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KLGSVFDSRNNALNACRLALATEVILFHSFPLTGRVVESKAILQLLFSVGVDGFFALSGFLITASWLRNP DVREYFVARALRILPGYYIVLAITAFVVAPLSVAIQGGSAARLLFSSAPVEYVLKNSALVQLQLDVGGTP HDIPYPGIWNASLWSLVFEVMCYIAVAGLGLLGLASRRWTAPVILILATIAAIMLPPLTFPGLWTIPQLA VRSAIMFSAGALLYQWRDRIPARWSLVAVSVVIVLFSGMLPDYRVLGALPLAYAVVVSGVLIKNKRMNIH TDLSYGVYIYASPTQQLLAVAGLYALNPFVFFGVSAVATLIPAAFSWFLIEKRALALKSRLKRKRATSAG TLGVEPAVADSVALRERALSPHEDS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4110c | - | - | 100% (376) | acetyltransferase AtfA |
| M. abscessus ATCC 19977 | MAB_4106c | - | e-111 | 57.59% (349) | acetyltransferase |
| M. abscessus ATCC 19977 | MAB_3448 | - | e-107 | 57.27% (344) | putative acetyltransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1286 | - | 1e-07 | 26.67% (195) | acyltransferase |
| M. gilvum PYR-GCK | Mflv_2226 | - | 1e-08 | 28.64% (206) | acyltransferase 3 |
| M. tuberculosis H37Rv | Rv1254 | - | 1e-07 | 26.67% (195) | acyltransferase |
| M. leprae Br4923 | MLBr_01101 | - | 6e-09 | 26.72% (262) | putative acyltransferase |
| M. marinum M | MMAR_4188 | - | 5e-10 | 24.90% (261) | integral membrane acyltransferase |
| M. avium 104 | MAV_4409 | - | 1e-133 | 64.12% (379) | putative acyltransferase |
| M. smegmatis MC2 155 | MSMEG_0390 | - | 1e-114 | 59.01% (344) | putative acyltransferase |
| M. thermoresistible (build 8) | TH_1720 | - | 1e-08 | 30.00% (210) | PROBABLE ACYLTRANSFERASE |
| M. ulcerans Agy99 | MUL_4492 | - | 4e-10 | 24.90% (261) | integral membrane acyltransferase |
| M. vanbaalenii PYR-1 | Mvan_4469 | - | 3e-10 | 29.90% (204) | acyltransferase 3 |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4188|M.marinum_M ----------MTLPEATDAQGGLEQISHVDRVASLTGIRAVAALLVVATH
MUL_4492|M.ulcerans_Agy99 ----------MTLPEATDAQGGLEQISHVDRVASLTGIRAVAALLVVTTH
MLBr_01101|M.leprae_Br4923 ----------MTLSEERDAQSGLKQVSHVDRVASLTGIRAVAALLIVGTH
Mb1286|M.bovis_AF2122/97 ----------MTLPKERAAQGGLERIAHVDRVASLTGIRAVAALLVVGTH
Rv1254|M.tuberculosis_H37Rv ----------MTLPKERAAQGGLERIAHVDRVASLTGIRAVAALLVVGTH
Mflv_2226|M.gilvum_PYR-GCK MISPNRAGRRSTAADDVDVAGGLESVS-TGRVASLTGIRAVAALLVVLTH
Mvan_4469|M.vanbaalenii_PYR-1 -MSLSDHADRPWFPDRTDLGGGLESVS-TGRVASLTGIRAVAALLVVLTH
TH_1720|M.thermoresistible__bu ---------VRPSPETDLDQGGLEQVSTVDRVAALTGVRAVAALSVMGTH
MAB_4110c|M.abscessus_ATCC_199 ----------MKLGSVFDS-----------RNNALNACRLALATEVILFH
MAV_4409|M.avium_104 ----------MKLGQVFDP-----------RRNALNALRLVLAAEVMLFH
MSMEG_0390|M.smegmatis_MC2_155 ------------MGKVFDP-----------RNNALNALRLLLAVGVILWH
. * :*.. * * :: *
MMAR_4188|M.marinum_M AAYTTGKYTHGYWGLVSARMEIGVPIFFVLSGFLLFRPWVHSAVTGAPPP
