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VLGRVFDPRNNALNAWRLVLATSVILWHTWPLTGHEIPPRPITQLLSQVGVDGFFAVSGFLITSSWMRNP QPRSYFTSRALRILPGLWVCVFITAFVIAPLGVLIQRGSVSELMKSGAPAAYVLNNGLMNVLFYPGIAGT PKNIPWPGVWNGSLWTLAFETGCYIVVALLGISSLLKHRWTIPTAFVLTLTATAVFGFPAFAMSTIPQMI ARFAVMFAAGALIYQYQDKIPAKWSLVALSLGLLLLSGLLPNYRVLGAIPLAYLVIASGALLKRLNLRND LSYGVYIYAFPIQQLLVIMGLATLRVFPFFIVATLVTLPLAAMSWFVVEKRALALKKRLRVKAGAG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_3448 | - | - | 100% (346) | putative acetyltransferase |
| M. abscessus ATCC 19977 | MAB_1725c | - | e-158 | 78.13% (343) | putative acetyltransferase |
| M. abscessus ATCC 19977 | MAB_4106c | - | e-134 | 66.47% (343) | acetyltransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0530 | - | 9e-06 | 24.78% (347) | membrane acyltransferase |
| M. gilvum PYR-GCK | Mflv_1859 | - | 3e-07 | 25.00% (348) | acyltransferase 3 |
| M. tuberculosis H37Rv | Rv0517 | - | 9e-06 | 24.78% (347) | membrane acyltransferase |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_0857 | - | 3e-06 | 25.70% (323) | transmembrane acyltransferase |
| M. avium 104 | MAV_3274 | - | 1e-115 | 59.71% (345) | putative acyltransferase |
| M. smegmatis MC2 155 | MSMEG_0390 | - | 1e-138 | 69.50% (341) | putative acyltransferase |
| M. thermoresistible (build 8) | TH_4330 | - | 1e-05 | 23.64% (368) | PUTATIVE acyltransferase 3 |
| M. ulcerans Agy99 | MUL_0609 | - | 6e-07 | 25.70% (323) | transmembrane acyltransferase |
| M. vanbaalenii PYR-1 | Mvan_4875 | - | 8e-09 | 25.29% (348) | acyltransferase 3 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0530|M.bovis_AF2122/97 -----------------------------------MAGGMDQPPGQPRRR
Rv0517|M.tuberculosis_H37Rv -----------------------------------MAGGMDQPPGQPRRR
Mflv_1859|M.gilvum_PYR-GCK --MTAVSAAPIRVGPRRYVGPGQSIPALDGVRAIAVALVLADHGGVPGLS
Mvan_4875|M.vanbaalenii_PYR-1 --MTAVSAAPIRVGPRRYVGPGQAIPALDGVRAIAVALVLADHGGVPGLS
MMAR_0857|M.marinum_M MTIRQDRSASQLRAAQRPGPRIAFRPDIEGLRAIAVVAVVLYHAGIPGIS
MUL_0609|M.ulcerans_Agy99 ---------------------------------------MSCHAGIPGIS
MAB_3448|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0390|M.smegmatis_MC2_155 --------------------------------------------------
MAV_3274|M.avium_104 ---------------------------------------MSADPNVSDPT
TH_4330|M.thermoresistible__bu ----------------------------MPGTLVAMAVTAEQVAGNPGDS
Mb0530|M.bovis_AF2122/97 TRQQSSDGKNGVRAAEITGEIRALTG-------LRIVAAVWVVLFHFRPM
Rv0517|M.tuberculosis_H37Rv TRQQSSDGKNGVRAAEITGEIRALTG-------LRIVAAVWVVLFHFRPM
Mflv_1859|M.gilvum_PYR-GCK GGFLGVDVFFVLSGFLITSLLLDEIGRTGRVGLKGFWIRRARRLLPALVV
Mvan_4875|M.vanbaalenii_PYR-1 GGFLGVDVFFVLSGFLITSLLLDEVGRTGRIGLKGFWIRRARRLLPALLV
MMAR_0857|M.marinum_M GGYIGVDVFFVISGFLITGLLWSEVTTTNTVALGRFYGARARRLLPAAAT
