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TKAGATGQAKGLTLGQVFDPRNNALNAWRLALAVSVIFWHSWPLTGRTITYRPFEQLIEQVGVDGFFAVS GFLITASWLRKPKLRDFAIARGLRIFPGLWVCLAIIAFVIAPTSVLIQGGSVSDLFASHKPIEYVINNGL LNVYYAGVDGTPRGVPWPGVWNGSIWTLVFEMICYIAVAVLGVAGLLKRRWVVPAAFVFFLAATAYLSYP VFAATSIPQMVARFAVMFAAGALLNQYKDILPARWSLVALSVAIVLVSGLLENYRDVAALPLAYAVIVSG SLIHKPRLNLRNDLSYGTYIYAYPIQQLLVVSGLASLNLLLFFVIATVATVPLAAFSWFVVEKRAIALKS RLTRKQAVTVAERPPIPLDRDAA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4106c | - | - | 100% (374) | acetyltransferase |
| M. abscessus ATCC 19977 | MAB_3448 | - | e-134 | 66.47% (343) | putative acetyltransferase |
| M. abscessus ATCC 19977 | MAB_1725c | - | e-128 | 64.55% (347) | putative acetyltransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0530 | - | 2e-06 | 24.93% (357) | membrane acyltransferase |
| M. gilvum PYR-GCK | Mflv_1859 | - | 2e-07 | 25.21% (349) | acyltransferase 3 |
| M. tuberculosis H37Rv | Rv0517 | - | 2e-06 | 24.93% (357) | membrane acyltransferase |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_0857 | - | 7e-06 | 25.36% (351) | transmembrane acyltransferase |
| M. avium 104 | MAV_3274 | - | 1e-124 | 60.83% (360) | putative acyltransferase |
| M. smegmatis MC2 155 | MSMEG_0390 | - | 1e-154 | 72.42% (359) | putative acyltransferase |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_0609 | - | 4e-06 | 25.64% (351) | transmembrane acyltransferase |
| M. vanbaalenii PYR-1 | Mvan_4875 | - | 3e-07 | 24.35% (345) | acyltransferase 3 |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0857|M.marinum_M MTIRQDRSASQLRAAQRPGPRIAFRPDIEGLRAIAVVAVVLYHAGIPGIS
MUL_0609|M.ulcerans_Agy99 ---------------------------------------MSCHAGIPGIS
Mflv_1859|M.gilvum_PYR-GCK --MTAVSAAPIRVGPRRYVGPGQSIPALDGVRAIAVALVLADHGGVPGLS
Mvan_4875|M.vanbaalenii_PYR-1 --MTAVSAAPIRVGPRRYVGPGQAIPALDGVRAIAVALVLADHGGVPGLS
Mb0530|M.bovis_AF2122/97 -----------------------------------MAGGMDQPPGQPRRR
Rv0517|M.tuberculosis_H37Rv -----------------------------------MAGGMDQPPGQPRRR
MAB_4106c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_0390|M.smegmatis_MC2_155 --------------------------------------------------
