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LGKVFDPRNNALNALRLLLAVGVILWHSWPLSGHGVTYKPLEQLLEQVWVDGFFAISGFLITSSWLRNPR LRDYATARVLRIFPGLWVCLLIIAFVMAPIGVLLQGGSVSGLMSSYAPIEYVLNNAVLNVYYAGINGTPQ GIPWPGVWNGSLWTLVFEMICYIAVAVLGIVGLLKRRWVIPAIFVLTLCATAYFSYPVFAMQTIPQMVAR FAVMFAAGALIHQYRDVIPARWSLVGIAVVLVLASGFLSNYRVIGALPLAYAVIVAGALLRNRRLNLRND LSYGVYIYAFPVQQLLAILGFANSQPFLFFVIATAATVPLAALSWFLVEKRAIALKSRLKRRRTDTVADT TQKVSDRGAG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0390 | - | - | 100% (360) | putative acyltransferase |
| M. smegmatis MC2 155 | MSMEG_3429 | - | e-109 | 57.27% (344) | O-acyl transferase |
| M. smegmatis MC2 155 | MSMEG_5041 | - | 1e-06 | 21.77% (372) | acyltransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0233 | - | 3e-08 | 27.34% (267) | integral membrane acyltransferase |
| M. gilvum PYR-GCK | Mflv_1859 | - | 2e-08 | 25.66% (343) | acyltransferase 3 |
| M. tuberculosis H37Rv | Rv0228 | - | 3e-08 | 27.34% (267) | integral membrane acyltransferase |
| M. leprae Br4923 | MLBr_01101 | - | 1e-06 | 27.37% (179) | putative acyltransferase |
| M. abscessus ATCC 19977 | MAB_4106c | - | 1e-155 | 72.42% (359) | acetyltransferase |
| M. marinum M | MMAR_4188 | - | 6e-07 | 27.41% (197) | integral membrane acyltransferase |
| M. avium 104 | MAV_3274 | - | 1e-128 | 64.14% (343) | putative acyltransferase |
| M. thermoresistible (build 8) | TH_2230 | - | 1e-06 | 21.32% (258) | PROBABLE ACYLTRANSFERASE |
| M. ulcerans Agy99 | MUL_4492 | - | 5e-07 | 27.41% (197) | integral membrane acyltransferase |
| M. vanbaalenii PYR-1 | Mvan_1670 | - | 6e-09 | 23.82% (361) | acyltransferase 3 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0233|M.bovis_AF2122/97 MGPADESGAPIRPQTPHRHTVLVTNGQVVGGTRGFLPAVEGMRACAAVGV
Rv0228|M.tuberculosis_H37Rv MGPADESGAPIRPQTPHRHTVLVTNGQVVGGTRGFLPAVEGMRACAAVGV
MMAR_4188|M.marinum_M --------MTLP------EATDAQGGLEQISHVDRVASLTGIRAVAALLV
MUL_4492|M.ulcerans_Agy99 --------MTLP------EATDAQGGLEQISHVDRVASLTGIRAVAALLV
MLBr_01101|M.leprae_Br4923 --------MTLS------EERDAQSGLKQVSHVDRVASLTGIRAVAALLI
TH_2230|M.thermoresistible__bu --------MTVRRGGELTEPDVVQGGLESISRAERVASLTGIRAVAALLV
MSMEG_0390|M.smegmatis_MC2_155 ---------------------------MGKVFDPRNNALNALRLLLAVGV
MAB_4106c|M.abscessus_ATCC_199 -------------MTKAGATGQAKGLTLGQVFDPRNNALNAWRLALAVSV
MAV_3274|M.avium_104 MSADPNVSDPTTIAARGPARRRVPGPTLAQVFDTRINALNVWRLVLASGV
