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M. thermoresistible (build 8) TH_2172 (-)

annotation: glutaryl-CoA dehydrogenase
coordinates: 4259017 - 4260174
length: 386

aa seq not available

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. thermoresistible (build 8) TH_2172 - - 100% (386) glutaryl-CoA dehydrogenase
M. thermoresistible (build 8) TH_2782 - 2e-50 33.51% (370) PUTATIVE acyl-CoA dehydrogenase domain protein
M. thermoresistible (build 8) TH_3610 - 5e-50 34.83% (379) PUTATIVE acyl-CoA dehydrogenase domain protein

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb0406c fadE7 1e-151 67.79% (385) acyl-CoA dehydrogenase FADE7
M. gilvum PYR-GCK Mflv_4513 - 1e-154 68.73% (387) acyl-CoA dehydrogenase domain-containing protein
M. tuberculosis H37Rv Rv0400c fadE7 1e-151 67.79% (385) acyl-CoA dehydrogenase FADE7
M. leprae Br4923 MLBr_00737 fadE25 2e-45 31.91% (376) putative acyl-CoA dehydrogenase
M. abscessus ATCC 19977 MAB_4609c - 1e-151 65.89% (384) putative acyl-CoA dehydrogenase FadE
M. marinum M MMAR_0698 fadE7 1e-150 67.45% (384) acyl-CoA dehydrogenase FadE7
M. avium 104 MAV_4767 - 1e-154 68.15% (383) putative acyl-CoA dehydrogenase
M. smegmatis MC2 155 MSMEG_5267 - 0.0 85.71% (385) glutaryl-CoA dehydrogenase
M. ulcerans Agy99 MUL_2825 fadE7 1e-150 67.45% (384) acyl-CoA dehydrogenase FadE7
M. vanbaalenii PYR-1 Mvan_4671 - 0.0 83.38% (385) acyl-CoA dehydrogenase domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


Mb0406c|M.bovis_AF2122/97           ----MSTPTPPALDRDDPLGLDASLSSDEIAVRDTVRRFCAEHVTPHVAA
Rv0400c|M.tuberculosis_H37Rv        ----MSTPTPPALDRDDPLGLDASLSSDEIAVRDTVRRFCAEHVTPHVAA
MMAR_0698|M.marinum_M               ----MSTETPPTFDPHDPLGLDASLSDDEIAVRDTVRKFCAEHITAHVAE
MUL_2825|M.ulcerans_Agy99           ----MSTETPPTFDPHDPLGLDASLSDDEIAVRDTVRKFCAEHITAHVAE
MAV_4767|M.avium_104                MSTETSTKTPPAFDRYDPLGLDALLSDDERAVRDTVRGFCAEHVLPHVAE
TH_2172|M.thermoresistible__bu      ------------VD--DLLDLDALLTPEDIELRDTVRRFGEQRLRPHVAD
MSMEG_5267|M.smegmatis_MC2_155      MAPSNAAAGTTAVA--DLLDTDSMLNPEELELRSTVRRFGEQRLRPFVAE
Mvan_4671|M.vanbaalenii_PYR-1       MPAHQPLPTTTTIE--NLLDLDSLLSAEDRDLRTMVRGFGEQRLRPQIAE
Mflv_4513|M.gilvum_PYR-GCK          MSTTTAPATKAVYAPLELFDTARLLEQDEREIAATVRKFVDSELKPNVED
MAB_4609c|M.abscessus_ATCC_199      MATDAAPTNP---D--ELFGIDALLSDEERAIRDSVRALVQARVVPNVQR
MLBr_00737|M.leprae_Br4923          ---------MVGWSGNPLFDLFKLPEEHN-ELRATIRALAEKEIAPHAAD
                                                      :.       .:  :   :* :   .: .    