MAV_3274|M.avium_104 ---------------------------------------MSADPNVSDPT
MMAR_0857|M.marinum_M GGYIGVDVFFVISGFLITGLLWSEVTTTNTVALGRFYGARARRLLPAAAT
MUL_0609|M.ulcerans_Agy99 GGYIGVDVFFVISGFLITGLLWREVTTTNTVALGRFYGARARRLLPAAAT
Mflv_1859|M.gilvum_PYR-GCK GGFLGVDVFFVLSGFLITSLLLDEIGRTGRVGLKGFWIRRARRLLPALVV
Mvan_4875|M.vanbaalenii_PYR-1 GGFLGVDVFFVLSGFLITSLLLDEVGRTGRIGLKGFWIRRARRLLPALLV
Mb0530|M.bovis_AF2122/97 TRQQSSDGKNGVRAAEITGEIRALTG-------LRIVAAVWVVLFHFRPM
Rv0517|M.tuberculosis_H37Rv TRQQSSDGKNGVRAAEITGEIRALTG-------LRIVAAVWVVLFHFRPM
MAB_4106c|M.abscessus_ATCC_199 --MTKAGATGQAKGLTLGQVFDPRNN----------ALNAWRLALAVSVI
MSMEG_0390|M.smegmatis_MC2_155 ----------------MGKVFDPRNN----------ALNALRLLLAVGVI
MAV_3274|M.avium_104 TIAARGPARRRVPGPTLAQVFDTRIN----------ALNVWRLVLASGVI
: : :
MMAR_0857|M.marinum_M VGVATAIVSAIVLPPLQARRVFVDGIASALYVGNYRFAVQGTDYMASDLP
MUL_0609|M.ulcerans_Agy99 VGVATAIVSAIVLPPLQARRVFVDGIASALYVGNYRFAVQGTDYMASDLP
Mflv_1859|M.gilvum_PYR-GCK MVLAVVAVRGLFSDESVAN-LRDDAVATFFWMSNWIFVAQDTDYFSQGAP
Mvan_4875|M.vanbaalenii_PYR-1 MVLAVVALRELFSEESTAN-LREDAVAAFFWMSNWVFVAQHTDYFSQGAP
Mb0530|M.bovis_AF2122/97 LGDASPGFRDALAPVLDCG---AQGVDLFFILSGFVLTWNYLDRMGR---
Rv0517|M.tuberculosis_H37Rv LGDASPGFRDALAPVLDCG---AQGVDLFFILSGFVLTWNYLDRMGR---
MAB_4106c|M.abscessus_ATCC_199 FWHSWPLTGRTITYRPFEQLIEQVGVDGFFAVSGFLITASWLR-------
MSMEG_0390|M.smegmatis_MC2_155 LWHSWPLSGHGVTYKPLEQLLEQVWVDGFFAISGFLITSSWLR-------
MAV_3274|M.avium_104 LQHSWPLTGR-KVHPPYDQLFPQVWVDGFFAISGFLIAASWVR-------
. : : : :..: :. .
MMAR_0857|M.marinum_M PSPFQHYWSLGVEEQFYLVWPALIIATAWLLRRIGKNN-----RGATPYA
MUL_0609|M.ulcerans_Agy99 PSPFQHYWSLGVEDQFYLVWPALIIATAWLLRRIGKNN-----RGATPYA
Mflv_1859|M.gilvum_PYR-GCK PSPLQHTWSLAVEEQYYVLWPLLIAAVIAGLTALAYRRGMTLSQRAVRTA
Mvan_4875|M.vanbaalenii_PYR-1 PSPLQHTWSLAVEEQFYVLWPLLIAAVLAGLAALAYRRGVPLSQRVVRTA
Mb0530|M.bovis_AF2122/97 --------SWSVRANLHFLWLRLARVWPVYLVTL---------HLAAVWV
Rv0517|M.tuberculosis_H37Rv --------SWSVRANLHFLWLRLARVWPVYLVTL---------HLAAVWV
MAB_4106c|M.abscessus_ATCC_199 --------KPKLRDFAIARGLRIFPGLWVCLAIIA-------------FV
MSMEG_0390|M.smegmatis_MC2_155 --------NPRLRDYATARVLRIFPGLWVCLLIIA-------------FV
MAV_3274|M.avium_104 --------NPRLREYVAARALRILPGLWVCLVVIA-------------FV
. :. : * : .
