For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
STETPPTFDPHDPLGLDASLSDDEIAVRDTVRKFCAEHITAHVAEWFENGDLPAARDLAKQLGGLGLLGM HLQGYGCGGASAVHYGLACLELEAADSGIRSLVSVQGSLAMFAIAHFGSEEHKQRWLPPMAAGELIGCFG LTEPDVGSDPAAMKTRARRDGSDWVLNGRKMWITNGSIADVAIVWAATEEGIRGFVVPTETAGFAANTIH HKLSLRASITSELVLDDVRLPAEAMLPGATGVRGPLTCLSEARYGIVWGAMGAARSAWQCALDYAKERTQ FGRPIAGFQLTQAKLVDMAVELHKGQLLALQLGRLKDSVGLRPEQVSFGKLNNTREAIKICRTARTILGG NGISLEYPVIRHMVNLESVLTYEGTPEMHQLVLGQAFTGLAAFR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_0698 | fadE7 | - | 100% (395) | acyl-CoA dehydrogenase FadE7 |
| M. marinum M | MMAR_0149 | fadE25_2 | 3e-50 | 37.19% (398) | acyl-CoA dehydrogenase FadE25_2 |
| M. marinum M | MMAR_4034 | fadE | 1e-44 | 34.62% (338) | acyl-CoA dehydrogenase FadE |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0406c | fadE7 | 0.0 | 87.09% (395) | acyl-CoA dehydrogenase FADE7 |
| M. gilvum PYR-GCK | Mflv_4513 | - | 1e-141 | 62.28% (403) | acyl-CoA dehydrogenase domain-containing protein |
| M. tuberculosis H37Rv | Rv0400c | fadE7 | 0.0 | 87.09% (395) | acyl-CoA dehydrogenase FADE7 |
| M. leprae Br4923 | MLBr_00737 | fadE25 | 1e-42 | 31.13% (379) | putative acyl-CoA dehydrogenase |
| M. abscessus ATCC 19977 | MAB_4609c | - | 1e-146 | 65.06% (395) | putative acyl-CoA dehydrogenase FadE |
| M. avium 104 | MAV_4767 | - | 0.0 | 86.04% (394) | putative acyl-CoA dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_2466 | - | 1e-148 | 68.67% (383) | glutaryl-CoA dehydrogenase |
| M. thermoresistible (build 8) | TH_2172 | - | 1e-150 | 67.45% (384) | glutaryl-CoA dehydrogenase |
| M. ulcerans Agy99 | MUL_2825 | fadE7 | 0.0 | 100.00% (395) | acyl-CoA dehydrogenase FadE7 |
| M. vanbaalenii PYR-1 | Mvan_4671 | - | 1e-145 | 65.38% (390) | acyl-CoA dehydrogenase domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0698|M.marinum_M ----MSTETPPTFDP--HDPLGLDASLSDDEIAVRDTVRKFCAEHITAHV
MUL_2825|M.ulcerans_Agy99 ----MSTETPPTFDP--HDPLGLDASLSDDEIAVRDTVRKFCAEHITAHV
Mb0406c|M.bovis_AF2122/97 ----MSTPTPPALDR--DDPLGLDASLSSDEIAVRDTVRRFCAEHVTPHV
Rv0400c|M.tuberculosis_H37Rv ----MSTPTPPALDR--DDPLGLDASLSSDEIAVRDTVRRFCAEHVTPHV
MAV_4767|M.avium_104 MSTETSTKTPPAFDR--YDPLGLDALLSDDERAVRDTVRGFCAEHVLPHV
TH_2172|M.thermoresistible__bu ------------VD----DLLDLDALLTPEDIELRDTVRRFGEQRLRPHV
Mvan_4671|M.vanbaalenii_PYR-1 MPAHQPLPTTTTIE----NLLDLDSLLSAEDRDLRTMVRGFGEQRLRPQI
Mflv_4513|M.gilvum_PYR-GCK MSTTTAPATKAVYAP--LELFDTARLLEQDEREIAATVRKFVDSELKPNV