Mb0406c|M.bovis_AF2122/97           WFEDGDLPVARDLAKQFGELGLLGMQL-HGHGCGGASAVHYGLACRELEA
Rv0400c|M.tuberculosis_H37Rv        WFEDGDLPVARDLAKQFGELGLLGMQL-HGHGCGGASAVHYGLACRELEA
MMAR_0698|M.marinum_M               WFENGDLPAARDLAKQLGGLGLLGMHL-QGYGCGGASAVHYGLACLELEA
MUL_2825|M.ulcerans_Agy99           WFENGDLPAARDLAKQLGGLGLLGMHL-QGYGCGGASAVHYGLACLELEA
MAV_4767|M.avium_104                WFEIGDLP-VRELAREFGRLGLLGMHL-HGYGCGGASAVHYGLACVELEA
TH_2172|M.thermoresistible__bu      WFESGQIP-VRELAADLGKLGLLGMHL-QGYGCSGSTATAYGLVCQELEA
MSMEG_5267|M.smegmatis_MC2_155      WFESGSVP-VRELATEFGKLGLLGMHL-EGYGCGGSSATAYGVACQELEA
Mvan_4671|M.vanbaalenii_PYR-1       WFEAGQVP-VRELAAEIGKLGLLGMHL-QGYGCSGSTATAYGLVCQELEA
Mflv_4513|M.gilvum_PYR-GCK          WFESATLP--KELGKRFGELGLLGMHL-QGYGCAGTNAVSYGLACMELEA
MAB_4609c|M.abscessus_ATCC_199      WYEHGDLP-VRKLALELGKIGVLGMHL-HGYGCSGTSSLAYGLACMELEA
MLBr_00737|M.leprae_Br4923          VDQRARFP--EEALAALNASGFNAIHVPEEYGGQGADSVAACIVIEEVAR
                                      : . .*  ..    :.  *. .::: . :*  *: :    :.  *:  

Mb0406c|M.bovis_AF2122/97           ADSGIRSLVSVQGSLAMFAIASFGSDEQKRQWLPGMATGDLLGCFGLTEP
Rv0400c|M.tuberculosis_H37Rv        ADSGIRSLVSVQGSLAMFAIASFGSDEQKRQWLPGMATGDLLGCFGLTEP
MMAR_0698|M.marinum_M               ADSGIRSLVSVQGSLAMFAIAHFGSEEHKQRWLPPMAAGELIGCFGLTEP
MUL_2825|M.ulcerans_Agy99           ADSGIRSLVSVQGSLAMFAIAHFGSEEHKQRWLPPMAAGELIGCFGLTEP
MAV_4767|M.avium_104                ADSGLRSMVSVQGSLAMFAIWNFGSEEQKRQWLPGMATGEMLGCFGLTEP
TH_2172|M.thermoresistible__bu      VDSGLRSLVSVQGSLAMFAIYRHGSEEQRRHWLPPMATGEVIGCFGLTEP
MSMEG_5267|M.smegmatis_MC2_155      VDSGLRSMVSVQGSLAMFAIHAHGSEEQREQWLPRMATGEVIGCFGLTEP
Mvan_4671|M.vanbaalenii_PYR-1       VDSGLRSLVSVQGSLAMFAIHRWGSEEQRTRWLPGMAAGELIGCFGLTEP
Mflv_4513|M.gilvum_PYR-GCK          GDSGFRSFVSVQGSLSMFSIHRYGSEEQKNEWLPRLASGDAIGCFGLTEP
MAB_4609c|M.abscessus_ATCC_199      GDSGIRSLVSVQGSLAMYAIYAYGSDAQKQKWLPRMATGEELGCFGLTEP
MLBr_00737|M.leprae_Br4923          VDASASLIPAVN-KLGTMGLILRGSEELKKQVLPSLAAEGAMASYALSER
                                     *:.   : :*: .*.  .:   **:  : . ** :*:   :..:.*:* 

Mb0406c|M.bovis_AF2122/97           DVGSDPAAMKTRARRDGP----DWVITGGKMWITNGSVADVAIVWAAT--
Rv0400c|M.tuberculosis_H37Rv        DVGSDPAAMKTRARRDGP----DWVITGGKMWITNGSVADVAIVWAAT--
MMAR_0698|M.marinum_M               DVGSDPAAMKTRARRDGS----DWVLNGRKMWITNGSIADVAIVWAAT--
MUL_2825|M.ulcerans_Agy99           DVGSDPAAMKTRARRDGS----DWVLNGRKMWITNGSIADVAIVWAAT--
MAV_4767|M.avium_104                DVGSDPAAMKTRARRDGS----DWVLDGRKLWITNGSVADVAVVWAGT--
TH_2172|M.thermoresistible__bu      DFGSNPAGMRTTARRDGS----DWILNGSKMWITNGSVADVAIVWARSA-
MSMEG_5267|M.smegmatis_MC2_155      DFGSNPSGMRTTARRDGS----DWILNGSKMWITNGSVADVAIVWARS--
Mvan_4671|M.vanbaalenii_PYR-1       DFGSNPGGMRTTARRDGS----DWILNGSKMWITNASVADVAIIWARS--
Mflv_4513|M.gilvum_PYR-GCK          DFGSNPAGMRTRGKRDGSGENADWILNGTKMWITNGNLADVATVWAQT--
MAB_4609c|M.abscessus_ATCC_199      DFGSNPGGMRTHARRDGS----DWVLNGTKMWITNGSIADVAVIWAQT--
MLBr_00737|M.leprae_Br4923          EAGSDAASMRTRAKADGD----DWILNGFKCWITNGGKSTWYTVMAVTDP
                                    : **:...*:* .: **     **:: * * ****.. :    : * :  