MUL_0609|M.ulcerans_Agy99 GGYIGVDVFFVISGFLITGLLWREVTTTNTVALGRFYGARARRLLPAAAT
MAB_3448|M.abscessus_ATCC_1997 ---------------MLGRVFDPRNN----------ALNAWRLVLATSVI
MSMEG_0390|M.smegmatis_MC2_155 ----------------MGKVFDPRNN----------ALNALRLLLAVGVI
MAV_3274|M.avium_104 TIAARGPARRRVPGPTLAQVFDTRIN----------ALNVWRLVLASGVI
TH_4330|M.thermoresistible__bu SGASPRDLSHEVSG--TRSFLPAVEG--------------LRACAALGVI
:
Mb0530|M.bovis_AF2122/97 LGDASPGFRDALAPVLDCG---AQGVDLFFILSGFVLTWNYLDRMGRSWS
Rv0517|M.tuberculosis_H37Rv LGDASPGFRDALAPVLDCG---AQGVDLFFILSGFVLTWNYLDRMGRSWS
Mflv_1859|M.gilvum_PYR-GCK MVLAVVAVRGLFSDESVAN-LRDDAVATFFWMSNWIFVAQDTDYFSQGAP
Mvan_4875|M.vanbaalenii_PYR-1 MVLAVVALRELFSEESTAN-LREDAVAAFFWMSNWVFVAQHTDYFSQGAP
MMAR_0857|M.marinum_M VGVATAIVSAIVLPPLQARRVFVDGIASALYVGNYRFAVQGTDYMASDLP
MUL_0609|M.ulcerans_Agy99 VGVATAIVSAIVLPPLQARRVFVDGIASALYVGNYRFAVQGTDYMASDLP
MAB_3448|M.abscessus_ATCC_1997 LWHTWPLTGHEIPPRPITQLLSQVGVDGFFAVSGFLITSS----WMRNPQ
MSMEG_0390|M.smegmatis_MC2_155 LWHSWPLSGHGVTYKPLEQLLEQVWVDGFFAISGFLITSS----WLRNPR
MAV_3274|M.avium_104 LQHSWPLTGRKVHP-PYDQLFPQVWVDGFFAISGFLIAAS----WVRNPR
TH_4330|M.thermoresistible__bu VTHVAFQTGHTSGAVGRLLGRFDLAVAVFFALSGFLLWRGHAAAVRGLRP
: : : :..: :
Mb0530|M.bovis_AF2122/97 VRA---NLHFLWLRLARVWPVYLVTLHLAAVWVIFTLHVGH---------
Rv0517|M.tuberculosis_H37Rv VRA---NLHFLWLRLARVWPVYLVTLHLAAVWVIFTLHVGH---------
Mflv_1859|M.gilvum_PYR-GCK PSP---LQHTWSLAVEEQYYVLWPLLIAAVIAGLTALAYRRG-MTLSQRA
Mvan_4875|M.vanbaalenii_PYR-1 PSP---LQHTWSLAVEEQFYVLWPLLIAAVLAGLAALAYRRG-VPLSQRV
MMAR_0857|M.marinum_M PSP---FQHYWSLGVEEQFYLVWPALIIATAWLLRRIGKNN------RGA
MUL_0609|M.ulcerans_Agy99 PSP---FQHYWSLGVEDQFYLVWPALIIATAWLLRRIGKNN------RGA
MAB_3448|M.abscessus_ATCC_1997 PRS---YFTSRALRILPGLWVCVFITAFVIAPLGVLIQRGS---------
MSMEG_0390|M.smegmatis_MC2_155 LRD---YATARVLRIFPGLWVCLLIIAFVMAPIGVLLQGGS---------
MAV_3274|M.avium_104 LRE---YVAARALRILPGLWVCLVVIAFVIAPIGVAIQGGS---------
TH_4330|M.thermoresistible__bu TPATGRYLRSRVVRIMPGYLVAVVVILLLLPGATADLTVWLANLTLTQIY
: : : :
Mb0530|M.bovis_AF2122/97 VPSPEAGQLTAISYVRQILLVQLWFQP-----YFDGSS------------
Rv0517|M.tuberculosis_H37Rv VPSPEAGQLTAISYVRQILLVQLWFQP-----YFDGSS------------
Mflv_1859|M.gilvum_PYR-GCK VRTAVFLLATAGIVASATATALMSSDGNLNRVYFGTDTRVQALLVGAAAA
Mvan_4875|M.vanbaalenii_PYR-1 VRTAVFVLAAGGVVASATATFFLSSDATLNRVYFGTDTRVQALLVGAAAA
MMAR_0857|M.marinum_M TPYAVVLVLVAAASLAAAAIWTRTSPP---WAFFSLPTRAWELAVGG-LV
MUL_0609|M.ulcerans_Agy99 TPYAVVLVLVAAASLAAAAIWTRTSPP---WAFFSLPTRAWELAVGG-LV
MAB_3448|M.abscessus_ATCC_1997 VSELMKSGAPAAYVLNNGLMNVLFYPG-----------------------
MSMEG_0390|M.smegmatis_MC2_155 VSGLMSSYAPIEYVLNNAVLN-VYYAG-----------------------
MAV_3274|M.avium_104 AAKLLMSRAPIEYVLHNAVLH-VFFAG-----------------------
TH_4330|M.thermoresistible__bu VPLTLTSGLTQMWSLSVEMTFYLVLPL-----------------------
.
