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MLAAVAESQSAADPLAGLVLKDLPIPTPPSGWSVVRVVSSSLNMHDLWTLRGVGHPADRLPIVLGCDAAG FDQDGNEVIVYPVIANPDAGMGDETLDPDRALLSERHDGAFAEYLTVPTRNLVPKPAWLSFDEAACLPVA WTTAYRMLFTHAKITAGARVLVQGVGGGVASAAIRLASAAGAVVYATSRSEAKRQTAISWGARDAYATGE RLPERVDVVIETVGEATWSHSLKSLRPGGCIVIAGATTGMNPPADLGRVFYLQQRILGSTGCTRSELIAM LRMLDATGIRPVIDRTMPLAEIHKAFQLMIDGGLTGKLVIHPDPN
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4371 | - | - | 100% (325) | putative alcohol dehydrogenase |
| M. abscessus ATCC 19977 | MAB_4603c | - | 2e-20 | 26.13% (333) | oxidoreductase |
| M. abscessus ATCC 19977 | MAB_3307c | - | 2e-18 | 28.40% (324) | putative zinc-binding oxidoreductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3806 | - | 2e-20 | 24.49% (343) | putative oxidoreductase |
| M. gilvum PYR-GCK | Mflv_1189 | - | 2e-20 | 25.00% (332) | alcohol dehydrogenase |
| M. tuberculosis H37Rv | Rv3777 | - | 5e-20 | 24.20% (343) | oxidoreductase |
| M. leprae Br4923 | MLBr_00118 | - | 1e-23 | 25.22% (341) | putative oxidireductase |
| M. marinum M | MMAR_1738 | - | 8e-24 | 31.00% (300) | oxidoreductase |
| M. avium 104 | MAV_0308 | - | 3e-19 | 30.22% (321) | alcohol dehydrogenase, zinc-binding |
| M. smegmatis MC2 155 | MSMEG_4442 | - | 1e-23 | 31.56% (301) | zinc-binding oxidoreductase |
| M. thermoresistible (build 8) | TH_2475 | - | 5e-32 | 36.47% (266) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_0096 | - | 3e-22 | 26.44% (329) | oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_5758 | - | 2e-21 | 30.15% (325) | alcohol dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3806|M.bovis_AF2122/97 ---MTIMRAVVAESSDRLVWQEVPDVSAGPGEVLIKVAASGVNRADVLQA
Rv3777|M.tuberculosis_H37Rv ---MTIMRAVVAESSDRLVWQEVPDVSAGPGEVLIKVAASGVNRADVLQA
MUL_0096|M.ulcerans_Agy99 ---MAFVHAIVAESADHLVWQQVPDVTAGAGEVVIKVAAAGVNRADVLQA
MLBr_00118|M.leprae_Br4923 ------MHAIVAESANQMVWREVPDVTAGPGEVLIEVAASGVNRADVLQV
Mflv_1189|M.gilvum_PYR-GCK ----------MAETPDQLNWQSVPDPTPGPGEVLIRVHAAGVNRADLLQA
MAV_0308|M.avium_104 ---MRAVVCRSYGTPEDLVLDEVPDPVPGPGQLLVRVRAAAVNFPDVLFI
