For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
SLSDHADRPWFPDRTDLGGGLESVSTGRVASLTGIRAVAALLVVLTHAAYTTGKYPQGYVGLVYSRMEIG VPIFFVLSGFLLFLPWVSAAAAGGPPPSVRRYAWHRVRRIMPAYVVTVVAAYLVYHFRTAGPNPGHTWEG LFRNLTLTQIYTDNYLYSFLHQGLTQMWSLAVEVAFYVALPVLAYLLLVVLCRRRWRPGLLLAGLAVLAA VSPAWMWLVHNTTFLPDGAKLWLPGYLAWFVGGMVLAALRPLGVRAYALACVPLALVSYFIVSTPIAGEP TTSPAELREALAKTAFYAVIATLVVAPLALGDTGLYSRFMASRPMVFLGEISYEIFLIHLVTMELVMVEI LRSPVYTGSVWQLFFGTLVVTIPPAWLLHRFTRVRS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4469 | - | - | 100% (387) | acyltransferase 3 |
| M. vanbaalenii PYR-1 | Mvan_4285 | - | e-115 | 58.43% (356) | acyltransferase 3 |
| M. vanbaalenii PYR-1 | Mvan_0251 | - | 8e-44 | 38.48% (330) | acyltransferase 3 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1286 | - | 1e-162 | 76.36% (368) | acyltransferase |
| M. gilvum PYR-GCK | Mflv_2226 | - | 0.0 | 86.13% (382) | acyltransferase 3 |
| M. tuberculosis H37Rv | Rv1254 | - | 1e-162 | 76.36% (368) | acyltransferase |
| M. leprae Br4923 | MLBr_01101 | - | 1e-154 | 70.93% (375) | putative acyltransferase |
| M. abscessus ATCC 19977 | MAB_1404 | - | 1e-134 | 63.76% (367) | acyltransferase |
| M. marinum M | MMAR_4188 | - | 1e-153 | 69.41% (376) | integral membrane acyltransferase |
| M. avium 104 | MAV_1402 | - | 1e-153 | 71.39% (374) | putative acyltransferase, putative |
| M. smegmatis MC2 155 | MSMEG_5041 | - | 1e-172 | 80.81% (370) | acyltransferase |
| M. thermoresistible (build 8) | TH_2230 | - | 1e-175 | 81.25% (368) | PROBABLE ACYLTRANSFERASE |
| M. ulcerans Agy99 | MUL_4492 | - | 1e-153 | 69.41% (376) | integral membrane acyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_4469|M.vanbaalenii_PYR-1 -MSLSDHADRPWFPDRTDLGGGLESVST-GRVASLTGIRAVAALLVVLTH
Mflv_2226|M.gilvum_PYR-GCK MISPNRAGRRSTAADDVDVAGGLESVST-GRVASLTGIRAVAALLVVLTH
MSMEG_5041|M.smegmatis_MC2_155 -MTLSGSVQDP-------AQGGLESVGAPERVGSLTGIRALAALLVVLTH
TH_2230|M.thermoresistible__bu -MTVRRGGELT---EPDVVQGGLESISRAERVASLTGIRAVAALLVVLTH
MLBr_01101|M.leprae_Br4923 -MTLSEE---------RDAQSGLKQVSHVDRVASLTGIRAVAALLIVGTH
MAV_1402|M.avium_104 -MTLSEE---------QDAQGGLEQTSRVDRVASLTGVRAVAALLVVGTH
MMAR_4188|M.marinum_M -MTLPEA---------TDAQGGLEQISHVDRVASLTGIRAVAALLVVATH
MUL_4492|M.ulcerans_Agy99 -MTLPEA---------TDAQGGLEQISHVDRVASLTGIRAVAALLVVTTH
Mb1286|M.bovis_AF2122/97 -MTLPKE---------RAAQGGLERIAHVDRVASLTGIRAVAALLVVGTH