MUL_4492|M.ulcerans_Agy99 AAYTTGKYTHGYWGLVSARMEIGVPIFFVLSGFLLFRPWVHSAVTGAPPP
MLBr_01101|M.leprae_Br4923 AAYTTGKYTHGYWGLVGARLEIGVPIFFALSGFLLFSPWVKSAATGSPPP
Mb1286|M.bovis_AF2122/97 AAYTTGKYTHGYWGLMSSRMEIGVPIFFVLSGFLLFRPWVKSAATGGPPP
Rv1254|M.tuberculosis_H37Rv AAYTTGKYTHGYWGLMSSRMEIGVPIFFVLSGFLLFRPWVKSAATGGPPP
Mflv_2226|M.gilvum_PYR-GCK AAYTTGKYPQGYVGLVYSRMEIGVPIFFVLSGFLLFLPWVKAAAAGDAPP
Mvan_4469|M.vanbaalenii_PYR-1 AAYTTGKYPQGYVGLVYSRMEIGVPIFFVLSGFLLFLPWVSAAAAGGPPP
TH_1720|M.thermoresistible__bu AAYGTGTYNHGYVGLIFARMDIGVAVFFVLSGFLLFRPWVRAAADGTAAP
MAB_4110c|M.abscessus_ATCC_199 SFPLTGRVVESKA-ILQLLFSVGVDGFFALSGFLITASWLR-------NP
MAV_4409|M.avium_104 SWPITG-HMPPKS-ILQLFFSVGVDGFFAISGFLITRSWLS-------DP
MSMEG_0390|M.smegmatis_MC2_155 SWPLSGHGVTYKP-LEQLLEQVWVDGFFAISGFLITSSWLR-------NP
: :* : .: * **.:****: .*: *
MMAR_4188|M.marinum_M SLRRYTAHRVRRIMPAYVVVVLIAYVIYHYRIAGPNPGHSWLGLVRNLTL
MUL_4492|M.ulcerans_Agy99 SLRRYTAHRVRRIMPAYVVVVLIAYVIYHYRIAGPNPGHSWMGLVRNLTL
MLBr_01101|M.leprae_Br4923 SVSRYAWHRVRRIMPAYVITVLFAYALYHFRAAGPNPGHSWMGLVRNLTL
Mb1286|M.bovis_AF2122/97 SLSRYAWHRVRRIMPAYTVTVLLAYLVYHFRTAGPNPGHTWVGLFRNLTL
Rv1254|M.tuberculosis_H37Rv SLSRYAWHRVRRIMPAYTVTVLLAYLVYHFRTAGPNPGHTWVGLFRNLTL
Mflv_2226|M.gilvum_PYR-GCK SVGRYAWHRVRRIMPAYAVTVIAAYLVYHFRTAGPNPGHTWEGLFRNLTL
Mvan_4469|M.vanbaalenii_PYR-1 SVRRYAWHRVRRIMPAYVVTVVAAYLVYHFRTAGPNPGHTWEGLFRNLTL
TH_1720|M.thermoresistible__bu SVRRYARNRVRRIMPAYVVTVLAAYGIYAVRELEPNPGHTWVGLLRNLTL
MAB_4110c|M.abscessus_ATCC_199 DVREYFVARALRILPGYYIVLAITAFVVAPLSVAIQGGSAARLLFSSAPV
MAV_4409|M.avium_104 RLRDYLTARALRILPGFYICLIVTAFVFAPLSVVIQGGSPAKLLGSAAPL
MSMEG_0390|M.smegmatis_MC2_155 RLRDYATARVLRIFPGLWVCLLIIAFVMAPIGVLLQGGSVSGLMSSYAPI
: * *. **:*. : : : : * : .:
MMAR_4188|M.marinum_M TQIYTDGYLGSYLHQG-------------LTQMWSLAVEASFYVLLPFLA
MUL_4492|M.ulcerans_Agy99 TQIYTDGYLGSYLHQG-------------LTQMWSLAVEASFYVLLPFLA
MLBr_01101|M.leprae_Br4923 TQIYTDGYLGSYLHQG-------------LTQMWSLAVEVAFYVALPLLA
Mb1286|M.bovis_AF2122/97 TQIYTDGYLGAFLHQG-------------LTQMWSLAVEVAFYLALPALA
Rv1254|M.tuberculosis_H37Rv TQIYTDGYLGAFLHQG-------------LTQMWSLAVEVAFYLALPALA
Mflv_2226|M.gilvum_PYR-GCK TQIYTDDYLFSFLHQG-------------LTQMWSLAVEVAFYVVLPALA
Mvan_4469|M.vanbaalenii_PYR-1 TQIYTDNYLYSFLHQG-------------LTQMWSLAVEVAFYVALPVLA
TH_1720|M.thermoresistible__bu TQIYSDDYLTAYAHQG-------------LTQMWSLAVEVAFYAALPVLA
MAB_4110c|M.abscessus_ATCC_199 EYVLKNSALVQLQLDVGGTPHDIPYPGIWNASLWSLVFEVMCYIAVAGLG
MAV_4409|M.avium_104 EYVLKNSAIVYLQPSIDGTLHGVPGGNAWNGSMWSLIWELLCYLVVAAIG
MSMEG_0390|M.smegmatis_MC2_155 EYVLNNAVLNVYYAGINGTPQGIPWPGVWNGSLWTLVFEMICYIAVAVLG
: .: : .:*:* * * :. :.
