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M. thermoresistible (build 8) TH_2358 ()

annotation: PROBABLE MONOOXYGENASE
coordinates: 4630114 - 4631280
length: 389

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_2358-100% (389)PROBABLE MONOOXYGENASE
M. thermoresistible (build 8)TH_1871-8e-1124.24% (396) flavohemoprotein, putative
M. thermoresistible (build 8)TH_2872-4e-0729.81% (104) PUTATIVE 2Fe-2S iron-sulfur cluster binding domain protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0392-1e-16470.81% (394) hypothetical protein Mb0392
M. gilvum PYR-GCKMflv_0255-1e-16771.96% (378) oxidoreductase FAD-binding subunit
M. tuberculosis H37RvRv0385-1e-16470.81% (394) hypothetical protein Rv0385
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_4269-1e-12958.81% (386) monooxygenase
M. marinum MMMAR_0644-1e-16067.60% (392) monooxygenase
M. avium 104MAV_4795-1e-16570.41% (392) oxidoreductase FAD-binding subunit
M. smegmatis MC2 155MSMEG_0719-1e-18079.52% (376) flavohemoprotein
M. ulcerans Agy99MUL_0128-1e-15967.09% (392) monooxygenase
M. vanbaalenii PYR-1Mvan_0639-1e-17675.71% (387) oxidoreductase FAD-binding subunit

CLUSTAL 2.0.9 multiple sequence alignment


TH_2358|M.thermoresistible__bu      VGLDDGESLRTLRAAVDPANGSD------ELIRTFYTRWFAADLSARDLF
MSMEG_0719|M.smegmatis_MC2_155      ----------MLRAAVDPANDSD------PLIRDFYTNWFAADLSVRDLF
Mflv_0255|M.gilvum_PYR-GCK          --------MRILREAFEPGPGSE------RLVGEFYTRWFAADLTARDLF
Mvan_0639|M.vanbaalenii_PYR-1       MGLEDRESMRILRDALDLDLGSE------ALIGDFHTRWFAADLSARDLF
Mb0392|M.bovis_AF2122/97            MGLEDRDALRVLQNAFKL-DDP-------ELVRRFYAHWFALDASVRDLF
Rv0385|M.tuberculosis_H37Rv         MGLEDRDALRVLQNAFKL-DDP-------ELVRRFYAHWFALDASVRDLF
MAV_4795|M.avium_104                MSLEDADALRVLRDAFAP-CDAGRPGDSGDLVHRFYTHWFALDPSVRDLF
MMAR_0644|M.marinum_M               MGLEDRDALRVLRDAFAPQPDLDHKTQSSELVRSFYTNWFSLDSSVRDLF
MUL_0128|M.ulcerans_Agy99           MGLEDRDALRVLRDAFAPQPDLDHKTQSSELVRSFYTNWFSLDSSVRDLF
MAB_4269|M.abscessus_ATCC_1997      MGLEDVEALHDLVGGVELSGNK--------LVRSFYSRWFAIDPTVGDLF
                                               *  ..    .         *:  *::.**: * :. ***

