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TASIPDHHVVVIGSGVGGLCAGVRLKQAGIEDFVIIDRAADLGGTWRDNVYPGIAVDIPSVIYQYSFFRN PHWSRVFAPGDEVQAYHQRVAENFGLRPHFRFGVDVRSEEWDEGQHHWRLNLADGSVMTARFVISAIGPF FDPKESGIKGIESFKGTRVTPSQWLPEHDVRGKRVAVIGTGATGVQLSGAIADDTASLVVFQRTPVYCIP KPDFRIPAIAQWALRIPGLTAAIEWGALVGGSVGLWFLINTPGVVMRPLMRLFDRAGRALYGAYLRAVVK DARVARDLLPSFGPLGNRPTLNSAFPRVFNKPHCDLVTTPIDEVVPEGVRTTDGTVYEADFLITATGFDL FSEPASYKRGRVIGAEGRDLGDFFNTHGMQAYESVSITGFPNRWIIVGPYSWTGNGGWHGLADTAVTHIV RAISLARERHATRMEVRQEALDRFHQSMLRNGRNLKYYFTELNRGVRSYWKNADDDVPLLRPTTTLQARR AARNFPAMDYVYEQHATNSTAAVVHSQATV*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4039c | - | - | 100% (521) | monooxygenase |
| M. abscessus ATCC 19977 | MAB_0142c | - | e-132 | 44.64% (513) | putative monooxygenase |
| M. abscessus ATCC 19977 | MAB_4017c | - | e-117 | 42.91% (501) | monooxygenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1428c | - | 6e-97 | 38.43% (497) | monoxygenase |
| M. gilvum PYR-GCK | Mflv_4607 | - | 3e-91 | 38.61% (505) | cyclohexanone monooxygenase |
| M. tuberculosis H37Rv | Rv1393c | - | 6e-97 | 38.43% (497) | monoxygenase |
| M. leprae Br4923 | MLBr_00065 | - | 3e-26 | 25.97% (412) | putative monooxygenase |
| M. marinum M | MMAR_2207 | - | 5e-96 | 39.56% (498) | monoxygenase |
| M. avium 104 | MAV_3378 | - | 1e-103 | 41.16% (498) | lipolytic enzyme |
| M. smegmatis MC2 155 | MSMEG_0816 | - | 5e-83 | 36.67% (499) | flavin-binding monooxygenase |
| M. thermoresistible (build 8) | TH_2450 | - | 1e-105 | 38.49% (517) | PUTATIVE putative FAD dependent oxidoreductase |
| M. ulcerans Agy99 | MUL_1793 | - | 3e-92 | 39.35% (493) | monoxygenase |
| M. vanbaalenii PYR-1 | Mvan_2671 | - | 4e-93 | 38.97% (503) | cyclohexanone monooxygenase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1428c|M.bovis_AF2122/97 -------------------MMPDYHALIVGAGFSGIGAAIKLDRAG-FSD
Rv1393c|M.tuberculosis_H37Rv -------------------MMPDYHALIVGAGFSGIGAAIKLDRAG-FSD
MMAR_2207|M.marinum_M -----------------MSIEPDYQIVIVGAGFSGIGAAISLDKAG-FGD
MUL_1793|M.ulcerans_Agy99 --------------------------MIVGAGFSGIGAAISLDKAG-FGD
MAV_3378|M.avium_104 ---------------MSSPAVPDHHTLIIGAGFSGIGAAIKLDKAG-LPD
Mvan_2671|M.vanbaalenii_PYR-1 --------------------MHDVETVIVGAGFSGIGAAIGLDRVG-MSD
Mflv_4607|M.gilvum_PYR-GCK MSVHVAGDENAPTSGAPTYEVPTHEILVIGAGFSGIGVGIKLLKEG-FSD
MSMEG_0816|M.smegmatis_MC2_155 ------------------MRPVVHDAVIVGAGFAGLGAAIQLKKMS-FDD
MAB_4039c|M.abscessus_ATCC_199 ----------------MTASIPDHHVVVIGSGVGGLCAGVRLKQAG-IED
TH_2450|M.thermoresistible__bu -------------MTVTGDVRPEYDVAIIGAGPGGIAAAHKLRRRG-ITD
MLBr_00065|M.leprae_Br4923 --------------MVVMAETEYLDVVIVGAGISGVSAAWHLQDRCPNKS
::*:* .*: .. * .
