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STHTLPQHEVLVVGAGFGGIAAGVRLRRAGIDDFVIVDKHPSVGGTWFVNKYPGVAVDIPSFIYSFSFAQ TGKWSRLFAPGEELQQYAEDVVDGHGLRDKLRLGTTVLGSRFDEDTDIWHVETDRGEITARHVIVGIGGL EVPNLPDIPGIGSFGGKLLHTTAWDHDYDLTGKRVAVIGTGATALQLVPAIADQVSRLTVFQRTAIWVAP KLDFKTGPVSRFVFGNRLLRTPLRGVGMALVELGLGGALLGGQLLGQRLYKTVLQGVGLALRGWMWTQLP HDPELRKKLTPTYAFGCKRPSMHNEWFSTFTKPNVDLITEPIERITENSVITADGTEHEIDVLVCATGFK VMEKGATPPFPCLGRGGTDLNTWWDENRYQAYQGVTVPGWPNAYMLIGPWAYSPGSYLVLLESTVAHAVR AITETRRRGATRCEVRQEPHDKYWQQMLSRAAKSHLLTPLCAGSNTYYINYQGDAAAYRPSTNTEMRLQN RYFPFSDYEFTTTQARQLVAESVG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_0140c | - | - | 100% (515) | monooxygenase |
| M. abscessus ATCC 19977 | MAB_4024c | - | e-163 | 53.62% (511) | monooxygenase |
| M. abscessus ATCC 19977 | MAB_0513 | - | e-140 | 50.30% (503) | putative monooxygenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1428c | - | 1e-123 | 45.22% (502) | monoxygenase |
| M. gilvum PYR-GCK | Mflv_4607 | - | 1e-127 | 45.87% (508) | cyclohexanone monooxygenase |
| M. tuberculosis H37Rv | Rv1393c | - | 1e-123 | 45.22% (502) | monoxygenase |
| M. leprae Br4923 | MLBr_00065 | - | 4e-29 | 26.12% (402) | putative monooxygenase |
| M. marinum M | MMAR_2207 | - | 1e-124 | 43.53% (510) | monoxygenase |
| M. avium 104 | MAV_3378 | - | 1e-126 | 45.17% (507) | lipolytic enzyme |
| M. smegmatis MC2 155 | MSMEG_0816 | - | 1e-110 | 40.81% (495) | flavin-binding monooxygenase |
| M. thermoresistible (build 8) | TH_2450 | - | 1e-84 | 36.78% (503) | PUTATIVE putative FAD dependent oxidoreductase |
| M. ulcerans Agy99 | MUL_1793 | - | 1e-119 | 43.17% (505) | monoxygenase |
| M. vanbaalenii PYR-1 | Mvan_2671 | - | 1e-120 | 45.74% (505) | cyclohexanone monooxygenase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1428c|M.bovis_AF2122/97 -------------------MMPDYHALIVGAGFSGIGAAIKLD-RAGFSD
Rv1393c|M.tuberculosis_H37Rv -------------------MMPDYHALIVGAGFSGIGAAIKLD-RAGFSD
MMAR_2207|M.marinum_M -----------------MSIEPDYQIVIVGAGFSGIGAAISLD-KAGFGD
MUL_1793|M.ulcerans_Agy99 --------------------------MIVGAGFSGIGAAISLD-KAGFGD
MAV_3378|M.avium_104 ---------------MSSPAVPDHHTLIIGAGFSGIGAAIKLD-KAGLPD
Mvan_2671|M.vanbaalenii_PYR-1 --------------------MHDVETVIVGAGFSGIGAAIGLD-RVGMSD
Mflv_4607|M.gilvum_PYR-GCK MSVHVAGDENAPTSGAPTYEVPTHEILVIGAGFSGIGVGIKLL-KEGFSD
MAB_0140c|M.abscessus_ATCC_199 ---------------MSTHTLPQHEVLVVGAGFGGIAAGVRLR-RAGIDD
MSMEG_0816|M.smegmatis_MC2_155 ------------------MRPVVHDAVIVGAGFAGLGAAIQLK-KMSFDD
TH_2450|M.thermoresistible__bu -------------MTVTGDVRPEYDVAIIGAGPGGIAAAHKLR-RRGITD
MLBr_00065|M.leprae_Br4923 --------------MVVMAETEYLDVVIVGAGISGVSAAWHLQDRCPNKS
::*** .*:... * : .
