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VGLEDRDALRVLQNAFKLDDPELVRRFYAHWFALDASVRDLFPPDMGAQRAAFGQALHWVYGELVAQRAE EPVAFLAQLGRDHRKYGVLPTQYDTLRRALYTTLRDYLGHPSRGAWTDAVDEAAGQSLNLIIGVMSGAAD ADDAPAWWDGTVVEHIRVSRDLAVARLQLDRPLHYYPGQYVNVHVPQCPRRWRYLSPAIPADPNGRIEFH VRVVPGGLVSNAIVGETRPGDRWRLSGPHGAFRVDRDGGDVLMVAGSTGLAPLRALIIDLSRFAVNPRVH LFFGARYACELYDLPTLWQIAAHNPWLSVSPVSEYNGDPAWAADYPDVSAPRGLHVRQTGRLPDVVSRYG GWGDRQILICGGPAMVRATKAALIAKGAPPERIQHDPLSR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0392 | - | - | 100% (390) | hypothetical protein Mb0392 |
| M. bovis AF2122 / 97 | Mb1972 | - | 5e-16 | 30.04% (233) | oxygenase |
| M. bovis AF2122 / 97 | Mb3259c | - | 3e-05 | 27.34% (139) | oxidoreductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0255 | - | 1e-147 | 64.66% (382) | oxidoreductase FAD-binding subunit |
| M. tuberculosis H37Rv | Rv0385 | - | 0.0 | 100.00% (390) | hypothetical protein Rv0385 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4269 | - | 1e-129 | 58.76% (388) | monooxygenase |
| M. marinum M | MMAR_0644 | - | 0.0 | 77.78% (396) | monooxygenase |
| M. avium 104 | MAV_4795 | - | 0.0 | 79.60% (397) | oxidoreductase FAD-binding subunit |
| M. smegmatis MC2 155 | MSMEG_0719 | - | 1e-148 | 67.65% (371) | flavohemoprotein |
| M. thermoresistible (build 8) | TH_2358 | - | 1e-164 | 70.81% (394) | PROBABLE MONOOXYGENASE |
| M. ulcerans Agy99 | MUL_0128 | - | 1e-180 | 77.02% (396) | monooxygenase |
| M. vanbaalenii PYR-1 | Mvan_0639 | - | 1e-153 | 67.01% (391) | oxidoreductase FAD-binding subunit |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0255|M.gilvum_PYR-GCK --------MRILREAFEPGPGSE------RLVGEFYTRWFAADLTARDLF
Mvan_0639|M.vanbaalenii_PYR-1 MGLEDRESMRILRDALDLDLGSE------ALIGDFHTRWFAADLSARDLF
MSMEG_0719|M.smegmatis_MC2_155 ----------MLRAAVDPANDSD------PLIRDFYTNWFAADLSVRDLF
TH_2358|M.thermoresistible__bu VGLDDGESLRTLRAAVDPANGSD------ELIRTFYTRWFAADLSARDLF
Mb0392|M.bovis_AF2122/97 MGLEDRDALRVLQNAFKL-DDP-------ELVRRFYAHWFALDASVRDLF
Rv0385|M.tuberculosis_H37Rv MGLEDRDALRVLQNAFKL-DDP-------ELVRRFYAHWFALDASVRDLF