Mb1428c|M.bovis_AF2122/97 YLVVEAGDGVGGTWHWNTYPGIAVDIPSFSYQFSFEQSRHWSRTYAPGHE
Rv1393c|M.tuberculosis_H37Rv YLVVEAGDGVGGTWHWNTYPGIAVDIPSFSYQFSFEQSRHWSRTYAPGHE
MMAR_2207|M.marinum_M YLVIEAGDGVGGTWFWNTYPGIAVDIPSFSYQFSFEQSPDWSRSYAPGRE
MUL_1793|M.ulcerans_Agy99 YLVIEAGDAVGGTWFWNTYPGIAVDIPSFSYQFSFEQSPDWSRSYAPGRE
MAV_3378|M.avium_104 YRVIEAGDGVGGTWHWNTYPGIAVDIPSFSYQFSFEQSRHWSRTYAPGRE
Mvan_2671|M.vanbaalenii_PYR-1 YVVVEAGDEPGGTWYWNTYPGIAVDIPSFSYQFSFEQSSAWSRTYAHGHE
Mflv_4607|M.gilvum_PYR-GCK FLIVDEAQGVGGTWYWNTYPGIAVDIPSYSYQFSFEKRPSWSRTYAPGIE
MSMEG_0816|M.smegmatis_MC2_155 FVILEREDDLGGTWYVNHYPGLAVDVPTTTYSYFFEPNPSWSRLFSTGRE
MAB_4039c|M.abscessus_ATCC_199 FVIIDRAADLGGTWRDNVYPGIAVDIPSVIYQYSFFRNPHWSRVFAPGDE
TH_2450|M.thermoresistible__bu IAILERGDDFGGTWRDNHYPGLAVDIPILWYQFSFNRNPRWSRVFAPGPE
MLBr_00065|M.leprae_Br4923 YVILEKRAGMGGTWDLFRYPGIRSDSDMYTLGFRFRP-WTKCQAIADGKP
::: **** ***: * : * .: : *
Mb1428c|M.bovis_AF2122/97 LKAYAEHCVDKYGIRSRIRLNTKVLAAEFDDEHSLWRVQTDPGG---EIT
Rv1393c|M.tuberculosis_H37Rv LKAYAEHCVDKYGIRSRIRLNTKVLAAEFDDEHSLWRVQTDPGG---EIT
MMAR_2207|M.marinum_M LRAYAEHCADKYGIRPRIRFNTKVLGAEFDDERSLWRLQTDPGG---ELT
MUL_1793|M.ulcerans_Agy99 LRAYAEHCADKYGIRPRIRFNTKVLGAELDDERSLWRLQTDPGG---DLI
MAV_3378|M.avium_104 LKAYAEHCADKYGIRSRIRFNTKVLAAEFDDEQRLWRVQTDPGG---EVT
Mvan_2671|M.vanbaalenii_PYR-1 LKTYAEHCVDKYGLRPRIRFATTVRSADFDEAQGIWRLALDTADGPATLS
Mflv_4607|M.gilvum_PYR-GCK LKNYAKHCVKKYGLASRIRFGVTVVRAEFDEESTLWRLFTSTDE---ELT
MSMEG_0816|M.smegmatis_MC2_155 IKRYADDVADKYDVRRHIRFGTTVTGARWDEDDNVWQVSLTDGE---QLQ
MAB_4039c|M.abscessus_ATCC_199 VQAYHQRVAENFGLRPHFRFGVDVRSEEWDEGQHHWRLNLADGS---VMT
TH_2450|M.thermoresistible__bu IHRYLTDTARSLGLYPLLRPHHDVVGQRWNAENAMWQLTVRDRP---PVT
MLBr_00065|M.leprae_Br4923 ILEYIKSTAVMHGIDKYIRLNHKVTGADWSSIENRWTVQVENNGTPRMIS
: * . .: :* * . * : :
Mb1428c|M.bovis_AF2122/97 ARFLISACGILTVPK--LPDIDGVDSFEGVTMHTARWDHTQDLTGKRVGI