Mb0530|M.bovis_AF2122/97 ------WDGPAWS-----------ISAEWLAYLLFGLLILVIFRMKHATR
Rv0517|M.tuberculosis_H37Rv ------WDGPAWS-----------ISAEWLAYLLFGLLILVIFRMKHATR
Mflv_1859|M.gilvum_PYR-GCK ALLVRDWRGLTAGLEIFRSRWARWVAWSLPVVGLVVLFLAARIATGSVEE
Mvan_4875|M.vanbaalenii_PYR-1 ALVVRDWRGLTAGLVIFRSRWARWVAWSLPAVGLVVLFSAARMATGSAAE
MMAR_0857|M.marinum_M ALTMQQWRRLPL------------VPATIVGWGGLALLLLTCTQLGPNTP
MUL_0609|M.ulcerans_Agy99 ALTMQQWRRLPL------------VPATIVGWGGLALLLLTCTQLGPNTP
MAB_3448|M.abscessus_ATCC_1997 ------IAGTPKN-----------IPWPGVWNGSLWTLAFETGCYIVVAL
MSMEG_0390|M.smegmatis_MC2_155 ------INGTPQG-----------IPWPGVWNGSLWTLVFEMICYIAVAV
MAV_3274|M.avium_104 ------IDGTPRH-----------VPFPGVWDGVLWTLIFEIFCYIAIAV
TH_4330|M.thermoresistible__bu --LALLARQVPVR-----------ARIPVLLATAVLSLFWVRIPFGPDSG
. . :
Mb0530|M.bovis_AF2122/97 ARG----LMWLAFAASLPPVVLLLASG------QFYTPWSWLPRIVTQFA
Rv0517|M.tuberculosis_H37Rv ARG----LMWLAFAASLPPVVLLLASG------QFYTPWSWLPRIVTQFA
Mflv_1859|M.gilvum_PYR-GCK FRSG--LLIVVALAAVLVIAPVALAQDGPVARLLSVWPLVGLGAISYGVY
Mvan_4875|M.vanbaalenii_PYR-1 FRSG--LLIVVALAAVLVIAPVALAQDGPVARLLSAGPLVGLGAISYGVY
MMAR_0857|M.marinum_M YPGT--AALLPVLGTALVIGSGCVTGSMGVGRVLCRPVMRAIGRVSYSWY
MUL_0609|M.ulcerans_Agy99 YPGT--AALLPVLGTALVIGSGCVTGAMGVGRVLCRPVMRAIGRVSYSWY
MAB_3448|M.abscessus_ATCC_1997 LGIS--SLLKHRWTIPTAFVLTLTATAVFGFPAFAMSTIPQMIARFAVMF
MSMEG_0390|M.smegmatis_MC2_155 LGIV--GLLKRRWVIPAIFVLTLCATAYFSYPVFAMQTIPQMVARFAVMF
MAV_3274|M.avium_104 AGVA--GLLKRRWPAVVVFILLVVFSALVAYP-VEVQTVFQMIGRFALVF
TH_4330|M.thermoresistible__bu LNPWNWPPAFFSWFAAGMILAELTVTRVGWFHRLARRRVLMGMFALAAFL
Mb0530|M.bovis_AF2122/97 AGALACAAVRRLRPTDRARRIAGYLSVLVGVAIVGILYLLHAHP------
Rv0517|M.tuberculosis_H37Rv AGALACAAVRRLRPTDRARRIAGYLSVLVGVAIVGILYLLHAHP------
Mflv_1859|M.gilvum_PYR-GCK LWHWPIFLILNGERTGASGWQLFALRCAATIAVAAVSWWLIEQP---VRE
Mvan_4875|M.vanbaalenii_PYR-1 LWHWPIFLVLNGERTGIEGWELFALRCAATVAVAAVSWWLIEQP---IRE
MMAR_0857|M.marinum_M LWHWPVLLLLPPLLGDPAGLPARLAATTVSAGLAVITMYLVENPGRFTAA
MUL_0609|M.ulcerans_Agy99 LWHWPVLLLLPPLLGDPAGLPARLAATTVSAGLAVITMYLVENPGRFTAA
MAB_3448|M.abscessus_ATCC_1997 AAGALIYQYQDKIPAKWSLVALSLGLLLLSG-LLPNYRVLGAIP------
MSMEG_0390|M.smegmatis_MC2_155 AAGALIHQYRDVIPARWSLVGIAVVLVLASG-FLSNYRVIGALP------
MAV_3274|M.avium_104 AAGTLLHQFQDKIPARWSLVALSAVIVLAAGLLMPNYRVLAAIP------
TH_4330|M.thermoresistible__bu VAASPLVGLEGLAPGSIVQVTLKTVMGALLAAALLAPLVLDRPD------
:
Mb0530|M.bovis_AF2122/97 -----------LAGVEDSGGVVDVLFVPLVISLAIG--------------
Rv0517|M.tuberculosis_H37Rv -----------LAGVEDSGGVVDVLFVPLVISLAIG--------------
Mflv_1859|M.gilvum_PYR-GCK WRPAFVPMLPLAGATAATAAVLTMTVLPVRVVPPTPEPGPLVDIAALVGP
