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M. abscessus ATCC 19977 MAB_4269 (-)

annotation: monooxygenase
coordinates: 4340627 - 4341781
length: 384

VGLEDVEALHDLVGGVELSGNKLVRSFYSRWFAIDPTVGDLFPADMSAQREHFRQALQFVLWEMASYRTE
GLVNFLAQLGRDHRKFGATDSQYDTMRQALLDTTREVLQPIWDQRMEATATEVYTVMIEVMRSAAASDIG
QPWWDGKVIEFHRTSRDLALIRLKLNAPMPYHCGQYVHVQVPQSPRNWRYLSLAIPPDPEGYIEFHVRAV
PGGLVSGDIVNKTKVGDTWRISPPLGALSVNRDGGDILMVAGSTGIAPLRCLIMELSQWAENPRVHLFYG
ARYPQELYDLWTLWHIASTNPWLSVTPVTEYPRNPDWATEYHDPTPPRGLHVRQTGLLSEVVTAYGGWGD
RQILIGGSASMIQATKEALVSRGADASRIQHDPL
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. abscessus ATCC 19977MAB_4269--100% (384)monooxygenase
M. abscessus ATCC 19977MAB_3133c-7e-0923.67% (283) putative flavohemoprotein
M. abscessus ATCC 19977MAB_1588c-3e-0525.78% (225) putative oxidoreductase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0392-1e-12958.76% (388) hypothetical protein Mb0392
M. gilvum PYR-GCKMflv_0255-1e-12257.02% (363) oxidoreductase FAD-binding subunit
M. tuberculosis H37RvRv0385-1e-12958.76% (388) hypothetical protein Rv0385
M. leprae Br4923-----
M. marinum MMMAR_0644-1e-12757.14% (392) monooxygenase
M. avium 104MAV_4795-1e-12859.59% (391) oxidoreductase FAD-binding subunit
M. smegmatis MC2 155MSMEG_0719-1e-12358.56% (362) flavohemoprotein
M. thermoresistible (build 8)TH_2358-1e-12958.81% (386) PROBABLE MONOOXYGENASE
M. ulcerans Agy99MUL_0128-1e-12656.89% (392) monooxygenase
M. vanbaalenii PYR-1Mvan_0639-1e-12656.48% (386) oxidoreductase FAD-binding subunit

CLUSTAL 2.0.9 multiple sequence alignment


Mb0392|M.bovis_AF2122/97            MGLEDRDALRVLQNAFKL-DDP-------ELVRRFYAHWFALDASVRDLF
Rv0385|M.tuberculosis_H37Rv         MGLEDRDALRVLQNAFKL-DDP-------ELVRRFYAHWFALDASVRDLF
MAV_4795|M.avium_104                MSLEDADALRVLRDAFAP-CDAGRPGDSGDLVHRFYTHWFALDPSVRDLF
MMAR_0644|M.marinum_M               MGLEDRDALRVLRDAFAPQPDLDHKTQSSELVRSFYTNWFSLDSSVRDLF
MUL_0128|M.ulcerans_Agy99           MGLEDRDALRVLRDAFAPQPDLDHKTQSSELVRSFYTNWFSLDSSVRDLF
Mflv_0255|M.gilvum_PYR-GCK          --------MRILREAFEPGPGSE------RLVGEFYTRWFAADLTARDLF
Mvan_0639|M.vanbaalenii_PYR-1       MGLEDRESMRILRDALDLDLGSE------ALIGDFHTRWFAADLSARDLF
MSMEG_0719|M.smegmatis_MC2_155      ----------MLRAAVDPANDSD------PLIRDFYTNWFAADLSVRDLF
TH_2358|M.thermoresistible__bu      VGLDDGESLRTLRAAVDPANGSD------ELIRTFYTRWFAADLSARDLF
MAB_4269|M.abscessus_ATCC_1997      MGLEDVEALHDLVGGVELSGNK--------LVRSFYSRWFAIDPTVGDLF
                                               *  ..    .         *:  *::.**: * :. ***

