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GLPDEPDYEVAIIGAGLGGICAAIKLLEIGIKDFVIIDRDEDFGGTWLRNTYPGVGADIPVVAYQFTFAP KGDWQRFFASGAEIQQYALDLVAEHGLRAHARFGTCVQREVFDEDNHSWRLHTTGGEVISSRFLISAIGA YINPRTAPDIPGLDTFAGPVQVPSRWQHDVDMRGKRVGIVGVGSSTVQIAPAIAGEVEHLDVYQRTPQWY FPKPDFRLPRPLQRLLSRRRFANALNGIALAGIELGLRVLIYTPKPLFRAGGAIFDRVALWAYLGWLRYK VKDPEVRQQLRPRFGAGCTRGTLGADYLPTFNRANVTLVSNGIERITPTGIVDRAGTERPIDVLVLATGY EMFSDPETYRVGTVLGTKGFDLAEFYRDNGLQAYQSTSVPGLPNRFMLVGPYSWTGTSFHYILENSMRHI EAVLKLARARRATWVEVTQEALDDFQASISRSGANLNRYFTVNCAGSNSYFINSQGDTPYVRPWTVLQSY RRSVQFPSTAYEFKRISSPVKEIEHAV*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4017c | - | - | 100% (518) | monooxygenase |
| M. abscessus ATCC 19977 | MAB_0142c | - | e-122 | 43.54% (503) | putative monooxygenase |
| M. abscessus ATCC 19977 | MAB_4042c | - | e-117 | 42.97% (505) | monooxygenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1428c | - | 1e-97 | 40.59% (505) | monoxygenase |
| M. gilvum PYR-GCK | Mflv_4607 | - | 1e-103 | 40.27% (514) | cyclohexanone monooxygenase |
| M. tuberculosis H37Rv | Rv1393c | - | 1e-97 | 40.59% (505) | monoxygenase |
| M. leprae Br4923 | MLBr_00065 | - | 2e-27 | 27.55% (421) | putative monooxygenase |
| M. marinum M | MMAR_2207 | - | 1e-102 | 40.81% (517) | monoxygenase |
| M. avium 104 | MAV_3378 | - | 7e-98 | 39.53% (516) | lipolytic enzyme |
| M. smegmatis MC2 155 | MSMEG_0816 | - | 2e-88 | 35.91% (504) | flavin-binding monooxygenase |
| M. thermoresistible (build 8) | TH_2450 | - | 1e-107 | 41.15% (520) | PUTATIVE putative FAD dependent oxidoreductase |
| M. ulcerans Agy99 | MUL_1793 | - | 2e-95 | 40.00% (510) | monoxygenase |
| M. vanbaalenii PYR-1 | Mvan_2671 | - | 4e-99 | 40.71% (506) | cyclohexanone monooxygenase |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_4017c|M.abscessus_ATCC_199 -------------MGLPDE--PDYEVAIIGAGLGGICAAIKLLEIG-IKD
TH_2450|M.thermoresistible__bu -------------MTVTGDVRPEYDVAIIGAGPGGIAAAHKLRRRG-ITD
Mb1428c|M.bovis_AF2122/97 -------------------MMPDYHALIVGAGFSGIGAAIKLDRAG-FSD
Rv1393c|M.tuberculosis_H37Rv -------------------MMPDYHALIVGAGFSGIGAAIKLDRAG-FSD
MMAR_2207|M.marinum_M -----------------MSIEPDYQIVIVGAGFSGIGAAISLDKAG-FGD
MUL_1793|M.ulcerans_Agy99 --------------------------MIVGAGFSGIGAAISLDKAG-FGD
MAV_3378|M.avium_104 ---------------MSSPAVPDHHTLIIGAGFSGIGAAIKLDKAG-LPD
Mvan_2671|M.vanbaalenii_PYR-1 --------------------MHDVETVIVGAGFSGIGAAIGLDRVG-MSD
Mflv_4607|M.gilvum_PYR-GCK MSVHVAGDENAPTSGAPTYEVPTHEILVIGAGFSGIGVGIKLLKEG-FSD
MSMEG_0816|M.smegmatis_MC2_155 ------------------MRPVVHDAVIVGAGFAGLGAAIQLKKMS-FDD
MLBr_00065|M.leprae_Br4923 --------------MVVMAETEYLDVVIVGAGISGVSAAWHLQDRCPNKS
::*** .*: .. * .