MAB_4609c|M.abscessus_ATCC_199 MATDAAPTNP-------DELFGIDALLSDEERAIRDSVRALVQARVVPNV
MSMEG_2466|M.smegmatis_MC2_155 -MTNSAVAQPRSQRRGADDLIGINAVLSAEEREIRDTVRSVVQRRIKPHI
MLBr_00737|M.leprae_Br4923 ------------MVGWSGNPLFDLFKLPEEHNELRATIRALAEKEIAPHA
: : * :. : :* . .: .:
MMAR_0698|M.marinum_M AEWFENGDLPAARDLAKQLGGLGLLGMHL-QGYGCGGASAVHYGLACLEL
MUL_2825|M.ulcerans_Agy99 AEWFENGDLPAARDLAKQLGGLGLLGMHL-QGYGCGGASAVHYGLACLEL
Mb0406c|M.bovis_AF2122/97 AAWFEDGDLPVARDLAKQFGELGLLGMQL-HGHGCGGASAVHYGLACREL
Rv0400c|M.tuberculosis_H37Rv AAWFEDGDLPVARDLAKQFGELGLLGMQL-HGHGCGGASAVHYGLACREL
MAV_4767|M.avium_104 AEWFEIGDLP-VRELAREFGRLGLLGMHL-HGYGCGGASAVHYGLACVEL
TH_2172|M.thermoresistible__bu ADWFESGQIP-VRELAADLGKLGLLGMHL-QGYGCSGSTATAYGLVCQEL
Mvan_4671|M.vanbaalenii_PYR-1 AEWFEAGQVP-VRELAAEIGKLGLLGMHL-QGYGCSGSTATAYGLVCQEL
Mflv_4513|M.gilvum_PYR-GCK EDWFESATLP--KELGKRFGELGLLGMHL-QGYGCAGTNAVSYGLACMEL
MAB_4609c|M.abscessus_ATCC_199 QRWYEHGDLP-VRKLALELGKIGVLGMHL-HGYGCSGTSSLAYGLACMEL
MSMEG_2466|M.smegmatis_MC2_155 ASWYEDGELP-ARELAVELGELGLLGMHL-KGYGCAGMSAVAYGLACLEL
MLBr_00737|M.leprae_Br4923 ADVDQRARFP--EEALAALNASGFNAIHVPEEYGGQGADSVAACIVIEEV
: . .* .. :. *. .::: . :* * : :. *:
MMAR_0698|M.marinum_M EAADSGIRSLVSVQGSLAMFAIAHFGSEEHKQRWLPPMAAGELIGCFGLT
MUL_2825|M.ulcerans_Agy99 EAADSGIRSLVSVQGSLAMFAIAHFGSEEHKQRWLPPMAAGELIGCFGLT
Mb0406c|M.bovis_AF2122/97 EAADSGIRSLVSVQGSLAMFAIASFGSDEQKRQWLPGMATGDLLGCFGLT
Rv0400c|M.tuberculosis_H37Rv EAADSGIRSLVSVQGSLAMFAIASFGSDEQKRQWLPGMATGDLLGCFGLT
MAV_4767|M.avium_104 EAADSGLRSMVSVQGSLAMFAIWNFGSEEQKRQWLPGMATGEMLGCFGLT
TH_2172|M.thermoresistible__bu EAVDSGLRSLVSVQGSLAMFAIYRHGSEEQRRHWLPPMATGEVIGCFGLT
Mvan_4671|M.vanbaalenii_PYR-1 EAVDSGLRSLVSVQGSLAMFAIHRWGSEEQRTRWLPGMAAGELIGCFGLT
Mflv_4513|M.gilvum_PYR-GCK EAGDSGFRSFVSVQGSLSMFSIHRYGSEEQKNEWLPRLASGDAIGCFGLT
MAB_4609c|M.abscessus_ATCC_199 EAGDSGIRSLVSVQGSLAMYAIYAYGSDAQKQKWLPRMATGEELGCFGLT
MSMEG_2466|M.smegmatis_MC2_155 EAGDSGIRSLVSVQGSLAMYAIHAFGSDEQKDQWLPDMASGHRIGCFGLT
MLBr_00737|M.leprae_Br4923 ARVDASASLIPAVN-KLGTMGLILRGSEELKKQVLPSLAAEGAMASYALS
*:. : :*: .*. .: **: : . ** :*: :..:.*:
MMAR_0698|M.marinum_M EPDVGSDPAAMKTRARRDGS----DWVLNGRKMWITNGSIADVAIVWAAT
MUL_2825|M.ulcerans_Agy99 EPDVGSDPAAMKTRARRDGS----DWVLNGRKMWITNGSIADVAIVWAAT
Mb0406c|M.bovis_AF2122/97 EPDVGSDPAAMKTRARRDGP----DWVITGGKMWITNGSVADVAIVWAAT
Rv0400c|M.tuberculosis_H37Rv EPDVGSDPAAMKTRARRDGP----DWVITGGKMWITNGSVADVAIVWAAT
