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VGLEDRDALRVLRDAFAPQPDLDHKTQSSELVRSFYTNWFSLDSSVRDLFPPEMSGQRAAFTRALHWVYS ELVAQCAEEPIAFLAQLGRDHRKYGVQPTQYETLRRALQTTLRSHLGSSWTDSVARAAEQSLNLIVGVMS GAADSEDGPAWSDATVIEHIPASRDLAVIRLQLDHPMPYHPGQYVNVQVPQCPRRWRYLSPAIPADLEGR IEFHVRVVPGGLVSTAMVNETRTGDRWRLASPHGGLHVDRTGGDVLMVAGSTGLAPLRALILDMGRFVEN PRVHLFFGARYFCELYDLRTLWHVAAHNPWLSVSPVAEYKLDPSWATDYPDVSPPRGLHVRQTGRLAEVV TNYGNWGDRQILICGGPAMVRTTKAALIAKGAPRERIQHDPLP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_0128 | - | - | 100% (393) | monooxygenase |
| M. ulcerans Agy99 | MUL_2889 | - | 1e-14 | 29.63% (216) | oxygenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0392 | - | 1e-180 | 77.02% (396) | hypothetical protein Mb0392 |
| M. gilvum PYR-GCK | Mflv_0255 | - | 1e-147 | 64.32% (384) | oxidoreductase FAD-binding subunit |
| M. tuberculosis H37Rv | Rv0385 | - | 1e-180 | 77.02% (396) | hypothetical protein Rv0385 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4269 | - | 1e-126 | 56.89% (392) | monooxygenase |
| M. marinum M | MMAR_0644 | - | 0.0 | 99.24% (393) | monooxygenase |
| M. avium 104 | MAV_4795 | - | 1e-179 | 76.79% (392) | oxidoreductase FAD-binding subunit |
| M. smegmatis MC2 155 | MSMEG_0719 | - | 1e-150 | 66.75% (382) | flavohemoprotein |
| M. thermoresistible (build 8) | TH_2358 | - | 1e-159 | 67.09% (392) | PROBABLE MONOOXYGENASE |
| M. vanbaalenii PYR-1 | Mvan_0639 | - | 1e-152 | 64.80% (392) | oxidoreductase FAD-binding subunit |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0255|M.gilvum_PYR-GCK --------MRILREAFEPGPGSE------RLVGEFYTRWFAADLTARDLF
Mvan_0639|M.vanbaalenii_PYR-1 MGLEDRESMRILRDALDLDLGSE------ALIGDFHTRWFAADLSARDLF
MSMEG_0719|M.smegmatis_MC2_155 ----------MLRAAVDPANDSD------PLIRDFYTNWFAADLSVRDLF
TH_2358|M.thermoresistible__bu VGLDDGESLRTLRAAVDPANGSD------ELIRTFYTRWFAADLSARDLF
MUL_0128|M.ulcerans_Agy99 MGLEDRDALRVLRDAFAPQPDLDHKTQSSELVRSFYTNWFSLDSSVRDLF
MMAR_0644|M.marinum_M MGLEDRDALRVLRDAFAPQPDLDHKTQSSELVRSFYTNWFSLDSSVRDLF