Mb1428c|M.bovis_AF2122/97 YLVVEAGDGVGGTWHWNTYPGIAVDIPSFSYQFSFEQSRHWSRTYAPGHE
Rv1393c|M.tuberculosis_H37Rv YLVVEAGDGVGGTWHWNTYPGIAVDIPSFSYQFSFEQSRHWSRTYAPGHE
MMAR_2207|M.marinum_M YLVIEAGDGVGGTWFWNTYPGIAVDIPSFSYQFSFEQSPDWSRSYAPGRE
MUL_1793|M.ulcerans_Agy99 YLVIEAGDAVGGTWFWNTYPGIAVDIPSFSYQFSFEQSPDWSRSYAPGRE
MAV_3378|M.avium_104 YRVIEAGDGVGGTWHWNTYPGIAVDIPSFSYQFSFEQSRHWSRTYAPGRE
Mvan_2671|M.vanbaalenii_PYR-1 YVVVEAGDEPGGTWYWNTYPGIAVDIPSFSYQFSFEQSSAWSRTYAHGHE
Mflv_4607|M.gilvum_PYR-GCK FLIVDEAQGVGGTWYWNTYPGIAVDIPSYSYQFSFEKRPSWSRTYAPGIE
MAB_0140c|M.abscessus_ATCC_199 FVIVDKHPSVGGTWFVNKYPGVAVDIPSFIYSFSFAQTGKWSRLFAPGEE
MSMEG_0816|M.smegmatis_MC2_155 FVILEREDDLGGTWYVNHYPGLAVDVPTTTYSYFFEPNPSWSRLFSTGRE
TH_2450|M.thermoresistible__bu IAILERGDDFGGTWRDNHYPGLAVDIPILWYQFSFNRNPRWSRVFAPGPE
MLBr_00065|M.leprae_Br4923 YVILEKRAGMGGTWDLFRYPGIRSDSDMYTLGFRFRP-WTKCQAIADGKP
::: **** ***: * : * .: : *
Mb1428c|M.bovis_AF2122/97 LKAYAEHCVDKYGIRSRIRLNTKVLAAEFDDEHSLWRVQTDPGG---EIT
Rv1393c|M.tuberculosis_H37Rv LKAYAEHCVDKYGIRSRIRLNTKVLAAEFDDEHSLWRVQTDPGG---EIT
MMAR_2207|M.marinum_M LRAYAEHCADKYGIRPRIRFNTKVLGAEFDDERSLWRLQTDPGG---ELT
MUL_1793|M.ulcerans_Agy99 LRAYAEHCADKYGIRPRIRFNTKVLGAELDDERSLWRLQTDPGG---DLI
MAV_3378|M.avium_104 LKAYAEHCADKYGIRSRIRFNTKVLAAEFDDEQRLWRVQTDPGG---EVT
Mvan_2671|M.vanbaalenii_PYR-1 LKTYAEHCVDKYGLRPRIRFATTVRSADFDEAQGIWRLALDTADGPATLS
Mflv_4607|M.gilvum_PYR-GCK LKNYAKHCVKKYGLASRIRFGVTVVRAEFDEESTLWRLFTSTDE---ELT
MAB_0140c|M.abscessus_ATCC_199 LQQYAEDVVDGHGLRDKLRLGTTVLGSRFDEDTDIWHVETDRGE----IT
MSMEG_0816|M.smegmatis_MC2_155 IKRYADDVADKYDVRRHIRFGTTVTGARWDEDDNVWQVSLTDGE---QLQ
TH_2450|M.thermoresistible__bu IHRYLTDTARSLGLYPLLRPHHDVVGQRWNAENAMWQLTVRDRP---PVT
MLBr_00065|M.leprae_Br4923 ILEYIKSTAVMHGIDKYIRLNHKVTGADWSSIENRWTVQVENNGTPRMIS
: * . .: :* * . * : :
Mb1428c|M.bovis_AF2122/97 ARFLISACGILTVPK--LPDIDGVDSFEGVTMHTARWDHTQDLTGKRVGI