MAV_4795|M.avium_104 MSLEDADALRVLRDAFAP-CDAGRPGDSGDLVHRFYTHWFALDPSVRDLF
MMAR_0644|M.marinum_M MGLEDRDALRVLRDAFAPQPDLDHKTQSSELVRSFYTNWFSLDSSVRDLF
MUL_0128|M.ulcerans_Agy99 MGLEDRDALRVLRDAFAPQPDLDHKTQSSELVRSFYTNWFSLDSSVRDLF
MAB_4269|M.abscessus_ATCC_1997 MGLEDVEALHDLVGGVELSGNK--------LVRSFYSRWFAIDPTVGDLF
* .. . *: *::.**: * :. ***
Mflv_0255|M.gilvum_PYR-GCK PPDMAGQRQVFAHAMRWLCDELIAQRAEEPVAFLAQLGRDHRKYGVTPEH
Mvan_0639|M.vanbaalenii_PYR-1 PPDLEKQRQVFAQALCWLCDELIAQRAEEPVAFLAQLGRDHRKYGVTQSH
MSMEG_0719|M.smegmatis_MC2_155 PPEMAEQRRVFAHALTWLFGELIAQRAEDPITFLAQLGRDHRKYGVTQQH
TH_2358|M.thermoresistible__bu PPDMAAQRAAFAEVLTWLLGELIAQRAHEPVAFLAQLGRDHRKYGVTQAH
Mb0392|M.bovis_AF2122/97 PPDMGAQRAAFGQALHWVYGELVAQRAEEPVAFLAQLGRDHRKYGVLPTQ
Rv0385|M.tuberculosis_H37Rv PPDMGAQRAAFGQALHWVYGELVAQRAEEPVAFLAQLGRDHRKYGVLPTQ
MAV_4795|M.avium_104 PPEMGAQRVAFGHALHWVYGELVARRAQEPVAFLAQLGRDHRKYGVLPRH
MMAR_0644|M.marinum_M PPEMSGQRAAFTRALHWVYSELVAQRAEEPIAFLAQLGRDHRKYGVQPTQ
MUL_0128|M.ulcerans_Agy99 PPEMSGQRAAFTRALHWVYSELVAQCAEEPIAFLAQLGRDHRKYGVQPTQ
MAB_4269|M.abscessus_ATCC_1997 PADMSAQREHFRQALQFVLWEMASYRTEGLVNFLAQLGRDHRKFGATDSQ
*.:: ** * ..: :: *: : :. : ***********:*. :
Mflv_0255|M.gilvum_PYR-GCK YAGLQDALLAAVRTTLT----DRWDARLEEAATDVVTLAVGVMSGAGEAE
Mvan_0639|M.vanbaalenii_PYR-1 YATLQDALLTTLRKALV----EQWDRRLAEAVDDVVQLVVGVMSGAADAE
MSMEG_0719|M.smegmatis_MC2_155 YDSMQSALYGALKARLA----DRWTDRLAAATRDAVALFIGVMRGAADAE
TH_2358|M.thermoresistible__bu YDTMHEALYTTLRDHLN----DRWTDRLAEAAHDAVTLFTGVMRGAAEAE
Mb0392|M.bovis_AF2122/97 YDTLRRALYTTLRDYLGHPSRGAWTDAVDEAAGQSLNLIIGVMSGAADAD
Rv0385|M.tuberculosis_H37Rv YDTLRRALYTTLRDYLGHPSRGAWTDAVDEAAGQSLNLIIGVMSGAADAD
MAV_4795|M.avium_104 YQTLGRALLATLRSHL----DAAWTDAVEDAARTSLNLITGVMSGAADAD
MMAR_0644|M.marinum_M YETLRRALQTTLRSHLG----SSWTDSVARAAEQSLNLIVGVMSGAADSE
MUL_0128|M.ulcerans_Agy99 YETLRRALQTTLRSHLG----SSWTDSVARAAEQSLNLIVGVMSGAADSE
MAB_4269|M.abscessus_ATCC_1997 YDTMRQALLDTTREVLQ----PIWDQRMEATATEVYTVMIEVMRSAAASD
* : ** : : * * : :. : ** .*. ::
Mflv_0255|M.gilvum_PYR-GCK TAPPFCDGTVLEHLRPTRDVSVIRLKMDHHIDYHAGQYVSVQVPQWPRRW