Mflv_1859|M.gilvum_PYR-GCK -------------MTAVSAAPIRVGPRRYVGPGQSIPALDGVRAIAVALV
Mvan_1670|M.vanbaalenii_PYR-1 ----MLPGGDRMVTRVDRWREASGRRRRRAERANYRLDIQGLRAVAVLAV
: * . :
Mb0233|M.bovis_AF2122/97 VVTHVAFQTG-HSSGVGGRLFGRFDLAVAVFFAVSGFLLWRGHAAAARDL
Rv0228|M.tuberculosis_H37Rv VVTHVAFQTG-HSSGVGGRLFGRFDLAVAVFFAVSGFLLWRGHAAAARDL
MMAR_4188|M.marinum_M VATHAAYTTGKYTHGYWGLVSARMEIGVPIFFVLSGFLLFRPWVHSAVTG
MUL_4492|M.ulcerans_Agy99 VTTHAAYTTGKYTHGYWGLVSARMEIGVPIFFVLSGFLLFRPWVHSAVTG
MLBr_01101|M.leprae_Br4923 VGTHAAYTTGKYTHGYWGLVGARLEIGVPIFFALSGFLLFSPWVKSAATG
TH_2230|M.thermoresistible__bu VLTHAAYTTGRYPQGYLGLVYSRMEIGVPIFFVLSGFLLFGPWVRAAAER
MSMEG_0390|M.smegmatis_MC2_155 ILWHSWPLSGHGVTYKP-LEQLLEQVWVDGFFAISGFLITSSWLR-----
MAB_4106c|M.abscessus_ATCC_199 IFWHSWPLTGRTITYRP-FEQLIEQVGVDGFFAVSGFLITASWLR-----
MAV_3274|M.avium_104 ILQHSWPLTGR-KVHPP-YDQLFPQVWVDGFFAISGFLIAASWVR-----
Mflv_1859|M.gilvum_PYR-GCK LADHG---------GVPGLSGG--FLGVDVFFVLSGFLITSLLLDEIG-R
Mvan_1670|M.vanbaalenii_PYR-1 VAHHLWG------------IPPGGFVGIDVFFVITGYFVTENLLKASAEH
: * : : **.::*:::
Mb0233|M.bovis_AF2122/97 RSHPRTGPYLRSRVARIMP-AYVVAVVVILSLLPDADHAS-----LTVWL
Rv0228|M.tuberculosis_H37Rv RSHPRTGPYLRSRVARIMP-AYVVAVVVILSLLPDADHAS-----LTVWL
MMAR_4188|M.marinum_M APPPSLRRYTAHRVRRIMP-AYVVVVLIAYVIYHYRIAGPNPGHSWLGLV
MUL_4492|M.ulcerans_Agy99 APPPSLRRYTAHRVRRIMP-AYVVVVLIAYVIYHYRIAGPNPGHSWMGLV
MLBr_01101|M.leprae_Br4923 SPPPSVSRYAWHRVRRIMP-AYVITVLFAYALYHFRAAGPNPGHSWMGLV
TH_2230|M.thermoresistible__bu RPAPSVKRYAWRRVRRIMP-AYVVTVLAAYAVYHFRDAGPNPGHTWEGLL
MSMEG_0390|M.smegmatis_MC2_155 --NPRLRDYATARVLRIFP-GLWVCLLIIAFVMAPIGVLLQGGSVSGLMS
MAB_4106c|M.abscessus_ATCC_199 --KPKLRDFAIARGLRIFP-GLWVCLAIIAFVIAPTSVLIQGGSVSDLFA
MAV_3274|M.avium_104 --NPRLREYVAARALRILP-GLWVCLVVIAFVIAPIGVAIQGGSAAKLLM
Mflv_1859|M.gilvum_PYR-GCK TGRVGLKGFWIRRARRLLP-ALVVMVLAVVAVRGLFSDESVANLRDDAVA
Mvan_1670|M.vanbaalenii_PYR-1 G-DPSLRRFYSDRLRRIVPAATVVLVLTVVASVYLLPQPAVRDITFDALF
: * *:.* . : :
Mb0233|M.bovis_AF2122/97 ANLTLTQIYVP----LTLTGGLT-----QMWSLSVEVAFYAALPVLALLG
Rv0228|M.tuberculosis_H37Rv ANLTLTQIYVP----LTLTGGLT-----QMWSLSVEVAFYAALPVLALLG
MMAR_4188|M.marinum_M RNLTLTQIYTDGYLGSYLHQGLT-----QMWSLAVEASFYVLLPFLAYLL
MUL_4492|M.ulcerans_Agy99 RNLTLTQIYTDGYLGSYLHQGLT-----QMWSLAVEASFYVLLPFLAYLL
MLBr_01101|M.leprae_Br4923 RNLTLTQIYTDGYLGSYLHQGLT-----QMWSLAVEVAFYVALPLLAYLL
TH_2230|M.thermoresistible__bu RNLTHTQIYTDNYLYSYLHQGLT-----QMWSLAVEVAFYAVLPLLAYLL
