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NPEHETVIIGAGIGGLGAAIGLKRAGLTDFVILERSAGIGGTWYNNHYPDVAVDVPGIVYQFSFAKNPNW SRTFPKGREVQQYIAGLVDQYRLNDHLRLGHEVMARVWDEDNHLWRLTLADGRVITSRFVITAVGAFVEP KVPDIAGLESFGGKVIQTQNWDHDYDLSGKRIAVIGTGATSVQLIPQMARVASHLDVYQRRAIWVFAKPD FPIPRAARWALKYIPGLQSLIRGIAAAAVEVGLVAITVYGKQIAPITLIPNWACRAFLFTQVRDRELRKK LTPEYGFGCKRPSVSNIYYRTFTQPHVDLVTDPIAEITPTGIVTRDGVRRDIDVLVLATGFEMSQSPEVY RARPVKGRNGFDLADYYENNRARAYEGVTMPQLPNTFMVFGPFAWSGSSWHVMVENATRIAVRVITEARK RGATAFAVTEEANNRFFEFIAPKAESTLMHGRACVNANSYYIDRHGDFSFLRPTTAYQSTRASKRFPLDD FRFDRLPEPKSPQLAETATTRSN*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4042c | - | - | 100% (514) | monooxygenase |
| M. abscessus ATCC 19977 | MAB_4050c | - | e-125 | 44.64% (504) | monooxygenase |
| M. abscessus ATCC 19977 | MAB_0140c | - | e-119 | 43.37% (498) | monooxygenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1428c | - | 1e-119 | 43.41% (493) | monoxygenase |
| M. gilvum PYR-GCK | Mflv_4607 | - | 1e-118 | 43.36% (512) | cyclohexanone monooxygenase |
| M. tuberculosis H37Rv | Rv1393c | - | 1e-119 | 43.41% (493) | monoxygenase |
| M. leprae Br4923 | MLBr_00065 | - | 1e-30 | 27.19% (434) | putative monooxygenase |
| M. marinum M | MMAR_2207 | - | 1e-121 | 42.94% (496) | monoxygenase |
| M. avium 104 | MAV_2172 | - | 1e-119 | 43.85% (488) | FAD dependent oxidoreductase, putative |
| M. smegmatis MC2 155 | MSMEG_0816 | - | 1e-116 | 43.06% (490) | flavin-binding monooxygenase |
| M. thermoresistible (build 8) | TH_2450 | - | 1e-104 | 38.51% (509) | PUTATIVE putative FAD dependent oxidoreductase |
| M. ulcerans Agy99 | MUL_1793 | - | 1e-116 | 42.74% (489) | monoxygenase |
| M. vanbaalenii PYR-1 | Mvan_0721 | - | 1e-117 | 44.04% (495) | FAD-dependent pyridine nucleotide-disulphide oxidoreductase |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_0816|M.smegmatis_MC2_155 ------------------MRPVVHDAVIVGAGFAGLGAAIQLK-KMSFDD
Mvan_0721|M.vanbaalenii_PYR-1 ------------------MISEHFDAVIVGAGFAGIGAAIQFK-RMGIEN
MAV_2172|M.avium_104 ------------------MVTDRFDAIIVGAGFGGIGAAIQLK-RLGFDN
Mb1428c|M.bovis_AF2122/97 -------------------MMPDYHALIVGAGFSGIGAAIKLD-RAGFSD
Rv1393c|M.tuberculosis_H37Rv -------------------MMPDYHALIVGAGFSGIGAAIKLD-RAGFSD
MMAR_2207|M.marinum_M -----------------MSIEPDYQIVIVGAGFSGIGAAISLD-KAGFGD
MUL_1793|M.ulcerans_Agy99 --------------------------MIVGAGFSGIGAAISLD-KAGFGD
Mflv_4607|M.gilvum_PYR-GCK MSVHVAGDENAPTSGAPTYEVPTHEILVIGAGFSGIGVGIKLL-KEGFSD
MAB_4042c|M.abscessus_ATCC_199 -------------------MNPEHETVIIGAGIGGLGAAIGLK-RAGLTD
TH_2450|M.thermoresistible__bu -------------MTVTGDVRPEYDVAIIGAGPGGIAAAHKLR-RRGITD
MLBr_00065|M.leprae_Br4923 --------------MVVMAETEYLDVVIVGAGISGVSAAWHLQDRCPNKS
::*** .*:... : : .