Mvan_0639|M.vanbaalenii_PYR-1 TSPPFCDGTVLEHLRPARDISVIRLKMDHALAYHPGQYVPVQVPQWPRRW
MSMEG_0719|M.smegmatis_MC2_155 ESPAYCDGTVVETHRLTRDVSVIRLQLDEPLFYHSGQYVTVQVPQWPRRW
TH_2358|M.thermoresistible__bu QGPPYCDGTVVEHLRVGRDVSVVRLQLDRPLFYHPGQYVTVQVPQWPRRW
Mb0392|M.bovis_AF2122/97 DAPAWWDGTVVEHIRVSRDLAVARLQLDRPLHYYPGQYVNVHVPQCPRRW
Rv0385|M.tuberculosis_H37Rv DAPAWWDGTVVEHIRVSRDLAVARLQLDRPLHYYPGQYVNVHVPQCPRRW
MAV_4795|M.avium_104 EGPAWWDGTVIGHLRVSRDLAVVRLRLDQPMPYHPGQYVNVQVPQCPRRW
MMAR_0644|M.marinum_M DGPAWWDATVIEHIPASRDLAVIRLQLDHPMPYHPGQYVNVQVPQCPRRW
MUL_0128|M.ulcerans_Agy99 DGPAWSDATVIEHIPASRDLAVIRLQLDHPMPYHPGQYVNVQVPQCPRRW
MAB_4269|M.abscessus_ATCC_1997 IGQPWWDGKVIEFHRTSRDLALIRLKLNAPMPYHCGQYVHVQVPQSPRNW
. .: *..*: **::: **::: : *: **** *:*** **.*
Mflv_0255|M.gilvum_PYR-GCK RFLSPAIPADPQGYVEFHVRSVAGGMVSTTILGETRPGDRWRLAAPHGAM
Mvan_0639|M.vanbaalenii_PYR-1 RYLSPAIPADPQGYLEFHIRSVAGGMVSTAIVGEARPGDRWRVSNPHGAM
MSMEG_0719|M.smegmatis_MC2_155 RYLSPAIPSDRSGAIEFHVRSVTGGMVSTAIVNETRHGDRWRVSSPHGAL
TH_2358|M.thermoresistible__bu RYLSPAIPADRSGAIEFHIRSVIGGMVSTAIVNETRPGDRWRISHPHGSL
Mb0392|M.bovis_AF2122/97 RYLSPAIPADPNGRIEFHVRVVPGGLVSNAIVGETRPGDRWRLSGPHGAF
Rv0385|M.tuberculosis_H37Rv RYLSPAIPADPNGRIEFHVRVVPGGLVSNAIVGETRPGDRWRLSGPHGAF
MAV_4795|M.avium_104 RYLSPAIPADPGCGIEFHVRLVPGGLVSTAIVNETRPGDRWRLSSPHGGL
MMAR_0644|M.marinum_M RYLSPAIPADLEGRIEFHVRVVPGGLVSTAMVNETRTGDRWRLASPHGGL
MUL_0128|M.ulcerans_Agy99 RYLSPAIPADLEGRIEFHVRVVPGGLVSTAMVNETRTGDRWRLASPHGGL
MAB_4269|M.abscessus_ATCC_1997 RYLSLAIPPDPEGYIEFHVRAVPGGLVSGDIVNKTKVGDTWRISPPLGAL
*:** ***.* :***:* * **:** ::.::: ** **:: * *.:
Mflv_0255|M.gilvum_PYR-GCK HVDREAGDVLMVAGSTGLAPLRALIMDMCRFAANPRVHLFFGAKYPCELY
Mvan_0639|M.vanbaalenii_PYR-1 EIDRDGGDVLMVAGSTGLAPLRTLIMDLARFSQNPRVHLFFGAKYPCELY
MSMEG_0719|M.smegmatis_MC2_155 EVNRSGEDVLMVAGSTGLAPLRALIMDMTLHAENPRVHLFFGGRFPCDLY
TH_2358|M.thermoresistible__bu HIDRDGGDVLMVAGSTGLAPLRTLIMDLTRFGVNPRVHLFFGARYPCDLY
Mb0392|M.bovis_AF2122/97 RVDRDGGDVLMVAGSTGLAPLRALIIDLSRFAVNPRVHLFFGARYACELY