Rv1254|M.tuberculosis_H37Rv -MTLPKE---------RAAQGGLERIAHVDRVASLTGIRAVAALLVVGTH
MAB_1404|M.abscessus_ATCC_1997 -MTAVSP------------TESAPVVRASGRVAALTGVRAVAATLVVATH
:: . **.:***:**:** *:* **
Mvan_4469|M.vanbaalenii_PYR-1 AAYTTGKYPQG-------YVGLVYSRMEIGVPIFFVLSGFLLFLPWVSAA
Mflv_2226|M.gilvum_PYR-GCK AAYTTGKYPQG-------YVGLVYSRMEIGVPIFFVLSGFLLFLPWVKAA
MSMEG_5041|M.smegmatis_MC2_155 AAYTTGKYPQG-------YLGLVWSRAEIGVPIFFVLSGFLLFRPWVKAA
TH_2230|M.thermoresistible__bu AAYTTGRYPQG-------YLGLVYSRMEIGVPIFFVLSGFLLFGPWVRAA
MLBr_01101|M.leprae_Br4923 AAYTTGKYTHG-------YWGLVGARLEIGVPIFFALSGFLLFSPWVKSA
MAV_1402|M.avium_104 AAYTTGKYTHG-------YWGLVGSRMEIGVPIFFVLSGYLLFRPWVKSA
MMAR_4188|M.marinum_M AAYTTGKYTHG-------YWGLVSARMEIGVPIFFVLSGFLLFRPWVHSA
MUL_4492|M.ulcerans_Agy99 AAYTTGKYTHG-------YWGLVSARMEIGVPIFFVLSGFLLFRPWVHSA
Mb1286|M.bovis_AF2122/97 AAYTTGKYTHG-------YWGLMSSRMEIGVPIFFVLSGFLLFRPWVKSA
Rv1254|M.tuberculosis_H37Rv AAYTTGKYTHG-------YWGLMSSRMEIGVPIFFVLSGFLLFRPWVKSA
MAB_1404|M.abscessus_ATCC_1997 AAYSTGNYVVDGVSPWKAYLHLLQSRLEIGVPIFFVLSGFLLFLPWVRAA
***:**.* . * *: :* ********.***:*** *** :*
Mvan_4469|M.vanbaalenii_PYR-1 AAGGPPPSVRRYAWHRVRRIMPAYVVTVVAAYLVYHFRTAGPNPGHTWEG
Mflv_2226|M.gilvum_PYR-GCK AAGDAPPSVGRYAWHRVRRIMPAYAVTVIAAYLVYHFRTAGPNPGHTWEG
MSMEG_5041|M.smegmatis_MC2_155 ATGAPAPSVRRYAWHRVRRIMPAYVVTVLIAYLVYHFRTAGPNPGHTWEG
TH_2230|M.thermoresistible__bu AERRPAPSVKRYAWRRVRRIMPAYVVTVLAAYAVYHFRDAGPNPGHTWEG
MLBr_01101|M.leprae_Br4923 ATGSPPPSVSRYAWHRVRRIMPAYVITVLFAYALYHFRAAGPNPGHSWMG
MAV_1402|M.avium_104 ATGGPPPSLSRYVWHRVRRIMPPYVITVLFAYVLYHFREAGPNPGHSWLG
MMAR_4188|M.marinum_M VTGAPPPSLRRYTAHRVRRIMPAYVVVVLIAYVIYHYRIAGPNPGHSWLG
MUL_4492|M.ulcerans_Agy99 VTGAPPPSLRRYTAHRVRRIMPAYVVVVLIAYVIYHYRIAGPNPGHSWMG
Mb1286|M.bovis_AF2122/97 ATGGPPPSLSRYAWHRVRRIMPAYTVTVLLAYLVYHFRTAGPNPGHTWVG
Rv1254|M.tuberculosis_H37Rv ATGGPPPSLSRYAWHRVRRIMPAYTVTVLLAYLVYHFRTAGPNPGHTWVG
MAB_1404|M.abscessus_ATCC_1997 ADNTASPSVKRYAWHRFRRIMPAYWILVAIAYIWYHIRDQYPNPGHTWLG
. ..**: **. :*.*****.* : * ** ** * *****:* *
Mvan_4469|M.vanbaalenii_PYR-1 LFRNLTLTQIYTDNYLYSFLHQGLTQMWSLAVEVAFYVALPVLAYLLLVV
Mflv_2226|M.gilvum_PYR-GCK LFRNLTLTQIYTDDYLFSFLHQGLTQMWSLAVEVAFYVVLPALAYLLLVV
MSMEG_5041|M.smegmatis_MC2_155 LFRNLTLTQIYADNYLYSFLHQGLTQMWSLAVEAAFYVVLPLLAYVLLVL
TH_2230|M.thermoresistible__bu LLRNLTHTQIYTDNYLYSYLHQGLTQMWSLAVEVAFYAVLPLLAYLLLVV