MAV_4767|M.avium_104 EPDVGSDPAAMKTRARRDGS----DWVLDGRKLWITNGSVADVAVVWAGT
TH_2172|M.thermoresistible__bu EPDFGSNPAGMRTTARRDGS----DWILNGSKMWITNGSVADVAIVWARS
Mvan_4671|M.vanbaalenii_PYR-1 EPDFGSNPGGMRTTARRDGS----DWILNGSKMWITNASVADVAIIWARS
Mflv_4513|M.gilvum_PYR-GCK EPDFGSNPAGMRTRGKRDGSGENADWILNGTKMWITNGNLADVATVWAQT
MAB_4609c|M.abscessus_ATCC_199 EPDFGSNPGGMRTHARRDGS----DWVLNGTKMWITNGSIADVAVIWAQT
MSMEG_2466|M.smegmatis_MC2_155 EPDHGSDPAGMRTRATRSGD----DWILTGTKMWITNGSVADVAVVWART
MLBr_00737|M.leprae_Br4923 EREAGSDAASMRTRAKADGD----DWILNGFKCWITNGGKSTWYTVMAVT
* : **:...*:* . .* **:: * * ****.. : : * :
MMAR_0698|M.marinum_M EE-----GIRGFVVPTETAGFAANTIHHKLSLRASITSELVLDDVRLPAE
MUL_2825|M.ulcerans_Agy99 EE-----GIRGFVVPTETAGFAANTIHHKLSLRASITSELVLDDVRLPAE
Mb0406c|M.bovis_AF2122/97 DD-----GIRGFIVPTDTPGFTANTIGHKLSLRASITSELVLDNVRLPAD
Rv0400c|M.tuberculosis_H37Rv DD-----GIRGFIVPTDTPGFTANTIGHKLSLRASITSELVLDNVRLPAD
MAV_4767|M.avium_104 DD-----GIRGFLVPTDTPGFTANTIHHKLSLRASITSELVLDDVRLPGE
TH_2172|M.thermoresistible__bu ADD----GILGFVVPTDTPGFTAREMTRKLSLRASVTSELHLDDVRLPAD
Mvan_4671|M.vanbaalenii_PYR-1 KE-----GVLGFAVPTSTPGFHATEMTRKLSLRASVTSEIHLDDVRVPED
Mflv_4513|M.gilvum_PYR-GCK DE-----GIRGFLVPTDTPGFTANAIHRKLSLRASITSELVLDNVRLPAS
MAB_4609c|M.abscessus_ATCC_199 DE-----GVRGFLVSTDSAGFDAQTIHSKMSLRASVTAELNLVDVWVPEK
MSMEG_2466|M.smegmatis_MC2_155 DE-----GIRGFVVPTDTPGFTANTIKSKMSLRASVTSELVLDGVRLPDS
MLBr_00737|M.leprae_Br4923 DPDKGANGISAFIVHKDDEGFSIGPKEKKLGIKGSPTTELYFDKCRIPGD
*: .* * .. ** *:.::.* *:*: : :* .
MMAR_0698|M.marinum_M AMLPG-ATGVRGPLTCLSEARYGIVWGAMGAARSAWQCALDYAKERTQFG
MUL_2825|M.ulcerans_Agy99 AMLPG-ATGVRGPLTCLSEARYGIVWGAMGAARSAWQCALDYAKERTQFG
Mb0406c|M.bovis_AF2122/97 AMLPG-ATGLRAPLACLSEARYGIVWGAMGAARSAWQCALDYARQRTQFG
Rv0400c|M.tuberculosis_H37Rv AMLPG-ATGLRAPLACLSEARYGIVWGAMGAARSAWQCALDYARQRTQFG
MAV_4767|M.avium_104 AMLPG-ATGLRGPLSCLSEARYGIIWGAMGAARSAWQAALDYATQRTQFG
TH_2172|M.thermoresistible__bu ARLPG-ARGLSGPLACLSEARFGIVFGSVGAARDCLETTLDYVATREVFD
Mvan_4671|M.vanbaalenii_PYR-1 ARLPE-AQGLKAPLSCLSEARFGIVFGAVGAARDCLQTTLDYVGTRAVFD
Mflv_4513|M.gilvum_PYR-GCK AQLPE-AVGLSAPLSCLNEARFGIVFGALGAARDSLETTIAYTQTREVFD
MAB_4609c|M.abscessus_ATCC_199 NRLPL-AVGLKAPLSCLNEARFGIIFGSMGAARECLRTALEYAQTREQFD
MSMEG_2466|M.smegmatis_MC2_155 ARLPG-ATSLGAPLRCLNEARFGIVFGALGAARDCLETALAYACSREQFD
MLBr_00737|M.leprae_Br4923 RIIGEPGTGFKTALATLDHTRPTIGAQAVGIAQGALDAAIVYTKDRKQFG
: . .. .* *..:* * ::* *: . :: *. * *.
