For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
RGDPTPRSARGVYGISVASELSGIPPQTLRHYERRGLLTPARSDGGTRRYSDDDLARLKRISQLVDQGVN LVGVARILDLESKNDQLKADYSALELLNAQLKTRQNSERAAAPRQGRGEARREAV*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2720 | - | - | 100% (126) | transcriptional regulator, MerR family protein |
| M. avium 104 | MAV_1993 | - | 2e-41 | 67.50% (120) | HspR protein |
| M. avium 104 | MAV_4105 | - | 3e-29 | 68.04% (97) | transcriptional regulator, MerR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0361 | hspR | 2e-16 | 42.57% (101) | HEAT shock protein transcriptional regulator HspR |
| M. gilvum PYR-GCK | Mflv_0257 | - | 5e-15 | 40.74% (108) | MerR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0353 | hspR | 2e-16 | 42.57% (101) | HEAT shock protein transcriptional repressor HspR |
| M. leprae Br4923 | MLBr_02493 | hspR | 3e-16 | 37.17% (113) | heat shock regulator |
| M. abscessus ATCC 19977 | MAB_3468 | - | 6e-23 | 58.33% (84) | MerR family transcriptional regulator |
| M. marinum M | MMAR_2990 | hspR_2 | 1e-25 | 52.10% (119) | heat shock protein transcriptional repressor HspR_2 |
| M. smegmatis MC2 155 | MSMEG_0713 | - | 1e-15 | 41.35% (104) | transcriptional regulator, MerR family protein |
| M. thermoresistible (build 8) | TH_2359 | hspR | 2e-16 | 43.56% (101) | PROBABLE HEAT SHOCK PROTEIN TRANSCRIPTIONAL REPRESSOR HSPR |
| M. ulcerans Agy99 | MUL_0596 | hspR | 2e-16 | 44.23% (104) | heat shock protein transcriptional repressor HspR |
| M. vanbaalenii PYR-1 | Mvan_0637 | - | 2e-16 | 39.67% (121) | MerR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0361|M.bovis_AF2122/97 ----------------MAKN--PKD---GESRTFLISVAAELAGMHAQTL
Rv0353|M.tuberculosis_H37Rv ----------------MAKN--PKD---GESRTFLISVAAELAGMHAQTL
MUL_0596|M.ulcerans_Agy99 ----------------MAKN--SRE---GEARTFLISVAAELAGMHAQTL
MLBr_02493|M.leprae_Br4923 ---------------MMTRN--SRDPRQQESRTFLISAAAELAGMHAQTL
Mflv_0257|M.gilvum_PYR-GCK ----------------MSG----RK---EEARTFLISVAAELAGMHAQTL
Mvan_0637|M.vanbaalenii_PYR-1 ----------------MSAGRPSRK---EDARTFLISVAAELAGMHAQTL
MSMEG_0713|M.smegmatis_MC2_155 ----------------MSG---KRN---EEARTFLISVAAELAGMHAQTL
TH_2359|M.thermoresistible__bu ----------------VSRS--KRS--NDDTRTFMISVAAELAGMHAQTL
MAB_3468|M.abscessus_ATCC_1997 MVPEDVLYPSGSPVPRLEGPR-PPELPAPEKGVYGISVAAELSGAATQSL
MMAR_2990|M.marinum_M MADR----------PGHAGG------PAPDVGVYGISVTAELSGIAVQSL
MAV_2720|M.avium_104 ----------------MRGD----PTPRSARGVYGISVASELSGIPPQTL
