For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. marinum M MMAR_0644 (-)

annotation: monooxygenase
coordinates: 776672 - 777853
length: 393

GLEDRDALRVLRDAFAPQPDLDHKTQSSELVRSFYTNWFSLDSSVRDLFPPEMSGQRAAFTRALHWVYSE
LVAQRAEEPIAFLAQLGRDHRKYGVQPTQYETLRRALQTTLRSHLGSSWTDSVARAAEQSLNLIVGVMSG
AADSEDGPAWWDATVIEHIPASRDLAVIRLQLDHPMPYHPGQYVNVQVPQCPRRWRYLSPAIPADLEGRI
EFHVRVVPGGLVSTAMVNETRTGDRWRLASPHGGLHVDRTGGDVLMVAGSTGLAPLRALILDMGRFVENP
RVHLFFGARYFCELYDLRTLWQVAAHNPWLSVSPVAEYKLDPSWATDYPDVSPPRGLHVRQTGRLAEVVT
NYGNWGDRQILICGGPAMVRTTKAALIAKGAPRERIQHDPLP*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_0644--100% (393)monooxygenase
M. marinum MMMAR_2865-3e-1428.17% (213) oxygenase
M. marinum MMMAR_0128-2e-1226.11% (226) oxidoreductase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0392-0.077.78% (396) hypothetical protein Mb0392
M. gilvum PYR-GCKMflv_0255-1e-14864.58% (384) oxidoreductase FAD-binding subunit
M. tuberculosis H37RvRv0385-0.077.78% (396) hypothetical protein Rv0385
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_4269-1e-12757.14% (392) monooxygenase
M. avium 104MAV_4795-0.077.55% (392) oxidoreductase FAD-binding subunit
M. smegmatis MC2 155MSMEG_0719-1e-15167.02% (382) flavohemoprotein
M. thermoresistible (build 8)TH_2358-1e-16067.60% (392) PROBABLE MONOOXYGENASE
M. ulcerans Agy99MUL_0128-0.099.24% (393) monooxygenase
M. vanbaalenii PYR-1Mvan_0639-1e-15365.05% (392) oxidoreductase FAD-binding subunit

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_0255|M.gilvum_PYR-GCK          --------MRILREAFEPGPGSE------RLVGEFYTRWFAADLTARDLF
Mvan_0639|M.vanbaalenii_PYR-1       MGLEDRESMRILRDALDLDLGSE------ALIGDFHTRWFAADLSARDLF
MSMEG_0719|M.smegmatis_MC2_155      ----------MLRAAVDPANDSD------PLIRDFYTNWFAADLSVRDLF
TH_2358|M.thermoresistible__bu      VGLDDGESLRTLRAAVDPANGSD------ELIRTFYTRWFAADLSARDLF
MMAR_0644|M.marinum_M               MGLEDRDALRVLRDAFAPQPDLDHKTQSSELVRSFYTNWFSLDSSVRDLF
MUL_0128|M.ulcerans_Agy99           MGLEDRDALRVLRDAFAPQPDLDHKTQSSELVRSFYTNWFSLDSSVRDLF
Mb0392|M.bovis_AF2122/97            MGLEDRDALRVLQNAFKL-DDP-------ELVRRFYAHWFALDASVRDLF
Rv0385|M.tuberculosis_H37Rv         MGLEDRDALRVLQNAFKL-DDP-------ELVRRFYAHWFALDASVRDLF
MAV_4795|M.avium_104                MSLEDADALRVLRDAFAP-CDAGRPGDSGDLVHRFYTHWFALDPSVRDLF
MAB_4269|M.abscessus_ATCC_1997      MGLEDVEALHDLVGGVELSGNK--------LVRSFYSRWFAIDPTVGDLF
                                               *  ..    .         *:  *::.**: * :. ***