MAB_4017c|M.abscessus_ATCC_199 FVIIDRDEDFGGTWLRNTYPGVGADIPVVAYQFTFAPKGDWQRFFASGAE
TH_2450|M.thermoresistible__bu IAILERGDDFGGTWRDNHYPGLAVDIPILWYQFSFNRNPRWSRVFAPGPE
Mb1428c|M.bovis_AF2122/97 YLVVEAGDGVGGTWHWNTYPGIAVDIPSFSYQFSFEQSRHWSRTYAPGHE
Rv1393c|M.tuberculosis_H37Rv YLVVEAGDGVGGTWHWNTYPGIAVDIPSFSYQFSFEQSRHWSRTYAPGHE
MMAR_2207|M.marinum_M YLVIEAGDGVGGTWFWNTYPGIAVDIPSFSYQFSFEQSPDWSRSYAPGRE
MUL_1793|M.ulcerans_Agy99 YLVIEAGDAVGGTWFWNTYPGIAVDIPSFSYQFSFEQSPDWSRSYAPGRE
MAV_3378|M.avium_104 YRVIEAGDGVGGTWHWNTYPGIAVDIPSFSYQFSFEQSRHWSRTYAPGRE
Mvan_2671|M.vanbaalenii_PYR-1 YVVVEAGDEPGGTWYWNTYPGIAVDIPSFSYQFSFEQSSAWSRTYAHGHE
Mflv_4607|M.gilvum_PYR-GCK FLIVDEAQGVGGTWYWNTYPGIAVDIPSYSYQFSFEKRPSWSRTYAPGIE
MSMEG_0816|M.smegmatis_MC2_155 FVILEREDDLGGTWYVNHYPGLAVDVPTTTYSYFFEPNPSWSRLFSTGRE
MLBr_00065|M.leprae_Br4923 YVILEKRAGMGGTWDLFRYPGIRSDSDMYTLGFRFRP-WTKCQAIADGKP
::: **** ***: * : * : : *
MAB_4017c|M.abscessus_ATCC_199 IQQYALDLVAEHGLRAHARFGTCVQREVFDEDNHSWRLHTTGGE---VIS
TH_2450|M.thermoresistible__bu IHRYLTDTARSLGLYPLLRPHHDVVGQRWNAENAMWQLTVRDRP---PVT
Mb1428c|M.bovis_AF2122/97 LKAYAEHCVDKYGIRSRIRLNTKVLAAEFDDEHSLWRVQTDPGG---EIT
Rv1393c|M.tuberculosis_H37Rv LKAYAEHCVDKYGIRSRIRLNTKVLAAEFDDEHSLWRVQTDPGG---EIT
MMAR_2207|M.marinum_M LRAYAEHCADKYGIRPRIRFNTKVLGAEFDDERSLWRLQTDPGG---ELT
MUL_1793|M.ulcerans_Agy99 LRAYAEHCADKYGIRPRIRFNTKVLGAELDDERSLWRLQTDPGG---DLI
MAV_3378|M.avium_104 LKAYAEHCADKYGIRSRIRFNTKVLAAEFDDEQRLWRVQTDPGG---EVT
Mvan_2671|M.vanbaalenii_PYR-1 LKTYAEHCVDKYGLRPRIRFATTVRSADFDEAQGIWRLALDTADGPATLS
Mflv_4607|M.gilvum_PYR-GCK LKNYAKHCVKKYGLASRIRFGVTVVRAEFDEESTLWRLFTSTDE---ELT
MSMEG_0816|M.smegmatis_MC2_155 IKRYADDVADKYDVRRHIRFGTTVTGARWDEDDNVWQVSLTDGE---QLQ
MLBr_00065|M.leprae_Br4923 ILEYIKSTAVMHGIDKYIRLNHKVTGADWSSIENRWTVQVENNGTPRMIS
: * . .: * * . * : :