MMAR_1738|M.marinum_M --MRALRAHRR-GGPETLAVERAPVPVPAAGEVVVAVRAAGITFDELTWD
MSMEG_4442|M.smegmatis_MC2_155 --MKAVTVSDRDAGVSGLSLTELPYPVVSENDVVVRVHAAGFTRGELDWP
MAB_4371|M.abscessus_ATCC_1997 MLAAVAESQSAADPLAGLVLKDLPIPTPPSGWSVVRVVSSSLNMHDLWTL
TH_2475|M.thermoresistible__bu -------------------------------------------------M
Mvan_5758|M.vanbaalenii_PYR-1 -----MRAAVLTAYNSPLLVDELPDPEPGPGEVLVRVMASGVNPLDIKIR
Mb3806|M.bovis_AF2122/97 AGKYPPPPG-----------VSDIIGLEVSGIVAAVGPGVTEWSAGQEVC
Rv3777|M.tuberculosis_H37Rv AGKYPPPPG-----------VSDIIGLEVSGIVAAVGPGVTEWSAGQEVC
MUL_0096|M.ulcerans_Agy99 AGKYPPPPG-----------ASEIIGMEVSGTITDIGDGVTEWSAGQEVC
MLBr_00118|M.leprae_Br4923 AGKYPHPPG-----------ASAIIGMEVAGVVAAVSSGVTEWSVGQEVC
Mflv_1189|M.gilvum_PYR-GCK AGKYPPPPG-----------ASEIIGLEASGTIAAVGDGVTEWSEGQRVC
MAV_0308|M.avium_104 AGKYQVKIP-----------PPFIPGNEIAGEVIAAGEGARFLP-GQRVA
MMAR_1738|M.marinum_M QTWT-RDGVSR---------TPVIPSHEVSGVIHEIGSGTEDFHCGDEVY
MSMEG_4442|M.smegmatis_MC2_155 DTWTERSGRDR---------TPSVPGHELSGVVVELGYGTTRFTIGQRVF
MAB_4371|M.abscessus_ATCC_1997 RGVGHPADRLPIVLGCDAAGFDQDGNEVIVYPVIANPDAGMGDETLDPDR
TH_2475|M.thermoresistible__bu DGAGMRCD---------------TGEEVVIYPCLNWGDNRAGPG---SHF
Mvan_5758|M.vanbaalenii_PYR-1 RGEAPHAQLP----------PPAVLGIDMAGVVEAVGPRVDRFTVGDEVF
Mb3806|M.bovis_AF2122/97 ALLAGG-----GYAEYVAVPADQVLPIPPSVNLVDSAALPEVACTVWSNL
Rv3777|M.tuberculosis_H37Rv ALLAGG-----GYAEYVAVPADQVLPIPPSVNLVDSAALPEVACTVWSNL
MUL_0096|M.ulcerans_Agy99 ALLAGG-----GYAEYVAVPAGQVLPMPPGVSLIDAAALPEVACTVWSNL
MLBr_00118|M.leprae_Br4923 ALLAGG-----GYAEYVAVPASQVMPIPKGVNVVDSAGIPEVACTVWSNL
Mflv_1189|M.gilvum_PYR-GCK ALLAGG-----GYAEYVAVPAGQVLPVPDGVPLDHAAGLPEVACTVWSNL
MAV_0308|M.avium_104 GTTFG------AFAEQALLDADQAEPIPDDADFASAAAFGVTYRTAYHAL
MMAR_1738|M.marinum_M GLIGFDR--DGAAADFVAVPAAHLAAKPATISHTVAAALPLAGLTALQAL
MSMEG_4442|M.smegmatis_MC2_155 GLADWAR--NGSLAEYAAVETRHLAPLPYDVDHTLAAALPISGLSAWQGL
MAB_4371|M.abscessus_ATCC_1997 ALLSERH--DGAFAEYLTVPTRNLVPKPAWLSFDEAACLPVAWTTAYRML
TH_2475|M.thermoresistible__bu AIVGDAT--DGTYAELVAVPESVLYPKPPKLSWEEAAALPCAALTAYRAL