Rv1393c|M.tuberculosis_H37Rv ARFLISACGILTVPK--LPDIDGVDSFEGVTMHTARWDHTQDLTGKRVGI
MMAR_2207|M.marinum_M TRFIINASGVLTVPK--LPDIAGVDSFAGVTMHTARWDHSQELTGKRVGI
MUL_1793|M.ulcerans_Agy99 TRFIINASGVLTVPK--LPDIAGVDSFAGVTMHTARWDHSQELTGKRVGI
MAV_3378|M.avium_104 ARFLISACGVLTVPN--LPDIDGVDSFAGITMHTARWDHGQDLRGKRVAV
Mvan_2671|M.vanbaalenii_PYR-1 ARFLVNAGGVLTVPK--LPDIAGVDSFAGVTMHTARWDHTQDLRGKRVAI
Mflv_4607|M.gilvum_PYR-GCK ARFVINASGVLTRPK--SPDIPGVGDFGGVTMHTSRWDHQQTLTGKRVAV
MSMEG_0816|M.smegmatis_MC2_155 ARFLITATGFLSQPH--TPDIPGITEFDGKVIHTTDWDDGCSLYGRRAAV
MAB_4039c|M.abscessus_ATCC_199 ARFVISAIGPFFDPK--ESGIKGIESFKGTRVTPSQWLPEHDVRGKRVAV
TH_2450|M.thermoresistible__bu ARFVISSVGGYVNAR--ATDLEGLSDFTGKVLRPNCWDDGYDTRDKRVAV
MLBr_00065|M.leprae_Br4923 CSFLFLCSGYYNYEQGYAPTFLGSEDFTGPIIHPQHWPEDLDYAAKNIVV
*:. . * . . : * .* * : . * :. :
Mb1428c|M.bovis_AF2122/97 IGTGASAVQVIPEMAP-IVSHLTVFQRTPIWCFPKFDVPLPTAVRWAMRI
Rv1393c|M.tuberculosis_H37Rv IGTGASAVQVIPEMAP-IVSHLTVFQRTPIWCFPKFDVPLPTAVRWAMRI
MMAR_2207|M.marinum_M IGTGASAVQVIPEIAP-IVKHLTVFQRTPIWCFPKFDFPLPAALRWAMRI
MUL_1793|M.ulcerans_Agy99 IGTGASAVQVIPEIAP-IVKHLTVFQRTPIWCFPKFDFPLPAALRWAMRI
MAV_3378|M.avium_104 IGTGASAVQVIPEIAP-IVSSLTVFQRTPIWCFPKLDVPLPAPARWAMRF
Mvan_2671|M.vanbaalenii_PYR-1 IGTGASAVQVIPEIAP-IVERLTVFQRTPIWCFPKFDVPLSKTAQTMMRL
Mflv_4607|M.gilvum_PYR-GCK IGTGASAVQLIPSIAK-DVDTLTVFQRTPIWCLPKFDFAVPRPLSALLRL
MSMEG_0816|M.smegmatis_MC2_155 VGTGATAVQLIPELAE-RVAELTVYQRTPIWVVPKVDVRFPPAVRALFAR
MAB_4039c|M.abscessus_ATCC_199 IGTGATGVQLSGAIAD-DTASLVVFQRTPVYCIPKPDFRIPAIAQWALRI
TH_2450|M.thermoresistible__bu IGTGSSGAQIVSALSG-RVARLDVYQRTPNWILPRPDFALPRALQRVLEL
MLBr_00065|M.leprae_Br4923 IGSGATAVTLVPALANSGAKHVTMLQRSPTYIVSQPAKDKIAARLNRWLP
:*:*::.. : :: . : : **:* : ..:
Mb1428c|M.bovis_AF2122/97 P-GGKAVHR-LLSQAFVEATFPIAAHYFAVFP-------LAKHMESAGR-
Rv1393c|M.tuberculosis_H37Rv P-GGKAVHR-LLSQAFVEATFPIAAHYFAVFP-------LAKHMESAGR-