Mb0406c|M.bovis_AF2122/97           ---DDGIRGFIVPTDTPGFTANTIGHKLSLRASITSELVLDNVRLPADAM
Rv0400c|M.tuberculosis_H37Rv        ---DDGIRGFIVPTDTPGFTANTIGHKLSLRASITSELVLDNVRLPADAM
MMAR_0698|M.marinum_M               ---EEGIRGFVVPTETAGFAANTIHHKLSLRASITSELVLDDVRLPAEAM
MUL_2825|M.ulcerans_Agy99           ---EEGIRGFVVPTETAGFAANTIHHKLSLRASITSELVLDDVRLPAEAM
MAV_4767|M.avium_104                ---DDGIRGFLVPTDTPGFTANTIHHKLSLRASITSELVLDDVRLPGEAM
TH_2172|M.thermoresistible__bu      ---DDGILGFVVPTDTPGFTAREMTRKLSLRASVTSELHLDDVRLPADAR
MSMEG_5267|M.smegmatis_MC2_155      ---EDGILGFVVPTDTPGFVGREMKHKLSLRASNTSELHLDDVRLPAEAQ
Mvan_4671|M.vanbaalenii_PYR-1       ---KEGVLGFAVPTSTPGFHATEMTRKLSLRASVTSEIHLDDVRVPEDAR
Mflv_4513|M.gilvum_PYR-GCK          ---DEGIRGFLVPTDTPGFTANAIHRKLSLRASITSELVLDNVRLPASAQ
MAB_4609c|M.abscessus_ATCC_199      ---DEGVRGFLVSTDSAGFDAQTIHSKMSLRASVTAELNLVDVWVPEKNR
MLBr_00737|M.leprae_Br4923          DKGANGISAFIVHKDDEGFSIGPKEKKLGIKGSPTTELYFDKCRIPGDRI
                                        :*: .* * ..  **       *:.::.* *:*: : .  :* .  

Mb0406c|M.bovis_AF2122/97           LPG-ATGLRAPLACLSEARYGIVWGAMGAARSAWQCALDYARQRTQFGRP
Rv0400c|M.tuberculosis_H37Rv        LPG-ATGLRAPLACLSEARYGIVWGAMGAARSAWQCALDYARQRTQFGRP
MMAR_0698|M.marinum_M               LPG-ATGVRGPLTCLSEARYGIVWGAMGAARSAWQCALDYAKERTQFGRP
MUL_2825|M.ulcerans_Agy99           LPG-ATGVRGPLTCLSEARYGIVWGAMGAARSAWQCALDYAKERTQFGRP
MAV_4767|M.avium_104                LPG-ATGLRGPLSCLSEARYGIIWGAMGAARSAWQAALDYATQRTQFGRP
TH_2172|M.thermoresistible__bu      LPG-ARGLSGPLACLSEARFGIVFGSVGAARDCLETTLDYVATREVFDKP
MSMEG_5267|M.smegmatis_MC2_155      LPN-ARGLSGPLACLSEARFGIVFGSVGAARDCLEATLDYVGTREVFDKT
Mvan_4671|M.vanbaalenii_PYR-1       LPE-AQGLKAPLSCLSEARFGIVFGAVGAARDCLQTTLDYVGTRAVFDRP
Mflv_4513|M.gilvum_PYR-GCK          LPE-AVGLSAPLSCLNEARFGIVFGALGAARDSLETTIAYTQTREVFDRP
MAB_4609c|M.abscessus_ATCC_199      LPL-AVGLKAPLSCLNEARFGIIFGSMGAARECLRTALEYAQTREQFDRP
MLBr_00737|M.leprae_Br4923          IGEPGTGFKTALATLDHTRPTIGAQAVGIAQGALDAAIVYTKDRKQFGES
                                    :   . *.  .*: *..:*  *   ::* *: .   :: *.  *  *...