Mvan_4875|M.vanbaalenii_PYR-1 WRPAFVPMLPLAAATAATAAVVTMTVLPVRMVPATPEPGPEVDIAALVGA
MMAR_0857|M.marinum_M LRSVRASLTLAAAATAAAACACALLLTAIPVPVGHGTAAPEAKIIALPPA
MUL_0609|M.ulcerans_Agy99 LRSVRASLTLAAAATAAAACACALLLTAIPVPVGHGTAASEAKIIALPPA
MAB_3448|M.abscessus_ATCC_1997 ----------LAYLVIASGALLK--RLNLRNDLSYG--------------
MSMEG_0390|M.smegmatis_MC2_155 ----------LAYAVIVAGALLRNRRLNLRNDLSYG--------------
MAV_3274|M.avium_104 ----------LAYAVVVSGALIHHERLRLRTDLSYG--------------
TH_4330|M.thermoresistible__bu ----------------TPHRFLASAPMVTLGRWSYG--------------
.
Mb0530|M.bovis_AF2122/97 -----------VGSLPALLSTRLMVFGGQ---------------------
Rv0517|M.tuberculosis_H37Rv -----------VGSLPALLSTRLMVFGGQ---------------------
Mflv_1859|M.gilvum_PYR-GCK EVPVEVTR---APTPRAPGDLRVAVFGDS----IAWTMMRYLPDTPG---
Mvan_4875|M.vanbaalenii_PYR-1 EVPVEVTR---APRPSAPGDLRVAVFGDS----IAWTLMRYLPETPG---
MMAR_0857|M.marinum_M ALPQRALSPQEAAVQQAFAAVRAAVAASAGLGAVPSNLNPPLAAAPGDKA
MUL_0609|M.ulcerans_Agy99 ALPQRALSPQEAAVQQAFAAVRAAVAASAGLGAVPSTLNPPLAAAPGDKA
MAB_3448|M.abscessus_ATCC_1997 -----------VYIYAFPIQQLLVIMGLAT--------------------
MSMEG_0390|M.smegmatis_MC2_155 -----------VYIYAFPVQQLLAILGFAN--------------------
MAV_3274|M.avium_104 -----------VYIYAWPMQQLLAICGLSF--------------------
TH_4330|M.thermoresistible__bu -------------IFVWHLAALAMVFPMIG--------------------
:
Mb0530|M.bovis_AF2122/97 --------ISFCLYMVHELVHTAWG--------------WAVQQYELALQ
Rv0517|M.tuberculosis_H37Rv --------ISFCLYMVHELVHTAWG--------------WAVQQYELALQ
Mflv_1859|M.gilvum_PYR-GCK --------VDFADFTTIGCGIARGGPYEYVG-----------QELQQKPE
Mvan_4875|M.vanbaalenii_PYR-1 --------LDFADYTTIGCGIARGGPYEYVG-----------QELPQKPE
MMAR_0857|M.marinum_M AVFVNGCLRSWRDLGQSECATADTASPTTVALVGDSHAAMWDPALQLVAE
MUL_0609|M.ulcerans_Agy99 AVFVNGCLRSWRDLAQSECATADTASPTTVALVGDSHAAMWDPALQLVAE
MAB_3448|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0390|M.smegmatis_MC2_155 --------------------------------------------------
MAV_3274|M.avium_104 --------------------------------------------------
TH_4330|M.thermoresistible__bu --------------------------------------------------
Mb0530|M.bovis_AF2122/97 DQPWKWNVVGLLAIALGAAILLYHFVE-----------------------
Rv0517|M.tuberculosis_H37Rv DQPWKWNVVGLLAIALGAAILLYHFVE-----------------------
Mflv_1859|M.gilvum_PYR-GCK CDEWPARWAQRIGHQKPDVVLL--MVG---------RWEVVDRMSEGR--
Mvan_4875|M.vanbaalenii_PYR-1 CDEWPARWAQRVGHEKPDVVLL--MVG---------RWEVVDRMMEGQ--
MMAR_0857|M.marinum_M QRHWRLETLAKVTCPMQDLPILSPYLGREYTECEQWRGEIMGRLQSERPR
MUL_0609|M.ulcerans_Agy99 QRHWRLETLAKVTCPMQDLPILSPYLGREYTECEQWRGEIMGRLQSERPR
