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M. abscessus ATCC 19977 MAB_0822 (-)

annotation: acyl-CoA dehydrogenase
coordinates: 816945 - 818138
length: 397

MSTAVTPSPEMCSTPLELFDTDRRLDQDERDIAATVRKFVDTKLRPNIAEWFESATLPRDLARQFGELGV
LGMHLDGYGCAGTNAVSYGLACLELEAGDSGLRSFVSVQGSLSMYSIHRYGSEEQKQEWLPQLASGHAIG
CFGLTEPDFGSNPGGMRTRARRDGKDWILDGTKMWITNGNLADVATVWAQTDDGVRGFVVPTATKGFAAN
VIHKKLSLRASVTSELVLDGVRLPDSAELPGARGLSAPLSCLNEARFGIVFGALGAARDSLQAALDYTRT
REVFGRPLSSYQLSQEKLANMTVQLGMGMLLALHLGRIKDSVGLRPEQVSLGKLNNVREALNIARECRTL
LGASGITLEYSPLRHANNLESVLTYEGTSEMHLLSIGRALTGQAAFR

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. abscessus ATCC 19977 MAB_0822 - - 100% (397) acyl-CoA dehydrogenase
M. abscessus ATCC 19977 MAB_4609c - e-146 65.28% (386) putative acyl-CoA dehydrogenase FadE
M. abscessus ATCC 19977 MAB_4538c - 7e-46 32.72% (379) putative acyl-CoA dehydrogenase FadE

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb0406c fadE7 1e-142 63.16% (399) acyl-CoA dehydrogenase FADE7
M. gilvum PYR-GCK Mflv_4513 - 0.0 80.80% (401) acyl-CoA dehydrogenase domain-containing protein
M. tuberculosis H37Rv Rv0400c fadE7 1e-142 63.16% (399) acyl-CoA dehydrogenase FADE7
M. leprae Br4923 MLBr_00737 fadE25 6e-41 30.65% (385) putative acyl-CoA dehydrogenase
M. marinum M MMAR_0698 fadE7 1e-145 63.66% (399) acyl-CoA dehydrogenase FadE7
M. avium 104 MAV_4767 - 1e-145 66.05% (377) putative acyl-CoA dehydrogenase
M. smegmatis MC2 155 MSMEG_6686 - 0.0 82.78% (395) glutaryl-CoA dehydrogenase
M. thermoresistible (build 8) TH_2172 - 1e-151 67.36% (383) glutaryl-CoA dehydrogenase
M. ulcerans Agy99 MUL_2825 fadE7 1e-145 63.66% (399) acyl-CoA dehydrogenase FadE7
M. vanbaalenii PYR-1 Mvan_1857 - 0.0 81.55% (401) acyl-CoA dehydrogenase domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


Mb0406c|M.bovis_AF2122/97           ----MSTPTPPALDRDDPLGLDASLSSDEIAVRDTVRRFCAEHVTPHVAA
Rv0400c|M.tuberculosis_H37Rv        ----MSTPTPPALDRDDPLGLDASLSSDEIAVRDTVRRFCAEHVTPHVAA
MMAR_0698|M.marinum_M               ----MSTETPPTFDPHDPLGLDASLSDDEIAVRDTVRKFCAEHITAHVAE
MUL_2825|M.ulcerans_Agy99           ----MSTETPPTFDPHDPLGLDASLSDDEIAVRDTVRKFCAEHITAHVAE
MAV_4767|M.avium_104                MSTETSTKTPPAFDRYDPLGLDALLSDDERAVRDTVRGFCAEHVLPHVAE
Mflv_4513|M.gilvum_PYR-GCK          MSTTTAPATKAVYAPLELFDTARLLEQDEREIAATVRKFVDSELKPNVED
Mvan_1857|M.vanbaalenii_PYR-1       -MTTTAAPQKAVYSPLELFDTARLLDHDEREIAATVRKFVDTELKPNIEG
MSMEG_6686|M.smegmatis_MC2_155      -MTLTAPSKKSTYAPLELFDTDRLLDQDERDIAATVRQFVDTRLKPNVEG
MAB_0822|M.abscessus_ATCC_1997      MSTAVTPSPEMCSTPLELFDTDRRLDQDERDIAATVRKFVDTKLRPNIAE
TH_2172|M.thermoresistible__bu      --------------VDDLLDLDALLTPEDIELRDTVRRFGEQRLRPHVAD
MLBr_00737|M.leprae_Br4923          ---------MVGWSGNPLFDLFKLPEEHN-ELRATIRALAEKEIAPHAAD
                                                      :.       .:  :  *:* :   .: .:   