MMAR_0857|M.marinum_M VVLVLVAAASLAAAAIWTRTSP---PWAFFSLPTRAWELAVGG-LVALTM
MUL_0609|M.ulcerans_Agy99 VVLVLVAAASLAAAAIWTRTSP---PWAFFSLPTRAWELAVGG-LVALTM
Mflv_1859|M.gilvum_PYR-GCK VFLLATAGIVASATATALMSSDGNLNRVYFGTDTRVQALLVGAAAAALLV
Mvan_4875|M.vanbaalenii_PYR-1 VFVLAAGGVVASATATFFLSSDATLNRVYFGTDTRVQALLVGAAAAALVV
Mb0530|M.bovis_AF2122/97 IFTLHVGHVPSPEAGQLTAISY---VRQILLVQLWFQPYFDGS---SWDG
Rv0517|M.tuberculosis_H37Rv IFTLHVGHVPSPEAGQLTAISY---VRQILLVQLWFQPYFDGS---SWDG
MAB_4106c|M.abscessus_ATCC_199 IAPTSVLIQGGSVSDLFASHKP-----IEYVINNGLLNVYYAGVDGTPRG
MSMEG_0390|M.smegmatis_MC2_155 MAPIGVLLQGGSVSGLMSSYAP-----IEYVLNNAVLNVYYAGINGTPQG
MAV_3274|M.avium_104 IAPIGVAIQGGSAAKLLMSRAP-----IEYVLHNAVLHVFFAGIDGTPRH
: . . : .. :
MMAR_0857|M.marinum_M QQWRRLPL------------VPATIVGWGGLALLLLTCTQLGPNTPYPGT
MUL_0609|M.ulcerans_Agy99 QQWRRLPL------------VPATIVGWGGLALLLLTCTQLGPNTPYPGT
Mflv_1859|M.gilvum_PYR-GCK RDWRGLTAGLEIFRSRWARWVAWSLPVVGLVVLFLAARIATGSVEEFRSG
Mvan_4875|M.vanbaalenii_PYR-1 RDWRGLTAGLVIFRSRWARWVAWSLPAVGLVVLFSAARMATGSAAEFRSG
Mb0530|M.bovis_AF2122/97 PAWS----------------ISAEWLAYLLFGLLILVIFRMKHATRARG-
Rv0517|M.tuberculosis_H37Rv PAWS----------------ISAEWLAYLLFGLLILVIFRMKHATRARG-
MAB_4106c|M.abscessus_ATCC_199 VPWPG---------------VWNGSIWTLVFEMICYIAVAVLGVAGLLKR
MSMEG_0390|M.smegmatis_MC2_155 IPWPG---------------VWNGSLWTLVFEMICYIAVAVLGIVGLLKR
MAV_3274|M.avium_104 VPFPG---------------VWDGVLWTLIFEIFCYIAIAVAGVAGLLKR
: : . ::
MMAR_0857|M.marinum_M AALLPVLGTALVIGSGCVTGSMGVGRVLCRPVMRAIGRVSYSWYLWHWPV
MUL_0609|M.ulcerans_Agy99 AALLPVLGTALVIGSGCVTGAMGVGRVLCRPVMRAIGRVSYSWYLWHWPV
Mflv_1859|M.gilvum_PYR-GCK LLIVVALAAVLVIAPVALAQDGPVARLLSVWPLVGLGAISYGVYLWHWPI
Mvan_4875|M.vanbaalenii_PYR-1 LLIVVALAAVLVIAPVALAQDGPVARLLSAGPLVGLGAISYGVYLWHWPI
Mb0530|M.bovis_AF2122/97 ---LMWLAFAASLPPVVLLLASG----QFYTPWSWLPRIVTQFAAGALAC
Rv0517|M.tuberculosis_H37Rv ---LMWLAFAASLPPVVLLLASG----QFYTPWSWLPRIVTQFAAGALAC
MAB_4106c|M.abscessus_ATCC_199 RWVVPAAFVFFLAATAYLS--------YPVFAATSIPQMVARFAVMFAAG
MSMEG_0390|M.smegmatis_MC2_155 RWVIPAIFVLTLCATAYFS--------YPVFAMQTIPQMVARFAVMFAAG
MAV_3274|M.avium_104 RWPAVVVFILLVVFSALVA--------YPV-EVQTVFQMIGRFALVFAAG
. . : : .
