For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
TLPEATDAQGGLEQISHVDRVASLTGIRAVAALLVVATHAAYTTGKYTHGYWGLVSARMEIGVPIFFVLS GFLLFRPWVHSAVTGAPPPSLRRYTAHRVRRIMPAYVVVVLIAYVIYHYRIAGPNPGHSWLGLVRNLTLT QIYTDGYLGSYLHQGLTQMWSLAVEASFYVLLPFLAYLLLVVISRRRWQPKLVVGALLAMATITPGWLVL IHTVSLFPDGARLWLPSYLAWFLGGMLLTVLQAMKVQCYALAALPLATICYFIVATPIAGAPTTSPSALT EAVVKACFYTVIATLAVAPLALGDQGWYSQLLASRPMVWLGEISYEIFLVHLVTMEFAMVYVVRYRVYTG SMLNLFIATMVITIPLAWVLHRFTRVRSE*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_4188 | - | - | 100% (380) | integral membrane acyltransferase |
| M. marinum M | MMAR_0477 | - | 7e-43 | 35.23% (352) | integral membrane acyltransferase |
| M. marinum M | MMAR_0312 | - | 6e-13 | 26.05% (380) | transmembrane acyltransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1286 | - | 1e-176 | 75.79% (380) | acyltransferase |
| M. gilvum PYR-GCK | Mflv_2226 | - | 1e-147 | 66.06% (386) | acyltransferase 3 |
| M. tuberculosis H37Rv | Rv1254 | - | 1e-176 | 75.79% (380) | acyltransferase |
| M. leprae Br4923 | MLBr_01101 | - | 1e-178 | 77.57% (379) | putative acyltransferase |
| M. abscessus ATCC 19977 | MAB_1404 | - | 1e-128 | 59.07% (364) | acyltransferase |
| M. avium 104 | MAV_1402 | - | 1e-180 | 78.84% (378) | putative acyltransferase, putative |
| M. smegmatis MC2 155 | MSMEG_5041 | - | 1e-152 | 68.82% (372) | acyltransferase |
| M. thermoresistible (build 8) | TH_2230 | - | 1e-155 | 70.63% (378) | PROBABLE ACYLTRANSFERASE |
| M. ulcerans Agy99 | MUL_4492 | - | 0.0 | 99.21% (380) | integral membrane acyltransferase |
| M. vanbaalenii PYR-1 | Mvan_4469 | - | 1e-153 | 69.41% (376) | acyltransferase 3 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2226|M.gilvum_PYR-GCK MISPNRAGRRSTAADDVDVAGGLESVST-GRVASLTGIRAVAALLVVLTH
Mvan_4469|M.vanbaalenii_PYR-1 -MSLSDHADRPWFPDRTDLGGGLESVST-GRVASLTGIRAVAALLVVLTH
MSMEG_5041|M.smegmatis_MC2_155 -MTLSGSVQDP-------AQGGLESVGAPERVGSLTGIRALAALLVVLTH
TH_2230|M.thermoresistible__bu -MTVRRGGELT---EPDVVQGGLESISRAERVASLTGIRAVAALLVVLTH
Mb1286|M.bovis_AF2122/97 -MTLPKE---------RAAQGGLERIAHVDRVASLTGIRAVAALLVVGTH
Rv1254|M.tuberculosis_H37Rv -MTLPKE---------RAAQGGLERIAHVDRVASLTGIRAVAALLVVGTH
MMAR_4188|M.marinum_M -MTLPEA---------TDAQGGLEQISHVDRVASLTGIRAVAALLVVATH
MUL_4492|M.ulcerans_Agy99 -MTLPEA---------TDAQGGLEQISHVDRVASLTGIRAVAALLVVTTH
MLBr_01101|M.leprae_Br4923 -MTLSEE---------RDAQSGLKQVSHVDRVASLTGIRAVAALLIVGTH