Rv1393c|M.tuberculosis_H37Rv ARFLISACGILTVPK--LPDIDGVDSFEGVTMHTARWDHTQDLTGKRVGI
MMAR_2207|M.marinum_M TRFIINASGVLTVPK--LPDIAGVDSFAGVTMHTARWDHSQELTGKRVGI
MUL_1793|M.ulcerans_Agy99 TRFIINASGVLTVPK--LPDIAGVDSFAGVTMHTARWDHSQELTGKRVGI
MAV_3378|M.avium_104 ARFLISACGVLTVPN--LPDIDGVDSFAGITMHTARWDHGQDLRGKRVAV
Mvan_2671|M.vanbaalenii_PYR-1 ARFLVNAGGVLTVPK--LPDIAGVDSFAGVTMHTARWDHTQDLRGKRVAI
Mflv_4607|M.gilvum_PYR-GCK ARFVINASGVLTRPK--SPDIPGVGDFGGVTMHTSRWDHQQTLTGKRVAV
MAB_0140c|M.abscessus_ATCC_199 ARHVIVGIGGLEVPN--LPDIPGIGSFGGKLLHTTAWDHDYDLTGKRVAV
MSMEG_0816|M.smegmatis_MC2_155 ARFLITATGFLSQPH--TPDIPGITEFDGKVIHTTDWDDGCSLYGRRAAV
TH_2450|M.thermoresistible__bu ARFVISSVGGYVNAR--ATDLEGLSDFTGKVLRPNCWDDGYDTRDKRVAV
MLBr_00065|M.leprae_Br4923 CSFLFLCSGYYNYEQGYAPTFLGSEDFTGPIIHPQHWPEDLDYAAKNIVV
.:. * . . : * .* * ::. * . :. :
Mb1428c|M.bovis_AF2122/97 IGTGASAVQVIPEMAP-IVSHLTVFQRTPIWCFPKFDVPLPTAVRWAMRI
Rv1393c|M.tuberculosis_H37Rv IGTGASAVQVIPEMAP-IVSHLTVFQRTPIWCFPKFDVPLPTAVRWAMRI
MMAR_2207|M.marinum_M IGTGASAVQVIPEIAP-IVKHLTVFQRTPIWCFPKFDFPLPAALRWAMRI
MUL_1793|M.ulcerans_Agy99 IGTGASAVQVIPEIAP-IVKHLTVFQRTPIWCFPKFDFPLPAALRWAMRI
MAV_3378|M.avium_104 IGTGASAVQVIPEIAP-IVSSLTVFQRTPIWCFPKLDVPLPAPARWAMRF
Mvan_2671|M.vanbaalenii_PYR-1 IGTGASAVQVIPEIAP-IVERLTVFQRTPIWCFPKFDVPLSKTAQTMMRL
Mflv_4607|M.gilvum_PYR-GCK IGTGASAVQLIPSIAK-DVDTLTVFQRTPIWCLPKFDFAVPRPLSALLRL
MAB_0140c|M.abscessus_ATCC_199 IGTGATALQLVPAIAD-QVSRLTVFQRTAIWVAPKLDFKTGPVSRFVFGN
MSMEG_0816|M.smegmatis_MC2_155 VGTGATAVQLIPELAE-RVAELTVYQRTPIWVVPKVDVRFPPAVRALFAR
TH_2450|M.thermoresistible__bu IGTGSSGAQIVSALSG-RVARLDVYQRTPNWILPRPDFALPRALQRVLEL
MLBr_00065|M.leprae_Br4923 IGSGATAVTLVPALANSGAKHVTMLQRSPTYIVSQPAKDKIAARLNRWLP
:*:*::. ::. :: . : : **:. : .:
Mb1428c|M.bovis_AF2122/97 P-GGKAVHRLLSQAFVEATFP-------IAAHYFAVFPLAKHMESAGRRY
Rv1393c|M.tuberculosis_H37Rv P-GGKAVHRLLSQAFVEATFP-------IAAHYFAVFPLAKHMESAGRRY
