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SSEQPEFEVAVIGAGPGGIAAGVKLLQAGVGNIVLLERADDVGGSWHENHYPGLGVDVPSFAYQYSFARN PQWSRLFPKGAEVKQYHVDVAKRFGVYERVRFNTNVEREEWDDEAGHWKLHTSDGTVVTTRFLVSAVGAF VRPKADIGIAGAHSFGGKIQRPTDWDHEFDMAGKSVGIIGTGASAVQIIPTIAPEIAHLTVFQRTPVWSL PKPDLTLGPFLRPLYAAPGVQSALNGAVLVLADVLLRSLSKAPFRWSRPVMDRFDAACIAAYRRYIRWVV DDPATAEKLTPNFGPLAKRPTISNGYLKAYNRNNVTLVTEPIERITKKGVRTRDGVEHRFNVLILATGYE VFSDPETYRPGAILGRNGFDLASYYGENGLQAYESVAVHGLPNRWTLCGPYSWTGSGWHAFMEMTSDHAV RAILETNRRGADRCEVRKEVADAYHHTVKQRSEAMRYYLAELNGHVPTYYRNSQGDSTYLRPAGFFEARR STRDFPLADYVYEKHPAKVTA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_0142c | - | - | 100% (512) | putative monooxygenase |
| M. abscessus ATCC 19977 | MAB_4039c | - | e-132 | 44.64% (513) | monooxygenase |
| M. abscessus ATCC 19977 | MAB_4017c | - | e-122 | 43.54% (503) | monooxygenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1428c | - | 1e-100 | 40.24% (502) | monoxygenase |
| M. gilvum PYR-GCK | Mflv_4607 | - | 1e-102 | 40.47% (509) | cyclohexanone monooxygenase |
| M. tuberculosis H37Rv | Rv1393c | - | 1e-100 | 40.24% (502) | monoxygenase |
| M. leprae Br4923 | MLBr_00065 | - | 9e-26 | 24.08% (461) | putative monooxygenase |
| M. marinum M | MMAR_2207 | - | 1e-102 | 40.92% (501) | monoxygenase |
| M. avium 104 | MAV_3378 | - | 3e-99 | 41.04% (502) | lipolytic enzyme |
| M. smegmatis MC2 155 | MSMEG_0816 | - | 1e-82 | 34.00% (497) | flavin-binding monooxygenase |
| M. thermoresistible (build 8) | TH_2450 | - | 1e-119 | 43.42% (509) | PUTATIVE putative FAD dependent oxidoreductase |
| M. ulcerans Agy99 | MUL_1793 | - | 4e-99 | 41.26% (492) | monoxygenase |
| M. vanbaalenii PYR-1 | Mvan_2671 | - | 4e-95 | 40.00% (505) | cyclohexanone monooxygenase |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_0142c|M.abscessus_ATCC_199 -------------MSSE---QPEFEVAVIGAGPGGIAAGVKLLQAGVG-N
TH_2450|M.thermoresistible__bu -------------MTVTGDVRPEYDVAIIGAGPGGIAAAHKLRRRGIT-D
Mb1428c|M.bovis_AF2122/97 -------------------MMPDYHALIVGAGFSGIGAAIKLDRAGFS-D
Rv1393c|M.tuberculosis_H37Rv -------------------MMPDYHALIVGAGFSGIGAAIKLDRAGFS-D
MMAR_2207|M.marinum_M -----------------MSIEPDYQIVIVGAGFSGIGAAISLDKAGFG-D
MUL_1793|M.ulcerans_Agy99 --------------------------MIVGAGFSGIGAAISLDKAGFG-D
MAV_3378|M.avium_104 ---------------MSSPAVPDHHTLIIGAGFSGIGAAIKLDKAGLP-D
Mvan_2671|M.vanbaalenii_PYR-1 --------------------MHDVETVIVGAGFSGIGAAIGLDRVGMS-D
Mflv_4607|M.gilvum_PYR-GCK MSVHVAGDENAPTSGAPTYEVPTHEILVIGAGFSGIGVGIKLLKEGFS-D
MSMEG_0816|M.smegmatis_MC2_155 ------------------MRPVVHDAVIVGAGFAGLGAAIQLKKMSFD-D
MLBr_00065|M.leprae_Br4923 --------------MVVMAETEYLDVVIVGAGISGVSAAWHLQDRCPNKS
::*** .*:... * .