MLBr_01101|M.leprae_Br4923 LVRNLTLTQIYTDGYLGSYLHQGLTQMWSLAVEVAFYVALPLLAYLLLVL
MAV_1402|M.avium_104 LARNLTLTQIYCNGYLGKYLHQGLTQMWSLAVEASFYVILPLLAYLLLVL
MMAR_4188|M.marinum_M LVRNLTLTQIYTDGYLGSYLHQGLTQMWSLAVEASFYVLLPFLAYLLLVV
MUL_4492|M.ulcerans_Agy99 LVRNLTLTQIYTDGYLGSYLHQGLTQMWSLAVEASFYVLLPFLAYLLLVV
Mb1286|M.bovis_AF2122/97 LFRNLTLTQIYTDGYLGAFLHQGLTQMWSLAVEVAFYLALPALAYLLLVL
Rv1254|M.tuberculosis_H37Rv LFRNLTLTQIYTDGYLGAFLHQGLTQMWSLAVEVAFYLALPALAYLLLVL
MAB_1404|M.abscessus_ATCC_1997 LFRNLTLTQIYTSNYGYRYIHQGMTQIWSLAVEAAFYVALPFLAWLLVKK
* **** **** ..* ::***:**:******.:** ** **::*:
Mvan_4469|M.vanbaalenii_PYR-1 LCRRRWRPGLLLAGLAVLAAVSPAWMWLVHNT-TFLPDGAKLWLPGYLAW
Mflv_2226|M.gilvum_PYR-GCK LCRRRWRPALLMAGLTALAAVSPAWLWLVHST-DFLPDGAKLWLPGYLVW
MSMEG_5041|M.smegmatis_MC2_155 LCRRRWRPGLLMTGLVVAAAVSPVWLVIVHHHGADLPDGARLWLPTYLAW
TH_2230|M.thermoresistible__bu VCRRRWRPGLLLTGLAVLAAISPAWLYLVHTV-DWLPDGARLWLPTYLIW
MLBr_01101|M.leprae_Br4923 LCQRRWQPRLVLVVLAGMLLISPGWLILVHPD-HWFPDGARLWLPTYLAW
MAV_1402|M.avium_104 VCRRQWQPKLVLGALAGLALVSPAWLVLVHTD-HWFPDGARLWLPTYLAW
MMAR_4188|M.marinum_M ISRRRWQPKLVVGALLAMATITPGWLVLIHTV-SLFPDGARLWLPSYLAW
MUL_4492|M.ulcerans_Agy99 ISRRRWQPKLVVGALLAMATITPGWLVLIHTV-SLFPDGARLWLPSYLAW
Mb1286|M.bovis_AF2122/97 VCRRRWQPRLLLATMAGLTMISPAWLILVHNT-HWMPDGARLWLPTYLAW
Rv1254|M.tuberculosis_H37Rv VCRRRWQPRLLLATMAGLTMISPAWLILVHNT-HWMPDGARLWLPTYLAW
MAB_1404|M.abscessus_ATCC_1997 LCGGQWRPARLLVGLGGLALVTPLWMSLVYTI-GAFPDGAKLWLPAYLSW
:. :*:* :: : ::* *: ::: :****:**** ** *
Mvan_4469|M.vanbaalenii_PYR-1 FVGGMVLAALRPLGVRAYALACVPLALVSYFIVSTPIAGEPTTSPAELRE
Mflv_2226|M.gilvum_PYR-GCK FIGGMMLAALQPTGFRAYALACVPLAVVSYVIVSTPIAGEPTTSPAELRE
MSMEG_5041|M.smegmatis_MC2_155 FVAGMMLAVLGQLKVRGYAMVCVPLALVCYFIASTPIAGEPTTSPAKLSE
TH_2230|M.thermoresistible__bu FLGGMMLAALQPMGVRAYALVCIPLALICYFIVATPIGGEPTTSPNELWE
MLBr_01101|M.leprae_Br4923 FLGGMILAVLQVMGVRCYAFGAIPLAIICYFIVSTPIAGAPTTSPASLGE
MAV_1402|M.avium_104 FLAGMMLTVLQEMGARAYGFVAIPLAVVSYFIVSTPIAGAPTTSPATLSE
MMAR_4188|M.marinum_M FLGGMLLTVLQAMKVQCYALAALPLATICYFIVATPIAGAPTTSPSALTE
MUL_4492|M.ulcerans_Agy99 FLGGMLLTVLQAMKVQCYALAALPLATICYFIVATPIAGAPTTSPSALTE
Mb1286|M.bovis_AF2122/97 FVGGMMLAVLAAMGVRCYAFVAIPLAVICYFIVSTPIAGAPTTSPTALAE
Rv1254|M.tuberculosis_H37Rv FVGGMMLAVLAAMGVRCYAFVAIPLAVICYFIVSTPIAGAPTTSPTALAE
MAB_1404|M.abscessus_ATCC_1997 FVGGMILSVLAVMGVRCYALVTVPLAVICYLIVSTRIAGDPTTSPWALPQ
*:.**:*:.* : *.: :*** :.*.*.:* *.* ***** * :