MMAR_2207|M.marinum_M P-GGKALQRLLSQAYVEATFP-------ISAHYFTVFPLARWSAVLGRRY
MUL_1793|M.ulcerans_Agy99 P-GGKALQRLLSQAYVEATFP-------ISAHYFTVFPLARWSAVLGRRY
MAV_3378|M.avium_104 P-GGKALQRLLSQAYVELTFP-------ISAHYFTVIPLAKRMAALGRAY
Mvan_2671|M.vanbaalenii_PYR-1 P-FGKSLQRLISQAFVELTFP-------LAAQYFTVNPMAKRMGAVGRAY
Mflv_4607|M.gilvum_PYR-GCK APGAQIAARGASQAFVELTFP-------VAAHFHTAIPLASAIERAAISY
MAB_0140c|M.abscessus_ATCC_199 R-LLRTPLRGVGMALVELGLGG----ALLGGQLLGQRLYKTVLQGVGLAL
MSMEG_0816|M.smegmatis_MC2_155 VPLTQRVVRAITDAIYAFMVDT----AVLKHRYFRRLNIA--AADLGRLH
TH_2450|M.thermoresistible__bu P-GVAAVLHNIGRAVFDLFFVVPIVHLMAHVPDRVLVRLLRGYDSLARFA
MLBr_00065|M.leprae_Br4923 DKYAYTAVRWKNILRQSALYG--------ACQKWPQRMRNILLGHVARRL
: .
Mb1428c|M.bovis_AF2122/97 ----LRQQVHDPVVREQLTPRYAVGCKRPGFHNTYLSTFNRDNVRLVTEP
Rv1393c|M.tuberculosis_H37Rv ----LRQQVHDPVVREQLTPRYAVGCKRPGFHNTYLSTFNRDNVRLVTEP
MMAR_2207|M.marinum_M ----LRQRVNDPVVRDQLTPRYAVGCKRPGFHNGYLSTFNRDNVQLVTEP
MUL_1793|M.ulcerans_Agy99 ----LRQRVDDPVVRDQLTPRYAVDCKRPGFHNGYLSTFNRDNVQLVTEP
MAV_3378|M.avium_104 ----LRRQVRDPAVREQLTPRYAVGCKRPGFHNGYLATFNRDNVRLVTEP
Mvan_2671|M.vanbaalenii_PYR-1 ----LRKQVDDPVLRDKLTPRYAVGCKRPGFHNTYLSTFNRDNVDLVTEP
Mflv_4607|M.gilvum_PYR-GCK ----MRRQVTDPVVREKLTPRYALGCKRPSFHNEYLKTFNRENVLLETNP
MAB_0140c|M.abscessus_ATCC_199 RGWMWTQLPHDPELRKKLTPTYAFGCKRPSMHNEWFSTFTKPNVDLITEP
MSMEG_0816|M.smegmatis_MC2_155 ----LAASIRDPDLRSKLTPDYDFGCKRPTFSNSYYRTFTKPHVHLQADG
TH_2450|M.thermoresistible__bu FRVLLRAVVHDPQTRRRLMPAHGILAKRPIISGSYLPAFNDPRTHLITTP
MLBr_00065|M.leprae_Br4923 P----KGYDVQKHFGPHYNPWEQRLCLVP--DGDLFRAIRKGTVDMVTDA
: : * . * . :: . : :
Mb1428c|M.bovis_AF2122/97 IDKITPTAVATTDGASHEIDVLVLATGFKVLDT----DSIPTYAVTGTGG
Rv1393c|M.tuberculosis_H37Rv IDKITPTAVATTDGASHEIDVLVLATGFKVLDT----DSIPTYAVTGTGG
MMAR_2207|M.marinum_M IEKITPTAVATDDGTDHEIDVLILATGFKVLDT----DDVLTYPVIGRAG