Mb0392|M.bovis_AF2122/97            PPDMGAQRAAFGQALHWVYGELVAQRAEEPVAFLAQLGRDHRKYGVLPTQ
Rv0385|M.tuberculosis_H37Rv         PPDMGAQRAAFGQALHWVYGELVAQRAEEPVAFLAQLGRDHRKYGVLPTQ
MAV_4795|M.avium_104                PPEMGAQRVAFGHALHWVYGELVARRAQEPVAFLAQLGRDHRKYGVLPRH
MMAR_0644|M.marinum_M               PPEMSGQRAAFTRALHWVYSELVAQRAEEPIAFLAQLGRDHRKYGVQPTQ
MUL_0128|M.ulcerans_Agy99           PPEMSGQRAAFTRALHWVYSELVAQCAEEPIAFLAQLGRDHRKYGVQPTQ
Mflv_0255|M.gilvum_PYR-GCK          PPDMAGQRQVFAHAMRWLCDELIAQRAEEPVAFLAQLGRDHRKYGVTPEH
Mvan_0639|M.vanbaalenii_PYR-1       PPDLEKQRQVFAQALCWLCDELIAQRAEEPVAFLAQLGRDHRKYGVTQSH
MSMEG_0719|M.smegmatis_MC2_155      PPEMAEQRRVFAHALTWLFGELIAQRAEDPITFLAQLGRDHRKYGVTQQH
TH_2358|M.thermoresistible__bu      PPDMAAQRAAFAEVLTWLLGELIAQRAHEPVAFLAQLGRDHRKYGVTQAH
MAB_4269|M.abscessus_ATCC_1997      PADMSAQREHFRQALQFVLWEMASYRTEGLVNFLAQLGRDHRKFGATDSQ
                                    *.::  **  * ..: ::  *: :  :.  : ***********:*.   :

Mb0392|M.bovis_AF2122/97            YDTLRRALYTTLRDYLGHPSRGAWTDAVDEAAGQSLNLIIGVMSGAADAD
Rv0385|M.tuberculosis_H37Rv         YDTLRRALYTTLRDYLGHPSRGAWTDAVDEAAGQSLNLIIGVMSGAADAD
MAV_4795|M.avium_104                YQTLGRALLATLRSHL----DAAWTDAVEDAARTSLNLITGVMSGAADAD
MMAR_0644|M.marinum_M               YETLRRALQTTLRSHLG----SSWTDSVARAAEQSLNLIVGVMSGAADSE
MUL_0128|M.ulcerans_Agy99           YETLRRALQTTLRSHLG----SSWTDSVARAAEQSLNLIVGVMSGAADSE
Mflv_0255|M.gilvum_PYR-GCK          YAGLQDALLAAVRTTLT----DRWDARLEEAATDVVTLAVGVMSGAGEAE
Mvan_0639|M.vanbaalenii_PYR-1       YATLQDALLTTLRKALV----EQWDRRLAEAVDDVVQLVVGVMSGAADAE
MSMEG_0719|M.smegmatis_MC2_155      YDSMQSALYGALKARLA----DRWTDRLAAATRDAVALFIGVMRGAADAE
TH_2358|M.thermoresistible__bu      YDTMHEALYTTLRDHLN----DRWTDRLAEAAHDAVTLFTGVMRGAAEAE
MAB_4269|M.abscessus_ATCC_1997      YDTMRQALLDTTREVLQ----PIWDQRMEATATEVYTVMIEVMRSAAASD
                                    *  :  **  : :  *       *   :  :.     :   ** .*. ::