Mvan_5758|M.vanbaalenii_PYR-1 GMTGGVGGLQGSLAELAAVDARLIAHKPRTLSMAQAAALPLGFITSWEGL
. *: : * :* : : *
Mb3806|M.bovis_AF2122/97 VMTAHLRPGQLVLIHGGASGIGSHAIQVARALAARVAITAGSPEKLELCR
Rv3777|M.tuberculosis_H37Rv VMTAHLRPGQLVLIHGGASGIGSHAIQVVRALAARVAITAGSPEKLELCR
MUL_0096|M.ulcerans_Agy99 VMTAHLGPGQLVLIHGGACGIGSHAIQVCTALGARVAVTAGSSEKLQLSR
MLBr_00118|M.leprae_Br4923 VMAAHLSAGQLLLLHGGTSGIGSHGIQVARALGAKVAVTAGSEEKLEFCR
Mflv_1189|M.gilvum_PYR-GCK VMTARLRAPELLLIHGGASGIGTHAIQVARALNCRVAVTAGSRNKLDLCA
MAV_0308|M.avium_104 RSTAGVTAGDWVVVLGAAGGVGLAAVDLAVAMQARVLAAASSPEKLELCR
MMAR_1738|M.marinum_M VDHAAVRPGEAVLVHGGAGGVGALVVQLAAILGANVTATVRSDA-GELVS
MSMEG_4442|M.smegmatis_MC2_155 FEHAQLVAGQTVLIHGAAGGVGSIAVQLAREVGARVIGTGRAAD-RDRAL
MAB_4371|M.abscessus_ATCC_1997 FTHAKITAGARVLVQGVGGGVASAAIRLASAAGAVVYATSRSEAKRQTAI
TH_2475|M.thermoresistible__bu FTRARVMAGETVLVLGAGGDVSTFAVMFAAAADAEVYVTSSSPSKIRAVQ
Mvan_5758|M.vanbaalenii_PYR-1 VDRAGVGTGQQVLIHGGAGGVGFLAVQLALARGAQVYATGSTSSQAVIRA
* : . ::: * .:. : . . * : :
Mb3806|M.bovis_AF2122/97 DLGAQITINYRDEDFVARLK-QETDGSGADIILDIMGASYLDRNIDALA-
Rv3777|M.tuberculosis_H37Rv DLGAQITINYRDEDFVARLK-QETDGSGADIILDIMGASYLDRNIDALA-
MUL_0096|M.ulcerans_Agy99 DLGAQITINYRDEDFVARLK-QETDGSGADVILDIMGAAYLDRNVDALA-
MLBr_00118|M.leprae_Br4923 ALGAQITINYRDEDFVARLQ-QQN--GGADVILDIMGAAYLDRNIDALA-
Mflv_1189|M.gilvum_PYR-GCK ELGAEITIDYHHEDFVEVLRGADSDHPGADVILDIMGASYLDRNIDALA-
MAV_0308|M.avium_104 RRGAEATVDYDREDLKTRIR--DLTGDRARVVLDPVGGPYSEPALRGLA-
MMAR_1738|M.marinum_M RLGAQRVIDTRTEAFERTAT-------DFDVVIDTVGGDTLDRSFAVLR-
MSMEG_4442|M.smegmatis_MC2_155 ELGTHTFLDLDDDKLEDAG--------EVDVVFDVIGGEIMERSIALVR-
MAB_4371|M.abscessus_ATCC_1997 SWGAR-DAYATGERLPERVD---VVIETVGEATWSHS-------LKSLR-
TH_2475|M.thermoresistible__bu KIGAKGGVLHTDPDWPQQVR---ELTSGGADVIISGSGSMVTGALDCVK-
Mvan_5758|M.vanbaalenii_PYR-1 AGAVPIDYTATTVDEYVAAH---TGGEGFDVVADNVGGATLDASFTAVKR
.. . . :
Mb3806|M.bovis_AF2122/97 -TDGQLIVIGMQGGVKAELNLGKLLTKRARVIGTTLRARPVSGPHGKAAI
Rv3777|M.tuberculosis_H37Rv -TDGQLIVIGMQGGVKAELNLGKLLTKRARVIGTTLRARPVSGPHGKAAI