Mb0392|M.bovis_AF2122/97 MGLEDRDALRVLQNAFKL-DDP-------ELVRRFYAHWFALDASVRDLF
Rv0385|M.tuberculosis_H37Rv MGLEDRDALRVLQNAFKL-DDP-------ELVRRFYAHWFALDASVRDLF
MAV_4795|M.avium_104 MSLEDADALRVLRDAFAP-CDAGRPGDSGDLVHRFYTHWFALDPSVRDLF
MAB_4269|M.abscessus_ATCC_1997 MGLEDVEALHDLVGGVELSGNK--------LVRSFYSRWFAIDPTVGDLF
* .. . *: *::.**: * :. ***
Mflv_0255|M.gilvum_PYR-GCK PPDMAGQRQVFAHAMRWLCDELIAQRAEEPVAFLAQLGRDHRKYGVTPEH
Mvan_0639|M.vanbaalenii_PYR-1 PPDLEKQRQVFAQALCWLCDELIAQRAEEPVAFLAQLGRDHRKYGVTQSH
MSMEG_0719|M.smegmatis_MC2_155 PPEMAEQRRVFAHALTWLFGELIAQRAEDPITFLAQLGRDHRKYGVTQQH
TH_2358|M.thermoresistible__bu PPDMAAQRAAFAEVLTWLLGELIAQRAHEPVAFLAQLGRDHRKYGVTQAH
MUL_0128|M.ulcerans_Agy99 PPEMSGQRAAFTRALHWVYSELVAQCAEEPIAFLAQLGRDHRKYGVQPTQ
MMAR_0644|M.marinum_M PPEMSGQRAAFTRALHWVYSELVAQRAEEPIAFLAQLGRDHRKYGVQPTQ
Mb0392|M.bovis_AF2122/97 PPDMGAQRAAFGQALHWVYGELVAQRAEEPVAFLAQLGRDHRKYGVLPTQ
Rv0385|M.tuberculosis_H37Rv PPDMGAQRAAFGQALHWVYGELVAQRAEEPVAFLAQLGRDHRKYGVLPTQ
MAV_4795|M.avium_104 PPEMGAQRVAFGHALHWVYGELVARRAQEPVAFLAQLGRDHRKYGVLPRH
MAB_4269|M.abscessus_ATCC_1997 PADMSAQREHFRQALQFVLWEMASYRTEGLVNFLAQLGRDHRKFGATDSQ
*.:: ** * ..: :: *: : :. : ***********:*. :
Mflv_0255|M.gilvum_PYR-GCK YAGLQDALLAAVRTTLT----DRWDARLEEAATDVVTLAVGVMSGAGEAE
Mvan_0639|M.vanbaalenii_PYR-1 YATLQDALLTTLRKALV----EQWDRRLAEAVDDVVQLVVGVMSGAADAE
MSMEG_0719|M.smegmatis_MC2_155 YDSMQSALYGALKARLA----DRWTDRLAAATRDAVALFIGVMRGAADAE
TH_2358|M.thermoresistible__bu YDTMHEALYTTLRDHLN----DRWTDRLAEAAHDAVTLFTGVMRGAAEAE
MUL_0128|M.ulcerans_Agy99 YETLRRALQTTLRSHLG----SSWTDSVARAAEQSLNLIVGVMSGAADSE
MMAR_0644|M.marinum_M YETLRRALQTTLRSHLG----SSWTDSVARAAEQSLNLIVGVMSGAADSE
Mb0392|M.bovis_AF2122/97 YDTLRRALYTTLRDYLGHPSRGAWTDAVDEAAGQSLNLIIGVMSGAADAD
Rv0385|M.tuberculosis_H37Rv YDTLRRALYTTLRDYLGHPSRGAWTDAVDEAAGQSLNLIIGVMSGAADAD
MAV_4795|M.avium_104 YQTLGRALLATLRSHL----DAAWTDAVEDAARTSLNLITGVMSGAADAD
MAB_4269|M.abscessus_ATCC_1997 YDTMRQALLDTTREVLQ----PIWDQRMEATATEVYTVMIEVMRSAAASD
* : ** : : * * : :. : ** .*. ::
Mflv_0255|M.gilvum_PYR-GCK TAPPFCDGTVLEHLRPTRDVSVIRLKMDHHIDYHAGQYVSVQVPQWPRRW