MAB_0142c|M.abscessus_ATCC_199 IVLLERADDVGGSWHENHYPGLGVDVPSFAYQYSFARNPQWSRLFPKGAE
TH_2450|M.thermoresistible__bu IAILERGDDFGGTWRDNHYPGLAVDIPILWYQFSFNRNPRWSRVFAPGPE
Mb1428c|M.bovis_AF2122/97 YLVVEAGDGVGGTWHWNTYPGIAVDIPSFSYQFSFEQSRHWSRTYAPGHE
Rv1393c|M.tuberculosis_H37Rv YLVVEAGDGVGGTWHWNTYPGIAVDIPSFSYQFSFEQSRHWSRTYAPGHE
MMAR_2207|M.marinum_M YLVIEAGDGVGGTWFWNTYPGIAVDIPSFSYQFSFEQSPDWSRSYAPGRE
MUL_1793|M.ulcerans_Agy99 YLVIEAGDAVGGTWFWNTYPGIAVDIPSFSYQFSFEQSPDWSRSYAPGRE
MAV_3378|M.avium_104 YRVIEAGDGVGGTWHWNTYPGIAVDIPSFSYQFSFEQSRHWSRTYAPGRE
Mvan_2671|M.vanbaalenii_PYR-1 YVVVEAGDEPGGTWYWNTYPGIAVDIPSFSYQFSFEQSSAWSRTYAHGHE
Mflv_4607|M.gilvum_PYR-GCK FLIVDEAQGVGGTWYWNTYPGIAVDIPSYSYQFSFEKRPSWSRTYAPGIE
MSMEG_0816|M.smegmatis_MC2_155 FVILEREDDLGGTWYVNHYPGLAVDVPTTTYSYFFEPNPSWSRLFSTGRE
MLBr_00065|M.leprae_Br4923 YVILEKRAGMGGTWDLFRYPGIRSDSDMYTLGFRFRP-WTKCQAIADGKP
::: **:* ***: * : * .: . *
MAB_0142c|M.abscessus_ATCC_199 VKQYHVDVAKRFGVYERVRFNTNVEREEWDDEAGHWKLHTSDGT---VVT
TH_2450|M.thermoresistible__bu IHRYLTDTARSLGLYPLLRPHHDVVGQRWNAENAMWQLTVRDRP---PVT
Mb1428c|M.bovis_AF2122/97 LKAYAEHCVDKYGIRSRIRLNTKVLAAEFDDEHSLWRVQTDPGG---EIT
Rv1393c|M.tuberculosis_H37Rv LKAYAEHCVDKYGIRSRIRLNTKVLAAEFDDEHSLWRVQTDPGG---EIT
MMAR_2207|M.marinum_M LRAYAEHCADKYGIRPRIRFNTKVLGAEFDDERSLWRLQTDPGG---ELT
MUL_1793|M.ulcerans_Agy99 LRAYAEHCADKYGIRPRIRFNTKVLGAELDDERSLWRLQTDPGG---DLI
MAV_3378|M.avium_104 LKAYAEHCADKYGIRSRIRFNTKVLAAEFDDEQRLWRVQTDPGG---EVT
Mvan_2671|M.vanbaalenii_PYR-1 LKTYAEHCVDKYGLRPRIRFATTVRSADFDEAQGIWRLALDTADGPATLS
Mflv_4607|M.gilvum_PYR-GCK LKNYAKHCVKKYGLASRIRFGVTVVRAEFDEESTLWRLFTSTDE---ELT
MSMEG_0816|M.smegmatis_MC2_155 IKRYADDVADKYDVRRHIRFGTTVTGARWDEDDNVWQVSLTDGE---QLQ
MLBr_00065|M.leprae_Br4923 ILEYIKSTAVMHGIDKYIRLNHKVTGADWSSIENRWTVQVENNGTPRMIS
: * . .: :* * . * : :
MAB_0142c|M.abscessus_ATCC_199 TRFLVSAVGAFVRPK-ADIGIAGAHSFGGKIQRPTDWDHEFDMAGKSVGI