MSMEG_0816|M.smegmatis_MC2_155 FVILEREDDLGGTWYVNHYPGLAVDVPTTTYSYFFEPNPSWSRLFSTGRE
Mvan_0721|M.vanbaalenii_PYR-1 FVILEREDDLGGTWYVNHYPGLAVDVPTTTYSYFFEPNPNWSRLFSTGAE
MAV_2172|M.avium_104 IVILDREDDLGGTWHVNHYPGIAVDIPSTTYSYWFEPNPGWSRLFAPGGE
Mb1428c|M.bovis_AF2122/97 YLVVEAGDGVGGTWHWNTYPGIAVDIPSFSYQFSFEQSRHWSRTYAPGHE
Rv1393c|M.tuberculosis_H37Rv YLVVEAGDGVGGTWHWNTYPGIAVDIPSFSYQFSFEQSRHWSRTYAPGHE
MMAR_2207|M.marinum_M YLVIEAGDGVGGTWFWNTYPGIAVDIPSFSYQFSFEQSPDWSRSYAPGRE
MUL_1793|M.ulcerans_Agy99 YLVIEAGDAVGGTWFWNTYPGIAVDIPSFSYQFSFEQSPDWSRSYAPGRE
Mflv_4607|M.gilvum_PYR-GCK FLIVDEAQGVGGTWYWNTYPGIAVDIPSYSYQFSFEKRPSWSRTYAPGIE
MAB_4042c|M.abscessus_ATCC_199 FVILERSAGIGGTWYNNHYPDVAVDVPGIVYQFSFAKNPNWSRTFPKGRE
TH_2450|M.thermoresistible__bu IAILERGDDFGGTWRDNHYPGLAVDIPILWYQFSFNRNPRWSRVFAPGPE
MLBr_00065|M.leprae_Br4923 YVILEKRAGMGGTWDLFRYPGIRSDSDMYTLGFRFRP-WTKCQAIADGKP
::: .**** **.: * : * .: . *
MSMEG_0816|M.smegmatis_MC2_155 IKRYADDVADKYDVRRHIRFGTTVTGARWDEDDNVWQVSLTDGEQ---LQ
Mvan_0721|M.vanbaalenii_PYR-1 IKQYADDVADKYDVRRHIRFGVTVGGARWDDDAQLWRVNLADGET---VD
MAV_2172|M.avium_104 VKQYAADVADKYDVRRHMRFNTTVEGAQWDEDAEVWRVALAGGES---LT
Mb1428c|M.bovis_AF2122/97 LKAYAEHCVDKYGIRSRIRLNTKVLAAEFDDEHSLWRVQTDPGGE---IT
Rv1393c|M.tuberculosis_H37Rv LKAYAEHCVDKYGIRSRIRLNTKVLAAEFDDEHSLWRVQTDPGGE---IT
MMAR_2207|M.marinum_M LRAYAEHCADKYGIRPRIRFNTKVLGAEFDDERSLWRLQTDPGGE---LT
MUL_1793|M.ulcerans_Agy99 LRAYAEHCADKYGIRPRIRFNTKVLGAELDDERSLWRLQTDPGGD---LI
Mflv_4607|M.gilvum_PYR-GCK LKNYAKHCVKKYGLASRIRFGVTVVRAEFDEESTLWRLFTSTDEE---LT
MAB_4042c|M.abscessus_ATCC_199 VQQYIAGLVDQYRLNDHLRLGHEVMARVWDEDNHLWRLTLADGRV---IT
TH_2450|M.thermoresistible__bu IHRYLTDTARSLGLYPLLRPHHDVVGQRWNAENAMWQLTVRDRPP---VT
MLBr_00065|M.leprae_Br4923 ILEYIKSTAVMHGIDKYIRLNHKVTGADWSSIENRWTVQVENNGTPRMIS
: * . : :* * . * : :
MSMEG_0816|M.smegmatis_MC2_155 ARFLITATGFLSQPH--TPDIPGITEFDGKVIHTTDWDDGCSLYGRRAAV