MAB_4017c|M.abscessus_ATCC_199 SRFLISAIGAYINPRT-APDIPGLDTFAGPVQVPSRWQHDVDMRGKRVGI
TH_2450|M.thermoresistible__bu ARFVISSVGGYVNAR--ATDLEGLSDFTGKVLRPNCWDDGYDTRDKRVAV
Mb1428c|M.bovis_AF2122/97 ARFLISACGILTVPK--LPDIDGVDSFEGVTMHTARWDHTQDLTGKRVGI
Rv1393c|M.tuberculosis_H37Rv ARFLISACGILTVPK--LPDIDGVDSFEGVTMHTARWDHTQDLTGKRVGI
MMAR_2207|M.marinum_M TRFIINASGVLTVPK--LPDIAGVDSFAGVTMHTARWDHSQELTGKRVGI
MUL_1793|M.ulcerans_Agy99 TRFIINASGVLTVPK--LPDIAGVDSFAGVTMHTARWDHSQELTGKRVGI
MAV_3378|M.avium_104 ARFLISACGVLTVPN--LPDIDGVDSFAGITMHTARWDHGQDLRGKRVAV
Mvan_2671|M.vanbaalenii_PYR-1 ARFLVNAGGVLTVPK--LPDIAGVDSFAGVTMHTARWDHTQDLRGKRVAI
Mflv_4607|M.gilvum_PYR-GCK ARFVINASGVLTRPK--SPDIPGVGDFGGVTMHTSRWDHQQTLTGKRVAV
MSMEG_0816|M.smegmatis_MC2_155 ARFLITATGFLSQPH--TPDIPGITEFDGKVIHTTDWDDGCSLYGRRAAV
MLBr_00065|M.leprae_Br4923 CSFLFLCSGYYNYEQGYAPTFLGSEDFTGPIIHPQHWPEDLDYAAKNIVV
*:. . * . . : * * * . * . :. :
MAB_4017c|M.abscessus_ATCC_199 VGVGSSTVQIAPAIAG-EVEHLDVYQRTPQWYFPKPDFRLPRPLQRLLSR
TH_2450|M.thermoresistible__bu IGTGSSGAQIVSALSG-RVARLDVYQRTPNWILPRPDFALPRALQRVLEL
Mb1428c|M.bovis_AF2122/97 IGTGASAVQVIPEMAP-IVSHLTVFQRTPIWCFPKFDVPLPTAVRWAMRI
Rv1393c|M.tuberculosis_H37Rv IGTGASAVQVIPEMAP-IVSHLTVFQRTPIWCFPKFDVPLPTAVRWAMRI
MMAR_2207|M.marinum_M IGTGASAVQVIPEIAP-IVKHLTVFQRTPIWCFPKFDFPLPAALRWAMRI
MUL_1793|M.ulcerans_Agy99 IGTGASAVQVIPEIAP-IVKHLTVFQRTPIWCFPKFDFPLPAALRWAMRI
MAV_3378|M.avium_104 IGTGASAVQVIPEIAP-IVSSLTVFQRTPIWCFPKLDVPLPAPARWAMRF
Mvan_2671|M.vanbaalenii_PYR-1 IGTGASAVQVIPEIAP-IVERLTVFQRTPIWCFPKFDVPLSKTAQTMMRL
Mflv_4607|M.gilvum_PYR-GCK IGTGASAVQLIPSIAK-DVDTLTVFQRTPIWCLPKFDFAVPRPLSALLRL
MSMEG_0816|M.smegmatis_MC2_155 VGTGATAVQLIPELAE-RVAELTVYQRTPIWVVPKVDVRFPPAVRALFAR
MLBr_00065|M.leprae_Br4923 IGSGATAVTLVPALANSGAKHVTMLQRSPTYIVSQPAKDKIAARLNRWLP
:* *:: . : . :: . : : **:* : ..: .
