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M. smegmatis MC2 155 MSMEG_1447 (-)

annotation: transcriptional regulator, MerR family protein
coordinates: 1543239 - 1543640
length: 133

TVPGTDQDLLQIGEVAARTELSVKTIRHYDEVGLVVPSARSAGGFRLYTTDDVRRLMAIRRMKPLGFTLD
EMGRLLDALAVLDKPAATAAERATAAEVVSDCHTRAQEACDRLTRHLAYARELTEQLAKVRG*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_1447--100% (133)transcriptional regulator, MerR family protein
M. smegmatis MC2 155MSMEG_2194-2e-1348.53% (68) MerR-family protein transcriptional regulator
M. smegmatis MC2 155MSMEG_3180-2e-0838.20% (89) transcriptional regulator, MerR family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3367-1e-0940.74% (81) MerR family transcriptional regulator
M. gilvum PYR-GCKMflv_0148-1e-1241.10% (73) MerR family transcriptional regulator
M. tuberculosis H37RvRv3334-1e-0940.74% (81) MerR family transcriptional regulator
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_2309c-9e-0934.12% (85) putative transcriptional regulator
M. marinum MMMAR_0009-2e-1447.14% (70) transcriptional regulator
M. avium 104MAV_3222-6e-1038.61% (101) transcriptional regulator, MerR family protein
M. thermoresistible (build 8)TH_0931soxR9e-0536.23% (69) redox-sensitive transcriptional activator SoxR
M. ulcerans Agy99MUL_0011-2e-1447.14% (70) transcriptional regulator
M. vanbaalenii PYR-1Mvan_1160-8e-4472.00% (125) MerR family transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


MSMEG_1447|M.smegmatis_MC2_155      MTVPGTDQDLLQIGEVAARTELSVKTIRHYDEVGLVVPSARSAGGFRLYT
Mvan_1160|M.vanbaalenii_PYR-1       ------MAELLQIGEVAARTELSVKTIRHYDEVGLVTPSSRSGGGFRLYT
Mb3367|M.bovis_AF2122/97            ----------MKISEVAALTNTSTKTLRFYENSGLLPPPARTASGYRNYG
Rv3334|M.tuberculosis_H37Rv         ----------MKISEVAALTNTSTKTLRFYENSGLLPPPARTASGYRNYG
MMAR_0009|M.marinum_M               -------MDGLTVGQVAERFGITVRTLHHYDEIGLLIPSRRAASGYRVYT
MUL_0011|M.ulcerans_Agy99           -------MDGLTVGQVAERFGITVRTLHHYDEIGLLIPSRRAASGYRVYT
Mflv_0148|M.gilvum_PYR-GCK          -MTQETRMEELTVGEVAKRFGITIRTLHHYDHIGLLTPEQRNASGYRVYT
MAB_2309c|M.abscessus_ATCC_199      ---MKGKTELLPIGEVARRSGIAVSAVRYYADIGLVP-AERTSGNVRVFR
TH_0931|M.thermoresistible__bu      ----MGAHELTPS-EMSARSGVAVSALHFYEREGLIT-SRRTAGNQRRYP
MAV_3222|M.avium_104                ---------MLTIGEVARRSGVAATTLRYYEQIGLLPAPTRLG-GQRRYD
                                                  :::     :  :::.*   **:    * . . * : 

MSMEG_1447|M.smegmatis_MC2_155      TDDVRRLMAIRRMKPLGFTLDEMGRLLD----------------------
Mvan_1160|M.vanbaalenii_PYR-1       DDDVSRLIAIRRMKPLGFTLDEMRGLLD----------------------
Mb3367|M.bovis_AF2122/97            PEIVDRLRFIHRGQAAGLALQEVRQILA----------------------
Rv3334|M.tuberculosis_H37Rv         PEIVDRLRFIHRGQAAGLALQEVRQILA----------------------
MMAR_0009|M.marinum_M               SADLTRLSQVIVYRRLELPLDEIARLLDEGNAVSHLVRQRERVMARLDEM
MUL_0011|M.ulcerans_Agy99           SADLTRLSQVIVYRRLELPLDEIARLLDEGNAVSHLVRQRERVMARLDEM
Mflv_0148|M.gilvum_PYR-GCK          SADLTRLSQIIVYRRLEMSLDEIASVLDEGDEISHLRRQRERVMSRLDEL
MAB_2309c|M.abscessus_ATCC_199      RHALRRISLIRVATGFGIPLSEVAEVLS----------------------
TH_0931|M.thermoresistible__bu      REMLRRVAFIRMSQRLGIPLARIREALA----------------------
MAV_3222|M.avium_104                EAVLSRLEVIALCKTAGFALDEIQRLFAD---------------------
                                       : *:  :       :.* .:   :                       