Mb0392|M.bovis_AF2122/97            DAPAWWDGTVVEHIRVSRDLAVARLQLDRPLHYYPGQYVNVHVPQCPRRW
Rv0385|M.tuberculosis_H37Rv         DAPAWWDGTVVEHIRVSRDLAVARLQLDRPLHYYPGQYVNVHVPQCPRRW
MAV_4795|M.avium_104                EGPAWWDGTVIGHLRVSRDLAVVRLRLDQPMPYHPGQYVNVQVPQCPRRW
MMAR_0644|M.marinum_M               DGPAWWDATVIEHIPASRDLAVIRLQLDHPMPYHPGQYVNVQVPQCPRRW
MUL_0128|M.ulcerans_Agy99           DGPAWSDATVIEHIPASRDLAVIRLQLDHPMPYHPGQYVNVQVPQCPRRW
Mflv_0255|M.gilvum_PYR-GCK          TAPPFCDGTVLEHLRPTRDVSVIRLKMDHHIDYHAGQYVSVQVPQWPRRW
Mvan_0639|M.vanbaalenii_PYR-1       TSPPFCDGTVLEHLRPARDISVIRLKMDHALAYHPGQYVPVQVPQWPRRW
MSMEG_0719|M.smegmatis_MC2_155      ESPAYCDGTVVETHRLTRDVSVIRLQLDEPLFYHSGQYVTVQVPQWPRRW
TH_2358|M.thermoresistible__bu      QGPPYCDGTVVEHLRVGRDVSVVRLQLDRPLFYHPGQYVTVQVPQWPRRW
MAB_4269|M.abscessus_ATCC_1997      IGQPWWDGKVIEFHRTSRDLALIRLKLNAPMPYHCGQYVHVQVPQSPRNW
                                     . .: *..*:      **::: **:::  : *: **** *:*** **.*

Mb0392|M.bovis_AF2122/97            RYLSPAIPADPNGRIEFHVRVVPGGLVSNAIVGETRPGDRWRLSGPHGAF
Rv0385|M.tuberculosis_H37Rv         RYLSPAIPADPNGRIEFHVRVVPGGLVSNAIVGETRPGDRWRLSGPHGAF
MAV_4795|M.avium_104                RYLSPAIPADPGCGIEFHVRLVPGGLVSTAIVNETRPGDRWRLSSPHGGL
MMAR_0644|M.marinum_M               RYLSPAIPADLEGRIEFHVRVVPGGLVSTAMVNETRTGDRWRLASPHGGL
MUL_0128|M.ulcerans_Agy99           RYLSPAIPADLEGRIEFHVRVVPGGLVSTAMVNETRTGDRWRLASPHGGL
Mflv_0255|M.gilvum_PYR-GCK          RFLSPAIPADPQGYVEFHVRSVAGGMVSTTILGETRPGDRWRLAAPHGAM
Mvan_0639|M.vanbaalenii_PYR-1       RYLSPAIPADPQGYLEFHIRSVAGGMVSTAIVGEARPGDRWRVSNPHGAM
MSMEG_0719|M.smegmatis_MC2_155      RYLSPAIPSDRSGAIEFHVRSVTGGMVSTAIVNETRHGDRWRVSSPHGAL
TH_2358|M.thermoresistible__bu      RYLSPAIPADRSGAIEFHIRSVIGGMVSTAIVNETRPGDRWRISHPHGSL
MAB_4269|M.abscessus_ATCC_1997      RYLSLAIPPDPEGYIEFHVRAVPGGLVSGDIVNKTKVGDTWRISPPLGAL
                                    *:** ***.*    :***:* * **:**  ::.::: ** **:: * *.:

Mb0392|M.bovis_AF2122/97            RVDRDGGDVLMVAGSTGLAPLRALIIDLSRFAVNPRVHLFFGARYACELY
Rv0385|M.tuberculosis_H37Rv         RVDRDGGDVLMVAGSTGLAPLRALIIDLSRFAVNPRVHLFFGARYACELY
MAV_4795|M.avium_104                RVDRDGGDVLMVAGSTGLAPLRALIMDLSRFAVNPRVHLFFGARYRCELY
MMAR_0644|M.marinum_M               HVDRTGGDVLMVAGSTGLAPLRALILDMGRFVENPRVHLFFGARYFCELY
MUL_0128|M.ulcerans_Agy99           HVDRTGGDVLMVAGSTGLAPLRALILDMGRFVENPRVHLFFGARYFCELY
Mflv_0255|M.gilvum_PYR-GCK          HVDREAGDVLMVAGSTGLAPLRALIMDMCRFAANPRVHLFFGAKYPCELY
Mvan_0639|M.vanbaalenii_PYR-1       EIDRDGGDVLMVAGSTGLAPLRTLIMDLARFSQNPRVHLFFGAKYPCELY
MSMEG_0719|M.smegmatis_MC2_155      EVNRSGEDVLMVAGSTGLAPLRALIMDMTLHAENPRVHLFFGGRFPCDLY
TH_2358|M.thermoresistible__bu      HIDRDGGDVLMVAGSTGLAPLRTLIMDLTRFGVNPRVHLFFGARYPCDLY
MAB_4269|M.abscessus_ATCC_1997      SVNRDGGDILMVAGSTGIAPLRCLIMELSQWAENPRVHLFYGARYPQELY
                                     ::* . *:********:**** **:::     *******:*.::  :**