MMAR_2207|M.marinum_M P-GGKALQR-LLSQAYVEATFPISAHYFTVFP-------LARWSAVLGR-
MUL_1793|M.ulcerans_Agy99 P-GGKALQR-LLSQAYVEATFPISAHYFTVFP-------LARWSAVLGR-
MAV_3378|M.avium_104 P-GGKALQR-LLSQAYVELTFPISAHYFTVIP-------LAKRMAALGR-
Mvan_2671|M.vanbaalenii_PYR-1 P-FGKSLQR-LISQAFVELTFPLAAQYFTVNP-------MAKRMGAVGR-
Mflv_4607|M.gilvum_PYR-GCK APGAQIAAR-GASQAFVELTFPVAAHFHTAIP-------LASAIERAAI-
MSMEG_0816|M.smegmatis_MC2_155 VPLTQRVVR-AITDAIYAFMVDTAVLKHRYFRR------LNIAAADLGR-
MAB_4039c|M.abscessus_ATCC_199 PGLTAAIEWGALVGGSVGLWFLINTPGVVMRP-------LMRLFDRAGRA
TH_2450|M.thermoresistible__bu PGVAAVLHN--IGRAVFDLFFVVPIVHLMAHVPDRVLVRLLRGYDSLARF
MLBr_00065|M.leprae_Br4923 DKYAYTAVR--WKNILRQSALYGACQKWPQRMR-------NILLGHVAR-
. .
Mb1428c|M.bovis_AF2122/97 ---RYLRQQVHDPVVREQLTPRYAVGCKRPGFHN--TYLSTFNRDNVRLV
Rv1393c|M.tuberculosis_H37Rv ---RYLRQQVHDPVVREQLTPRYAVGCKRPGFHN--TYLSTFNRDNVRLV
MMAR_2207|M.marinum_M ---RYLRQRVNDPVVRDQLTPRYAVGCKRPGFHN--GYLSTFNRDNVQLV
MUL_1793|M.ulcerans_Agy99 ---RYLRQRVDDPVVRDQLTPRYAVDCKRPGFHN--GYLSTFNRDNVQLV
MAV_3378|M.avium_104 ---AYLRRQVRDPAVREQLTPRYAVGCKRPGFHN--GYLATFNRDNVRLV
Mvan_2671|M.vanbaalenii_PYR-1 ---AYLRKQVDDPVLRDKLTPRYAVGCKRPGFHN--TYLSTFNRDNVDLV
Mflv_4607|M.gilvum_PYR-GCK ---SYMRRQVTDPVVREKLTPRYALGCKRPSFHN--EYLKTFNRENVLLE
MSMEG_0816|M.smegmatis_MC2_155 ---LHLAASIRDPDLRSKLTPDYDFGCKRPTFSN--SYYRTFTKPHVHLQ
MAB_4039c|M.abscessus_ATCC_199 LYGAYLRAVVKDARVARDLLPSFGPLGNRPTLNS--AFPRVFNKPHCDLV
TH_2450|M.thermoresistible__bu AFRVLLRAVVHDPQTRRRLMPAHGILAKRPIISG--SYLPAFNDPRTHLI
MLBr_00065|M.leprae_Br4923 -------RLPKGYDVQKHFGPHYNPWEQRLCLVPDGDLFRAIRKGTVDMV
. : * . :* : .: :
Mb1428c|M.bovis_AF2122/97 TEPIDKITPTAVATTDGASHEIDVLVLATGFKVLDT----DSIPTYAVTG
Rv1393c|M.tuberculosis_H37Rv TEPIDKITPTAVATTDGASHEIDVLVLATGFKVLDT----DSIPTYAVTG
MMAR_2207|M.marinum_M TEPIEKITPTAVATDDGTDHEIDVLILATGFKVLDT----DDVLTYPVIG