TH_2450|M.thermoresistible__bu ARFVISSVGGYVNAR-ATD-LEGLSDFTGKVLRPNCWDDGYDTRDKRVAV
Mb1428c|M.bovis_AF2122/97 ARFLISACGILTVPK-LPD-IDGVDSFEGVTMHTARWDHTQDLTGKRVGI
Rv1393c|M.tuberculosis_H37Rv ARFLISACGILTVPK-LPD-IDGVDSFEGVTMHTARWDHTQDLTGKRVGI
MMAR_2207|M.marinum_M TRFIINASGVLTVPK-LPD-IAGVDSFAGVTMHTARWDHSQELTGKRVGI
MUL_1793|M.ulcerans_Agy99 TRFIINASGVLTVPK-LPD-IAGVDSFAGVTMHTARWDHSQELTGKRVGI
MAV_3378|M.avium_104 ARFLISACGVLTVPN-LPD-IDGVDSFAGITMHTARWDHGQDLRGKRVAV
Mvan_2671|M.vanbaalenii_PYR-1 ARFLVNAGGVLTVPK-LPD-IAGVDSFAGVTMHTARWDHTQDLRGKRVAI
Mflv_4607|M.gilvum_PYR-GCK ARFVINASGVLTRPK-SPD-IPGVGDFGGVTMHTSRWDHQQTLTGKRVAV
MSMEG_0816|M.smegmatis_MC2_155 ARFLITATGFLSQPH-TPD-IPGITEFDGKVIHTTDWDDGCSLYGRRAAV
MLBr_00065|M.leprae_Br4923 CSFLFLCSGYYNYEQGYAPTFLGSEDFTGPIIHPQHWPEDLDYAAKNIVV
*:. . * . : * .* * :. * . : :
MAB_0142c|M.abscessus_ATCC_199 IGTGASAVQIIPTIAP-EIAHLTVFQRTPVWSLPKPDLTLGPFLRPLYAA
TH_2450|M.thermoresistible__bu IGTGSSGAQIVSALSG-RVARLDVYQRTPNWILPRPDFALPRALQRVLEL
Mb1428c|M.bovis_AF2122/97 IGTGASAVQVIPEMAP-IVSHLTVFQRTPIWCFPKFDVPLPTAVRWAMRI
Rv1393c|M.tuberculosis_H37Rv IGTGASAVQVIPEMAP-IVSHLTVFQRTPIWCFPKFDVPLPTAVRWAMRI
MMAR_2207|M.marinum_M IGTGASAVQVIPEIAP-IVKHLTVFQRTPIWCFPKFDFPLPAALRWAMRI
MUL_1793|M.ulcerans_Agy99 IGTGASAVQVIPEIAP-IVKHLTVFQRTPIWCFPKFDFPLPAALRWAMRI
MAV_3378|M.avium_104 IGTGASAVQVIPEIAP-IVSSLTVFQRTPIWCFPKLDVPLPAPARWAMRF
Mvan_2671|M.vanbaalenii_PYR-1 IGTGASAVQVIPEIAP-IVERLTVFQRTPIWCFPKFDVPLSKTAQTMMRL
Mflv_4607|M.gilvum_PYR-GCK IGTGASAVQLIPSIAK-DVDTLTVFQRTPIWCLPKFDFAVPRPLSALLRL
MSMEG_0816|M.smegmatis_MC2_155 VGTGATAVQLIPELAE-RVAELTVYQRTPIWVVPKVDVRFPPAVRALFAR
MLBr_00065|M.leprae_Br4923 IGSGATAVTLVPALANSGAKHVTMLQRSPTYIVSQPAKDKIAARLNRWLP
:*:*::.. ::. :: : : **:* : ..:
MAB_0142c|M.abscessus_ATCC_199 P-GVQSALNGAVLVLADVLLRS-----LSKAPFRWSRPVMDRFDAACIAA
TH_2450|M.thermoresistible__bu P-GVAAVLHNIGRAVFDLFFVVPIVHLMAHVPDRVLVRLLRGYDSLARFA