Mvan_4469|M.vanbaalenii_PYR-1 ALAKTAFYAVIATLVVAPLALG--------DTGLYSRFMASRPMVFLGEI
Mflv_2226|M.gilvum_PYR-GCK ALVKTAFYAVIATLVVAPLALGGRPGADGRESGLYARMLSSRPMVFLGEI
MSMEG_5041|M.smegmatis_MC2_155 ALFKTAFYAVIAALLVAPPALG--------DRGWYTRFLASRPMVFLGEI
TH_2230|M.thermoresistible__bu AWAKTGFYTVIATLMVAPLALG--------NKGWYSRVLGSRPMVFLGEI
MLBr_01101|M.leprae_Br4923 ALIKVGFYAAIATLAVAPLTLG--------DLGWYSWLLSSRPMVWLGEI
MAV_1402|M.avium_104 ALFKACFYAVIAALAVAPLALG--------DHGWYSRLLASRPMVWLGEI
MMAR_4188|M.marinum_M AVVKACFYTVIATLAVAPLALG--------DQGWYSQLLASRPMVWLGEI
MUL_4492|M.ulcerans_Agy99 AVVKACFYTVIATLAVAPLALG--------DQGWYSQLLASRPMVWLGEI
Mb1286|M.bovis_AF2122/97 ALVKTAFYAVIAVLAVAPLALG--------DQGWYAQLLASRPMVFLGEI
Rv1254|M.tuberculosis_H37Rv ALVKTAFYAVIAVLAVAPLALG--------DQGWYAQLLASRPMVFLGEI
MAB_1404|M.abscessus_ATCC_1997 ALTKSIFYVVIATLLVAPAALG--------DNGWYVRFLSTRPMVWLGEI
* * **..**.* *** :** : * * .:.:****:****
Mvan_4469|M.vanbaalenii_PYR-1 SYEIFLIHLVTMELVMVEILRSPVYTGSVWQLFFGTLVVTIPPAWLLHR-
Mflv_2226|M.gilvum_PYR-GCK SYEIFLIHLVTMELVMVEIVRYPIYTGSVWALFFGTLLMTIPLASLLHR-
MSMEG_5041|M.smegmatis_MC2_155 SYEIFLIHLIIMELVMVEILQSPVYTGSMFNLFVLTMAFTIPASWLLHR-
TH_2230|M.thermoresistible__bu SYEIFLIHLILMEVAMVEILRSPVYTGSMFWLFVWTMVLTIPLAWLLHR-
MLBr_01101|M.leprae_Br4923 SYEIFLIHLVTMEFAMVYVVQDHVYTGSMLNLIVATLVLTIPLAWLLHR-
MAV_1402|M.avium_104 SYEIFLIHLITMEFAMDYIVGARVYTGSMLNLFVATLVLTIPLAWLLHR-
MMAR_4188|M.marinum_M SYEIFLVHLVTMEFAMVYVVRYRVYTGSMLNLFIATMVITIPLAWVLHR-
MUL_4492|M.ulcerans_Agy99 SYEIFLVHLVTMEFAMVYVVRYWVYTGSMLNLFIATMVITIPLAWVLHR-
Mb1286|M.bovis_AF2122/97 SYEIFLIHLVTMEIAMVDVLGYRVYTSSMVNLCLVTLVLTIPLAWLLHR-
Rv1254|M.tuberculosis_H37Rv SYEIFLIHLVTMEIAMVDVLGYRVYTSSMVNLCLVTLVLTIPLAWLLHR-
MAB_1404|M.abscessus_ATCC_1997 SYELFLIHMILMEIVMVDLLHYHVYTGSVVIVFLVTMLVSVPASWLIHRT
***:**:*:: **..* :: :**.*: : . *: .::* : ::**
Mvan_4469|M.vanbaalenii_PYR-1 -------FTRVRS-------
Mflv_2226|M.gilvum_PYR-GCK -------FTRVRT-------
MSMEG_5041|M.smegmatis_MC2_155 -------FTRVRS-------
TH_2230|M.thermoresistible__bu -------FTRVRDQ------
MLBr_01101|M.leprae_Br4923 -------CTRMRS-------
MAV_1402|M.avium_104 -------FTRVRD-------
MMAR_4188|M.marinum_M -------FTRVRSE------
MUL_4492|M.ulcerans_Agy99 -------FTRVRSE------
Mb1286|M.bovis_AF2122/97 -------FTRVQGDRPS---
Rv1254|M.tuberculosis_H37Rv -------FTRVQGDRPS---
MAB_1404|M.abscessus_ATCC_1997 VEVILARSSRLRKSLAQRMR
:*::