TH_2358|M.thermoresistible__bu      PPDMAAQRAAFAEVLTWLLGELIAQRAHEPVAFLAQLGRDHRKYGVTQAH
MSMEG_0719|M.smegmatis_MC2_155      PPEMAEQRRVFAHALTWLFGELIAQRAEDPITFLAQLGRDHRKYGVTQQH
Mflv_0255|M.gilvum_PYR-GCK          PPDMAGQRQVFAHAMRWLCDELIAQRAEEPVAFLAQLGRDHRKYGVTPEH
Mvan_0639|M.vanbaalenii_PYR-1       PPDLEKQRQVFAQALCWLCDELIAQRAEEPVAFLAQLGRDHRKYGVTQSH
Mb0392|M.bovis_AF2122/97            PPDMGAQRAAFGQALHWVYGELVAQRAEEPVAFLAQLGRDHRKYGVLPTQ
Rv0385|M.tuberculosis_H37Rv         PPDMGAQRAAFGQALHWVYGELVAQRAEEPVAFLAQLGRDHRKYGVLPTQ
MAV_4795|M.avium_104                PPEMGAQRVAFGHALHWVYGELVARRAQEPVAFLAQLGRDHRKYGVLPRH
MMAR_0644|M.marinum_M               PPEMSGQRAAFTRALHWVYSELVAQRAEEPIAFLAQLGRDHRKYGVQPTQ
MUL_0128|M.ulcerans_Agy99           PPEMSGQRAAFTRALHWVYSELVAQCAEEPIAFLAQLGRDHRKYGVQPTQ
MAB_4269|M.abscessus_ATCC_1997      PADMSAQREHFRQALQFVLWEMASYRTEGLVNFLAQLGRDHRKFGATDSQ
                                    *.::  **  * ..: ::  *: :  :.  : ***********:*.   :

TH_2358|M.thermoresistible__bu      YDTMHEALYTTLRDHLN----DRWTDRLAEAAHDAVTLFTGVMRGAAEAE
MSMEG_0719|M.smegmatis_MC2_155      YDSMQSALYGALKARLA----DRWTDRLAAATRDAVALFIGVMRGAADAE
Mflv_0255|M.gilvum_PYR-GCK          YAGLQDALLAAVRTTLT----DRWDARLEEAATDVVTLAVGVMSGAGEAE
Mvan_0639|M.vanbaalenii_PYR-1       YATLQDALLTTLRKALV----EQWDRRLAEAVDDVVQLVVGVMSGAADAE
Mb0392|M.bovis_AF2122/97            YDTLRRALYTTLRDYLGHPSRGAWTDAVDEAAGQSLNLIIGVMSGAADAD
Rv0385|M.tuberculosis_H37Rv         YDTLRRALYTTLRDYLGHPSRGAWTDAVDEAAGQSLNLIIGVMSGAADAD
MAV_4795|M.avium_104                YQTLGRALLATLRSHL----DAAWTDAVEDAARTSLNLITGVMSGAADAD
MMAR_0644|M.marinum_M               YETLRRALQTTLRSHLG----SSWTDSVARAAEQSLNLIVGVMSGAADSE
MUL_0128|M.ulcerans_Agy99           YETLRRALQTTLRSHLG----SSWTDSVARAAEQSLNLIVGVMSGAADSE
MAB_4269|M.abscessus_ATCC_1997      YDTMRQALLDTTREVLQ----PIWDQRMEATATEVYTVMIEVMRSAAASD
                                    *  :  **  : :  *       *   :  :.     :   ** .*. ::

TH_2358|M.thermoresistible__bu      QGPPYCDGTVVEHLRVGRDVSVVRLQLDRPLFYHPGQYVTVQVPQWPRRW
MSMEG_0719|M.smegmatis_MC2_155      ESPAYCDGTVVETHRLTRDVSVIRLQLDEPLFYHSGQYVTVQVPQWPRRW
Mflv_0255|M.gilvum_PYR-GCK          TAPPFCDGTVLEHLRPTRDVSVIRLKMDHHIDYHAGQYVSVQVPQWPRRW
Mvan_0639|M.vanbaalenii_PYR-1       TSPPFCDGTVLEHLRPARDISVIRLKMDHALAYHPGQYVPVQVPQWPRRW
Mb0392|M.bovis_AF2122/97            DAPAWWDGTVVEHIRVSRDLAVARLQLDRPLHYYPGQYVNVHVPQCPRRW
Rv0385|M.tuberculosis_H37Rv         DAPAWWDGTVVEHIRVSRDLAVARLQLDRPLHYYPGQYVNVHVPQCPRRW
MAV_4795|M.avium_104                EGPAWWDGTVIGHLRVSRDLAVVRLRLDQPMPYHPGQYVNVQVPQCPRRW
MMAR_0644|M.marinum_M               DGPAWWDATVIEHIPASRDLAVIRLQLDHPMPYHPGQYVNVQVPQCPRRW
MUL_0128|M.ulcerans_Agy99           DGPAWSDATVIEHIPASRDLAVIRLQLDHPMPYHPGQYVNVQVPQCPRRW
MAB_4269|M.abscessus_ATCC_1997      IGQPWWDGKVIEFHRTSRDLALIRLKLNAPMPYHCGQYVHVQVPQSPRNW
                                     . .: *..*:      **::: **:::  : *: **** *:*** **.*