MUL_0096|M.ulcerans_Agy99 -VDGQLVIIGMQGGIKAELNLGKLLTKRARVIGTTLRARPLQGPNGKAVI
MLBr_00118|M.leprae_Br4923 -IDGQLIVIGLQGGVKGELNLGKVLSKRARIIGSTLRARPVNGPNSKSEI
Mflv_1189|M.gilvum_PYR-GCK -TGGRLVIIGMQGGTKAEINLGKLLAKRGSVMATALRSRPVTGRGSKSVI
MAV_0308|M.avium_104 -RGGTFVTLGYASGTIPAIPLNLVLLKDICVRGMEIRTFMTDRPDD----
MMAR_1738|M.marinum_M -PGGRLVTLSAPPPAGKADEHGVTAMFFIVTPNRDQ--------------
MSMEG_4442|M.smegmatis_MC2_155 -AGGTLVTLAEPPKTQPRDGR---ALYFLVEPDSAR--------------
MAB_4371|M.abscessus_ATCC_1997 -PGGCIVIAGATTGMNPPADLGRVFYLQQRILGSTGCTR-----------
TH_2475|M.thermoresistible__bu -VGGRIAVFGPCGGRMAMINVPALFLGQVSILGSNLGSP-----------
Mvan_5758|M.vanbaalenii_PYR-1 YTGHVVSALGWGTHSLAPLSFRGAAYSGVFTLMPLLTGRGRDHHG-----
. . .
Mb3806|M.bovis_AF2122/97 AQAVAASVWPMIAANRVRPVIG-TRLPIQQAAQAHELMLSG-KTFGKILL
Rv3777|M.tuberculosis_H37Rv AQAVAASVWPMIAANRVRPVIG-TRLPIQQAAQAHELMLSG-KTFGKILL
MUL_0096|M.ulcerans_Agy99 AQAVTASVWPMIASNRVRPIIG-SRLPIGQAAQAHQLLLSG-QSYGKILL
MLBr_00118|M.leprae_Br4923 VAAVTASIWPMIADGSVRPIIG-ARMAVQQAADAHQLLLSG-KVSGKIVL
Mflv_1189|M.gilvum_PYR-GCK VSEVIENVWPLVADGQVRPVIG-AEFPISEAQAAHELLASG-DVSGKVIL
MAV_0308|M.avium_104 AVRDLTELSQMFAAGTVRPYIG-ARFPLARTAAALRHVADR-KVLGKVVI
MMAR_1738|M.marinum_M ----LNRLGELVGSGRLHVEIA-QSFPLANGREAFESGRGAARRAGKTVI
MSMEG_4442|M.smegmatis_MC2_155 ----LADLAARVRTGRLKPVVG-RVVPLADAPSAFNQKK---RTTGKTIV
MAB_4371|M.abscessus_ATCC_1997 --SELIAMLRMLDATGIRPVID-RTMPLAEIHKAFQLMIDG-GLTGKLVI
TH_2475|M.thermoresistible__bu --DDFGEMLVFVRRNDIRPVID-RVYPLSEISRAHSYFESQ-VRVGKVVV
Mvan_5758|M.vanbaalenii_PYR-1 --EIVAEAAALADSGRLAPRLHPTTFPLDAVNDAHTAVESG-SATGKVVV
: : .: * ** ::
Mb3806|M.bovis_AF2122/97 TV-------------
Rv3777|M.tuberculosis_H37Rv TV-------------
MUL_0096|M.ulcerans_Agy99 TVDG-----------
MLBr_00118|M.leprae_Br4923 TVAGSGTETLLSRHH
Mflv_1189|M.gilvum_PYR-GCK RVDV-----------
MAV_0308|M.avium_104 DVA------------
MMAR_1738|M.marinum_M TVGQ-----------
MSMEG_4442|M.smegmatis_MC2_155 RVTED----------
MAB_4371|M.abscessus_ATCC_1997 HPDPN----------
TH_2475|M.thermoresistible__bu TTPA-----------
Mvan_5758|M.vanbaalenii_PYR-1 EPNV-----------