Mb0406c|M.bovis_AF2122/97           IAGFQLTQAKLVDMAVELHKGQLLSLHLGRLKDRVGLRPDQVSFG-KLNN
Rv0400c|M.tuberculosis_H37Rv        IAGFQLTQAKLVDMAVELHKGQLLSLHLGRLKDRVGLRPDQVSFG-KLNN
MMAR_0698|M.marinum_M               IAGFQLTQAKLVDMAVELHKGQLLALQLGRLKDSVGLRPEQVSFG-KLNN
MUL_2825|M.ulcerans_Agy99           IAGFQLTQAKLVDMAVELHKGQLLALQLGRLKDSVGLRPEQVSFG-KLNN
MAV_4767|M.avium_104                IAGFQLTQAKLVDMAVELHKGQLLSLHLGRLKDSTGLRPEQVSFG-KLNN
TH_2172|M.thermoresistible__bu      LAGYQITQTKLADMAVELGKAQLLALHLGRLKDGGTIRPEQISVG-KLNN
MSMEG_5267|M.smegmatis_MC2_155      LASYQITQTKIADMAVELSKAQLLALHLGRLKDAGRISPEQVSVG-KLNN
Mvan_4671|M.vanbaalenii_PYR-1       LAGYQLTQAKIADMAVELGKAQLLALHLGRLKDEGRIRPEQVSVG-KLNN
Mflv_4513|M.gilvum_PYR-GCK          LAGYQLTQEKLANMTVELGKGMLLAIHLGRIKDAEGVRPEQVSLG-KLNN
MAB_4609c|M.abscessus_ATCC_199      IAGFQLTQEKLANMALEYGKGVLLALHLGRRKDADTLATPQVSLG-KLNN
MLBr_00737|M.leprae_Br4923          ISTFQSIQFMLADMAMKVEAARLIVYAAAARAERGEPDLGFISAASKCFA
                                    :: :*  *  :.:*:::   . *:    .   :        :* . *   

Mb0406c|M.bovis_AF2122/97           TREALKICRTARTILGGNGISLEYPVIRHMVNLESVLTYEGTPEMHQLVL
Rv0400c|M.tuberculosis_H37Rv        TREALKICRTARTILGGNGISLEYPVIRHMVNLESVLTYEGTPEMHQLVL
MMAR_0698|M.marinum_M               TREAIKICRTARTILGGNGISLEYPVIRHMVNLESVLTYEGTPEMHQLVL
MUL_2825|M.ulcerans_Agy99           TREAIKICRTARTILGGNGISLEYPVIRHMVNLESVLTYEGTPEMHQLVL
MAV_4767|M.avium_104                TREAIEICRTARTILGGNGISLEYPVIRHMVNLESVLTYEGTPEMHQLVL
TH_2172|M.thermoresistible__bu      VREALRIARECRTLLGANGVTLEYPVLRHANNLESVLTYEGTSEVHQLVI
MSMEG_5267|M.smegmatis_MC2_155      VREALEIARQCRTLLGANGITLEYPVLRHANNLESVLTYEGTSEVHQMVI
Mvan_4671|M.vanbaalenii_PYR-1       VREAIKIARQCRTLLGANGITLEYPVLRHANNLESVLTYEGTSEVHQLVI
Mflv_4513|M.gilvum_PYR-GCK          VREAIAIARECRTLLGGSGITLEYSPLRHANNLESVLTYEGTSEMHLLSI
MAB_4609c|M.abscessus_ATCC_199      VREAIEIARTARTILGANGISGEYPVMRHANNLESVLTYEGTSEMHTLVI
MLBr_00737|M.leprae_Br4923          SDIAMEVTTDAVQLFGGAGYTSDFPVERFMRDAKITQIYEGTNQIQRVVM
                                       *: :   .  ::*. * : ::.  *.  : : .  **** ::: : :

Mb0406c|M.bovis_AF2122/97           GQAFTGLAAFR-
Rv0400c|M.tuberculosis_H37Rv        GQAFTGLAAFR-
MMAR_0698|M.marinum_M               GQAFTGLAAFR-
MUL_2825|M.ulcerans_Agy99           GQAFTGLAAFR-
MAV_4767|M.avium_104                GQAFTGADAFR-
TH_2172|M.thermoresistible__bu      GQTMTGLSAFR-
MSMEG_5267|M.smegmatis_MC2_155      AQALTGVSAFR-
Mvan_4671|M.vanbaalenii_PYR-1       GEALTGVGAFR-
Mflv_4513|M.gilvum_PYR-GCK          GKALTGHAAFRA
MAB_4609c|M.abscessus_ATCC_199      GQALTGIAAFR-
MLBr_00737|M.leprae_Br4923          SRALLR------
                                    ..::

species	id	gene	e-value	identity (len)	annotation
M. thermoresistible (build 8)	TH_2172	-	-	100% (386)	glutaryl-CoA dehydrogenase
M. thermoresistible (build 8)	TH_2782	-	2e-50	33.51% (370)	PUTATIVE acyl-CoA dehydrogenase domain protein
M. thermoresistible (build 8)	TH_3610	-	5e-50	34.83% (379)	PUTATIVE acyl-CoA dehydrogenase domain protein