MAB_4017c|M.abscessus_ATCC_199 R-RFANALNGIALAGIELG-----LRVLIYTPKPLFRAGGAIFDRVALWA
TH_2450|M.thermoresistible__bu P-GVAAVLHNIGRAVFDLFFVVPIVHLMAHVPDRVLVRLLRGYDSLARFA
Mb1428c|M.bovis_AF2122/97 P-GGKAVHRLLSQAFVEATFP---IAAHYFAVFP-LAKHMESAG------
Rv1393c|M.tuberculosis_H37Rv P-GGKAVHRLLSQAFVEATFP---IAAHYFAVFP-LAKHMESAG------
MMAR_2207|M.marinum_M P-GGKALQRLLSQAYVEATFP---ISAHYFTVFP-LARWSAVLG------
MUL_1793|M.ulcerans_Agy99 P-GGKALQRLLSQAYVEATFP---ISAHYFTVFP-LARWSAVLG------
MAV_3378|M.avium_104 P-GGKALQRLLSQAYVELTFP---ISAHYFTVIP-LAKRMAALG------
Mvan_2671|M.vanbaalenii_PYR-1 P-FGKSLQRLISQAFVELTFP---LAAQYFTVNP-MAKRMGAVG------
Mflv_4607|M.gilvum_PYR-GCK APGAQIAARGASQAFVELTFP---VAAHFHTAIP-LASAIERAA------
MSMEG_0816|M.smegmatis_MC2_155 VPLTQRVVRAITDAIYAFMVD---TAVLKHRYFRRLNIAAADLG------
MLBr_00065|M.leprae_Br4923 DKYAYTAVRWKNILRQSALYG-------ACQKWP-QRMRNILLG------
.
MAB_4017c|M.abscessus_ATCC_199 YLGWLRYKVKDPEVRQQLRPRFGAGCTRGTLGA--DYLPTFNRANVTLVS
TH_2450|M.thermoresistible__bu FRVLLRAVVHDPQTRRRLMPAHGILAKRPIISG--SYLPAFNDPRTHLIT
Mb1428c|M.bovis_AF2122/97 -RRYLRQQVHDPVVREQLTPRYAVGCKRPGFHN--TYLSTFNRDNVRLVT
Rv1393c|M.tuberculosis_H37Rv -RRYLRQQVHDPVVREQLTPRYAVGCKRPGFHN--TYLSTFNRDNVRLVT
MMAR_2207|M.marinum_M -RRYLRQRVNDPVVRDQLTPRYAVGCKRPGFHN--GYLSTFNRDNVQLVT
MUL_1793|M.ulcerans_Agy99 -RRYLRQRVDDPVVRDQLTPRYAVDCKRPGFHN--GYLSTFNRDNVQLVT
MAV_3378|M.avium_104 -RAYLRRQVRDPAVREQLTPRYAVGCKRPGFHN--GYLATFNRDNVRLVT
Mvan_2671|M.vanbaalenii_PYR-1 -RAYLRKQVDDPVLRDKLTPRYAVGCKRPGFHN--TYLSTFNRDNVDLVT
Mflv_4607|M.gilvum_PYR-GCK -ISYMRRQVTDPVVREKLTPRYALGCKRPSFHN--EYLKTFNRENVLLET
MSMEG_0816|M.smegmatis_MC2_155 -RLHLAASIRDPDLRSKLTPDYDFGCKRPTFSN--SYYRTFTKPHVHLQA
MLBr_00065|M.leprae_Br4923 --HVARRLPKGYDVQKHFGPHYNPWEQRLCLVPDGDLFRAIRKGTVDMVT
. : :: * . * : :: . : :
MAB_4017c|M.abscessus_ATCC_199 NGIERITPTGIVDRAGTERPIDVLVLATGYEMFSDP---ETYRVGTVLGT
TH_2450|M.thermoresistible__bu TPIERITAAGVRTTDGVERPVDLIVTATGYELWTDP---ETYFPGTILGD