MAV_1402|M.avium_104 -MTLSEE---------QDAQGGLEQTSRVDRVASLTGVRAVAALLVVGTH
MAB_1404|M.abscessus_ATCC_1997 -MTAVSP------------TESAPVVRASGRVAALTGVRAVAATLVVATH
:: . **.:***:**:** *:* **
Mflv_2226|M.gilvum_PYR-GCK AAYTTGKYPQG-------YVGLVYSRMEIGVPIFFVLSGFLLFLPWVKAA
Mvan_4469|M.vanbaalenii_PYR-1 AAYTTGKYPQG-------YVGLVYSRMEIGVPIFFVLSGFLLFLPWVSAA
MSMEG_5041|M.smegmatis_MC2_155 AAYTTGKYPQG-------YLGLVWSRAEIGVPIFFVLSGFLLFRPWVKAA
TH_2230|M.thermoresistible__bu AAYTTGRYPQG-------YLGLVYSRMEIGVPIFFVLSGFLLFGPWVRAA
Mb1286|M.bovis_AF2122/97 AAYTTGKYTHG-------YWGLMSSRMEIGVPIFFVLSGFLLFRPWVKSA
Rv1254|M.tuberculosis_H37Rv AAYTTGKYTHG-------YWGLMSSRMEIGVPIFFVLSGFLLFRPWVKSA
MMAR_4188|M.marinum_M AAYTTGKYTHG-------YWGLVSARMEIGVPIFFVLSGFLLFRPWVHSA
MUL_4492|M.ulcerans_Agy99 AAYTTGKYTHG-------YWGLVSARMEIGVPIFFVLSGFLLFRPWVHSA
MLBr_01101|M.leprae_Br4923 AAYTTGKYTHG-------YWGLVGARLEIGVPIFFALSGFLLFSPWVKSA
MAV_1402|M.avium_104 AAYTTGKYTHG-------YWGLVGSRMEIGVPIFFVLSGYLLFRPWVKSA
MAB_1404|M.abscessus_ATCC_1997 AAYSTGNYVVDGVSPWKAYLHLLQSRLEIGVPIFFVLSGFLLFLPWVRAA
***:**.* . * *: :* ********.***:*** *** :*
Mflv_2226|M.gilvum_PYR-GCK AAGDAPPSVGRYAWHRVRRIMPAYAVTVIAAYLVYHFRTAGPNPGHTWEG
Mvan_4469|M.vanbaalenii_PYR-1 AAGGPPPSVRRYAWHRVRRIMPAYVVTVVAAYLVYHFRTAGPNPGHTWEG
MSMEG_5041|M.smegmatis_MC2_155 ATGAPAPSVRRYAWHRVRRIMPAYVVTVLIAYLVYHFRTAGPNPGHTWEG
TH_2230|M.thermoresistible__bu AERRPAPSVKRYAWRRVRRIMPAYVVTVLAAYAVYHFRDAGPNPGHTWEG
Mb1286|M.bovis_AF2122/97 ATGGPPPSLSRYAWHRVRRIMPAYTVTVLLAYLVYHFRTAGPNPGHTWVG
Rv1254|M.tuberculosis_H37Rv ATGGPPPSLSRYAWHRVRRIMPAYTVTVLLAYLVYHFRTAGPNPGHTWVG
MMAR_4188|M.marinum_M VTGAPPPSLRRYTAHRVRRIMPAYVVVVLIAYVIYHYRIAGPNPGHSWLG
MUL_4492|M.ulcerans_Agy99 VTGAPPPSLRRYTAHRVRRIMPAYVVVVLIAYVIYHYRIAGPNPGHSWMG
MLBr_01101|M.leprae_Br4923 ATGSPPPSVSRYAWHRVRRIMPAYVITVLFAYALYHFRAAGPNPGHSWMG
MAV_1402|M.avium_104 ATGGPPPSLSRYVWHRVRRIMPPYVITVLFAYVLYHFREAGPNPGHSWLG
MAB_1404|M.abscessus_ATCC_1997 ADNTASPSVKRYAWHRFRRIMPAYWILVAIAYIWYHIRDQYPNPGHTWLG
. ..**: **. :*.*****.* : * ** ** * *****:* *
Mflv_2226|M.gilvum_PYR-GCK LFRNLTLTQIYTDDYLFSFLHQGLTQMWSLAVEVAFYVVLPALAYLLLVV
Mvan_4469|M.vanbaalenii_PYR-1 LFRNLTLTQIYTDNYLYSFLHQGLTQMWSLAVEVAFYVALPVLAYLLLVV
MSMEG_5041|M.smegmatis_MC2_155 LFRNLTLTQIYADNYLYSFLHQGLTQMWSLAVEAAFYVVLPLLAYVLLVL
TH_2230|M.thermoresistible__bu LLRNLTHTQIYTDNYLYSYLHQGLTQMWSLAVEVAFYAVLPLLAYLLLVV
