC_199      QRWYEHGDLP-VRKLALELGKIGVLGMHL-HGYGCSGTSSLAYGLACMEL
MSMEG_2466|M.smegmatis_MC2_155      ASWYEDGELP-ARELAVELGELGLLGMHL-KGYGCAGMSAVAYGLACLEL
TH_2172|M.thermoresistible__bu      ADWFESGQIP-VRELAADLGKLGLLGMHL-QGYGCSGSTATAYGLVCQEL
Mvan_4671|M.vanbaalenii_PYR-1       AEWFEAGQVP-VRELAAEIGKLGLLGMHL-QGYGCSGSTATAYGLVCQEL
Mflv_4513|M.gilvum_PYR-GCK          EDWFESATLP--KELGKRFGELGLLGMHL-QGYGCAGTNAVSYGLACMEL
MLBr_00737|M.leprae_Br4923          ADVDQRARFP--EEALAALNASGFNAIHVPEEYGGQGADSVAACIVIEEV
                                        : . .*  ..    :.  *. .::: . :*  *  :    :.  *:

Mb0406c|M.bovis_AF2122/97           EAADSGIRSLVSVQGSLAMFAIASFGSDEQKRQWLPGMATGDLLGCFGLT
Rv0400c|M.tuberculosis_H37Rv        EAADSGIRSLVSVQGSLAMFAIASFGSDEQKRQWLPGMATGDLLGCFGLT
MMAR_0698|M.marinum_M               EAADSGIRSLVSVQGSLAMFAIAHFGSEEHKQRWLPPMAAGELIGCFGLT
MUL_2825|M.ulcerans_Agy99           EAADSGIRSLVSVQGSLAMFAIAHFGSEEHKQRWLPPMAAGELIGCFGLT
MAV_4767|M.avium_104                EAADSGLRSMVSVQGSLAMFAIWNFGSEEQKRQWLPGMATGEMLGCFGLT
MAB_4609c|M.abscessus_ATCC_199      EAGDSGIRSLVSVQGSLAMYAIYAYGSDAQKQKWLPRMATGEELGCFGLT
MSMEG_2466|M.smegmatis_MC2_155      EAGDSGIRSLVSVQGSLAMYAIHAFGSDEQKDQWLPDMASGHRIGCFGLT
TH_2172|M.thermoresistible__bu      EAVDSGLRSLVSVQGSLAMFAIYRHGSEEQRRHWLPPMATGEVIGCFGLT
Mvan_4671|M.vanbaalenii_PYR-1       EAVDSGLRSLVSVQGSLAMFAIHRWGSEEQRTRWLPGMAAGELIGCFGLT
Mflv_4513|M.gilvum_PYR-GCK          EAGDSGFRSFVSVQGSLSMFSIHRYGSEEQKNEWLPRLASGDAIGCFGLT
MLBr_00737|M.leprae_Br4923          ARVDASASLIPAVN-KLGTMGLILRGSEELKKQVLPSLAAEGAMASYALS
                                       *:.   : :*: .*.  .:   **:  : . ** :*:   :..:.*:

Mb0406c|M.bovis_AF2122/97           EPDVGSDPAAMKTRARRDGP----DWVITGGKMWITNGSVADVAIVWAAT
Rv0400c|M.tuberculosis_H37Rv        EPDVGSDPAAMKTRARRDGP----DWVITGGKMWITNGSVADVAIVWAAT
MMAR_0698|M.marinum_M               EPDVGSDPAAMKTRARRDGS----DWVLNGRKMWITNGSIADVAIVWAAT
MUL_2825|M.ulcerans_Agy99           EPDVGSDPAAMKTRARRDGS----DWVLNGRKMWITNGSIADVAIVWAAT
MAV_4767|M.avium_104                EPDVGSDPAAMKTRARRDGS----DWVLDGRKLWITNGSVADVAVVWAGT
MAB_4609c|M.abscessus_ATCC_199      EPDFGSNPGGMRTHARRDGS----DWVLNGTKMWITNGSIADVAVIWAQT
MSMEG_2466|M.smegmatis_MC2_155      EPDHGSDPAGMRTRATRSGD----DWILTGTKMWITNGSVADVAVVWART
TH_2172|M.thermoresistible__bu      EPDFGSNPAGMRTTARRDGS----DWILNGSKMWITNGSVADVAIVWARS
Mvan_4671|M.vanbaalenii_PYR-1       EPDFGSNPGGMRTTARRDGS----DWILNGSKMWITNASVADVAIIWARS
Mflv_4513|M.gilvum_PYR-GCK          EPDFGSNPAGMRTRGKRDGSGENADWILNGTKMWITNGNLADVATVWAQT
MLBr_00737|M.leprae_Br4923          EREAGSDAASMRTRAKADGD----DWILNGFKCWITNGGKSTWYTVMAVT
                                    * : **:...*:* .  .*     **:: * * ****.. :    : * :