MSMEG_0390|M.smegmatis_MC2_155 SYAPIEYVLNNAVLNVYYAGING-----TPQGIPWPGVWNGSLWTLVFEM
MAB_4106c|M.abscessus_ATCC_199 SHKPIEYVINNGLLNVYYAGVDG-----TPRGVPWPGVWNGSIWTLVFEM
MAV_3274|M.avium_104 SRAPIEYVLHNAVLHVFFAGIDG-----TPRHVPFPGVWDGVLWTLIFEI
Mflv_1859|M.gilvum_PYR-GCK TFFWMSNWIFVAQDTDYFSQGAPPSPLQHTWSLAVEEQYYVLWPLLIAAV
Mvan_1670|M.vanbaalenii_PYR-1 AFFFVANWHFAAAGTDIPATIDSVSPLLHYWPLSIEEQFLLVWPVLIVAI
:. : *
Mb0233|M.bovis_AF2122/97 ------RRIPV---------GARVPAIAALAALSWAWGWLPLDAGSGIN-
Rv0228|M.tuberculosis_H37Rv ------RRIPV---------GARVPAIAALAALSWAWGWLPLDAGSGIN-
MMAR_4188|M.marinum_M LVVISRRRWQP---------KLVVGALLAMATITPGWLVLIHTVSLFPDG
MUL_4492|M.ulcerans_Agy99 LVVISRRRWQP---------KLVVGALLAMATITPGWLVLIHTVSLFPDG
MLBr_01101|M.leprae_Br4923 LVLLCQRRWQP---------RLVLVVLAGMLLISPGWLILVHPDHWFPDG
TH_2230|M.thermoresistible__bu LVVVCRRRWRP---------GLLLTGLAVLAAISPAWLYLVHTVDWLPDG
MSMEG_0390|M.smegmatis_MC2_155 ICY------------------IAVAVLGIVGLLKRRWVIPAIFVLTLCAT
MAB_4106c|M.abscessus_ATCC_199 ICY------------------IAVAVLGVAGLLKRRWVVPAAFVFFLAAT
MAV_3274|M.avium_104 FCY------------------IAIAVAGVAGLLKRRWPAVVVFILLVVFS
Mflv_1859|M.gilvum_PYR-GCK IAGLTALAYRRGMTLSQRAVRTAVFLLATAGIVASATATALMSSDGNLNR
Mvan_1670|M.vanbaalenii_PYR-1 TLIAVRGAWSHAR-------WLTTTAVVMGVVVAASFGGALYQTSTSPDW
:
Mb0233|M.bovis_AF2122/97 PLTWPPAFFSWFAA-----GMLLAEWAYSPVGLPHRWARRRVAMAVTALL
Rv0228|M.tuberculosis_H37Rv PLTWPPAFFSWFAA-----GMLLAEWAYSPVGLPHRWARRRVAMAVTALL
MMAR_4188|M.marinum_M ARLWLPSYLAWFLG-----GMLLTVLQAMKV------QCYALAALPLATI
MUL_4492|M.ulcerans_Agy99 ARLWLPSYLAWFLG-----GMLLTVLQAMKV------QCYALAALPLATI
MLBr_01101|M.leprae_Br4923 ARLWLPTYLAWFLG-----GMILAVLQVMGV------RCYAFGAIPLAII
TH_2230|M.thermoresistible__bu ARLWLPTYLIWFLG-----GMMLAALQPMGV------RAYALVCIPLALI
MSMEG_0390|M.smegmatis_MC2_155 AYFSYPVFAMQTIP-----QMVARFAVMFAAG-ALIHQYRDVIPARWSLV
MAB_4106c|M.abscessus_ATCC_199 AYLSYPVFAATSIP-----QMVARFAVMFAAG-ALLNQYKDILPARWSLV
MAV_3274|M.avium_104 ALVAYPV-EVQTVF-----QMIGRFALVFAAG-TLLHQFQDKIPARWSLV
Mflv_1859|M.gilvum_PYR-GCK VYFGTDTRVQALLVGAAAAALLVRDWRGLTAGLEIFRSRWARWVAWSLPV
Mvan_1670|M.vanbaalenii_PYR-1 AYLSTATRAWELGIG----ALLATAAGTFAR----IPELLRPVLSWAGVA
::
Mb0233|M.bovis_AF2122/97 GYLVAASPLAGPEGLVPGTAAQFAVKTAMGSLVAFALVAPLVLDRPDTSH
Rv0228|M.tuberculosis_H37Rv GYLVAASPLAGPEGLVPGTAAQFAVKTAMGSLVAFALVAPLVLDRPDTSH
MMAR_4188|M.marinum_M CYFIVATPIAGAPTTSPSALTEAVVKACFYTVIATLAVAPLALGDQGWYS