Mvan_0721|M.vanbaalenii_PYR-1 ARYLVTATGFLSQPH--MPDIPGIAEFDGRVIHTTAWDDSYDPTGEKIGI
MAV_2172|M.avium_104 TRFLITATGFLSQPH--TPDIPGIGSFGGKVVHTTAWDHDYRYQGRRIAV
Mb1428c|M.bovis_AF2122/97 ARFLISACGILTVPK--LPDIDGVDSFEGVTMHTARWDHTQDLTGKRVGI
Rv1393c|M.tuberculosis_H37Rv ARFLISACGILTVPK--LPDIDGVDSFEGVTMHTARWDHTQDLTGKRVGI
MMAR_2207|M.marinum_M TRFIINASGVLTVPK--LPDIAGVDSFAGVTMHTARWDHSQELTGKRVGI
MUL_1793|M.ulcerans_Agy99 TRFIINASGVLTVPK--LPDIAGVDSFAGVTMHTARWDHSQELTGKRVGI
Mflv_4607|M.gilvum_PYR-GCK ARFVINASGVLTRPK--SPDIPGVGDFGGVTMHTSRWDHQQTLTGKRVAV
MAB_4042c|M.abscessus_ATCC_199 SRFVITAVGAFVEPK--VPDIAGLESFGGKVIQTQNWDHDYDLSGKRIAV
TH_2450|M.thermoresistible__bu ARFVISSVGGYVNAR--ATDLEGLSDFTGKVLRPNCWDDGYDTRDKRVAV
MLBr_00065|M.leprae_Br4923 CSFLFLCSGYYNYEQGYAPTFLGSEDFTGPIIHPQHWPEDLDYAAKNIVV
::. . * : . : * .* * ::. * . .. :
MSMEG_0816|M.smegmatis_MC2_155 VGTGATAVQLIPELAER-VAELTVYQRTPIWVVPKVDVRFPPAVRALFAR
Mvan_0721|M.vanbaalenii_PYR-1 IGTGATAVQLIPELAEK-AADLTVYQRTPIWVVPKIDFRFSERAKQLFAR
MAV_2172|M.avium_104 IGTGASAVQVVPELAKE-AEELTVYQRTATHVLPKVDFEFDPAVRRLFAR
Mb1428c|M.bovis_AF2122/97 IGTGASAVQVIPEMAPI-VSHLTVFQRTPIWCFPKFDVPLPTAVRWAMRI
Rv1393c|M.tuberculosis_H37Rv IGTGASAVQVIPEMAPI-VSHLTVFQRTPIWCFPKFDVPLPTAVRWAMRI
MMAR_2207|M.marinum_M IGTGASAVQVIPEIAPI-VKHLTVFQRTPIWCFPKFDFPLPAALRWAMRI
MUL_1793|M.ulcerans_Agy99 IGTGASAVQVIPEIAPI-VKHLTVFQRTPIWCFPKFDFPLPAALRWAMRI
Mflv_4607|M.gilvum_PYR-GCK IGTGASAVQLIPSIAKD-VDTLTVFQRTPIWCLPKFDFAVPRPLSALLRL
MAB_4042c|M.abscessus_ATCC_199 IGTGATSVQLIPQMARV-ASHLDVYQRRAIWVFAKPDFPIPRAARWALKY
TH_2450|M.thermoresistible__bu IGTGSSGAQIVSALSGR-VARLDVYQRTPNWILPRPDFALPRALQRVLEL
MLBr_00065|M.leprae_Br4923 IGSGATAVTLVPALANSGAKHVTMLQRSPTYIVSQPAKDKIAARLNRWLP
:*:*::.. ::. :: . : : ** . ..:
MSMEG_0816|M.smegmatis_MC2_155 VPLTQRVVRAITDAIYAFMVDTAVLKHRYFR-R---------LNIAAADL