MMAR_4188|M.marinum_M YLLLVVISRRRWQP--KLVVGALLAMATITPGWLVLIHTVSLFPDGARLW
MUL_4492|M.ulcerans_Agy99 YLLLVVISRRRWQP--KLVVGALLAMATITPGWLVLIHTVSLFPDGARLW
MLBr_01101|M.leprae_Br4923 YLLLVLLCQRRWQP--RLVLVVLAGMLLISPGWLILVHPDHWFPDGARLW
Mb1286|M.bovis_AF2122/97 YLLLVLVCRRRWQP--RLLLATMAGLTMISPAWLILVHNTHWMPDGARLW
Rv1254|M.tuberculosis_H37Rv YLLLVLVCRRRWQP--RLLLATMAGLTMISPAWLILVHNTHWMPDGARLW
Mflv_2226|M.gilvum_PYR-GCK YLLLVVLCRRRWRP--ALLMAGLTALAAVSPAWLWLVHSTDFLPDGAKLW
Mvan_4469|M.vanbaalenii_PYR-1 YLLLVVLCRRRWRP--GLLLAGLAVLAAVSPAWMWLVHNTTFLPDGAKLW
TH_1720|M.thermoresistible__bu WLLLVVLARRRWRP--VPLLTGLGVLAVVSPLWVVVLHRTDWLPLGAGFW
MAB_4110c|M.abscessus_ATCC_199 ---LLGLASRRWTAPVILILATIAAIMLPPLTFPGLWTIPQLAVRSAIMF
MAV_4409|M.avium_104 ---VVGLGNRRWISPLILVLATLGALVVPPLTFPGVWTIPQLAVRSAIMF
MSMEG_0390|M.smegmatis_MC2_155 ---IVGLLKRRWVIPAIFVLTLCATAYFSYPVFA-MQTIPQMVARFAVMF
:: : *** :: : : * ::
MMAR_4188|M.marinum_M LPSYLAWFLGGMLLTVLQAMKVQCYALAALPLATICYFIVATPIAGAPTT
MUL_4492|M.ulcerans_Agy99 LPSYLAWFLGGMLLTVLQAMKVQCYALAALPLATICYFIVATPIAGAPTT
MLBr_01101|M.leprae_Br4923 LPTYLAWFLGGMILAVLQVMGVRCYAFGAIPLAIICYFIVSTPIAGAPTT
Mb1286|M.bovis_AF2122/97 LPTYLAWFVGGMMLAVLAAMGVRCYAFVAIPLAVICYFIVSTPIAGAPTT
Rv1254|M.tuberculosis_H37Rv LPTYLAWFVGGMMLAVLAAMGVRCYAFVAIPLAVICYFIVSTPIAGAPTT
Mflv_2226|M.gilvum_PYR-GCK LPGYLVWFIGGMMLAALQPTGFRAYALACVPLAVVSYVIVSTPIAGEPTT
Mvan_4469|M.vanbaalenii_PYR-1 LPGYLAWFVGGMVLAALRPLGVRAYALACVPLALVSYFIVSTPIAGEPTT
TH_1720|M.thermoresistible__bu LPHYLIWFVGGMVLAVLQAQGVRAYAAATVPVAVAAYLIVATPIAGDTGA
MAB_4110c|M.abscessus_ATCC_199 SAGALLYQWRDRIPARWSLVAVSVVIVLFSGMLPDYRVLGALPLAYAVVV
MAV_4409|M.avium_104 SAGAVMYQWRDVIPARWSLVAVALAIVAAAGFLPDYRVVGALPLAYAVIV
MSMEG_0390|M.smegmatis_MC2_155 AAGALIHQYRDVIPARWSLVGIAVVLVLASGFLSNYRVIGALPLAYAVIV
. : . : : . . .: : *:* .
