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M. tuberculosis H37Rv Rv0353 (hspR)

annotation: PROBABLE HEAT SHOCK PROTEIN TRANSCRIPTIONAL REPRESSOR HSPR (MERR FAMILY)
coordinates: 423639 - 424019
length: 126

MAKNPKDGESRTFLISVAAELAGMHAQTLRTYDRLGLVSPRRTSGGGRRYSLHDVELLRQVQHLSQDEGV
NLAGIKRIIELTSQVEALQSRLQEMAEELAVLRANQRREVAVVPKSTALVVWKPRR
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv0353hspR-100% (126)PROBABLE HEAT SHOCK PROTEIN TRANSCRIPTIONAL REPRESSOR HSPR (MERR FAMILY)
M. tuberculosis H37RvRv3334-2e-0532.32% (99) MerR family transcriptional regulator

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0361hspR3e-66100.00% (126) HEAT shock protein transcriptional regulator HspR
M. gilvum PYR-GCKMflv_0257-2e-4476.92% (117) MerR family transcriptional regulator
M. leprae Br4923MLBr_02493hspR1e-5380.00% (125) heat shock regulator
M. abscessus ATCC 19977MAB_4270c-8e-4775.20% (125) heat shock protein transcriptional regulator HspR
M. marinum MMMAR_0640hspR9e-5887.30% (126) heat shock protein transcriptional repressor HspR
M. avium 104MAV_4805-1e-5482.54% (126) transcriptional regulator, MerR family protein
M. smegmatis MC2 155MSMEG_0713-3e-4070.00% (120) transcriptional regulator, MerR family protein
M. thermoresistible (build 8)TH_2359hspR2e-4776.27% (118) PROBABLE HEAT SHOCK PROTEIN TRANSCRIPTIONAL REPRESSOR HSPR
M. ulcerans Agy99MUL_0596hspR1e-5586.18% (123) heat shock protein transcriptional repressor HspR
M. vanbaalenii PYR-1Mvan_0637-2e-4476.07% (117) MerR family transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_0257|M.gilvum_PYR-GCK          -MSG----------RKEE----ARTFLISVAAELAGMHAQTLRTYDRLGL
Mvan_0637|M.vanbaalenii_PYR-1       -MSAGR------PSRKED----ARTFLISVAAELAGMHAQTLRTYDRLGL
MSMEG_0713|M.smegmatis_MC2_155      -MSG---------KRNEE----ARTFLISVAAELAGMHAQTLRTYDRLGL
MAB_4270c|M.abscessus_ATCC_199      -MTSSQGDGGASRRRQPER--GARTFLISVAAELAGMHAQTLRTYDRLGL
TH_2359|M.thermoresistible__bu      -VSRSK-------RSNDD----TRTFMISVAAELAGMHAQTLRTYDRLGL
MAV_4805|M.avium_104                -MAKNR-------KGHES-----RTFLISVAAELAGMHAQTLRTYDRLGL
Rv0353|M.tuberculosis_H37Rv         -MAK---------NPKD---GESRTFLISVAAELAGMHAQTLRTYDRLGL
Mb0361|M.bovis_AF2122/97            -MAK---------NPKD---GESRTFLISVAAELAGMHAQTLRTYDRLGL
MMAR_0640|M.marinum_M               -MAK---------NSRE---GEARTFLISVAAELAGMHAQTLRTYDRLGL
MUL_0596|M.ulcerans_Agy99           -MAK---------NSRE---GEARTFLISVAAELAGMHAQTLRTYDRLGL
MLBr_02493|M.leprae_Br4923          MMTR---------NSRDPRQQESRTFLISAAAELAGMHAQTLRTYDRLGL
                                     ::            .       ***:**.********************