MUL_1793|M.ulcerans_Agy99 TEPIEKITPTSVATDDGTDHEIDVLILATGFKVLDT----DDVLTYPVIG
MAV_3378|M.avium_104 TEPIDKITPDAVATTDGETHEIDVLILATGFKVMDP----DSVPTFAVTG
Mvan_2671|M.vanbaalenii_PYR-1 TEPIDKITGSGVSTTDGSLHEVDVLILATGFKVFAAHDGDDSVATFPVTG
Mflv_4607|M.gilvum_PYR-GCK TNPITRVDETAVITADGVRHEIDVLVLATGFKVMES----DSMPTYSLRG
MSMEG_0816|M.smegmatis_MC2_155 ADGIDHVEPDGIVNADGSKTVIDTLVLATGFDLWEA-----NFPAIEVIG
MAB_4039c|M.abscessus_ATCC_199 TTPIDEVVPEGVRTTDGTVYEADFLITATGFDLFSEP---ASYKRGRVIG
TH_2450|M.thermoresistible__bu TTPIERITAAGVRTTDGVERPVDLIVTATGYELWTDP---ETYFPGTILG
MLBr_00065|M.leprae_Br4923 TDAIDRFTSTGIRLKSGNELRADIIVTATGLNLQLFG------------G
: * .. .: .* * :: *** .: *
Mb1428c|M.bovis_AF2122/97 TGGASLSRFWDEHRLQAYEGVSVPGYPNFFTVFGPYGYVGSS-YFALIET
Rv1393c|M.tuberculosis_H37Rv TGGASLSRFWDEHRLQAYEGVSVPGYPNFFTVFGPYGYVGSS-YFALIET
MMAR_2207|M.marinum_M RAGRSLSQFWEEHRAQAYQGVSVPGYPNFFAVFGPYGYVGSS-YFALIET
MUL_1793|M.ulcerans_Agy99 RAGRSLSQFWEEHRAQAYQGVSVPGYRNFFAVFGPYGYVGSS-YFALIET
MAV_3378|M.avium_104 SGGRSLSRFWDEHRLQAYEGVTVPGFPNLFTVFGPYGYVGSS-YFALIEA
Mvan_2671|M.vanbaalenii_PYR-1 PGGRSLARFWDDNRLQAYEGVSVPGFPNFFTVFGPYGYVGSS-YFALIEA
Mflv_4607|M.gilvum_PYR-GCK VAGRDQAQWWDENRLQAYEGVSVPGFPNHFSVFGPYGYNGSS-YFALIEA
MSMEG_0816|M.smegmatis_MC2_155 RQGRDLGKWWRETRFQAYQGVSMPYFPNYLSLAGPYAFLGLN-FFNTMEY
MAB_4039c|M.abscessus_ATCC_199 AEGRDLGDFFNTHGMQAYESVSITGFPNRWIIVGPYSWTGNGGWHGLADT
TH_2450|M.thermoresistible__bu DAGFDLALDYRENGLRSYGGTAHPRLPNRWEIVGPLAFVGVG-WTDFVET
MLBr_00065|M.leprae_Br4923 AVATVDGQPVDLAQTMSYKGMMLSGLPNMIYTVG---YTNAS-WTLKADL
. . :* . . * * : . . : :
Mb1428c|M.bovis_AF2122/97 QAHHIIRCLKRARRTGATRIEVTEEANARYFAEVMRR-RHRQVFWQDSCR
Rv1393c|M.tuberculosis_H37Rv QAHHIIRCLKRARRTGATRIEVTEEANARYFAEVMRR-RHRQVFWQDSCR
MMAR_2207|M.marinum_M QTHHILRCLKRARRDGATRVEVTEEANARYFAEMMRR-RYRQVFWQDSCR
MUL_1793|M.ulcerans_Agy99 QTHHILRCLKRARRDGATRVEVTEEANARYFAEMMRR-RYRQVFWQDSCR
MAV_3378|M.avium_104 QTHHIVRCLKRAQRLGATRVEVSEEANDRYFAEMMRR-RHRQIFWQDSCR