Mb0406c|M.bovis_AF2122/97           WFEDGDLPVARDLAKQFGELGLLGMQL-HGHGCGGASAVHYGLACRELEA
Rv0400c|M.tuberculosis_H37Rv        WFEDGDLPVARDLAKQFGELGLLGMQL-HGHGCGGASAVHYGLACRELEA
MMAR_0698|M.marinum_M               WFENGDLPAARDLAKQLGGLGLLGMHL-QGYGCGGASAVHYGLACLELEA
MUL_2825|M.ulcerans_Agy99           WFENGDLPAARDLAKQLGGLGLLGMHL-QGYGCGGASAVHYGLACLELEA
MAV_4767|M.avium_104                WFEIGDLP-VRELAREFGRLGLLGMHL-HGYGCGGASAVHYGLACVELEA
Mflv_4513|M.gilvum_PYR-GCK          WFESATLP--KELGKRFGELGLLGMHL-QGYGCAGTNAVSYGLACMELEA
Mvan_1857|M.vanbaalenii_PYR-1       WFESSTLP--RELGRRFGELGVLGMHL-EGYGCAGTNAVSYGLACLELEA
MSMEG_6686|M.smegmatis_MC2_155      WFESATLP--SELAKEFGNLGVLGMHL-QGYGCAGTNAVSYGLACMELEA
MAB_0822|M.abscessus_ATCC_1997      WFESATLP--RDLARQFGELGVLGMHL-DGYGCAGTNAVSYGLACLELEA
TH_2172|M.thermoresistible__bu      WFESGQIP-VRELAADLGKLGLLGMHL-QGYGCSGSTATAYGLVCQELEA
MLBr_00737|M.leprae_Br4923          VDQRARFP--EEALAALNASGFNAIHVPEEYGGQGADSVAACIVIEEVAR
                                      : . :*   :    :.  *. .::: . :*  *: :.   :.  *:  

Mb0406c|M.bovis_AF2122/97           ADSGIRSLVSVQGSLAMFAIASFGSDEQKRQWLPGMATGDLLGCFGLTEP
Rv0400c|M.tuberculosis_H37Rv        ADSGIRSLVSVQGSLAMFAIASFGSDEQKRQWLPGMATGDLLGCFGLTEP
MMAR_0698|M.marinum_M               ADSGIRSLVSVQGSLAMFAIAHFGSEEHKQRWLPPMAAGELIGCFGLTEP
MUL_2825|M.ulcerans_Agy99           ADSGIRSLVSVQGSLAMFAIAHFGSEEHKQRWLPPMAAGELIGCFGLTEP
MAV_4767|M.avium_104                ADSGLRSMVSVQGSLAMFAIWNFGSEEQKRQWLPGMATGEMLGCFGLTEP
Mflv_4513|M.gilvum_PYR-GCK          GDSGFRSFVSVQGSLSMFSIHRYGSEEQKNEWLPRLASGDAIGCFGLTEP
Mvan_1857|M.vanbaalenii_PYR-1       GDSGFRSFVSVQGSLSMYSIYRYGSDEQKNEWLPQLASGEAIGCFGLTEP
MSMEG_6686|M.smegmatis_MC2_155      GDSGFRSFVSVQGSLSMFSIYRYGSEEQKNEWLPRLAAGDAIGCFGLTEP
MAB_0822|M.abscessus_ATCC_1997      GDSGLRSFVSVQGSLSMYSIHRYGSEEQKQEWLPQLASGHAIGCFGLTEP
TH_2172|M.thermoresistible__bu      VDSGLRSLVSVQGSLAMFAIYRHGSEEQRRHWLPPMATGEVIGCFGLTEP
MLBr_00737|M.leprae_Br4923          VDASASLIPAVN-KLGTMGLILRGSEELKKQVLPSLAAEGAMASYALSER
                                     *:.   : :*: .*.  .:   **:* :.. ** :*:   :..:.*:* 