Mb0406c|M.bovis_AF2122/97           DD-----GIRGFIVPTDTPGFTANTIGHKLSLRASITSELVLDNVRLPAD
Rv0400c|M.tuberculosis_H37Rv        DD-----GIRGFIVPTDTPGFTANTIGHKLSLRASITSELVLDNVRLPAD
MMAR_0698|M.marinum_M               EE-----GIRGFVVPTETAGFAANTIHHKLSLRASITSELVLDDVRLPAE
MUL_2825|M.ulcerans_Agy99           EE-----GIRGFVVPTETAGFAANTIHHKLSLRASITSELVLDDVRLPAE
MAV_4767|M.avium_104                DD-----GIRGFLVPTDTPGFTANTIHHKLSLRASITSELVLDDVRLPGE
MAB_4609c|M.abscessus_ATCC_199      DE-----GVRGFLVSTDSAGFDAQTIHSKMSLRASVTAELNLVDVWVPEK
MSMEG_2466|M.smegmatis_MC2_155      DE-----GIRGFVVPTDTPGFTANTIKSKMSLRASVTSELVLDGVRLPDS
TH_2172|M.thermoresistible__bu      ADD----GILGFVVPTDTPGFTAREMTRKLSLRASVTSELHLDDVRLPAD
Mvan_4671|M.vanbaalenii_PYR-1       KE-----GVLGFAVPTSTPGFHATEMTRKLSLRASVTSEIHLDDVRVPED
Mflv_4513|M.gilvum_PYR-GCK          DE-----GIRGFLVPTDTPGFTANAIHRKLSLRASITSELVLDNVRLPAS
MLBr_00737|M.leprae_Br4923          DPDKGANGISAFIVHKDDEGFSIGPKEKKLGIKGSPTTELYFDKCRIPGD
                                           *: .* * ..  **       *:.::.* *:*: :    :* .

Mb0406c|M.bovis_AF2122/97           AMLPG-ATGLRAPLACLSEARYGIVWGAMGAARSAWQCALDYARQRTQFG
Rv0400c|M.tuberculosis_H37Rv        AMLPG-ATGLRAPLACLSEARYGIVWGAMGAARSAWQCALDYARQRTQFG
MMAR_0698|M.marinum_M               AMLPG-ATGVRGPLTCLSEARYGIVWGAMGAARSAWQCALDYAKERTQFG
MUL_2825|M.ulcerans_Agy99           AMLPG-ATGVRGPLTCLSEARYGIVWGAMGAARSAWQCALDYAKERTQFG
MAV_4767|M.avium_104                AMLPG-ATGLRGPLSCLSEARYGIIWGAMGAARSAWQAALDYATQRTQFG
MAB_4609c|M.abscessus_ATCC_199      NRLPL-AVGLKAPLSCLNEARFGIIFGSMGAARECLRTALEYAQTREQFD
MSMEG_2466|M.smegmatis_MC2_155      ARLPG-ATSLGAPLRCLNEARFGIVFGALGAARDCLETALAYACSREQFD
TH_2172|M.thermoresistible__bu      ARLPG-ARGLSGPLACLSEARFGIVFGSVGAARDCLETTLDYVATREVFD
Mvan_4671|M.vanbaalenii_PYR-1       ARLPE-AQGLKAPLSCLSEARFGIVFGAVGAARDCLQTTLDYVGTRAVFD
Mflv_4513|M.gilvum_PYR-GCK          AQLPE-AVGLSAPLSCLNEARFGIVFGALGAARDSLETTIAYTQTREVFD
MLBr_00737|M.leprae_Br4923          RIIGEPGTGFKTALATLDHTRPTIGAQAVGIAQGALDAAIVYTKDRKQFG
                                      :   . ..  .*  *..:*  *   ::* *: .   :: *.  *  *.