Mb1428c|M.bovis_AF2122/97 P-GGKAVHRLLSQAFVEATFPIA----------AHYFAVFP-LAKHMESA
Rv1393c|M.tuberculosis_H37Rv P-GGKAVHRLLSQAFVEATFPIA----------AHYFAVFP-LAKHMESA
MMAR_2207|M.marinum_M P-GGKALQRLLSQAYVEATFPIS----------AHYFTVFP-LARWSAVL
MUL_1793|M.ulcerans_Agy99 P-GGKALQRLLSQAYVEATFPIS----------AHYFTVFP-LARWSAVL
MAV_3378|M.avium_104 P-GGKALQRLLSQAYVELTFPIS----------AHYFTVIP-LAKRMAAL
Mvan_2671|M.vanbaalenii_PYR-1 P-FGKSLQRLISQAFVELTFPLA----------AQYFTVNP-MAKRMGAV
Mflv_4607|M.gilvum_PYR-GCK APGAQIAARGASQAFVELTFPVA----------AHFHTAIP-LASAIERA
MSMEG_0816|M.smegmatis_MC2_155 VPLTQRVVRAITDAIYAFMVDTA----------VLKHRYFRRLNIAAADL
MLBr_00065|M.leprae_Br4923 DKYAYTAVRWKNILRQSALYGAC----------QKWPQRMR--NILLGHV
.
MAB_0142c|M.abscessus_ATCC_199 YRRYIRWVVDDPATAEKLTPNFGPLAKRPTISNGYLKAYNRNNVTLVTEP
TH_2450|M.thermoresistible__bu FRVLLRAVVHDPQTRRRLMPAHGILAKRPIISGSYLPAFNDPRTHLITTP
Mb1428c|M.bovis_AF2122/97 GRRYLRQQVHDPVVREQLTPRYAVGCKRPGFHNTYLSTFNRDNVRLVTEP
Rv1393c|M.tuberculosis_H37Rv GRRYLRQQVHDPVVREQLTPRYAVGCKRPGFHNTYLSTFNRDNVRLVTEP
MMAR_2207|M.marinum_M GRRYLRQRVNDPVVRDQLTPRYAVGCKRPGFHNGYLSTFNRDNVQLVTEP
MUL_1793|M.ulcerans_Agy99 GRRYLRQRVDDPVVRDQLTPRYAVDCKRPGFHNGYLSTFNRDNVQLVTEP
MAV_3378|M.avium_104 GRAYLRRQVRDPAVREQLTPRYAVGCKRPGFHNGYLATFNRDNVRLVTEP
Mvan_2671|M.vanbaalenii_PYR-1 GRAYLRKQVDDPVLRDKLTPRYAVGCKRPGFHNTYLSTFNRDNVDLVTEP
Mflv_4607|M.gilvum_PYR-GCK AISYMRRQVTDPVVREKLTPRYALGCKRPSFHNEYLKTFNRENVLLETNP
MSMEG_0816|M.smegmatis_MC2_155 GRLHLAASIRDPDLRSKLTPDYDFGCKRPTFSNSYYRTFTKPHVHLQADG
MLBr_00065|M.leprae_Br4923 ARRLPKGYDVQKHFGPHYNPWEQRLCLVP--DGDLFRAIRKGTVDMVTDA
: : * . * . : . : :
MAB_0142c|M.abscessus_ATCC_199 IERITKKGVRTRDGVEHRFNVLILATGYEVFSD---PETYRPGAILGRNG
TH_2450|M.thermoresistible__bu IERITAAGVRTTDGVERPVDLIVTATGYELWTD---PETYFPGTILGDAG
Mb1428c|M.bovis_AF2122/97 IDKITPTAVATTDGASHEIDVLVLATGFKVLDT----DSIPTYAVTGTGG