Mvan_0639|M.vanbaalenii_PYR-1 TSPPFCDGTVLEHLRPARDISVIRLKMDHALAYHPGQYVPVQVPQWPRRW
MSMEG_0719|M.smegmatis_MC2_155 ESPAYCDGTVVETHRLTRDVSVIRLQLDEPLFYHSGQYVTVQVPQWPRRW
TH_2358|M.thermoresistible__bu QGPPYCDGTVVEHLRVGRDVSVVRLQLDRPLFYHPGQYVTVQVPQWPRRW
MUL_0128|M.ulcerans_Agy99 DGPAWSDATVIEHIPASRDLAVIRLQLDHPMPYHPGQYVNVQVPQCPRRW
MMAR_0644|M.marinum_M DGPAWWDATVIEHIPASRDLAVIRLQLDHPMPYHPGQYVNVQVPQCPRRW
Mb0392|M.bovis_AF2122/97 DAPAWWDGTVVEHIRVSRDLAVARLQLDRPLHYYPGQYVNVHVPQCPRRW
Rv0385|M.tuberculosis_H37Rv DAPAWWDGTVVEHIRVSRDLAVARLQLDRPLHYYPGQYVNVHVPQCPRRW
MAV_4795|M.avium_104 EGPAWWDGTVIGHLRVSRDLAVVRLRLDQPMPYHPGQYVNVQVPQCPRRW
MAB_4269|M.abscessus_ATCC_1997 IGQPWWDGKVIEFHRTSRDLALIRLKLNAPMPYHCGQYVHVQVPQSPRNW
. .: *..*: **::: **::: : *: **** *:*** **.*
Mflv_0255|M.gilvum_PYR-GCK RFLSPAIPADPQGYVEFHVRSVAGGMVSTTILGETRPGDRWRLAAPHGAM
Mvan_0639|M.vanbaalenii_PYR-1 RYLSPAIPADPQGYLEFHIRSVAGGMVSTAIVGEARPGDRWRVSNPHGAM
MSMEG_0719|M.smegmatis_MC2_155 RYLSPAIPSDRSGAIEFHVRSVTGGMVSTAIVNETRHGDRWRVSSPHGAL
TH_2358|M.thermoresistible__bu RYLSPAIPADRSGAIEFHIRSVIGGMVSTAIVNETRPGDRWRISHPHGSL
MUL_0128|M.ulcerans_Agy99 RYLSPAIPADLEGRIEFHVRVVPGGLVSTAMVNETRTGDRWRLASPHGGL
MMAR_0644|M.marinum_M RYLSPAIPADLEGRIEFHVRVVPGGLVSTAMVNETRTGDRWRLASPHGGL
Mb0392|M.bovis_AF2122/97 RYLSPAIPADPNGRIEFHVRVVPGGLVSNAIVGETRPGDRWRLSGPHGAF
Rv0385|M.tuberculosis_H37Rv RYLSPAIPADPNGRIEFHVRVVPGGLVSNAIVGETRPGDRWRLSGPHGAF
MAV_4795|M.avium_104 RYLSPAIPADPGCGIEFHVRLVPGGLVSTAIVNETRPGDRWRLSSPHGGL
MAB_4269|M.abscessus_ATCC_1997 RYLSLAIPPDPEGYIEFHVRAVPGGLVSGDIVNKTKVGDTWRISPPLGAL
*:** ***.* :***:* * **:** ::.::: ** **:: * *.:
Mflv_0255|M.gilvum_PYR-GCK HVDREAGDVLMVAGSTGLAPLRALIMDMCRFAANPRVHLFFGAKYPCELY
Mvan_0639|M.vanbaalenii_PYR-1 EIDRDGGDVLMVAGSTGLAPLRTLIMDLARFSQNPRVHLFFGAKYPCELY
MSMEG_0719|M.smegmatis_MC2_155 EVNRSGEDVLMVAGSTGLAPLRALIMDMTLHAENPRVHLFFGGRFPCDLY
TH_2358|M.thermoresistible__bu HIDRDGGDVLMVAGSTGLAPLRTLIMDLTRFGVNPRVHLFFGARYPCDLY
MUL_0128|M.ulcerans_Agy99 HVDRTGGDVLMVAGSTGLAPLRALILDMGRFVENPRVHLFFGARYFCELY
MMAR_0644|M.marinum_M HVDRTGGDVLMVAGSTGLAPLRALILDMGRFVENPRVHLFFGARYFCELY