Mflv_0255|M.gilvum_PYR-GCK          PPDMAGQRQVFAHAMRWLCDELIAQRAEEPVAFLAQLGRDHRKYGVTPEH
Mvan_0639|M.vanbaalenii_PYR-1       PPDLEKQRQVFAQALCWLCDELIAQRAEEPVAFLAQLGRDHRKYGVTQSH
MSMEG_0719|M.smegmatis_MC2_155      PPEMAEQRRVFAHALTWLFGELIAQRAEDPITFLAQLGRDHRKYGVTQQH
TH_2358|M.thermoresistible__bu      PPDMAAQRAAFAEVLTWLLGELIAQRAHEPVAFLAQLGRDHRKYGVTQAH
MMAR_0644|M.marinum_M               PPEMSGQRAAFTRALHWVYSELVAQRAEEPIAFLAQLGRDHRKYGVQPTQ
MUL_0128|M.ulcerans_Agy99           PPEMSGQRAAFTRALHWVYSELVAQCAEEPIAFLAQLGRDHRKYGVQPTQ
Mb0392|M.bovis_AF2122/97            PPDMGAQRAAFGQALHWVYGELVAQRAEEPVAFLAQLGRDHRKYGVLPTQ
Rv0385|M.tuberculosis_H37Rv         PPDMGAQRAAFGQALHWVYGELVAQRAEEPVAFLAQLGRDHRKYGVLPTQ
MAV_4795|M.avium_104                PPEMGAQRVAFGHALHWVYGELVARRAQEPVAFLAQLGRDHRKYGVLPRH
MAB_4269|M.abscessus_ATCC_1997      PADMSAQREHFRQALQFVLWEMASYRTEGLVNFLAQLGRDHRKFGATDSQ
                                    *.::  **  * ..: ::  *: :  :.  : ***********:*.   :

Mflv_0255|M.gilvum_PYR-GCK          YAGLQDALLAAVRTTLT----DRWDARLEEAATDVVTLAVGVMSGAGEAE
Mvan_0639|M.vanbaalenii_PYR-1       YATLQDALLTTLRKALV----EQWDRRLAEAVDDVVQLVVGVMSGAADAE
MSMEG_0719|M.smegmatis_MC2_155      YDSMQSALYGALKARLA----DRWTDRLAAATRDAVALFIGVMRGAADAE
TH_2358|M.thermoresistible__bu      YDTMHEALYTTLRDHLN----DRWTDRLAEAAHDAVTLFTGVMRGAAEAE
MMAR_0644|M.marinum_M               YETLRRALQTTLRSHLG----SSWTDSVARAAEQSLNLIVGVMSGAADSE
MUL_0128|M.ulcerans_Agy99           YETLRRALQTTLRSHLG----SSWTDSVARAAEQSLNLIVGVMSGAADSE
Mb0392|M.bovis_AF2122/97            YDTLRRALYTTLRDYLGHPSRGAWTDAVDEAAGQSLNLIIGVMSGAADAD
Rv0385|M.tuberculosis_H37Rv         YDTLRRALYTTLRDYLGHPSRGAWTDAVDEAAGQSLNLIIGVMSGAADAD
MAV_4795|M.avium_104                YQTLGRALLATLRSHL----DAAWTDAVEDAARTSLNLITGVMSGAADAD
MAB_4269|M.abscessus_ATCC_1997      YDTMRQALLDTTREVLQ----PIWDQRMEATATEVYTVMIEVMRSAAASD
                                    *  :  **  : :  *       *   :  :.     :   ** .*. ::