Mvan_0721|M.vanbaalenii_PYR-1 IPLTQRLIRVITDTIYELMVWVAVLHNRQTRGR---------FNIAAGDL
MAV_2172|M.avium_104 VPAAQRALRWVTDVLLEIIMIVGALHFKESRGR---------GNISASDL
Mb1428c|M.bovis_AF2122/97 P-GGKAVHRLLSQAFVEATFPIAAHYFAVFP-----------LAKHMESA
Rv1393c|M.tuberculosis_H37Rv P-GGKAVHRLLSQAFVEATFPIAAHYFAVFP-----------LAKHMESA
MMAR_2207|M.marinum_M P-GGKALQRLLSQAYVEATFPISAHYFTVFP-----------LARWSAVL
MUL_1793|M.ulcerans_Agy99 P-GGKALQRLLSQAYVEATFPISAHYFTVFP-----------LARWSAVL
Mflv_4607|M.gilvum_PYR-GCK APGAQIAARGASQAFVELTFPVAAHFHTAIP-----------LASAIERA
MAB_4042c|M.abscessus_ATCC_199 IPGLQSLIRGIAAAAVEVGLVAITVYGKQIAP----------ITLIPNWA
TH_2450|M.thermoresistible__bu P-GVAAVLHNIGRAVFDLFFVVPIVHLMAHVPDRVLVRLLRGYDSLARFA
MLBr_00065|M.leprae_Br4923 DKYAYTAVRWKNILRQSALYGACQKWPQRMR------------NILLGHV
:
MSMEG_0816|M.smegmatis_MC2_155 GRLHLAASIRDPDLRSKLTPDYDFGCKRPTFSNSYYRTFTKPHVHLQADG
Mvan_0721|M.vanbaalenii_PYR-1 AKMHRFATIRDKELRAKLTPDYDFGCKRPTFSNSYYRTFTKPHVHLQDSG
MAV_2172|M.avium_104 AKINRFRWIRDKELRAKLTPDYDCGCKRPTFSNSFYRVLTQPNVHLETNP
Mb1428c|M.bovis_AF2122/97 GRRYLRQQVHDPVVREQLTPRYAVGCKRPGFHNTYLSTFNRDNVRLVTEP
Rv1393c|M.tuberculosis_H37Rv GRRYLRQQVHDPVVREQLTPRYAVGCKRPGFHNTYLSTFNRDNVRLVTEP
MMAR_2207|M.marinum_M GRRYLRQRVNDPVVRDQLTPRYAVGCKRPGFHNGYLSTFNRDNVQLVTEP
MUL_1793|M.ulcerans_Agy99 GRRYLRQRVDDPVVRDQLTPRYAVDCKRPGFHNGYLSTFNRDNVQLVTEP
Mflv_4607|M.gilvum_PYR-GCK AISYMRRQVTDPVVREKLTPRYALGCKRPSFHNEYLKTFNRENVLLETNP
MAB_4042c|M.abscessus_ATCC_199 CRAFLFTQVRDRELRKKLTPEYGFGCKRPSVSNIYYRTFTQPHVDLVTDP
TH_2450|M.thermoresistible__bu FRVLLRAVVHDPQTRRRLMPAHGILAKRPIISGSYLPAFNDPRTHLITTP
MLBr_00065|M.leprae_Br4923 ARRLPKGYDVQKHFGPHYNPWEQRLCLVP--DGDLFRAIRKGTVDMVTDA
: : * . * . .: . :
MSMEG_0816|M.smegmatis_MC2_155 IDHVEPDGIVNADGSKTVIDTLVLATGFDL-WEAN-FPAIEVIGRQGRDL
Mvan_0721|M.vanbaalenii_PYR-1 IARIESDGIVGNDGTKTPIDTLVLATGFDL-WEAN-FPAIEVIGRDGRNL
MAV_2172|M.avium_104 IERIEPDGIVTADGRKNVIDTLVLATGFDL-WEAN-FPAIEVIGRKGRNL