Mb0406c|M.bovis_AF2122/97           DVGSDPAAMKTRARRDGP----DWVITGGKMWITNGSVADVAIVWAA---
Rv0400c|M.tuberculosis_H37Rv        DVGSDPAAMKTRARRDGP----DWVITGGKMWITNGSVADVAIVWAA---
MMAR_0698|M.marinum_M               DVGSDPAAMKTRARRDGS----DWVLNGRKMWITNGSIADVAIVWAA---
MUL_2825|M.ulcerans_Agy99           DVGSDPAAMKTRARRDGS----DWVLNGRKMWITNGSIADVAIVWAA---
MAV_4767|M.avium_104                DVGSDPAAMKTRARRDGS----DWVLDGRKLWITNGSVADVAVVWAG---
Mflv_4513|M.gilvum_PYR-GCK          DFGSNPAGMRTRGKRDGSGENADWILNGTKMWITNGNLADVATVWAQ---
Mvan_1857|M.vanbaalenii_PYR-1       DFGSNPAGMRTRARRSGAGENADWVLNGTKMWITNGNLADVATVWAQ---
MSMEG_6686|M.smegmatis_MC2_155      DFGSNPAGMRTRARRDGS----DWILNGTKMWITNGNLADVATVWAQ---
MAB_0822|M.abscessus_ATCC_1997      DFGSNPGGMRTRARRDGK----DWILDGTKMWITNGNLADVATVWAQ---
TH_2172|M.thermoresistible__bu      DFGSNPAGMRTTARRDGS----DWILNGSKMWITNGSVADVAIVWARS--
MLBr_00737|M.leprae_Br4923          EAGSDAASMRTRAKADGD----DWILNGFKCWITNGGKSTWYTVMAVTDP
                                    : **:...*:* .: .*     **:: * * *****. :    * *    

Mb0406c|M.bovis_AF2122/97           --TDDGIRGFIVPTDTPGFTANTIGHKLSLRASITSELVLDNVRLPADAM
Rv0400c|M.tuberculosis_H37Rv        --TDDGIRGFIVPTDTPGFTANTIGHKLSLRASITSELVLDNVRLPADAM
MMAR_0698|M.marinum_M               --TEEGIRGFVVPTETAGFAANTIHHKLSLRASITSELVLDDVRLPAEAM
MUL_2825|M.ulcerans_Agy99           --TEEGIRGFVVPTETAGFAANTIHHKLSLRASITSELVLDDVRLPAEAM
MAV_4767|M.avium_104                --TDDGIRGFLVPTDTPGFTANTIHHKLSLRASITSELVLDDVRLPGEAM
Mflv_4513|M.gilvum_PYR-GCK          --TDEGIRGFLVPTDTPGFTANAIHRKLSLRASITSELVLDNVRLPASAQ
Mvan_1857|M.vanbaalenii_PYR-1       --TDEGIRGFLVPTDTPGFTANAIHRKLSLRASVTSELVLDNVRLPASAQ
MSMEG_6686|M.smegmatis_MC2_155      --TDDGIRGFLVPTDTPGFTANEIHRKLSLRASVTSELVLDNVRLPASAQ
MAB_0822|M.abscessus_ATCC_1997      --TDDGVRGFVVPTATKGFAANVIHKKLSLRASVTSELVLDGVRLPDSAE
TH_2172|M.thermoresistible__bu      --ADDGILGFVVPTDTPGFTAREMTRKLSLRASVTSELHLDDVRLPADAR
MLBr_00737|M.leprae_Br4923          DKGANGISAFIVHKDDEGFSIGPKEKKLGIKGSPTTELYFDKCRIPGDRI
                                        :*: .*:* .   **:     :**.::.* *:** :*  *:* .  