Mb0406c|M.bovis_AF2122/97           RPIAGFQLTQAKLVDMAVELHKGQLLSLHLGRLKDRVGLRPDQVSFG-KL
Rv0400c|M.tuberculosis_H37Rv        RPIAGFQLTQAKLVDMAVELHKGQLLSLHLGRLKDRVGLRPDQVSFG-KL
MMAR_0698|M.marinum_M               RPIAGFQLTQAKLVDMAVELHKGQLLALQLGRLKDSVGLRPEQVSFG-KL
MUL_2825|M.ulcerans_Agy99           RPIAGFQLTQAKLVDMAVELHKGQLLALQLGRLKDSVGLRPEQVSFG-KL
MAV_4767|M.avium_104                RPIAGFQLTQAKLVDMAVELHKGQLLSLHLGRLKDSTGLRPEQVSFG-KL
MAB_4609c|M.abscessus_ATCC_199      RPIAGFQLTQEKLANMALEYGKGVLLALHLGRRKDADTLATPQVSLG-KL
MSMEG_2466|M.smegmatis_MC2_155      RPIGGFQLTQQKLADMTLEYGKGFLLALHLGRQKDAGELAPEQVSLG-KL
TH_2172|M.thermoresistible__bu      KPLAGYQITQTKLADMAVELGKAQLLALHLGRLKDGGTIRPEQISVG-KL
Mvan_4671|M.vanbaalenii_PYR-1       RPLAGYQLTQAKIADMAVELGKAQLLALHLGRLKDEGRIRPEQVSVG-KL
Mflv_4513|M.gilvum_PYR-GCK          RPLAGYQLTQEKLANMTVELGKGMLLAIHLGRIKDAEGVRPEQVSLG-KL
MLBr_00737|M.leprae_Br4923          ESISTFQSIQFMLADMAMKVEAARLIVYAAAARAERGEPDLGFISAASKC
                                    ..:. :*  *  :.:*:::   . *:    .   :        :* . * 

Mb0406c|M.bovis_AF2122/97           NNTREALKICRTARTILGGNGISLEYPVIRHMVNLESVLTYEGTPEMHQL
Rv0400c|M.tuberculosis_H37Rv        NNTREALKICRTARTILGGNGISLEYPVIRHMVNLESVLTYEGTPEMHQL
MMAR_0698|M.marinum_M               NNTREAIKICRTARTILGGNGISLEYPVIRHMVNLESVLTYEGTPEMHQL
MUL_2825|M.ulcerans_Agy99           NNTREAIKICRTARTILGGNGISLEYPVIRHMVNLESVLTYEGTPEMHQL
MAV_4767|M.avium_104                NNTREAIEICRTARTILGGNGISLEYPVIRHMVNLESVLTYEGTPEMHQL
MAB_4609c|M.abscessus_ATCC_199      NNVREAIEIARTARTILGANGISGEYPVMRHANNLESVLTYEGTSEMHTL
MSMEG_2466|M.smegmatis_MC2_155      NNVREAIEIARTARTVLGASGITGEYPVMRHANNLESVLTYEGTSEMHTL
TH_2172|M.thermoresistible__bu      NNVREALRIARECRTLLGANGVTLEYPVLRHANNLESVLTYEGTSEVHQL
Mvan_4671|M.vanbaalenii_PYR-1       NNVREAIKIARQCRTLLGANGITLEYPVLRHANNLESVLTYEGTSEVHQL
Mflv_4513|M.gilvum_PYR-GCK          NNVREAIAIARECRTLLGGSGITLEYSPLRHANNLESVLTYEGTSEMHLL
MLBr_00737|M.leprae_Br4923          FASDIAMEVTTDAVQLFGGAGYTSDFPVERFMRDAKITQIYEGTNQIQRV
                                         *: :   .  ::*. * : ::.  *.  : : .  **** ::: :

Mb0406c|M.bovis_AF2122/97           VLGQAFTGLAAFR-
Rv0400c|M.tuberculosis_H37Rv        VLGQAFTGLAAFR-
MMAR_0698|M.marinum_M               VLGQAFTGLAAFR-
MUL_2825|M.ulcerans_Agy99           VLGQAFTGLAAFR-
MAV_4767|M.avium_104                VLGQAFTGADAFR-
MAB_4609c|M.abscessus_ATCC_199      VIGQALTGIAAFR-
MSMEG_2466|M.smegmatis_MC2_155      IIGQALTGVGAFR-
TH_2172|M.thermoresistible__bu      VIGQTMTGLSAFR-
Mvan_4671|M.vanbaalenii_PYR-1       VIGEALTGVGAFR-
Mflv_4513|M.gilvum_PYR-GCK          SIGKALTGHAAFRA
MLBr_00737|M.leprae_Br4923          VMSRALLR------
                                     :..::

species	id	gene	e-value	identity (len)	annotation
M. abscessus ATCC 19977	MAB_4609c	-	-	100% (393)	putative acyl-CoA dehydrogenase FadE
M. abscessus ATCC 19977	MAB_0822	-	e-147	65.28% (386)	acyl-CoA dehydrogenase
M. abscessus ATCC 19977	MAB_4538c	-	4e-42	31.68% (382)	putative acyl-CoA dehydrogenase FadE