Mb1428c|M.bovis_AF2122/97 IDKITPTAVATTDGASHEIDVLVLATGFKV-LDTDSIPTYAVTGTGGASL
Rv1393c|M.tuberculosis_H37Rv IDKITPTAVATTDGASHEIDVLVLATGFKV-LDTDSIPTYAVTGTGGASL
MMAR_2207|M.marinum_M IEKITPTAVATDDGTDHEIDVLILATGFKV-LDTDDVLTYPVIGRAGRSL
MUL_1793|M.ulcerans_Agy99 IEKITPTSVATDDGTDHEIDVLILATGFKV-LDTDDVLTYPVIGRAGRSL
Mflv_4607|M.gilvum_PYR-GCK ITRVDETAVITADGVRHEIDVLVLATGFKV-MESDSMPTYSLRGVAGRDQ
MAB_4042c|M.abscessus_ATCC_199 IAEITPTGIVTRDGVRRDIDVLVLATGFEMSQSPEVYRARPVKGRNGFDL
TH_2450|M.thermoresistible__bu IERITAAGVRTTDGVERPVDLIVTATGYELWTDPETYFPGTILGDAGFDL
MLBr_00065|M.leprae_Br4923 IDRFTSTGIRLKSGNELRADIIVTATGLNL---------QLFGGAVATVD
* .. .: .* * :: *** .: . * .
MSMEG_0816|M.smegmatis_MC2_155 GKWWRETRFQAYQGVSMPYFPNYLSLAGPYAFLGLNFFNTMEYQMRLMER
Mvan_0721|M.vanbaalenii_PYR-1 GKWWRETRFQAYQGVSMPHFPNFLSLASPFAFLGLNFFNTVEYQMRHMDR
MAV_2172|M.avium_104 GKWWRETRFQAYQGVSMPYFPNYLSLASPFAFSGLSFFHTIEYQMRHMDR
Mb1428c|M.bovis_AF2122/97 SRFWDEHRLQAYEGVSVPGYPNFFTVFGPYGYVGSSYFALIETQAHHIIR
Rv1393c|M.tuberculosis_H37Rv SRFWDEHRLQAYEGVSVPGYPNFFTVFGPYGYVGSSYFALIETQAHHIIR
MMAR_2207|M.marinum_M SQFWEEHRAQAYQGVSVPGYPNFFAVFGPYGYVGSSYFALIETQTHHILR
MUL_1793|M.ulcerans_Agy99 SQFWEEHRAQAYQGVSVPGYRNFFAVFGPYGYVGSSYFALIETQTHHILR
Mflv_4607|M.gilvum_PYR-GCK AQWWDENRLQAYEGVSVPGFPNHFSVFGPYGYNGSSYFALIEAQAGHILR
MAB_4042c|M.abscessus_ATCC_199 ADYYENNRARAYEGVTMPQLPNTFMVFGPFAWSGSSWHVMVENATRIAVR
TH_2450|M.thermoresistible__bu ALDYRENGLRSYGGTAHPRLPNRWEIVGPLAFVGVGWTDFVETMAEHAVR
MLBr_00065|M.leprae_Br4923 GQPVDLAQTMSYKGMMLSGLPNMIYTVG---YTNASWTLKADLVSEFFCR
. :* * . * . : . .: : *
MSMEG_0816|M.smegmatis_MC2_155 LLGEVARRDARTFEVTEEANRRYLDRMTDALGDSLFTLGNCAS-ARSYYF
Mvan_0721|M.vanbaalenii_PYR-1 LFGELRRRGATTFEITEEANARYLARMTALLGDSLFTNGSCAT-ARSYYF
MAV_2172|M.avium_104 LLGEVKRRGATTFEVTEEANDRFMERMTKLLDNSVFYAGNCAT-SRSYYF