TH_2358|M.thermoresistible__bu      RYLSPAIPADRSGAIEFHIRSVIGGMVSTAIVNETRPGDRWRISHPHGSL
MSMEG_0719|M.smegmatis_MC2_155      RYLSPAIPSDRSGAIEFHVRSVTGGMVSTAIVNETRHGDRWRVSSPHGAL
Mflv_0255|M.gilvum_PYR-GCK          RFLSPAIPADPQGYVEFHVRSVAGGMVSTTILGETRPGDRWRLAAPHGAM
Mvan_0639|M.vanbaalenii_PYR-1       RYLSPAIPADPQGYLEFHIRSVAGGMVSTAIVGEARPGDRWRVSNPHGAM
Mb0392|M.bovis_AF2122/97            RYLSPAIPADPNGRIEFHVRVVPGGLVSNAIVGETRPGDRWRLSGPHGAF
Rv0385|M.tuberculosis_H37Rv         RYLSPAIPADPNGRIEFHVRVVPGGLVSNAIVGETRPGDRWRLSGPHGAF
MAV_4795|M.avium_104                RYLSPAIPADPGCGIEFHVRLVPGGLVSTAIVNETRPGDRWRLSSPHGGL
MMAR_0644|M.marinum_M               RYLSPAIPADLEGRIEFHVRVVPGGLVSTAMVNETRTGDRWRLASPHGGL
MUL_0128|M.ulcerans_Agy99           RYLSPAIPADLEGRIEFHVRVVPGGLVSTAMVNETRTGDRWRLASPHGGL
MAB_4269|M.abscessus_ATCC_1997      RYLSLAIPPDPEGYIEFHVRAVPGGLVSGDIVNKTKVGDTWRISPPLGAL
                                    *:** ***.*    :***:* * **:**  ::.::: ** **:: * *.:

TH_2358|M.thermoresistible__bu      HIDRDGGDVLMVAGSTGLAPLRTLIMDLTRFGVNPRVHLFFGARYPCDLY
MSMEG_0719|M.smegmatis_MC2_155      EVNRSGEDVLMVAGSTGLAPLRALIMDMTLHAENPRVHLFFGGRFPCDLY
Mflv_0255|M.gilvum_PYR-GCK          HVDREAGDVLMVAGSTGLAPLRALIMDMCRFAANPRVHLFFGAKYPCELY
Mvan_0639|M.vanbaalenii_PYR-1       EIDRDGGDVLMVAGSTGLAPLRTLIMDLARFSQNPRVHLFFGAKYPCELY
Mb0392|M.bovis_AF2122/97            RVDRDGGDVLMVAGSTGLAPLRALIIDLSRFAVNPRVHLFFGARYACELY
Rv0385|M.tuberculosis_H37Rv         RVDRDGGDVLMVAGSTGLAPLRALIIDLSRFAVNPRVHLFFGARYACELY
MAV_4795|M.avium_104                RVDRDGGDVLMVAGSTGLAPLRALIMDLSRFAVNPRVHLFFGARYRCELY
MMAR_0644|M.marinum_M               HVDRTGGDVLMVAGSTGLAPLRALILDMGRFVENPRVHLFFGARYFCELY
MUL_0128|M.ulcerans_Agy99           HVDRTGGDVLMVAGSTGLAPLRALILDMGRFVENPRVHLFFGARYFCELY
MAB_4269|M.abscessus_ATCC_1997      SVNRDGGDILMVAGSTGIAPLRCLIMELSQWAENPRVHLFYGARYPQELY
                                     ::* . *:********:**** **:::     *******:*.::  :**