Mb0406c|M.bovis_AF2122/97           LPG-ATGLRAPLACLSEARYGIVWGAMGAARSAWQCALDYARQRTQFGRP
Rv0400c|M.tuberculosis_H37Rv        LPG-ATGLRAPLACLSEARYGIVWGAMGAARSAWQCALDYARQRTQFGRP
MMAR_0698|M.marinum_M               LPG-ATGVRGPLTCLSEARYGIVWGAMGAARSAWQCALDYAKERTQFGRP
MUL_2825|M.ulcerans_Agy99           LPG-ATGVRGPLTCLSEARYGIVWGAMGAARSAWQCALDYAKERTQFGRP
MAV_4767|M.avium_104                LPG-ATGLRGPLSCLSEARYGIIWGAMGAARSAWQAALDYATQRTQFGRP
Mflv_4513|M.gilvum_PYR-GCK          LPE-AVGLSAPLSCLNEARFGIVFGALGAARDSLETTIAYTQTREVFDRP
Mvan_1857|M.vanbaalenii_PYR-1       LPD-AVGLSAPLSCLNEARFGIVFGALGAARDSLETTIAYTQTRDVFDKP
MSMEG_6686|M.smegmatis_MC2_155      LPL-AEGLSAPLSCLNEARFGIVFGALGAARDSLETTIAYTQSREVFDKP
MAB_0822|M.abscessus_ATCC_1997      LPG-ARGLSAPLSCLNEARFGIVFGALGAARDSLQAALDYTRTREVFGRP
TH_2172|M.thermoresistible__bu      LPG-ARGLSGPLACLSEARFGIVFGSVGAARDCLETTLDYVATREVFDKP
MLBr_00737|M.leprae_Br4923          IGEPGTGFKTALATLDHTRPTIGAQAVGIAQGALDAAIVYTKDRKQFGES
                                    :   . *.  .*: *..:*  *   ::* *:.. : :: *.  *  *...

Mb0406c|M.bovis_AF2122/97           IAGFQLTQAKLVDMAVELHKGQLLSLHLGRLKDRVGLRPDQVSFG-KLNN
Rv0400c|M.tuberculosis_H37Rv        IAGFQLTQAKLVDMAVELHKGQLLSLHLGRLKDRVGLRPDQVSFG-KLNN
MMAR_0698|M.marinum_M               IAGFQLTQAKLVDMAVELHKGQLLALQLGRLKDSVGLRPEQVSFG-KLNN
MUL_2825|M.ulcerans_Agy99           IAGFQLTQAKLVDMAVELHKGQLLALQLGRLKDSVGLRPEQVSFG-KLNN
MAV_4767|M.avium_104                IAGFQLTQAKLVDMAVELHKGQLLSLHLGRLKDSTGLRPEQVSFG-KLNN
Mflv_4513|M.gilvum_PYR-GCK          LAGYQLTQEKLANMTVELGKGMLLAIHLGRIKDAEGVRPEQVSLG-KLNN
Mvan_1857|M.vanbaalenii_PYR-1       LAGYQLTQEKLANMTVELGKGMLLAIHLGRIKDAEGVRPEQISLG-KLNN
MSMEG_6686|M.smegmatis_MC2_155      LSNYQLTQEKLANMTVELGKGMLLAIHLGRIKDAEGVRPEQISLG-KLNN
MAB_0822|M.abscessus_ATCC_1997      LSSYQLSQEKLANMTVQLGMGMLLALHLGRIKDSVGLRPEQVSLG-KLNN
TH_2172|M.thermoresistible__bu      LAGYQITQTKLADMAVELGKAQLLALHLGRLKDGGTIRPEQISVG-KLNN
MLBr_00737|M.leprae_Br4923          ISTFQSIQFMLADMAMKVEAARLIVYAAAARAERGEPDLGFISAASKCFA
                                    :: :*  *  *.:*::::  . *:    .   :        :* . *   