Mflv_0257|M.gilvum_PYR-GCK          VSPQRSSGGGRRYSQRDVDLLREVQRLSQDEGVNLAGIKRIIELTNQVEA
Mvan_0637|M.vanbaalenii_PYR-1       VSPQRSSGGGRRYSQRDVDLLREVQRLSQDEGVNLAGIKRIIELTNQVEA
MSMEG_0713|M.smegmatis_MC2_155      VTPQRTSGGGRRYSERDVDLLREVQRLSQDEGVNLAGIKRIIELTNQVDA
MAB_4270c|M.abscessus_ATCC_199      VSPERTTGGGRRYSQRDVDLLREVQRLSQDEGVNLAGIKRVIELTNQVEA
TH_2359|M.thermoresistible__bu      VRPKRSPGGGRRYSWRDVELLREVQRLSQDEGVNLAGIKRIIELTNQVEQ
MAV_4805|M.avium_104                VSPQRTSGGGRRYSEHDVDLLREVQRLSQDEGVNLAGIKRIIELTNQVEA
Rv0353|M.tuberculosis_H37Rv         VSPRRTSGGGRRYSLHDVELLRQVQHLSQDEGVNLAGIKRIIELTSQVEA
Mb0361|M.bovis_AF2122/97            VSPRRTSGGGRRYSLHDVELLRQVQHLSQDEGVNLAGIKRIIELTSQVEA
MMAR_0640|M.marinum_M               VSPRRTSGGGRRYSEHDVNLLRQVQQLSQEEGVNLAGIKRIIELTNQVEA
MUL_0596|M.ulcerans_Agy99           VSPRRTSGGGRRYSEHDVNLLRQVQQLSQEEGVNLAGIKRIIELTNQVEA
MLBr_02493|M.leprae_Br4923          VSPSRASGGGRRYSQHDVELLRQVQRLSQNEGVNLAGIKRIIELTNQVEA
                                    * * *:.******* :**:***:**:***:**********:****.**: 

Mflv_0257|M.gilvum_PYR-GCK          LQSRVRELTNEVEHLRSQ-------PRPKSTALVVWQ---PRHQR-----
Mvan_0637|M.vanbaalenii_PYR-1       LQARVRELSDEVERLRAQ-------PRPKSTALVVWQ---PRNQR-----
MSMEG_0713|M.smegmatis_MC2_155      LQRRVAELTAEVERLR----------KP-STALVLWQ---PRNNRKR---
MAB_4270c|M.abscessus_ATCC_199      LQAKLAELTAEVAQLRAATAGREVAVIPKSTAVVVWQ---PRQQR-----
TH_2359|M.thermoresistible__bu      LQARVKELTQELEQMRSVPR-RELAVVPKSTAVVLWK---PRRSGEKT--
MAV_4805|M.avium_104                LQARVKELTEELAQVRAGQR-RDLAVLPKSTALVVWQ---PRKGGTRT--
Rv0353|M.tuberculosis_H37Rv         LQSRLQEMAEELAVLRANQR-REVAVVPKSTALVVWK---PRR-------
Mb0361|M.bovis_AF2122/97            LQSRLQEMAEELAVLRANQR-REVAVVPKSTALVVWK---PRR-------
MMAR_0640|M.marinum_M               LQSRLQEMADELETMRAKQR-REVALVPKSTALVVWQ---PRRPR-----
MUL_0596|M.ulcerans_Agy99           LQSRLQEMADELETMRAKQR-REVALVPRSTALVVWQRAGPAEPAFRHTP
MLBr_02493|M.leprae_Br4923          LQLKLQELTDELVMLRANQR-RDLAVVPKSTALVLWQ---PRKPR-----
                                    ** :: *:: *:  :*           * ***:*:*:   * .       

Mflv_0257|M.gilvum_PYR-GCK          ------------------------
Mvan_0637|M.vanbaalenii_PYR-1       ------------------------
MSMEG_0713|M.smegmatis_MC2_155      ------------------------
MAB_4270c|M.abscessus_ATCC_199      ------------------------
TH_2359|M.thermoresistible__bu      ------------------------
MAV_4805|M.avium_104                ------------------------
Rv0353|M.tuberculosis_H37Rv         ------------------------
Mb0361|M.bovis_AF2122/97            ------------------------
MMAR_0640|M.marinum_M               ------------------------
MUL_0596|M.ulcerans_Agy99           PGYGPVPVLKNPERLDPVLKKPEM
MLBr_02493|M.leprae_Br4923          ------------------------