MUL_4492|M.ulcerans_Agy99 CYFIVATPIAGAPTTSPSALTEAVVKACFYTVIATLAVAPLALGDQGWYS
MLBr_01101|M.leprae_Br4923 CYFIVSTPIAGAPTTSPASLGEALIKVGFYAAIATLAVAPLTLGDLGWYS
TH_2230|M.thermoresistible__bu CYFIVATPIGGEPTTSPNELWEAWAKTGFYTVIATLMVAPLALGNKGWYS
MSMEG_0390|M.smegmatis_MC2_155 GIAVVLVLASGFLS-NYRVIGALPLAYAVIVAGALLRNRRLNLRNDLSYG
MAB_4106c|M.abscessus_ATCC_199 ALSVAIVLVSGLLE-NYRDVAALPLAYAVIVSGSLIHKPRLNLRNDLSYG
MAV_3274|M.avium_104 ALSAVIVLAAGLLMPNYRVLAAIPLAYAVVVSGALIHHERLRLRTDLSYG
Mflv_1859|M.gilvum_PYR-GCK VGLVVLFLAARIATGSVEEFRSG--LLIVVALAAVLVIAPVALAQDGPVA
Mvan_1670|M.vanbaalenii_PYR-1 LVVAAVFLIDGSAG--------FPAPWALLPVAGAALVVAAGIGREPGFQ
. . . :
Mb0233|M.bovis_AF2122/97 RLLGSPAMVTLGRWSYGLFIWH----------------LAALAMVFP-VI
Rv0228|M.tuberculosis_H37Rv RLLGSPAMVTLGRWSYGLFIWH----------------LAALAMVFP-VI
MMAR_4188|M.marinum_M QLLASRPMVWLGEISYEIFLVH----------------LVTMEFAMVYVV
MUL_4492|M.ulcerans_Agy99 QLLASRPMVWLGEISYEIFLVH----------------LVTMEFAMVYVV
MLBr_01101|M.leprae_Br4923 WLLSSRPMVWLGEISYEIFLIH----------------LVTMEFAMVYVV
TH_2230|M.thermoresistible__bu RVLGSRPMVFLGEISYEIFLIH----------------LILMEVAMVEIL
MSMEG_0390|M.smegmatis_MC2_155 VYIYAFPVQQLLAILGFANSQP----------------FLFFVIATAATV
MAB_4106c|M.abscessus_ATCC_199 TYIYAYPIQQLLVVSGLASLNL----------------LLFFVIATVATV
MAV_3274|M.avium_104 VYIYAWPMQQLLAICGLSFLPP----------------VVFAVVAVVVTL
Mflv_1859|M.gilvum_PYR-GCK RLLSVWPLVGLGAISYGVYLWHWPIFLILNGERTGASGWQLFALRCAATI
Mvan_1670|M.vanbaalenii_PYR-1 GLLRNRASTYLGDLSYALYLVHWP-------------VIVLLAVVMAPNV
: . * . :
Mb0233|M.bovis_AF2122/97 GAFPFTGRMPTVLVLTLIFGFAIAAVSYALVESPCREALRRWERRNEPIS
Rv0228|M.tuberculosis_H37Rv GAFPFTGRMPTVLVLTLIFGFAIAAVSYALVESPCREALRRWERRNEPIS
MMAR_4188|M.marinum_M RYRVYTGSMLNLFIATMVITIPLAWVLHRFTRVRSE--------------
MUL_4492|M.ulcerans_Agy99 RYWVYTGSMLNLFIATMVITIPLAWVLHRFTRVRSE--------------
MLBr_01101|M.leprae_Br4923 QDHVYTGSMLNLIVATLVLTIPLAWLLHRCTRMRS---------------
TH_2230|M.thermoresistible__bu RSPVYTGSMFWLFVWTMVLTIPLAWLLHRFTRVRDQ--------------
MSMEG_0390|M.smegmatis_MC2_155 PLAALSWFLVEKRAIALKSRLKRRRT--DTVADTTQKVSDRGAG------
MAB_4106c|M.abscessus_ATCC_199 PLAAFSWFVVEKRAIALKSRLTRKQA--VTVAERPPIPLDRDAA------
MAV_3274|M.avium_104 PLAALSWFLVEKRALSLKSRIKRRARGWGAVVSSGSRISTPGS-------
Mflv_1859|M.gilvum_PYR-GCK AVAAVSWWLIEQPVREWRPAFVPMLPLAGATAATAAVLTMTVLPVRVVPP
Mvan_1670|M.vanbaalenii_PYR-1 YFYASVLTLTLGLAVACHHFVENPLRYASLDALRQAREDMRHNLFHVELS
: .