MUL_1793|M.ulcerans_Agy99 IEKITPTSVATDDGTDHEIDVLILATGFKVLDT----DDVLTYPVIGRAG
MAV_3378|M.avium_104 IDKITPDAVATTDGETHEIDVLILATGFKVMDP----DSVPTFAVTGSGG
Mvan_2671|M.vanbaalenii_PYR-1 IDKITGSGVSTTDGSLHEVDVLILATGFKVFAAHDGDDSVATFPVTGPGG
Mflv_4607|M.gilvum_PYR-GCK ITRVDETAVITADGVRHEIDVLVLATGFKVMES----DSMPTYSLRGVAG
MAB_0140c|M.abscessus_ATCC_199 IERITENSVITADGTEHEIDVLVCATGFKVMEK----GATPPFPCLGRGG
MSMEG_0816|M.smegmatis_MC2_155 IDHVEPDGIVNADGSKTVIDTLVLATGFDLWEA-----NFPAIEVIGRQG
TH_2450|M.thermoresistible__bu IERITAAGVRTTDGVERPVDLIVTATGYELWTDP---ETYFPGTILGDAG
MLBr_00065|M.leprae_Br4923 IDRFTSTGIRLKSGNELRADIIVTATGLNLQLFG------------GAVA
* :. .: .* * :: *** .: * .
Mb1428c|M.bovis_AF2122/97 ASLSRFWDEHRLQAYEGVSVPGYPNFFTVFGPYGYVGSSYFALIETQAHH
Rv1393c|M.tuberculosis_H37Rv ASLSRFWDEHRLQAYEGVSVPGYPNFFTVFGPYGYVGSSYFALIETQAHH
MMAR_2207|M.marinum_M RSLSQFWEEHRAQAYQGVSVPGYPNFFAVFGPYGYVGSSYFALIETQTHH
MUL_1793|M.ulcerans_Agy99 RSLSQFWEEHRAQAYQGVSVPGYRNFFAVFGPYGYVGSSYFALIETQTHH
MAV_3378|M.avium_104 RSLSRFWDEHRLQAYEGVTVPGFPNLFTVFGPYGYVGSSYFALIEAQTHH
Mvan_2671|M.vanbaalenii_PYR-1 RSLARFWDDNRLQAYEGVSVPGFPNFFTVFGPYGYVGSSYFALIEAQTRH
Mflv_4607|M.gilvum_PYR-GCK RDQAQWWDENRLQAYEGVSVPGFPNHFSVFGPYGYNGSSYFALIEAQAGH
MAB_0140c|M.abscessus_ATCC_199 TDLNTWWDENRYQAYQGVTVPGWPNAYMLIGPWAYSPGSYLVLLESTVAH
MSMEG_0816|M.smegmatis_MC2_155 RDLGKWWRETRFQAYQGVSMPYFPNYLSLAGPYAFLGLNFFNTMEYQMRL
TH_2450|M.thermoresistible__bu FDLALDYRENGLRSYGGTAHPRLPNRWEIVGPLAFVGVGWTDFVETMAEH
MLBr_00065|M.leprae_Br4923 TVDGQPVDLAQTMSYKGMMLSGLPNMIYTVG---YTNASWTLKADLVSEF
:* * . * * : .: :
Mb1428c|M.bovis_AF2122/97 IIRCLKRARRTGATRIEVTE---EANARYFAEVMRR-RHRQVFWQDSCRL
Rv1393c|M.tuberculosis_H37Rv IIRCLKRARRTGATRIEVTE---EANARYFAEVMRR-RHRQVFWQDSCRL
MMAR_2207|M.marinum_M ILRCLKRARRDGATRVEVTE---EANARYFAEMMRR-RYRQVFWQDSCRR
MUL_1793|M.ulcerans_Agy99 ILRCLKRARRDGATRVEVTE---EANARYFAEMMRR-RYRQVFWQDSCRR