MMAR_4188|M.marinum_M SPSALT--------EAVVKACFYTVIATLAVAPLALG--------DQGWY
MUL_4492|M.ulcerans_Agy99 SPSALT--------EAVVKACFYTVIATLAVAPLALG--------DQGWY
MLBr_01101|M.leprae_Br4923 SPASLG--------EALIKVGFYAAIATLAVAPLTLG--------DLGWY
Mb1286|M.bovis_AF2122/97 SPTALA--------EALVKTAFYAVIAVLAVAPLALG--------DQGWY
Rv1254|M.tuberculosis_H37Rv SPTALA--------EALVKTAFYAVIAVLAVAPLALG--------DQGWY
Mflv_2226|M.gilvum_PYR-GCK SPAELR--------EALVKTAFYAVIATLVVAPLALGGRPGADGRESGLY
Mvan_4469|M.vanbaalenii_PYR-1 SPAELR--------EALAKTAFYAVIATLVVAPLALG--------DTGLY
TH_1720|M.thermoresistible__bu PVLNLG--------QDLAKVMFYAVIATLVVAPPALG--------NRGWY
MAB_4110c|M.abscessus_ATCC_199 SGVLIKNKRMNIHTDLSYGVYIYASPTQQLLAVAGLYA-------LNPFV
MAV_4409|M.avium_104 TGSLLKSERLVLRTDLSYGVYIYAFPTQQLLAVCGLATR------LHPAL
MSMEG_0390|M.smegmatis_MC2_155 AGALLRNRRLNLRNDLSYGVYIYAFPVQQLLAILGFAN-------SQPFL
. : : . :*: . :* :
MMAR_4188|M.marinum_M SQLLASRPMVWLGEISYEIFLVHLVTMEFAMVYVVRYRVYTGSMLNLFIA
MUL_4492|M.ulcerans_Agy99 SQLLASRPMVWLGEISYEIFLVHLVTMEFAMVYVVRYWVYTGSMLNLFIA
MLBr_01101|M.leprae_Br4923 SWLLSSRPMVWLGEISYEIFLIHLVTMEFAMVYVVQDHVYTGSMLNLIVA
Mb1286|M.bovis_AF2122/97 AQLLASRPMVFLGEISYEIFLIHLVTMEIAMVDVLGYRVYTSSMVNLCLV
Rv1254|M.tuberculosis_H37Rv AQLLASRPMVFLGEISYEIFLIHLVTMEIAMVDVLGYRVYTSSMVNLCLV
Mflv_2226|M.gilvum_PYR-GCK ARMLSSRPMVFLGEISYEIFLIHLVTMELVMVEIVRYPIYTGSVWALFFG
Mvan_4469|M.vanbaalenii_PYR-1 SRFMASRPMVFLGEISYEIFLIHLVTMELVMVEILRSPVYTGSVWQLFFG
TH_1720|M.thermoresistible__bu TRMLGSRPMVWLGEISYEIFLVHVIVMEIAMVSVLRWPVYTGSVLGLFAT
MAB_4110c|M.abscessus_ATCC_199 FFGVSAVATLIPAAFSWFLIEKRALALKSRLKRK----RATSAG--TLGV
MAV_4409|M.avium_104 FFLASVAATLPLAAASWFLIEKPSMALKRRLKRKWTGPRAAESDPRVSQA
MSMEG_0390|M.smegmatis_MC2_155 FFVIATAATVPLAALSWFLVEKRAIALKSRLKRR----------------
. . : . *: :. :.:: :
MMAR_4188|M.marinum_M TMVITIPLAWVLHRFTR--VRSE------------
MUL_4492|M.ulcerans_Agy99 TMVITIPLAWVLHRFTR--VRSE------------
MLBr_01101|M.leprae_Br4923 TLVLTIPLAWLLHRCTR--MRS-------------
Mb1286|M.bovis_AF2122/97 TLVLTIPLAWLLHRFTR--VQGDRPS---------
Rv1254|M.tuberculosis_H37Rv TLVLTIPLAWLLHRFTR--VQGDRPS---------
Mflv_2226|M.gilvum_PYR-GCK TLLMTIPLASLLHRFTR--VRT-------------
Mvan_4469|M.vanbaalenii_PYR-1 TLVVTIPPAWLLHRFTR--VRS-------------
TH_1720|M.thermoresistible__bu TLALTIPVAWLLHRFTRPPIRPAVPARSADRTDRR
MAB_4110c|M.abscessus_ATCC_199 EPAVADSVALRERALSP---HEDS-----------
MAV_4409|M.avium_104 EPAPADVLADRPAPEAP---GHF------------
MSMEG_0390|M.smegmatis_MC2_155 ---RTDTVADTTQKVSD---RGAG-----------
: * :