Rv1393c|M.tuberculosis_H37Rv IDKITPTAVATTDGASHEIDVLVLATGFKVLDT----DSIPTYAVTGTGG
MMAR_2207|M.marinum_M IEKITPTAVATDDGTDHEIDVLILATGFKVLDT----DDVLTYPVIGRAG
MUL_1793|M.ulcerans_Agy99 IEKITPTSVATDDGTDHEIDVLILATGFKVLDT----DDVLTYPVIGRAG
MAV_3378|M.avium_104 IDKITPDAVATTDGETHEIDVLILATGFKVMDP----DSVPTFAVTGSGG
Mvan_2671|M.vanbaalenii_PYR-1 IDKITGSGVSTTDGSLHEVDVLILATGFKVFAAHDGDDSVATFPVTGPGG
Mflv_4607|M.gilvum_PYR-GCK ITRVDETAVITADGVRHEIDVLVLATGFKVMES----DSMPTYSLRGVAG
MSMEG_0816|M.smegmatis_MC2_155 IDHVEPDGIVNADGSKTVIDTLVLATGFDLWEA-----NFPAIEVIGRQG
MLBr_00065|M.leprae_Br4923 IDRFTSTGIRLKSGNELRADIIVTATGLNLQLFG------------GAVA
* :. .: .* : :: *** .: * .
MAB_0142c|M.abscessus_ATCC_199 FDLASYYGENGLQAYESVAVHGLPNRWTLCGPYSWTGSGWHAFMEMTSDH
TH_2450|M.thermoresistible__bu FDLALDYRENGLRSYGGTAHPRLPNRWEIVGPLAFVGVGWTDFVETMAEH
Mb1428c|M.bovis_AF2122/97 ASLSRFWDEHRLQAYEGVSVPGYPNFFTVFGPYGYVGSSYFALIETQAHH
Rv1393c|M.tuberculosis_H37Rv ASLSRFWDEHRLQAYEGVSVPGYPNFFTVFGPYGYVGSSYFALIETQAHH
MMAR_2207|M.marinum_M RSLSQFWEEHRAQAYQGVSVPGYPNFFAVFGPYGYVGSSYFALIETQTHH
MUL_1793|M.ulcerans_Agy99 RSLSQFWEEHRAQAYQGVSVPGYRNFFAVFGPYGYVGSSYFALIETQTHH
MAV_3378|M.avium_104 RSLSRFWDEHRLQAYEGVTVPGFPNLFTVFGPYGYVGSSYFALIEAQTHH
Mvan_2671|M.vanbaalenii_PYR-1 RSLARFWDDNRLQAYEGVSVPGFPNFFTVFGPYGYVGSSYFALIEAQTRH
Mflv_4607|M.gilvum_PYR-GCK RDQAQWWDENRLQAYEGVSVPGFPNHFSVFGPYGYNGSSYFALIEAQAGH
MSMEG_0816|M.smegmatis_MC2_155 RDLGKWWRETRFQAYQGVSMPYFPNYLSLAGPYAFLGLNFFNTMEYQMRL
MLBr_00065|M.leprae_Br4923 TVDGQPVDLAQTMSYKGMMLSGLPNMIYTVG---YTNASWTLKADLVSEF
. :* . * * : . .: :
MAB_0142c|M.abscessus_ATCC_199 AVRAILETNRRGADRCEVRKEVADAYHHTVKQRSEAMRYYLAELNG--HV
TH_2450|M.thermoresistible__bu AVRIIDAARRRGADVVTVTDEAFGRWDARMRKAGKAARLYYTRCNP--GV
Mb1428c|M.bovis_AF2122/97 IIRCLKRARRTGATRIEVTEEANARYFAEVMRRRHRQVFWQDSCR---LA
Rv1393c|M.tuberculosis_H37Rv IIRCLKRARRTGATRIEVTEEANARYFAEVMRRRHRQVFWQDSCR---LA