Rv0385|M.tuberculosis_H37Rv RVDRDGGDVLMVAGSTGLAPLRALIIDLSRFAVNPRVHLFFGARYACELY
MAV_4795|M.avium_104 RVDRDGGDVLMVAGSTGLAPLRALIMDLSRFAVNPRVHLFFGARYRCELY
MMAR_0644|M.marinum_M HVDRTGGDVLMVAGSTGLAPLRALILDMGRFVENPRVHLFFGARYFCELY
MUL_0128|M.ulcerans_Agy99 HVDRTGGDVLMVAGSTGLAPLRALILDMGRFVENPRVHLFFGARYFCELY
MAB_4269|M.abscessus_ATCC_1997 SVNRDGGDILMVAGSTGIAPLRCLIMELSQWAENPRVHLFYGARYPQELY
::* . *:********:**** **::: *******:*.:: :**
Mflv_0255|M.gilvum_PYR-GCK DLPTLWEVASMNPWLSVTPVSEFDFDPPWAAEYPDNRPPRGLHVRQTGRL
Mvan_0639|M.vanbaalenii_PYR-1 DLRTLWEIASTNPWLSVTPVSELNFDPPWAADYPDVTPPRGLHVRQLGLL
MSMEG_0719|M.smegmatis_MC2_155 DLKTLWTIASTNPWLSVTPVSEYSTDPPWARDYPDPTPPRGLHVRQTGTL
TH_2358|M.thermoresistible__bu DLKTLWQIASTNPWLSVTPVSEYSVDPPWASEYPDVQPPRGLHVRQTGLL
Mb0392|M.bovis_AF2122/97 DLPTLWQIAAHNPWLSVSPVSEYNGDPAWAADYPDVSAPRGLHVRQTGRL
Rv0385|M.tuberculosis_H37Rv DLPTLWQIAAHNPWLSVSPVSEYNGDPAWAADYPDVSAPRGLHVRQTGRL
MAV_4795|M.avium_104 DLPTLWQIASHNPWLSVSPVSEYRADPPWAADYPDVTPPRGLHVHQTGRL
MMAR_0644|M.marinum_M DLRTLWQVAAHNPWLSVSPVAEYKLDPSWATDYPDVSPPRGLHVRQTGRL
MUL_0128|M.ulcerans_Agy99 DLRTLWHVAAHNPWLSVSPVAEYKLDPSWATDYPDVSPPRGLHVRQTGRL
MAB_4269|M.abscessus_ATCC_1997 DLWTLWHIASTNPWLSVTPVTEYPRNPDWATEYHDPTPPRGLHVRQTGLL
** *** :*: ******:**:* :* ** :* * .******:* * *
Mflv_0255|M.gilvum_PYR-GCK DEVVTRYGSWGDRQILVCGRPEMVAATRSALIAKGAPAERIQHDPLGN-
Mvan_0639|M.vanbaalenii_PYR-1 PEVVTRYGNWSDRQILLSGRPAMVQATKAALITKGAPAERIQHDPLAN-
MSMEG_0719|M.smegmatis_MC2_155 ADVVTRYGNWGDRQILICGGPQMVEATKAALIAKGAPPERIQHDPLTAR
TH_2358|M.thermoresistible__bu PEVVTRYGAWSDRQILICGSPEMVQATKAALIAKGAPPERIQHDPLSY-
Mb0392|M.bovis_AF2122/97 PDVVSRYGGWGDRQILICGGPAMVRATKAALIAKGAPPERIQHDPLSR-
Rv0385|M.tuberculosis_H37Rv PDVVSRYGGWGDRQILICGGPAMVRATKAALIAKGAPPERIQHDPLSR-
MAV_4795|M.avium_104 PEVVTKYGGWGDRQILICGGPRMVAATKAALIAKGAAAQRIQHDPLSR-
MMAR_0644|M.marinum_M AEVVTNYGNWGDRQILICGGPAMVRTTKAALIAKGAPRERIQHDPLP--
MUL_0128|M.ulcerans_Agy99 AEVVTNYGNWGDRQILICGGPAMVRTTKAALIAKGAPRERIQHDPLP--
MAB_4269|M.abscessus_ATCC_1997 SEVVTAYGGWGDRQILIGGSASMIQATKEALVSRGADASRIQHDPL---
:**: ** *.*****: * . *: :*: **:::** .*******