Mb1286|M.bovis_AF2122/97 LFRNLTLTQIYTDGYLGAFLHQGLTQMWSLAVEVAFYLALPALAYLLLVL
Rv1254|M.tuberculosis_H37Rv LFRNLTLTQIYTDGYLGAFLHQGLTQMWSLAVEVAFYLALPALAYLLLVL
MMAR_4188|M.marinum_M LVRNLTLTQIYTDGYLGSYLHQGLTQMWSLAVEASFYVLLPFLAYLLLVV
MUL_4492|M.ulcerans_Agy99 LVRNLTLTQIYTDGYLGSYLHQGLTQMWSLAVEASFYVLLPFLAYLLLVV
MLBr_01101|M.leprae_Br4923 LVRNLTLTQIYTDGYLGSYLHQGLTQMWSLAVEVAFYVALPLLAYLLLVL
MAV_1402|M.avium_104 LARNLTLTQIYCNGYLGKYLHQGLTQMWSLAVEASFYVILPLLAYLLLVL
MAB_1404|M.abscessus_ATCC_1997 LFRNLTLTQIYTSNYGYRYIHQGMTQIWSLAVEAAFYVALPFLAWLLVKK
* **** **** ..* ::***:**:******.:** ** **::*:
Mflv_2226|M.gilvum_PYR-GCK LCRRRWRPALLMAGLTALAAVSPAWLWLVHST-DFLPDGAKLWLPGYLVW
Mvan_4469|M.vanbaalenii_PYR-1 LCRRRWRPGLLLAGLAVLAAVSPAWMWLVHNT-TFLPDGAKLWLPGYLAW
MSMEG_5041|M.smegmatis_MC2_155 LCRRRWRPGLLMTGLVVAAAVSPVWLVIVHHHGADLPDGARLWLPTYLAW
TH_2230|M.thermoresistible__bu VCRRRWRPGLLLTGLAVLAAISPAWLYLVHTV-DWLPDGARLWLPTYLIW
Mb1286|M.bovis_AF2122/97 VCRRRWQPRLLLATMAGLTMISPAWLILVHNT-HWMPDGARLWLPTYLAW
Rv1254|M.tuberculosis_H37Rv VCRRRWQPRLLLATMAGLTMISPAWLILVHNT-HWMPDGARLWLPTYLAW
MMAR_4188|M.marinum_M ISRRRWQPKLVVGALLAMATITPGWLVLIHTV-SLFPDGARLWLPSYLAW
MUL_4492|M.ulcerans_Agy99 ISRRRWQPKLVVGALLAMATITPGWLVLIHTV-SLFPDGARLWLPSYLAW
MLBr_01101|M.leprae_Br4923 LCQRRWQPRLVLVVLAGMLLISPGWLILVHPD-HWFPDGARLWLPTYLAW
MAV_1402|M.avium_104 VCRRQWQPKLVLGALAGLALVSPAWLVLVHTD-HWFPDGARLWLPTYLAW
MAB_1404|M.abscessus_ATCC_1997 LCGGQWRPARLLVGLGGLALVTPLWMSLVYTI-GAFPDGAKLWLPAYLSW
:. :*:* :: : ::* *: ::: :****:**** ** *
Mflv_2226|M.gilvum_PYR-GCK FIGGMMLAALQPTGFRAYALACVPLAVVSYVIVSTPIAGEPTTSPAELRE
Mvan_4469|M.vanbaalenii_PYR-1 FVGGMVLAALRPLGVRAYALACVPLALVSYFIVSTPIAGEPTTSPAELRE
MSMEG_5041|M.smegmatis_MC2_155 FVAGMMLAVLGQLKVRGYAMVCVPLALVCYFIASTPIAGEPTTSPAKLSE
TH_2230|M.thermoresistible__bu FLGGMMLAALQPMGVRAYALVCIPLALICYFIVATPIGGEPTTSPNELWE
Mb1286|M.bovis_AF2122/97 FVGGMMLAVLAAMGVRCYAFVAIPLAVICYFIVSTPIAGAPTTSPTALAE
Rv1254|M.tuberculosis_H37Rv FVGGMMLAVLAAMGVRCYAFVAIPLAVICYFIVSTPIAGAPTTSPTALAE
MMAR_4188|M.marinum_M FLGGMLLTVLQAMKVQCYALAALPLATICYFIVATPIAGAPTTSPSALTE
MUL_4492|M.ulcerans_Agy99 FLGGMLLTVLQAMKVQCYALAALPLATICYFIVATPIAGAPTTSPSALTE
MLBr_01101|M.leprae_Br4923 FLGGMILAVLQVMGVRCYAFGAIPLAIICYFIVSTPIAGAPTTSPASLGE
MAV_1402|M.avium_104 FLAGMMLTVLQEMGARAYGFVAIPLAVVSYFIVSTPIAGAPTTSPATLSE
MAB_1404|M.abscessus_ATCC_1997 FVGGMILSVLAVMGVRCYALVTVPLAVICYLIVSTRIAGDPTTSPWALPQ
*:.**:*:.* : *.: :*** :.*.*.:* *.* ***** * :