MAB_3448|M.abscessus_ATCC_1997 LRVFPFFIVATLVTLP----------------------------------
MSMEG_0390|M.smegmatis_MC2_155 SQPFLFFVIATAATVP----------------------------------
MAV_3274|M.avium_104 LPPVVFAVVAVVVTLP----------------------------------
TH_4330|M.thermoresistible__bu --EFPFNGNMPVVLVLTVLFTIA---------------------------
Mb0530|M.bovis_AF2122/97 --------------------------------------------------
Rv0517|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_1859|M.gilvum_PYR-GCK ----------WTHIGEPGYDAYLRSELNRALDILGSTGARLVVA------
Mvan_4875|M.vanbaalenii_PYR-1 ----------WTHIGEAGYDAYLRGELNRALDILGSTGARVVVT------
MMAR_0857|M.marinum_M LVVLSMSRRYQPDFSFASYDPAWIDTLNRTVAQLRRNGSSVLVLGPVADP
MUL_0609|M.ulcerans_Agy99 LVVLSMSRRYQPDFSFASYDPAWIDTLNRTVAQLRRNGSSVLVLGPVADP
MAB_3448|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0390|M.smegmatis_MC2_155 --------------------------------------------------
MAV_3274|M.avium_104 --------------------------------------------------
TH_4330|M.thermoresistible__bu --------------------------------------------------
Mb0530|M.bovis_AF2122/97 ---EPDRRWMRRMVDVKAASARSEPGEPVGSTRYQIDDALEGVSARAV--
Rv0517|M.tuberculosis_H37Rv ---EPGRRWMRRMVDVKAASARSEPGEPVGSTRYQIDDALEGVSARAV--
Mflv_1859|M.gilvum_PYR-GCK --TEPYNRRAEKADGSLYPEDQPDRVERWNTMLREVVDERPNATVLDLNE
Mvan_4875|M.vanbaalenii_PYR-1 --TEPYNRRAEKPDGSLYPEDQPKRVETWNALLRSVVDKRPNATVLDLNK
MMAR_0857|M.marinum_M QSSVPTCLSAHLDDAGACAPSRSAATNAGGVAAEQTATEAGGGHYADLTD
MUL_0609|M.ulcerans_Agy99 QSSVPTCLSAHLDDAGACAPSRSAATNAGGVAAEQTATEAGGGHYADLTD
MAB_3448|M.abscessus_ATCC_1997 ---LAAMSWFVVEKRALALKKRLR--------------VKAGAG------
MSMEG_0390|M.smegmatis_MC2_155 ---LAALSWFLVEKRAIALKSRLKRRRTDTVADTTQKVSDRGAG------
MAV_3274|M.avium_104 ---LAALSWFLVEKRALSLKSRIKRRARGWGAVVSSGSRISTPGS-----
TH_4330|M.thermoresistible__bu ---IAAVSYGLVEQPCRAAYRRWEMRRARPDAPAPPLDSAVTSVATPISR
. :
Mb0530|M.bovis_AF2122/97 -----------------------------------------------
Rv0517|M.tuberculosis_H37Rv -----------------------------------------------
Mflv_1859|M.gilvum_PYR-GCK KLSPNGYYQMRVNGLKVRSDGVHPTPEAVEWMTPWLVEAIRTP----
Mvan_4875|M.vanbaalenii_PYR-1 KLSPNGYYQTRVDGIRVRSDGVHPTPEAVEWLTPWLVDALKPE----
MMAR_0857|M.marinum_M LFCTPDRCPTIIGNTLVFRDDNHLTTEYAQLLAPVIGALADRALAAG
MUL_0609|M.ulcerans_Agy99 LFCTPDRCPTIIGNTLVFRDDNHLTTEYAQLLAPVIGALADRALAAG
MAB_3448|M.abscessus_ATCC_1997 -----------------------------------------------
MSMEG_0390|M.smegmatis_MC2_155 -----------------------------------------------
MAV_3274|M.avium_104 -----------------------------------------------
TH_4330|M.thermoresistible__bu -----------------------------------------------