Mb0406c|M.bovis_AF2122/97           TREALKICRTARTILGGNGISLEYPVIRHMVNLESVLTYEGTPEMHQLVL
Rv0400c|M.tuberculosis_H37Rv        TREALKICRTARTILGGNGISLEYPVIRHMVNLESVLTYEGTPEMHQLVL
MMAR_0698|M.marinum_M               TREAIKICRTARTILGGNGISLEYPVIRHMVNLESVLTYEGTPEMHQLVL
MUL_2825|M.ulcerans_Agy99           TREAIKICRTARTILGGNGISLEYPVIRHMVNLESVLTYEGTPEMHQLVL
MAV_4767|M.avium_104                TREAIEICRTARTILGGNGISLEYPVIRHMVNLESVLTYEGTPEMHQLVL
Mflv_4513|M.gilvum_PYR-GCK          VREAIAIARECRTLLGGSGITLEYSPLRHANNLESVLTYEGTSEMHLLSI
Mvan_1857|M.vanbaalenii_PYR-1       VREAIAIARECRTLLGGSGITLEYSPLRHANNLESVLTYEGTSEMHLLSI
MSMEG_6686|M.smegmatis_MC2_155      VREAIAIARECRTLLGGSGITLEYSPLRHANNLESVLTYEGTSEMHLLSI
MAB_0822|M.abscessus_ATCC_1997      VREALNIARECRTLLGASGITLEYSPLRHANNLESVLTYEGTSEMHLLSI
TH_2172|M.thermoresistible__bu      VREALRIARECRTLLGANGVTLEYPVLRHANNLESVLTYEGTSEVHQLVI
MLBr_00737|M.leprae_Br4923          SDIAMEVTTDAVQLFGGAGYTSDFPVERFMRDAKITQIYEGTNQIQRVVM
                                       *: :   .  ::*. * : ::.  *.  : : .  **** ::: : :

Mb0406c|M.bovis_AF2122/97           GQAFTGLAAFR-
Rv0400c|M.tuberculosis_H37Rv        GQAFTGLAAFR-
MMAR_0698|M.marinum_M               GQAFTGLAAFR-
MUL_2825|M.ulcerans_Agy99           GQAFTGLAAFR-
MAV_4767|M.avium_104                GQAFTGADAFR-
Mflv_4513|M.gilvum_PYR-GCK          GKALTGHAAFRA
Mvan_1857|M.vanbaalenii_PYR-1       GKALTGHAAFRS
MSMEG_6686|M.smegmatis_MC2_155      GKALTGKAAFRS
MAB_0822|M.abscessus_ATCC_1997      GRALTGQAAFR-
TH_2172|M.thermoresistible__bu      GQTMTGLSAFR-
MLBr_00737|M.leprae_Br4923          SRALLR------
                                    .:::

species	id	gene	e-value	identity (len)	annotation
M. abscessus ATCC 19977	MAB_0822	-	-	100% (397)	acyl-CoA dehydrogenase
M. abscessus ATCC 19977	MAB_4609c	-	e-146	65.28% (386)	putative acyl-CoA dehydrogenase FadE
M. abscessus ATCC 19977	MAB_4538c	-	7e-46	32.72% (379)	putative acyl-CoA dehydrogenase FadE