MMAR_0857|M.marinum_M LLLLPPLLGDPAGLPARLAATTVSAGLAVITMYLVENPGRFTAALRSVRA
MUL_0609|M.ulcerans_Agy99 LLLLPPLLGDPAGLPARLAATTVSAGLAVITMYLVENPGRFTAALRSVRA
Mflv_1859|M.gilvum_PYR-GCK FLILNGERTGASGWQLFALRCAATIAVAAVSWWLIEQP---VREWRPAFV
Mvan_4875|M.vanbaalenii_PYR-1 FLVLNGERTGIEGWELFALRCAATVAVAAVSWWLIEQP---IREWRPAFV
Mb0530|M.bovis_AF2122/97 AAVRRLRPTDRARRIAGYLSVLVGVAIVGILYLLHAHP------------
Rv0517|M.tuberculosis_H37Rv AAVRRLRPTDRARRIAGYLSVLVGVAIVGILYLLHAHP------------
MAB_4106c|M.abscessus_ATCC_199 ALLNQYKDILPARWSLVALSVAIVLVSGLLE-NYRDVA------------
MSMEG_0390|M.smegmatis_MC2_155 ALIHQYRDVIPARWSLVGIAVVLVLASGFLS-NYRVIG------------
MAV_3274|M.avium_104 TLLHQFQDKIPARWSLVALSAVIVLAAGLLMPNYRVLA------------
: :
MMAR_0857|M.marinum_M SLTLAAAATAAAACACALLLTAIPVPVGHGTAAPEAKIIALPPAALPQRA
MUL_0609|M.ulcerans_Agy99 SLTLAAAATAAAACACALLLTAIPVPVGHGTAASEAKIIALPPAALPQRA
Mflv_1859|M.gilvum_PYR-GCK PMLPLAGATAATAAVLTMTVLPVRVVPPTPEPGPLVDIAALVGPEVPVEV
Mvan_4875|M.vanbaalenii_PYR-1 PMLPLAAATAATAAVVTMTVLPVRMVPATPEPGPEVDIAALVGAEVPVEV
Mb0530|M.bovis_AF2122/97 -----LAGVEDSGGVVDVLFVPLVISLAIG--------------------
Rv0517|M.tuberculosis_H37Rv -----LAGVEDSGGVVDVLFVPLVISLAIG--------------------
MAB_4106c|M.abscessus_ATCC_199 -ALPLAYAVIVSGSLIHKPRLNLRNDLSYG--------------------
MSMEG_0390|M.smegmatis_MC2_155 -ALPLAYAVIVAGALLRNRRLNLRNDLSYG--------------------
MAV_3274|M.avium_104 -AIPLAYAVVVSGALIHHERLRLRTDLSYG--------------------
.. :. :
MMAR_0857|M.marinum_M LSPQEAAVQQAFAAVRAAVAASAG---LGAVPSNLNPPLAAAPGDKAAVF
MUL_0609|M.ulcerans_Agy99 LSPQEAAVQQAFAAVRAAVAASAG---LGAVPSTLNPPLAAAPGDKAAVF
Mflv_1859|M.gilvum_PYR-GCK TR---APTPRAPGDLRVAVFGDS-------IAWTMMRYLPDTPG------
Mvan_4875|M.vanbaalenii_PYR-1 TR---APRPSAPGDLRVAVFGDS-------IAWTLMRYLPETPG------
Mb0530|M.bovis_AF2122/97 -----VGSLPALLSTRLMVFGGQISFCLY---------------------
Rv0517|M.tuberculosis_H37Rv -----VGSLPALLSTRLMVFGGQISFCLY---------------------
MAB_4106c|M.abscessus_ATCC_199 -----TYIYAYPIQQLLVVSGLAS--------------------------
MSMEG_0390|M.smegmatis_MC2_155 -----VYIYAFPVQQLLAILGFAN--------------------------
MAV_3274|M.avium_104 -----VYIYAWPMQQLLAICGLSF--------------------------
. : .
MMAR_0857|M.marinum_M VNGCLRSWRDLGQSECATADTASPTTVALVGDSHAAMWDPALQLVAEQRH
MUL_0609|M.ulcerans_Agy99 VNGCLRSWRDLAQSECATADTASPTTVALVGDSHAAMWDPALQLVAEQRH
Mflv_1859|M.gilvum_PYR-GCK --------VDFADFTTIGCGIARGGPYEYVG--------QELQQKPECDE
Mvan_4875|M.vanbaalenii_PYR-1 --------LDFADYTTIGCGIARGGPYEYVG--------QELPQKPECDE
Mb0530|M.bovis_AF2122/97 ---------------------------------------MVHELVHTAWG
Rv0517|M.tuberculosis_H37Rv ---------------------------------------MVHELVHTAWG
MAB_4106c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_0390|M.smegmatis_MC2_155 --------------------------------------------------
MAV_3274|M.avium_104 --------------------------------------------------