Mb1428c|M.bovis_AF2122/97 EPIDKITPTAVATTDGASHEIDVLVLATGFKVLDT----DSIPTYAVTGT
Rv1393c|M.tuberculosis_H37Rv EPIDKITPTAVATTDGASHEIDVLVLATGFKVLDT----DSIPTYAVTGT
MMAR_2207|M.marinum_M EPIEKITPTAVATDDGTDHEIDVLILATGFKVLDT----DDVLTYPVIGR
MUL_1793|M.ulcerans_Agy99 EPIEKITPTSVATDDGTDHEIDVLILATGFKVLDT----DDVLTYPVIGR
MAV_3378|M.avium_104 EPIDKITPDAVATTDGETHEIDVLILATGFKVMDP----DSVPTFAVTGS
Mvan_2671|M.vanbaalenii_PYR-1 EPIDKITGSGVSTTDGSLHEVDVLILATGFKVFAAHDGDDSVATFPVTGP
Mflv_4607|M.gilvum_PYR-GCK NPITRVDETAVITADGVRHEIDVLVLATGFKVMES----DSMPTYSLRGV
MSMEG_0816|M.smegmatis_MC2_155 DGIDHVEPDGIVNADGSKTVIDTLVLATGFDLWEA-----NFPAIEVIGR
MLBr_00065|M.leprae_Br4923 DAIDRFTSTGIRLKSGNELRADIIVTATGLNLQLFG------------GA
* :. .: * * :: *** .: *
MAB_4017c|M.abscessus_ATCC_199 KGFDLAEFYRDNGLQAYQSTSVPGLPNRFMLVGPYSWTGTSFHYILENSM
TH_2450|M.thermoresistible__bu AGFDLALDYRENGLRSYGGTAHPRLPNRWEIVGPLAFVGVGWTDFVETMA
Mb1428c|M.bovis_AF2122/97 GGASLSRFWDEHRLQAYEGVSVPGYPNFFTVFGPYGYVGSSYFALIETQA
Rv1393c|M.tuberculosis_H37Rv GGASLSRFWDEHRLQAYEGVSVPGYPNFFTVFGPYGYVGSSYFALIETQA
MMAR_2207|M.marinum_M AGRSLSQFWEEHRAQAYQGVSVPGYPNFFAVFGPYGYVGSSYFALIETQT
MUL_1793|M.ulcerans_Agy99 AGRSLSQFWEEHRAQAYQGVSVPGYRNFFAVFGPYGYVGSSYFALIETQT
MAV_3378|M.avium_104 GGRSLSRFWDEHRLQAYEGVTVPGFPNLFTVFGPYGYVGSSYFALIEAQT
Mvan_2671|M.vanbaalenii_PYR-1 GGRSLARFWDDNRLQAYEGVSVPGFPNFFTVFGPYGYVGSSYFALIEAQT
Mflv_4607|M.gilvum_PYR-GCK AGRDQAQWWDENRLQAYEGVSVPGFPNHFSVFGPYGYNGSSYFALIEAQA
MSMEG_0816|M.smegmatis_MC2_155 QGRDLGKWWRETRFQAYQGVSMPYFPNYLSLAGPYAFLGLNFFNTMEYQM
MLBr_00065|M.leprae_Br4923 VATVDGQPVDLAQTMSYKGMMLSGLPNMIYTVG---YTNASWTLKADLVS
. . :* . . * * : . .: :
MAB_4017c|M.abscessus_ATCC_199 RHIEAVLKLARARRATWVEVTQEALDDFQASISRSGANLNRYFTVNCA--
TH_2450|M.thermoresistible__bu EHAVRIIDAARRRGADVVTVTDEAFGRWDARMRKAGKAARLYYTRCNP--
Mb1428c|M.bovis_AF2122/97 HHIIRCLKRARRTGATRIEVTEEANARYFAEVMRR-RHRQVFWQDSCR--