TH_2358|M.thermoresistible__bu      DLKTLWQIASTNPWLSVTPVSEYSVDPPWASEYPDVQPPRGLHVRQTGLL
MSMEG_0719|M.smegmatis_MC2_155      DLKTLWTIASTNPWLSVTPVSEYSTDPPWARDYPDPTPPRGLHVRQTGTL
Mflv_0255|M.gilvum_PYR-GCK          DLPTLWEVASMNPWLSVTPVSEFDFDPPWAAEYPDNRPPRGLHVRQTGRL
Mvan_0639|M.vanbaalenii_PYR-1       DLRTLWEIASTNPWLSVTPVSELNFDPPWAADYPDVTPPRGLHVRQLGLL
Mb0392|M.bovis_AF2122/97            DLPTLWQIAAHNPWLSVSPVSEYNGDPAWAADYPDVSAPRGLHVRQTGRL
Rv0385|M.tuberculosis_H37Rv         DLPTLWQIAAHNPWLSVSPVSEYNGDPAWAADYPDVSAPRGLHVRQTGRL
MAV_4795|M.avium_104                DLPTLWQIASHNPWLSVSPVSEYRADPPWAADYPDVTPPRGLHVHQTGRL
MMAR_0644|M.marinum_M               DLRTLWQVAAHNPWLSVSPVAEYKLDPSWATDYPDVSPPRGLHVRQTGRL
MUL_0128|M.ulcerans_Agy99           DLRTLWHVAAHNPWLSVSPVAEYKLDPSWATDYPDVSPPRGLHVRQTGRL
MAB_4269|M.abscessus_ATCC_1997      DLWTLWHIASTNPWLSVTPVTEYPRNPDWATEYHDPTPPRGLHVRQTGLL
                                    ** *** :*: ******:**:*   :* ** :* *  .******:* * *

TH_2358|M.thermoresistible__bu      PEVVTRYGAWSDRQILICGSPEMVQATKAALIAKGAPPERIQHDPLSY-
MSMEG_0719|M.smegmatis_MC2_155      ADVVTRYGNWGDRQILICGGPQMVEATKAALIAKGAPPERIQHDPLTAR
Mflv_0255|M.gilvum_PYR-GCK          DEVVTRYGSWGDRQILVCGRPEMVAATRSALIAKGAPAERIQHDPLGN-
Mvan_0639|M.vanbaalenii_PYR-1       PEVVTRYGNWSDRQILLSGRPAMVQATKAALITKGAPAERIQHDPLAN-
Mb0392|M.bovis_AF2122/97            PDVVSRYGGWGDRQILICGGPAMVRATKAALIAKGAPPERIQHDPLSR-
Rv0385|M.tuberculosis_H37Rv         PDVVSRYGGWGDRQILICGGPAMVRATKAALIAKGAPPERIQHDPLSR-
MAV_4795|M.avium_104                PEVVTKYGGWGDRQILICGGPRMVAATKAALIAKGAAAQRIQHDPLSR-
MMAR_0644|M.marinum_M               AEVVTNYGNWGDRQILICGGPAMVRTTKAALIAKGAPRERIQHDPLP--
MUL_0128|M.ulcerans_Agy99           AEVVTNYGNWGDRQILICGGPAMVRTTKAALIAKGAPRERIQHDPLP--
MAB_4269|M.abscessus_ATCC_1997      SEVVTAYGGWGDRQILIGGSASMIQATKEALVSRGADASRIQHDPL---
                                     :**: ** *.*****: * . *: :*: **:::**  .*******