Mb0392|M.bovis_AF2122/97            DLPTLWQIAAHNPWLSVSPVSEYNGDPAWAADYPDVSAPRGLHVRQTGRL
Rv0385|M.tuberculosis_H37Rv         DLPTLWQIAAHNPWLSVSPVSEYNGDPAWAADYPDVSAPRGLHVRQTGRL
MAV_4795|M.avium_104                DLPTLWQIASHNPWLSVSPVSEYRADPPWAADYPDVTPPRGLHVHQTGRL
MMAR_0644|M.marinum_M               DLRTLWQVAAHNPWLSVSPVAEYKLDPSWATDYPDVSPPRGLHVRQTGRL
MUL_0128|M.ulcerans_Agy99           DLRTLWHVAAHNPWLSVSPVAEYKLDPSWATDYPDVSPPRGLHVRQTGRL
Mflv_0255|M.gilvum_PYR-GCK          DLPTLWEVASMNPWLSVTPVSEFDFDPPWAAEYPDNRPPRGLHVRQTGRL
Mvan_0639|M.vanbaalenii_PYR-1       DLRTLWEIASTNPWLSVTPVSELNFDPPWAADYPDVTPPRGLHVRQLGLL
MSMEG_0719|M.smegmatis_MC2_155      DLKTLWTIASTNPWLSVTPVSEYSTDPPWARDYPDPTPPRGLHVRQTGTL
TH_2358|M.thermoresistible__bu      DLKTLWQIASTNPWLSVTPVSEYSVDPPWASEYPDVQPPRGLHVRQTGLL
MAB_4269|M.abscessus_ATCC_1997      DLWTLWHIASTNPWLSVTPVTEYPRNPDWATEYHDPTPPRGLHVRQTGLL
                                    ** *** :*: ******:**:*   :* ** :* *  .******:* * *

Mb0392|M.bovis_AF2122/97            PDVVSRYGGWGDRQILICGGPAMVRATKAALIAKGAPPERIQHDPLSR-
Rv0385|M.tuberculosis_H37Rv         PDVVSRYGGWGDRQILICGGPAMVRATKAALIAKGAPPERIQHDPLSR-
MAV_4795|M.avium_104                PEVVTKYGGWGDRQILICGGPRMVAATKAALIAKGAAAQRIQHDPLSR-
MMAR_0644|M.marinum_M               AEVVTNYGNWGDRQILICGGPAMVRTTKAALIAKGAPRERIQHDPLP--
MUL_0128|M.ulcerans_Agy99           AEVVTNYGNWGDRQILICGGPAMVRTTKAALIAKGAPRERIQHDPLP--
Mflv_0255|M.gilvum_PYR-GCK          DEVVTRYGSWGDRQILVCGRPEMVAATRSALIAKGAPAERIQHDPLGN-
Mvan_0639|M.vanbaalenii_PYR-1       PEVVTRYGNWSDRQILLSGRPAMVQATKAALITKGAPAERIQHDPLAN-
MSMEG_0719|M.smegmatis_MC2_155      ADVVTRYGNWGDRQILICGGPQMVEATKAALIAKGAPPERIQHDPLTAR
TH_2358|M.thermoresistible__bu      PEVVTRYGAWSDRQILICGSPEMVQATKAALIAKGAPPERIQHDPLSY-
MAB_4269|M.abscessus_ATCC_1997      SEVVTAYGGWGDRQILIGGSASMIQATKEALVSRGADASRIQHDPL---
                                     :**: ** *.*****: * . *: :*: **:::**  .*******