MAV_3378|M.avium_104 IVRCLKRAQRLGATRVEVSE---EANDRYFAEMMRR-RHRQIFWQDSCRL
Mvan_2671|M.vanbaalenii_PYR-1 IVRCLDAARRRRATRVEVRR---EANDRYFAEMMRK-RHRQIFWQDSCQL
Mflv_4607|M.gilvum_PYR-GCK ILRCLRHARTADSNYVEVRE---EANQRFFAEMLAR-RHTQVFWQDSCAG
MAB_0140c|M.abscessus_ATCC_199 AVRAITETRRRGATRCEVRQ---EPHDKYWQQMLSR-AAKSHLLTPLCAG
MSMEG_0816|M.smegmatis_MC2_155 MERLLGEVARRDARTFEVTE---EANRRYLDRMTDA-LGDSLFTLGNCAS
TH_2450|M.thermoresistible__bu AVRIIDAARRRGADVVTVTD---EAFGRWDARMRKAGKAARLYYTRCNPG
MLBr_00065|M.leprae_Br4923 FCRLLNYMNANDFDTVAVEYPGSDVEERPFMDFTPGYVLRSLDALPKQGS
* : * : : .
Mb1428c|M.bovis_AF2122/97 ANSYYFDKNGD-VPLRPTTTVEAYWRSRRFDLGDYRISS-----------
Rv1393c|M.tuberculosis_H37Rv ANSYYFDKNGD-VPLRPTTTVEAYWRSRRFDLGDYRISS-----------
MMAR_2207|M.marinum_M ANSYYFDKNGD-VPLRPTTTVEAYWRGRHFDLDNYRFGR-----------
MUL_1793|M.ulcerans_Agy99 ANSYYFDKNGD-VPLRPTTTVEAYWRGRHFDLDDYRFGR-----------
MAV_3378|M.avium_104 ANSYYFDKNGD-VPLRPGTTPEVYWRSRRFDLDDYRFTG-----------
Mvan_2671|M.vanbaalenii_PYR-1 SNSYYFDQHGD-VPLRPASTPEAYWRSRRFPIDDYEFSC-----------
Mflv_4607|M.gilvum_PYR-GCK ANSYYFDKHGD-VPLRPTTTVESIWRSRRFDLADYRFERRPAKKADTAPQ
MAB_0140c|M.abscessus_ATCC_199 SNTYYINYQGDAAAYRPSTNTEMRLQNRYFPFSDYEFTTTQARQLVAESV
MSMEG_0816|M.smegmatis_MC2_155 ARSYYFNPSGEATLLRPMTTRRAVAEASRFPLSDYTFA------------
TH_2450|M.thermoresistible__bu VNTYYVNSQRDTVYHRPQTITESLVFAHRPPLTDYRFERRPAAARSAVRA
MLBr_00065|M.leprae_Br4923 RTPWRLN-QNYLRDIRLIRRGKVADEGLLFAKKTTPVTV-----------
.: .: * . .
Mb1428c|M.bovis_AF2122/97 ----------
Rv1393c|M.tuberculosis_H37Rv ----------
MMAR_2207|M.marinum_M ----------
MUL_1793|M.ulcerans_Agy99 ----------
MAV_3378|M.avium_104 ----------
Mvan_2671|M.vanbaalenii_PYR-1 ----------
Mflv_4607|M.gilvum_PYR-GCK KVDTAG----
MAB_0140c|M.abscessus_ATCC_199 G---------
MSMEG_0816|M.smegmatis_MC2_155 ----------
TH_2450|M.thermoresistible__bu LRHAEGNEAV
MLBr_00065|M.leprae_Br4923 ----------