MSMEG_1447|M.smegmatis_MC2_155      -------------ALAVLDKPAATA---------AERATAAEVVSDC---
Mvan_1160|M.vanbaalenii_PYR-1       -------------ALDTLASPDTGA---------QARAEASAYLAVC---
Mb3367|M.bovis_AF2122/97            -------------IHDRGEAPCAHVRQLLSTRIDEVRAQIAELIALEGHL
Rv3334|M.tuberculosis_H37Rv         -------------IHDRGEAPCAHVRQLLSTRIDEVRAQIAELIALEGHL
MMAR_0009|M.marinum_M               KDLVEAIDQALEKAMTNTPMTDDDMRELFGDGFDDYRAETEQKWGETTEW
MUL_0011|M.ulcerans_Agy99           KDLVEAIDLALEKAMTNTPMTDDDMRELFGDGFDDYRVETEQKWGETAEW
Mflv_0148|M.gilvum_PYR-GCK          TELVGAIDQALENAMTNTPMTDDDMRELFGDSFDDYQAEAEQKWGETAEW
MAB_2309c|M.abscessus_ATCC_199      -------------TLPDYRAPSTRDWQRIS---RRWHAHLEARKNAIADM
TH_0931|M.thermoresistible__bu      -------------TLPSDRVPTSKDWAELS---AGWRADLDERILHLQRL
MAV_3222|M.avium_104                ---------------DAPGRPASRALAR------AKLAQIDAQLDSLTRA
                                                        .                .            

MSMEG_1447|M.smegmatis_MC2_155      ---HTRAQ-EACDRLTRHLAYARELTEQLAKVRG----------------
Mvan_1160|M.vanbaalenii_PYR-1       ---HGRAQ-EACVTLTRQLGYAREFMEQLAAASGEDVTPH----------
Mb3367|M.bovis_AF2122/97            QTLLDHAS-YGPPTEHDHSTVCWILESDLDEPTAIEVSDIHA--------
Rv3334|M.tuberculosis_H37Rv         QTLLDHAS-YGPPTEHDHSTVCWILESDLDEPTAIEVSDIHA--------
MMAR_0009|M.marinum_M               KESQRRTRSYGKDEWVRIKAEGQAVEKTLSDAFRAGLPADSEEAMNAAEQ
MUL_0011|M.ulcerans_Agy99           KESQRRTKSYGKDEWVRIKAEGQAIEKALSDAFRAGLPADSEEAMNAAEQ
Mflv_0148|M.gilvum_PYR-GCK          KESQRRATSYGKDDWVRIKAEGQAVEKALADAFRAGLPADSEEAMNAAEQ
MAB_2309c|M.abscessus_ATCC_199      QEKLTGCIGCGCLSMTKCALFNPADILADDGSTGALLLADLG--------
TH_0931|M.thermoresistible__bu      RDNLADCIGCGCLSLKTCALSNPDDALAARGPGAARL-------------
MAV_3222|M.avium_104                RAVIEWGMRCTCPSIDACTCGIHPTRPAPVGPDVRSARRF----------
                                                                                      

MSMEG_1447|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_1160|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb3367|M.bovis_AF2122/97            --------------------------------------------------
Rv3334|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_0009|M.marinum_M               HRRHVNRWFYDCPPAFHRSLGDMYVSDPRYIATYDESFGLPGLAAYCREA
MUL_0011|M.ulcerans_Agy99           HRRHVNRWFYDCPPAFHRNLGDMYVSDPRYIATYDESFGLPGLAAYCREA
Mflv_0148|M.gilvum_PYR-GCK          HRHHVNRWFYDCPPAFHRTLGDMYVSDPRYVATYDESFGLPGLARYCRDA
MAB_2309c|M.abscessus_ATCC_199      --------------------------------------------------
TH_0931|M.thermoresistible__bu      --------------------------------------------------
MAV_3222|M.avium_104                --------------------------------------------------
                                                                                      

MSMEG_1447|M.smegmatis_MC2_155      ----------
Mvan_1160|M.vanbaalenii_PYR-1       ----------
Mb3367|M.bovis_AF2122/97            ----------
Rv3334|M.tuberculosis_H37Rv         ----------
MMAR_0009|M.marinum_M               IHANANRTGG
MUL_0011|M.ulcerans_Agy99           IHANANRAGG
Mflv_0148|M.gilvum_PYR-GCK          IHANADRS--
MAB_2309c|M.abscessus_ATCC_199      ----------
TH_0931|M.thermoresistible__bu      ----------
MAV_3222|M.avium_104                ----------