Mflv_0255|M.gilvum_PYR-GCK          TAPPFCDGTVLEHLRPTRDVSVIRLKMDHHIDYHAGQYVSVQVPQWPRRW
Mvan_0639|M.vanbaalenii_PYR-1       TSPPFCDGTVLEHLRPARDISVIRLKMDHALAYHPGQYVPVQVPQWPRRW
MSMEG_0719|M.smegmatis_MC2_155      ESPAYCDGTVVETHRLTRDVSVIRLQLDEPLFYHSGQYVTVQVPQWPRRW
TH_2358|M.thermoresistible__bu      QGPPYCDGTVVEHLRVGRDVSVVRLQLDRPLFYHPGQYVTVQVPQWPRRW
MMAR_0644|M.marinum_M               DGPAWWDATVIEHIPASRDLAVIRLQLDHPMPYHPGQYVNVQVPQCPRRW
MUL_0128|M.ulcerans_Agy99           DGPAWSDATVIEHIPASRDLAVIRLQLDHPMPYHPGQYVNVQVPQCPRRW
Mb0392|M.bovis_AF2122/97            DAPAWWDGTVVEHIRVSRDLAVARLQLDRPLHYYPGQYVNVHVPQCPRRW
Rv0385|M.tuberculosis_H37Rv         DAPAWWDGTVVEHIRVSRDLAVARLQLDRPLHYYPGQYVNVHVPQCPRRW
MAV_4795|M.avium_104                EGPAWWDGTVIGHLRVSRDLAVVRLRLDQPMPYHPGQYVNVQVPQCPRRW
MAB_4269|M.abscessus_ATCC_1997      IGQPWWDGKVIEFHRTSRDLALIRLKLNAPMPYHCGQYVHVQVPQSPRNW
                                     . .: *..*:      **::: **:::  : *: **** *:*** **.*

Mflv_0255|M.gilvum_PYR-GCK          RFLSPAIPADPQGYVEFHVRSVAGGMVSTTILGETRPGDRWRLAAPHGAM
Mvan_0639|M.vanbaalenii_PYR-1       RYLSPAIPADPQGYLEFHIRSVAGGMVSTAIVGEARPGDRWRVSNPHGAM
MSMEG_0719|M.smegmatis_MC2_155      RYLSPAIPSDRSGAIEFHVRSVTGGMVSTAIVNETRHGDRWRVSSPHGAL
TH_2358|M.thermoresistible__bu      RYLSPAIPADRSGAIEFHIRSVIGGMVSTAIVNETRPGDRWRISHPHGSL
MMAR_0644|M.marinum_M               RYLSPAIPADLEGRIEFHVRVVPGGLVSTAMVNETRTGDRWRLASPHGGL
MUL_0128|M.ulcerans_Agy99           RYLSPAIPADLEGRIEFHVRVVPGGLVSTAMVNETRTGDRWRLASPHGGL
Mb0392|M.bovis_AF2122/97            RYLSPAIPADPNGRIEFHVRVVPGGLVSNAIVGETRPGDRWRLSGPHGAF
Rv0385|M.tuberculosis_H37Rv         RYLSPAIPADPNGRIEFHVRVVPGGLVSNAIVGETRPGDRWRLSGPHGAF
MAV_4795|M.avium_104                RYLSPAIPADPGCGIEFHVRLVPGGLVSTAIVNETRPGDRWRLSSPHGGL
MAB_4269|M.abscessus_ATCC_1997      RYLSLAIPPDPEGYIEFHVRAVPGGLVSGDIVNKTKVGDTWRISPPLGAL
                                    *:** ***.*    :***:* * **:**  ::.::: ** **:: * *.:

Mflv_0255|M.gilvum_PYR-GCK          HVDREAGDVLMVAGSTGLAPLRALIMDMCRFAANPRVHLFFGAKYPCELY
Mvan_0639|M.vanbaalenii_PYR-1       EIDRDGGDVLMVAGSTGLAPLRTLIMDLARFSQNPRVHLFFGAKYPCELY
MSMEG_0719|M.smegmatis_MC2_155      EVNRSGEDVLMVAGSTGLAPLRALIMDMTLHAENPRVHLFFGGRFPCDLY
TH_2358|M.thermoresistible__bu      HIDRDGGDVLMVAGSTGLAPLRTLIMDLTRFGVNPRVHLFFGARYPCDLY
MMAR_0644|M.marinum_M               HVDRTGGDVLMVAGSTGLAPLRALILDMGRFVENPRVHLFFGARYFCELY
MUL_0128|M.ulcerans_Agy99           HVDRTGGDVLMVAGSTGLAPLRALILDMGRFVENPRVHLFFGARYFCELY
Mb0392|M.bovis_AF2122/97            RVDRDGGDVLMVAGSTGLAPLRALIIDLSRFAVNPRVHLFFGARYACELY
Rv0385|M.tuberculosis_H37Rv         RVDRDGGDVLMVAGSTGLAPLRALIIDLSRFAVNPRVHLFFGARYACELY
MAV_4795|M.avium_104                RVDRDGGDVLMVAGSTGLAPLRALIMDLSRFAVNPRVHLFFGARYRCELY
MAB_4269|M.abscessus_ATCC_1997      SVNRDGGDILMVAGSTGIAPLRCLIMELSQWAENPRVHLFYGARYPQELY
                                     ::* . *:********:**** **:::     *******:*.::  :**