.: **.::**:* *:*
Mb0361|M.bovis_AF2122/97 RTYDRLGLVSPRRTSGGGRRYSLHDVELLRQVQHLSQDEGVNLAGIKRII
Rv0353|M.tuberculosis_H37Rv RTYDRLGLVSPRRTSGGGRRYSLHDVELLRQVQHLSQDEGVNLAGIKRII
MUL_0596|M.ulcerans_Agy99 RTYDRLGLVSPRRTSGGGRRYSEHDVNLLRQVQQLSQEEGVNLAGIKRII
MLBr_02493|M.leprae_Br4923 RTYDRLGLVSPSRASGGGRRYSQHDVELLRQVQRLSQNEGVNLAGIKRII
Mflv_0257|M.gilvum_PYR-GCK RTYDRLGLVSPQRSSGGGRRYSQRDVDLLREVQRLSQDEGVNLAGIKRII
Mvan_0637|M.vanbaalenii_PYR-1 RTYDRLGLVSPQRSSGGGRRYSQRDVDLLREVQRLSQDEGVNLAGIKRII
MSMEG_0713|M.smegmatis_MC2_155 RTYDRLGLVTPQRTSGGGRRYSERDVDLLREVQRLSQDEGVNLAGIKRII
TH_2359|M.thermoresistible__bu RTYDRLGLVRPKRSPGGGRRYSWRDVELLREVQRLSQDEGVNLAGIKRII
MAB_3468|M.abscessus_ATCC_1997 RLWERHGLLAPSRTEGGTRRYSPEDLIRIRRITTL-VAAGVNIAGIAFIL
MMAR_2990|M.marinum_M RLYERHGLVTPARSEGGTRRYSADDLVRLQRVSVL-IEAGINLAGISRIL
MAV_2720|M.avium_104 RHYERRGLLTPARSDGGTRRYSDDDLARLKRISQL-VDQGVNLVGVARIL
* ::* **: * *: ** **** *: ::.: * *:*:.*: *:
Mb0361|M.bovis_AF2122/97 ELTSQVEALQSRLQEMAEELAVLRANQRREVAVVPKSTALVVWK------
Rv0353|M.tuberculosis_H37Rv ELTSQVEALQSRLQEMAEELAVLRANQRREVAVVPKSTALVVWK------
MUL_0596|M.ulcerans_Agy99 ELTNQVEALQSRLQEMADELETMRAKQRREVALVPRSTALVVWQRAGPAE
MLBr_02493|M.leprae_Br4923 ELTNQVEALQLKLQELTDELVMLRANQRRDLAVVPKSTALVLWQ------
Mflv_0257|M.gilvum_PYR-GCK ELTNQVEALQSRVRELTNEVEHLRSQP------RPKSTALVVWQ------
Mvan_0637|M.vanbaalenii_PYR-1 ELTNQVEALQARVRELSDEVERLRAQP------RPKSTALVVWQ------
MSMEG_0713|M.smegmatis_MC2_155 ELTNQVDALQRRVAELTAEVERLR---------KP-STALVLWQ------
TH_2359|M.thermoresistible__bu ELTNQVEQLQARVKELTQELEQMRSVPRRELAVVPKSTAVVLWK------
MAB_3468|M.abscessus_ATCC_1997 ELEDDNTALRA--AVYD----QQRRHSDTDR-------------------
MMAR_2990|M.marinum_M NLEDDNAALAA--ANCDLL-ASNRSLRDAARAAVRLMNHGRSAE------
MAV_2720|M.avium_104 DLESKNDQLKADYSALELLNAQLKTRQNSERAAAPRQGRGEARR------
:* .. * :
Mb0361|M.bovis_AF2122/97 ------------------PRR----------
Rv0353|M.tuberculosis_H37Rv ------------------PRR----------
MUL_0596|M.ulcerans_Agy99 PAFRHTPPGYGPVPVLKNPERLDPVLKKPEM
MLBr_02493|M.leprae_Br4923 ------------------PRKPR--------
Mflv_0257|M.gilvum_PYR-GCK ------------------PRHQR--------
Mvan_0637|M.vanbaalenii_PYR-1 ------------------PRNQR--------
MSMEG_0713|M.smegmatis_MC2_155 ------------------PRNNRKR------
TH_2359|M.thermoresistible__bu ------------------PRRSGEKT-----
MAB_3468|M.abscessus_ATCC_1997 -------------------------------
MMAR_2990|M.marinum_M ------------------NGEGGDTS-----
MAV_2720|M.avium_104 ------------------EAV----------