Rv1393c|M.tuberculosis_H37Rv HHIIRCLKRARRTGATRIEVTEEANARYFAEVMRR-RHRQVFWQDSCR--
MMAR_2207|M.marinum_M HHILRCLKRARRDGATRVEVTEEANARYFAEMMRR-RYRQVFWQDSCR--
MUL_1793|M.ulcerans_Agy99 HHILRCLKRARRDGATRVEVTEEANARYFAEMMRR-RYRQVFWQDSCR--
MAV_3378|M.avium_104 HHIVRCLKRAQRLGATRVEVSEEANDRYFAEMMRR-RHRQIFWQDSCR--
Mvan_2671|M.vanbaalenii_PYR-1 RHIVRCLDAARRRRATRVEVRREANDRYFAEMMRK-RHRQIFWQDSCQ--
Mflv_4607|M.gilvum_PYR-GCK GHILRCLRHARTADSNYVEVREEANQRFFAEMLAR-RHTQVFWQDSCA--
MSMEG_0816|M.smegmatis_MC2_155 RLMERLLGEVARRDARTFEVTEEANRRYLDRMTDA-LGDSLFTLGNCA--
MLBr_00065|M.leprae_Br4923 EFFCRLLNYMNANDFDTVAVEYPGSDVEERPFMDFTPGYVLRSLDALPKQ
: . * . .
MAB_4017c|M.abscessus_ATCC_199 GSNSYFINSQGDTPYVRPWTVLQSYRRSVQFPSTAYEFKR----ISSPVK
TH_2450|M.thermoresistible__bu GVNTYYVNSQRDTVYHRPQTITESLVFAHRPPLTDYRFERRPAAARSAVR
Mb1428c|M.bovis_AF2122/97 LANSYYFDKNGDVP-LRPTTTVEAYWRSRRFDLGDYRISS----------
Rv1393c|M.tuberculosis_H37Rv LANSYYFDKNGDVP-LRPTTTVEAYWRSRRFDLGDYRISS----------
MMAR_2207|M.marinum_M RANSYYFDKNGDVP-LRPTTTVEAYWRGRHFDLDNYRFGR----------
MUL_1793|M.ulcerans_Agy99 RANSYYFDKNGDVP-LRPTTTVEAYWRGRHFDLDDYRFGR----------
MAV_3378|M.avium_104 LANSYYFDKNGDVP-LRPGTTPEVYWRSRRFDLDDYRFTG----------
Mvan_2671|M.vanbaalenii_PYR-1 LSNSYYFDQHGDVP-LRPASTPEAYWRSRRFPIDDYEFSC----------
Mflv_4607|M.gilvum_PYR-GCK GANSYYFDKHGDVP-LRPTTTVESIWRSRRFDLADYRFERRPAKKADTAP
MSMEG_0816|M.smegmatis_MC2_155 SARSYYFNPSGEATLLRPMTTRRAVAEASRFPLSDYTFA-----------
MLBr_00065|M.leprae_Br4923 GSRTPWRLNQNYLRDIRLIRRGKVADEGLLFAKKTTPVTV----------
.: : * . . .
MAB_4017c|M.abscessus_ATCC_199 EIEHAV-----
TH_2450|M.thermoresistible__bu ALRHAEGNEAV
Mb1428c|M.bovis_AF2122/97 -----------
Rv1393c|M.tuberculosis_H37Rv -----------
MMAR_2207|M.marinum_M -----------
MUL_1793|M.ulcerans_Agy99 -----------
MAV_3378|M.avium_104 -----------
Mvan_2671|M.vanbaalenii_PYR-1 -----------
Mflv_4607|M.gilvum_PYR-GCK QKVDTAG----
MSMEG_0816|M.smegmatis_MC2_155 -----------
MLBr_00065|M.leprae_Br4923 -----------