Mflv_0255|M.gilvum_PYR-GCK          DLPTLWEVASMNPWLSVTPVSEFDFDPPWAAEYPDNRPPRGLHVRQTGRL
Mvan_0639|M.vanbaalenii_PYR-1       DLRTLWEIASTNPWLSVTPVSELNFDPPWAADYPDVTPPRGLHVRQLGLL
MSMEG_0719|M.smegmatis_MC2_155      DLKTLWTIASTNPWLSVTPVSEYSTDPPWARDYPDPTPPRGLHVRQTGTL
TH_2358|M.thermoresistible__bu      DLKTLWQIASTNPWLSVTPVSEYSVDPPWASEYPDVQPPRGLHVRQTGLL
MMAR_0644|M.marinum_M               DLRTLWQVAAHNPWLSVSPVAEYKLDPSWATDYPDVSPPRGLHVRQTGRL
MUL_0128|M.ulcerans_Agy99           DLRTLWHVAAHNPWLSVSPVAEYKLDPSWATDYPDVSPPRGLHVRQTGRL
Mb0392|M.bovis_AF2122/97            DLPTLWQIAAHNPWLSVSPVSEYNGDPAWAADYPDVSAPRGLHVRQTGRL
Rv0385|M.tuberculosis_H37Rv         DLPTLWQIAAHNPWLSVSPVSEYNGDPAWAADYPDVSAPRGLHVRQTGRL
MAV_4795|M.avium_104                DLPTLWQIASHNPWLSVSPVSEYRADPPWAADYPDVTPPRGLHVHQTGRL
MAB_4269|M.abscessus_ATCC_1997      DLWTLWHIASTNPWLSVTPVTEYPRNPDWATEYHDPTPPRGLHVRQTGLL
                                    ** *** :*: ******:**:*   :* ** :* *  .******:* * *

Mflv_0255|M.gilvum_PYR-GCK          DEVVTRYGSWGDRQILVCGRPEMVAATRSALIAKGAPAERIQHDPLGN-
Mvan_0639|M.vanbaalenii_PYR-1       PEVVTRYGNWSDRQILLSGRPAMVQATKAALITKGAPAERIQHDPLAN-
MSMEG_0719|M.smegmatis_MC2_155      ADVVTRYGNWGDRQILICGGPQMVEATKAALIAKGAPPERIQHDPLTAR
TH_2358|M.thermoresistible__bu      PEVVTRYGAWSDRQILICGSPEMVQATKAALIAKGAPPERIQHDPLSY-
MMAR_0644|M.marinum_M               AEVVTNYGNWGDRQILICGGPAMVRTTKAALIAKGAPRERIQHDPLP--
MUL_0128|M.ulcerans_Agy99           AEVVTNYGNWGDRQILICGGPAMVRTTKAALIAKGAPRERIQHDPLP--
Mb0392|M.bovis_AF2122/97            PDVVSRYGGWGDRQILICGGPAMVRATKAALIAKGAPPERIQHDPLSR-
Rv0385|M.tuberculosis_H37Rv         PDVVSRYGGWGDRQILICGGPAMVRATKAALIAKGAPPERIQHDPLSR-
MAV_4795|M.avium_104                PEVVTKYGGWGDRQILICGGPRMVAATKAALIAKGAAAQRIQHDPLSR-
MAB_4269|M.abscessus_ATCC_1997      SEVVTAYGGWGDRQILIGGSASMIQATKEALVSRGADASRIQHDPL---
                                     :**: ** *.*****: * . *: :*: **:::**  .*******