Mvan_2671|M.vanbaalenii_PYR-1 QTRHIVRCLDAARRRRATRVEVRREANDRYFAEMMRK-RHRQIFWQDSCQ
Mflv_4607|M.gilvum_PYR-GCK QAGHILRCLRHARTADSNYVEVREEANQRFFAEMLAR-RHTQVFWQDSCA
MSMEG_0816|M.smegmatis_MC2_155 QMRLMERLLGEVARRDARTFEVTEEANRRYLDRMTDA-LGDSLFTLGNCA
MAB_4039c|M.abscessus_ATCC_199 AVTHIVRAISLARERHATRMEVRQEALDRFHQSMLRNGRNLKYYFTELNR
TH_2450|M.thermoresistible__bu MAEHAVRIIDAARRRGADVVTVTDEAFGRWDARMRKAGKAARLYYTRCNP
MLBr_00065|M.leprae_Br4923 VSEFFCRLLNYMNANDFDTVAVEYPGSDVEERPFMDFTPGYVLRSLDALP
* : . * . .
Mb1428c|M.bovis_AF2122/97 --LANSYYFDKNGDVP-LRPTTTVEAYWRSRRFDLGDYRISS--------
Rv1393c|M.tuberculosis_H37Rv --LANSYYFDKNGDVP-LRPTTTVEAYWRSRRFDLGDYRISS--------
MMAR_2207|M.marinum_M --RANSYYFDKNGDVP-LRPTTTVEAYWRGRHFDLDNYRFGR--------
MUL_1793|M.ulcerans_Agy99 --RANSYYFDKNGDVP-LRPTTTVEAYWRGRHFDLDDYRFGR--------
MAV_3378|M.avium_104 --LANSYYFDKNGDVP-LRPGTTPEVYWRSRRFDLDDYRFTG--------
Mvan_2671|M.vanbaalenii_PYR-1 --LSNSYYFDQHGDVP-LRPASTPEAYWRSRRFPIDDYEFSC--------
Mflv_4607|M.gilvum_PYR-GCK --GANSYYFDKHGDVP-LRPTTTVESIWRSRRFDLADYRFERRPAKKADT
MSMEG_0816|M.smegmatis_MC2_155 --SARSYYFNPSGEATLLRPMTTRRAVAEASRFPLSDYTFA---------
MAB_4039c|M.abscessus_ATCC_199 --GVRSYWKNADDDVPLLRPTTTLQARRAARNFPAMDYVYEQHATNSTAA
TH_2450|M.thermoresistible__bu --GVNTYYVNSQRDTVYHRPQTITESLVFAHRPPLTDYRFERRPAAARSA
MLBr_00065|M.leprae_Br4923 KQGSRTPWRLNQNYLRDIRLIRRGKVADEGLLFAKKTTPVTV--------
.: : * . .
Mb1428c|M.bovis_AF2122/97 -------------
Rv1393c|M.tuberculosis_H37Rv -------------
MMAR_2207|M.marinum_M -------------
MUL_1793|M.ulcerans_Agy99 -------------
MAV_3378|M.avium_104 -------------
Mvan_2671|M.vanbaalenii_PYR-1 -------------
Mflv_4607|M.gilvum_PYR-GCK APQKVDTAG----
MSMEG_0816|M.smegmatis_MC2_155 -------------
MAB_4039c|M.abscessus_ATCC_199 VVHSQATV-----
TH_2450|M.thermoresistible__bu VRALRHAEGNEAV
MLBr_00065|M.leprae_Br4923 -------------