Mflv_2226|M.gilvum_PYR-GCK ALVKTAFYAVIATLVVAPLALGGRPGADGRESGLYARMLSSRPMVFLGEI
Mvan_4469|M.vanbaalenii_PYR-1 ALAKTAFYAVIATLVVAPLALG--------DTGLYSRFMASRPMVFLGEI
MSMEG_5041|M.smegmatis_MC2_155 ALFKTAFYAVIAALLVAPPALG--------DRGWYTRFLASRPMVFLGEI
TH_2230|M.thermoresistible__bu AWAKTGFYTVIATLMVAPLALG--------NKGWYSRVLGSRPMVFLGEI
Mb1286|M.bovis_AF2122/97 ALVKTAFYAVIAVLAVAPLALG--------DQGWYAQLLASRPMVFLGEI
Rv1254|M.tuberculosis_H37Rv ALVKTAFYAVIAVLAVAPLALG--------DQGWYAQLLASRPMVFLGEI
MMAR_4188|M.marinum_M AVVKACFYTVIATLAVAPLALG--------DQGWYSQLLASRPMVWLGEI
MUL_4492|M.ulcerans_Agy99 AVVKACFYTVIATLAVAPLALG--------DQGWYSQLLASRPMVWLGEI
MLBr_01101|M.leprae_Br4923 ALIKVGFYAAIATLAVAPLTLG--------DLGWYSWLLSSRPMVWLGEI
MAV_1402|M.avium_104 ALFKACFYAVIAALAVAPLALG--------DHGWYSRLLASRPMVWLGEI
MAB_1404|M.abscessus_ATCC_1997 ALTKSIFYVVIATLLVAPAALG--------DNGWYVRFLSTRPMVWLGEI
* * **..**.* *** :** : * * .:.:****:****
Mflv_2226|M.gilvum_PYR-GCK SYEIFLIHLVTMELVMVEIVRYPIYTGSVWALFFGTLLMTIPLASLLHR-
Mvan_4469|M.vanbaalenii_PYR-1 SYEIFLIHLVTMELVMVEILRSPVYTGSVWQLFFGTLVVTIPPAWLLHR-
MSMEG_5041|M.smegmatis_MC2_155 SYEIFLIHLIIMELVMVEILQSPVYTGSMFNLFVLTMAFTIPASWLLHR-
TH_2230|M.thermoresistible__bu SYEIFLIHLILMEVAMVEILRSPVYTGSMFWLFVWTMVLTIPLAWLLHR-
Mb1286|M.bovis_AF2122/97 SYEIFLIHLVTMEIAMVDVLGYRVYTSSMVNLCLVTLVLTIPLAWLLHR-
Rv1254|M.tuberculosis_H37Rv SYEIFLIHLVTMEIAMVDVLGYRVYTSSMVNLCLVTLVLTIPLAWLLHR-
MMAR_4188|M.marinum_M SYEIFLVHLVTMEFAMVYVVRYRVYTGSMLNLFIATMVITIPLAWVLHR-
MUL_4492|M.ulcerans_Agy99 SYEIFLVHLVTMEFAMVYVVRYWVYTGSMLNLFIATMVITIPLAWVLHR-
MLBr_01101|M.leprae_Br4923 SYEIFLIHLVTMEFAMVYVVQDHVYTGSMLNLIVATLVLTIPLAWLLHR-
MAV_1402|M.avium_104 SYEIFLIHLITMEFAMDYIVGARVYTGSMLNLFVATLVLTIPLAWLLHR-
MAB_1404|M.abscessus_ATCC_1997 SYELFLIHMILMEIVMVDLLHYHVYTGSVVIVFLVTMLVSVPASWLIHRT
***:**:*:: **..* :: :**.*: : . *: .::* : ::**
Mflv_2226|M.gilvum_PYR-GCK -------FTRVRT-------
Mvan_4469|M.vanbaalenii_PYR-1 -------FTRVRS-------
MSMEG_5041|M.smegmatis_MC2_155 -------FTRVRS-------
TH_2230|M.thermoresistible__bu -------FTRVRDQ------
Mb1286|M.bovis_AF2122/97 -------FTRVQGDRPS---
Rv1254|M.tuberculosis_H37Rv -------FTRVQGDRPS---
MMAR_4188|M.marinum_M -------FTRVRSE------
MUL_4492|M.ulcerans_Agy99 -------FTRVRSE------
MLBr_01101|M.leprae_Br4923 -------CTRMRS-------
MAV_1402|M.avium_104 -------FTRVRD-------
MAB_1404|M.abscessus_ATCC_1997 VEVILARSSRLRKSLAQRMR
:*::