MMAR_0857|M.marinum_M WRLETLAKVTCPMQDLPILSPYLGREYTECEQWRGEIMGRLQSERPRLVV
MUL_0609|M.ulcerans_Agy99 WRLETLAKVTCPMQDLPILSPYLGREYTECEQWRGEIMGRLQSERPRLVV
Mflv_1859|M.gilvum_PYR-GCK WPARWAQRIGHQKPDVVLLMVG-----------RWEVVDRMSEGR-----
Mvan_4875|M.vanbaalenii_PYR-1 WPARWAQRVGHEKPDVVLLMVG-----------RWEVVDRMMEGQ-----
Mb0530|M.bovis_AF2122/97 WAVQQYELALQDQP------------------WKWNVVG-----------
Rv0517|M.tuberculosis_H37Rv WAVQQYELALQDQP------------------WKWNVVG-----------
MAB_4106c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_0390|M.smegmatis_MC2_155 --------------------------------------------------
MAV_3274|M.avium_104 --------------------------------------------------
MMAR_0857|M.marinum_M LSMSRRYQPDFSFASYDPAWIDTLNRTVAQLRRNGSSVLVLGPVADPQSS
MUL_0609|M.ulcerans_Agy99 LSMSRRYQPDFSFASYDPAWIDTLNRTVAQLRRNGSSVLVLGPVADPQSS
Mflv_1859|M.gilvum_PYR-GCK -------WTHIGEPGYDAYLRSELNRALDILGSTGARLVVA--------T
Mvan_4875|M.vanbaalenii_PYR-1 -------WTHIGEAGYDAYLRGELNRALDILGSTGARVVVT--------T
Mb0530|M.bovis_AF2122/97 ------------------LLAIALGAAILLYHFVE---------------
Rv0517|M.tuberculosis_H37Rv ------------------LLAIALGAAILLYHFVE---------------
MAB_4106c|M.abscessus_ATCC_199 -------------------LNLLLFFVIATVATVP---------------
MSMEG_0390|M.smegmatis_MC2_155 -------------------SQPFLFFVIATAATVP---------------
MAV_3274|M.avium_104 -------------------LPPVVFAVVAVVVTLP---------------
: .:
MMAR_0857|M.marinum_M VPTCLSAHLDDAGACAPSRSAATNAGGVAAEQTATEAGGGHYADLTDLFC
MUL_0609|M.ulcerans_Agy99 VPTCLSAHLDDAGACAPSRSAATNAGGVAAEQTATEAGGGHYADLTDLFC
Mflv_1859|M.gilvum_PYR-GCK EPYNRRAEKADGSLYPEDQPDRVERWNTMLREVVDERPNATVLDLNEKLS
Mvan_4875|M.vanbaalenii_PYR-1 EPYNRRAEKPDGSLYPEDQPKRVETWNALLRSVVDKRPNATVLDLNKKLS
Mb0530|M.bovis_AF2122/97 EPDRRWMRRMVDVKAASARSEPGEPVGSTRYQIDDALEGVSARAV-----
Rv0517|M.tuberculosis_H37Rv EPGRRWMRRMVDVKAASARSEPGEPVGSTRYQIDDALEGVSARAV-----
MAB_4106c|M.abscessus_ATCC_199 LAAFSWFVVEKRAIALKSRLTRKQA--VTVAERPPIPLDRDAA-------
MSMEG_0390|M.smegmatis_MC2_155 LAALSWFLVEKRAIALKSRLKRRRT--DTVADTTQKVSDRGAG-------
MAV_3274|M.avium_104 LAALSWFLVEKRALSLKSRIKRRARGWGAVVSSGSRISTPGS--------
. : .
MMAR_0857|M.marinum_M TPDRCPTIIGNTLVFRDDNHLTTEYAQLLAPVIGALADRALAAG
MUL_0609|M.ulcerans_Agy99 TPDRCPTIIGNTLVFRDDNHLTTEYAQLLAPVIGALADRALAAG
Mflv_1859|M.gilvum_PYR-GCK PNGYYQMRVNGLKVRSDGVHPTPEAVEWMTPWLVEAIRTP----
Mvan_4875|M.vanbaalenii_PYR-1 PNGYYQTRVDGIRVRSDGVHPTPEAVEWLTPWLVDALKPE----
Mb0530|M.bovis_AF2122/97 --------------------------------------------
Rv0517|M.tuberculosis_H37Rv --------------------------------------------
MAB_4106c|M.abscessus_ATCC_199 --------------------------------------------
MSMEG_0390|M.smegmatis_MC2_155 --------------------------------------------
MAV_3274|M.avium_104 --------------------------------------------