Mb0233|M.bovis_AF2122/97 VGELQADAIAP---------------------------------------
Rv0228|M.tuberculosis_H37Rv VGELQADAIAP---------------------------------------
MMAR_4188|M.marinum_M --------------------------------------------------
MUL_4492|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01101|M.leprae_Br4923 --------------------------------------------------
TH_2230|M.thermoresistible__bu --------------------------------------------------
MSMEG_0390|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4106c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_3274|M.avium_104 --------------------------------------------------
Mflv_1859|M.gilvum_PYR-GCK TPEPGPLVDIAALVGPEVPVEVTRAPTPRAPGDLRVAVFGDSIAWTMMRY
Mvan_1670|M.vanbaalenii_PYR-1 TKIAGVAALVLITLSVISFAMGPDALHHTDPAQTDTTNVSP---------
Mb0233|M.bovis_AF2122/97 --------------------------------------------------
Rv0228|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4188|M.marinum_M --------------------------------------------------
MUL_4492|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01101|M.leprae_Br4923 --------------------------------------------------
TH_2230|M.thermoresistible__bu --------------------------------------------------
MSMEG_0390|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4106c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_3274|M.avium_104 --------------------------------------------------
Mflv_1859|M.gilvum_PYR-GCK LPDTPGVDFADFTTIGCGIARGGPYEYVGQELQQKPECDEWPARWAQRIG
Mvan_1670|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb0233|M.bovis_AF2122/97 --------------------------------------------------
Rv0228|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4188|M.marinum_M --------------------------------------------------
MUL_4492|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01101|M.leprae_Br4923 --------------------------------------------------
TH_2230|M.thermoresistible__bu --------------------------------------------------
MSMEG_0390|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4106c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_3274|M.avium_104 --------------------------------------------------
Mflv_1859|M.gilvum_PYR-GCK HQKPDVVLLMVGRWEVVDRMSEGRWTHIGEPGYDAYLRSELNRALDILGS
Mvan_1670|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb0233|M.bovis_AF2122/97 --------------------------------------------------
Rv0228|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4188|M.marinum_M --------------------------------------------------
MUL_4492|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01101|M.leprae_Br4923 --------------------------------------------------
TH_2230|M.thermoresistible__bu --------------------------------------------------
MSMEG_0390|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4106c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_3274|M.avium_104 --------------------------------------------------
Mflv_1859|M.gilvum_PYR-GCK TGARLVVATEPYNRRAEKADGSLYPEDQPDRVERWNTMLREVVDERPNAT
Mvan_1670|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb0233|M.bovis_AF2122/97 -------------------------------------------------
Rv0228|M.tuberculosis_H37Rv -------------------------------------------------
MMAR_4188|M.marinum_M -------------------------------------------------
MUL_4492|M.ulcerans_Agy99 -------------------------------------------------
MLBr_01101|M.leprae_Br4923 -------------------------------------------------
TH_2230|M.thermoresistible__bu -------------------------------------------------
MSMEG_0390|M.smegmatis_MC2_155 -------------------------------------------------
MAB_4106c|M.abscessus_ATCC_199 -------------------------------------------------
MAV_3274|M.avium_104 -------------------------------------------------
Mflv_1859|M.gilvum_PYR-GCK VLDLNEKLSPNGYYQMRVNGLKVRSDGVHPTPEAVEWMTPWLVEAIRTP
Mvan_1670|M.vanbaalenii_PYR-1 -------------------------------------------------