MMAR_0698|M.marinum_M RPIAGFQLTQAKLVDMAVELHKGQLLALQLGRLKDSVGLRPEQVSFG-KL
MUL_2825|M.ulcerans_Agy99 RPIAGFQLTQAKLVDMAVELHKGQLLALQLGRLKDSVGLRPEQVSFG-KL
Mb0406c|M.bovis_AF2122/97 RPIAGFQLTQAKLVDMAVELHKGQLLSLHLGRLKDRVGLRPDQVSFG-KL
Rv0400c|M.tuberculosis_H37Rv RPIAGFQLTQAKLVDMAVELHKGQLLSLHLGRLKDRVGLRPDQVSFG-KL
MAV_4767|M.avium_104 RPIAGFQLTQAKLVDMAVELHKGQLLSLHLGRLKDSTGLRPEQVSFG-KL
TH_2172|M.thermoresistible__bu KPLAGYQITQTKLADMAVELGKAQLLALHLGRLKDGGTIRPEQISVG-KL
Mvan_4671|M.vanbaalenii_PYR-1 RPLAGYQLTQAKIADMAVELGKAQLLALHLGRLKDEGRIRPEQVSVG-KL
Mflv_4513|M.gilvum_PYR-GCK RPLAGYQLTQEKLANMTVELGKGMLLAIHLGRIKDAEGVRPEQVSLG-KL
MAB_4609c|M.abscessus_ATCC_199 RPIAGFQLTQEKLANMALEYGKGVLLALHLGRRKDADTLATPQVSLG-KL
MSMEG_2466|M.smegmatis_MC2_155 RPIGGFQLTQQKLADMTLEYGKGFLLALHLGRQKDAGELAPEQVSLG-KL
MLBr_00737|M.leprae_Br4923 ESISTFQSIQFMLADMAMKVEAARLIVYAAAARAERGEPDLGFISAASKC
..:. :* * :.:*::: . *: . : :* . *
MMAR_0698|M.marinum_M NNTREAIKICRTARTILGGNGISLEYPVIRHMVNLESVLTYEGTPEMHQL
MUL_2825|M.ulcerans_Agy99 NNTREAIKICRTARTILGGNGISLEYPVIRHMVNLESVLTYEGTPEMHQL
Mb0406c|M.bovis_AF2122/97 NNTREALKICRTARTILGGNGISLEYPVIRHMVNLESVLTYEGTPEMHQL
Rv0400c|M.tuberculosis_H37Rv NNTREALKICRTARTILGGNGISLEYPVIRHMVNLESVLTYEGTPEMHQL
MAV_4767|M.avium_104 NNTREAIEICRTARTILGGNGISLEYPVIRHMVNLESVLTYEGTPEMHQL
TH_2172|M.thermoresistible__bu NNVREALRIARECRTLLGANGVTLEYPVLRHANNLESVLTYEGTSEVHQL
Mvan_4671|M.vanbaalenii_PYR-1 NNVREAIKIARQCRTLLGANGITLEYPVLRHANNLESVLTYEGTSEVHQL
Mflv_4513|M.gilvum_PYR-GCK NNVREAIAIARECRTLLGGSGITLEYSPLRHANNLESVLTYEGTSEMHLL
MAB_4609c|M.abscessus_ATCC_199 NNVREAIEIARTARTILGANGISGEYPVMRHANNLESVLTYEGTSEMHTL
MSMEG_2466|M.smegmatis_MC2_155 NNVREAIEIARTARTVLGASGITGEYPVMRHANNLESVLTYEGTSEMHTL
MLBr_00737|M.leprae_Br4923 FASDIAMEVTTDAVQLFGGAGYTSDFPVERFMRDAKITQIYEGTNQIQRV
*: : . ::*. * : ::. *. : : . **** ::: :
MMAR_0698|M.marinum_M VLGQAFTGLAAFR-
MUL_2825|M.ulcerans_Agy99 VLGQAFTGLAAFR-
Mb0406c|M.bovis_AF2122/97 VLGQAFTGLAAFR-
Rv0400c|M.tuberculosis_H37Rv VLGQAFTGLAAFR-
MAV_4767|M.avium_104 VLGQAFTGADAFR-
TH_2172|M.thermoresistible__bu VIGQTMTGLSAFR-
Mvan_4671|M.vanbaalenii_PYR-1 VIGEALTGVGAFR-
Mflv_4513|M.gilvum_PYR-GCK SIGKALTGHAAFRA
MAB_4609c|M.abscessus_ATCC_199 VIGQALTGIAAFR-
MSMEG_2466|M.smegmatis_MC2_155 IIGQALTGVGAFR-
MLBr_00737|M.leprae_Br4923 VMSRALLR------
:..::