MMAR_2207|M.marinum_M ILRCLKRARRDGATRVEVTEEANARYFAEMMRRRYRQVFWQDSCR---RA
MUL_1793|M.ulcerans_Agy99 ILRCLKRARRDGATRVEVTEEANARYFAEMMRRRYRQVFWQDSCR---RA
MAV_3378|M.avium_104 IVRCLKRAQRLGATRVEVSEEANDRYFAEMMRRRHRQIFWQDSCR---LA
Mvan_2671|M.vanbaalenii_PYR-1 IVRCLDAARRRRATRVEVRREANDRYFAEMMRKRHRQIFWQDSCQ---LS
Mflv_4607|M.gilvum_PYR-GCK ILRCLRHARTADSNYVEVREEANQRFFAEMLARRHTQVFWQDSCA---GA
MSMEG_0816|M.smegmatis_MC2_155 MERLLGEVARRDARTFEVTEEANRRYLDRMTDALGDSLFTLGNCA---SA
MLBr_00065|M.leprae_Br4923 FCRLLNYMNANDFDTVAVEYPGSDVEERPFMDFTPGYVLRSLDALPKQGS
* : * .
MAB_0142c|M.abscessus_ATCC_199 PTYYRNSQGDSTYLRPAGFFEARRSTRDFPLADYVYEKHPAKVTA-----
TH_2450|M.thermoresistible__bu NTYYVNSQRDTVYHRPQTITESLVFAHRPPLTDYRFERRPAAARSAVRAL
Mb1428c|M.bovis_AF2122/97 NSYYFDKNGDVP-LRPTTTVEAYWRSRRFDLGDYRISS------------
Rv1393c|M.tuberculosis_H37Rv NSYYFDKNGDVP-LRPTTTVEAYWRSRRFDLGDYRISS------------
MMAR_2207|M.marinum_M NSYYFDKNGDVP-LRPTTTVEAYWRGRHFDLDNYRFGR------------
MUL_1793|M.ulcerans_Agy99 NSYYFDKNGDVP-LRPTTTVEAYWRGRHFDLDDYRFGR------------
MAV_3378|M.avium_104 NSYYFDKNGDVP-LRPGTTPEVYWRSRRFDLDDYRFTG------------
Mvan_2671|M.vanbaalenii_PYR-1 NSYYFDQHGDVP-LRPASTPEAYWRSRRFPIDDYEFSC------------
Mflv_4607|M.gilvum_PYR-GCK NSYYFDKHGDVP-LRPTTTVESIWRSRRFDLADYRFERRPAKKADTAPQK
MSMEG_0816|M.smegmatis_MC2_155 RSYYFNPSGEATLLRPMTTRRAVAEASRFPLSDYTFA-------------
MLBr_00065|M.leprae_Br4923 RTPWRLNQNYLRDIRLIRRGKVADEGLLFAKKTTPVTV------------
: : * .
MAB_0142c|M.abscessus_ATCC_199 ---------
TH_2450|M.thermoresistible__bu RHAEGNEAV
Mb1428c|M.bovis_AF2122/97 ---------
Rv1393c|M.tuberculosis_H37Rv ---------
MMAR_2207|M.marinum_M ---------
MUL_1793|M.ulcerans_Agy99 ---------
MAV_3378|M.avium_104 ---------
Mvan_2671|M.vanbaalenii_PYR-1 ---------
Mflv_4607|M.gilvum_PYR-GCK VDTAG----
MSMEG_0816|M.smegmatis_MC2_155 ---------
MLBr_00065|M.leprae_Br4923 ---------