Mb1428c|M.bovis_AF2122/97 CLKRARRTGATRIEVTEEANARYFAEVMRRRHRQVFWQDSCRL-ANSYYF
Rv1393c|M.tuberculosis_H37Rv CLKRARRTGATRIEVTEEANARYFAEVMRRRHRQVFWQDSCRL-ANSYYF
MMAR_2207|M.marinum_M CLKRARRDGATRVEVTEEANARYFAEMMRRRYRQVFWQDSCRR-ANSYYF
MUL_1793|M.ulcerans_Agy99 CLKRARRDGATRVEVTEEANARYFAEMMRRRYRQVFWQDSCRR-ANSYYF
Mflv_4607|M.gilvum_PYR-GCK CLRHARTADSNYVEVREEANQRFFAEMLARRHTQVFWQDSCAG-ANSYYF
MAB_4042c|M.abscessus_ATCC_199 VITEARKRGATAFAVTEEANNRFFEFIAPKAESTLMHGRACVN-ANSYYI
TH_2450|M.thermoresistible__bu IIDAARRRGADVVTVTDEAFGRWDARMRKAGKAARLYYTRCNPGVNTYYV
MLBr_00065|M.leprae_Br4923 LLNYMNANDFDTVAVEYPGSDVEERPFMDFTPGYVLRSLDALP-KQGSRT
: . . : . . : . .
MSMEG_0816|M.smegmatis_MC2_155 NPSGEATLLRPMTTRRAVAEASRFPLSDYTFA------------------
Mvan_0721|M.vanbaalenii_PYR-1 NPSGEPTLLRPTSTRAAIREATDFPIDDYRIV------------------
MAV_2172|M.avium_104 SPSGEASLLRPTSTLNSIREASSFPLSDYVIA------------------
Mb1428c|M.bovis_AF2122/97 DKNGD-VPLRPTTTVEAYWRSRRFDLGDYRISS-----------------
Rv1393c|M.tuberculosis_H37Rv DKNGD-VPLRPTTTVEAYWRSRRFDLGDYRISS-----------------
MMAR_2207|M.marinum_M DKNGD-VPLRPTTTVEAYWRGRHFDLDNYRFGR-----------------
MUL_1793|M.ulcerans_Agy99 DKNGD-VPLRPTTTVEAYWRGRHFDLDDYRFGR-----------------
Mflv_4607|M.gilvum_PYR-GCK DKHGD-VPLRPTTTVESIWRSRRFDLADYRFERRPAKKADTAPQKVDTAG
MAB_4042c|M.abscessus_ATCC_199 DRHGDFSFLRPTTAYQSTRASKRFPLDDFRFDRLPEPKSPQLAETATTRS
TH_2450|M.thermoresistible__bu NSQRDTVYHRPQTITESLVFAHRPPLTDYRFERRPAAARSAVRALRHAEG
MLBr_00065|M.leprae_Br4923 PWRLNQNYLRDIRLIRRGKVADEGLLFAKKTTPVTV--------------
: * . :
MSMEG_0816|M.smegmatis_MC2_155 ----
Mvan_0721|M.vanbaalenii_PYR-1 ----
MAV_2172|M.avium_104 ----
Mb1428c|M.bovis_AF2122/97 ----
Rv1393c|M.tuberculosis_H37Rv ----
MMAR_2207|M.marinum_M ----
MUL_1793|M.ulcerans_Agy99 ----
Mflv_4607|M.gilvum_PYR-GCK ----
MAB_4042c|M.abscessus_ATCC_199 N---
TH_2450|M.thermoresistible__bu NEAV
MLBr_00065|M.leprae_Br4923 ----