Mb0392|M.bovis_AF2122/97 RVDRDGGDVLMVAGSTGLAPLRALIIDLSRFAVNPRVHLFFGARYACELY
Rv0385|M.tuberculosis_H37Rv RVDRDGGDVLMVAGSTGLAPLRALIIDLSRFAVNPRVHLFFGARYACELY
MAV_4795|M.avium_104 RVDRDGGDVLMVAGSTGLAPLRALIMDLSRFAVNPRVHLFFGARYRCELY
MAB_4269|M.abscessus_ATCC_1997 SVNRDGGDILMVAGSTGIAPLRCLIMELSQWAENPRVHLFYGARYPQELY
::* . *:********:**** **::: *******:*.:: :**
Mflv_0255|M.gilvum_PYR-GCK DLPTLWEVASMNPWLSVTPVSEFDFDPPWAAEYPDNRPPRGLHVRQTGRL
Mvan_0639|M.vanbaalenii_PYR-1 DLRTLWEIASTNPWLSVTPVSELNFDPPWAADYPDVTPPRGLHVRQLGLL
MSMEG_0719|M.smegmatis_MC2_155 DLKTLWTIASTNPWLSVTPVSEYSTDPPWARDYPDPTPPRGLHVRQTGTL
TH_2358|M.thermoresistible__bu DLKTLWQIASTNPWLSVTPVSEYSVDPPWASEYPDVQPPRGLHVRQTGLL
MUL_0128|M.ulcerans_Agy99 DLRTLWHVAAHNPWLSVSPVAEYKLDPSWATDYPDVSPPRGLHVRQTGRL
MMAR_0644|M.marinum_M DLRTLWQVAAHNPWLSVSPVAEYKLDPSWATDYPDVSPPRGLHVRQTGRL
Mb0392|M.bovis_AF2122/97 DLPTLWQIAAHNPWLSVSPVSEYNGDPAWAADYPDVSAPRGLHVRQTGRL
Rv0385|M.tuberculosis_H37Rv DLPTLWQIAAHNPWLSVSPVSEYNGDPAWAADYPDVSAPRGLHVRQTGRL
MAV_4795|M.avium_104 DLPTLWQIASHNPWLSVSPVSEYRADPPWAADYPDVTPPRGLHVHQTGRL
MAB_4269|M.abscessus_ATCC_1997 DLWTLWHIASTNPWLSVTPVTEYPRNPDWATEYHDPTPPRGLHVRQTGLL
** *** :*: ******:**:* :* ** :* * .******:* * *
Mflv_0255|M.gilvum_PYR-GCK DEVVTRYGSWGDRQILVCGRPEMVAATRSALIAKGAPAERIQHDPLGN-
Mvan_0639|M.vanbaalenii_PYR-1 PEVVTRYGNWSDRQILLSGRPAMVQATKAALITKGAPAERIQHDPLAN-
MSMEG_0719|M.smegmatis_MC2_155 ADVVTRYGNWGDRQILICGGPQMVEATKAALIAKGAPPERIQHDPLTAR
TH_2358|M.thermoresistible__bu PEVVTRYGAWSDRQILICGSPEMVQATKAALIAKGAPPERIQHDPLSY-
MUL_0128|M.ulcerans_Agy99 AEVVTNYGNWGDRQILICGGPAMVRTTKAALIAKGAPRERIQHDPLP--
MMAR_0644|M.marinum_M AEVVTNYGNWGDRQILICGGPAMVRTTKAALIAKGAPRERIQHDPLP--
Mb0392|M.bovis_AF2122/97 PDVVSRYGGWGDRQILICGGPAMVRATKAALIAKGAPPERIQHDPLSR-
Rv0385|M.tuberculosis_H37Rv PDVVSRYGGWGDRQILICGGPAMVRATKAALIAKGAPPERIQHDPLSR-
MAV_4795|M.avium_104 PEVVTKYGGWGDRQILICGGPRMVAATKAALIAKGAAAQRIQHDPLSR-
MAB_4269|M.abscessus_ATCC_1997 SEVVTAYGGWGDRQILIGGSASMIQATKEALVSRGADASRIQHDPL---
:**: ** *.*****: * . *: :*: **:::** .*******