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MIRSILIILFAAAFAVVPACSSEALDPTKMPMPGAYLPKNTYRLKIEFSSVLNLPGRAKVDSGGVQVGLL DRVELKGTTPVAYVEIDGDAKFPENVRAELRQATVLGDIYIAMISPKDPATTHLKDGDTITLANTVPAAN VEDLMRSMSNLIGGGSLNTMQTTVANMNSAFPPPEELDRIHRALAGVIHDLSSNQDTLNKILTNMQTVSE SFRANKGTYLRLLSEGPTKLPSLAKVVLSLSDLIINASEFGRQIGQILDYPNLMQILSYLTPFVHSASTA DTTIPVLGDKMVRTIRDRIIPFFKDGGPKYTVTDIQNPDGTLGVSPGERADSVIRNMQTMGLVR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4034 | - | - | 100% (344) | putative Mce family protein |
| M. abscessus ATCC 19977 | MAB_4564c | - | 1e-23 | 27.05% (281) | putative Mce family protein |
| M. abscessus ATCC 19977 | MAB_4595c | - | 1e-21 | 33.33% (162) | putative Mce family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0179 | lprK | 4e-16 | 25.11% (219) | MCE-family lipoprotein LprK |
| M. gilvum PYR-GCK | Mflv_0006 | - | 6e-21 | 26.00% (250) | hypothetical protein Mflv_0006 |
| M. tuberculosis H37Rv | Rv0173 | lprK | 4e-16 | 25.11% (219) | MCE-family lipoprotein LprK |
| M. leprae Br4923 | MLBr_02593 | lprK | 1e-16 | 23.53% (357) | putative lipoprotein |
| M. marinum M | MMAR_3868 | mce5E | 3e-23 | 28.06% (253) | Mce family protein, Mce5E |
| M. avium 104 | MAV_5048 | - | 2e-26 | 35.57% (194) | putative Mce family protein |
| M. smegmatis MC2 155 | MSMEG_1147 | - | 1e-25 | 26.79% (265) | mce related protein |
| M. thermoresistible (build 8) | TH_4097 | - | 2e-21 | 26.69% (251) | PUTATIVE mce related protein |
| M. ulcerans Agy99 | MUL_3800 | mce5E | 1e-23 | 28.46% (253) | Mce family protein, Mce5E |
| M. vanbaalenii PYR-1 | Mvan_0963 | - | 3e-20 | 32.14% (196) | hypothetical protein Mvan_0963 |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_1147|M.smegmatis_MC2_155 ------MMAASPKRLRKVRLVAAFAMT-VIVSGCATNGLADLPLP--APG
TH_4097|M.thermoresistible__bu ---------MSVLRLR--RLVPALVTVGCLVSGCATNGLADLPLP--APG
Mflv_0006|M.gilvum_PYR-GCK -----------MMTRRAATALAVAMTTCLSVTSCATEGLSSLPLP--APG
Mvan_0963|M.vanbaalenii_PYR-1 ------------MAIRAKGLMALLVTTSLSVSACATEGLASLPLP--APS
MMAR_3868|M.marinum_M -------------MSGFGKAAAAIAMTTLLSSGCAANGLDSLPLP--APT
MUL_3800|M.ulcerans_Agy99 -------------MSGFGKAAAAIAVTTLLSSGCAANGLDSLPLP--APT
Mb0179|M.bovis_AF2122/97 ---MMSVLARMRVMRHRAWQGLVLLVLALLLSSCGWRGISNVAIPG-GPG
Rv0173|M.tuberculosis_H37Rv ---MMSVLARMRVMRHRAWQGLVLLVLALLLSSCGWRGISNVAIPG-GPG
MLBr_02593|M.leprae_Br4923 MRRAMSVVHTSRVR-HQTWRGLVMLVAALLLSSCGWRGISNVSIPG-GPG
MAB_4034|M.abscessus_ATCC_1997 --------------MIRSILIILFAAAFAVVPACSSEALDPTKMPMPGAY
MAV_5048|M.avium_104 --------------------------------------MNALPQPG---K
: *
MSMEG_1147|M.smegmatis_MC2_155 VGSGGYRITAIFSNALNLPANAKVKLAGADIGEMDSMVARNYTAVTTLRI
TH_4097|M.thermoresistible__bu VGSGGYRLTAEFTNALNLPANAKVKLAGADVGEVESMVARDYLAVTTLRI
Mflv_0006|M.gilvum_PYR-GCK GGSGGYTLTAVFSNALNLPAMAKVKLAGADIGQLESMQARDYTAVTTLRI
Mvan_0963|M.vanbaalenii_PYR-1 GGSGGYTLTAVFSNALNVPMMAKVKLAGADVGELESMQARDYTAVTTLRI
MMAR_3868|M.marinum_M LGSGGYTLTAVFADALNLPMNAKVKLAGADVGQVESMVARNYTAVTRLRI
MUL_3800|M.ulcerans_Agy99 LGSGGYTLTAVFADALNLPMNAKVKLAGADVGQVESMVARNYTAVTRLRI
Mb0179|M.bovis_AF2122/97 TGPGSYTIYVQMPDTLAINGNSRVMVADVWVGSIRAIKLKNWVATLTLSL
Rv0173|M.tuberculosis_H37Rv TGPGSYTIYVQMPDTLAINGNSRVMVADVWVGSIRAIKLKNWVATLTLSL
MLBr_02593|M.leprae_Br4923 SGKGAYTIYVQVPDTLAINGNSKVMVADVTVGSIRAINLKNWVATLTLGL
MAB_4034|M.abscessus_ATCC_1997 LPKNTYRLKIEFSSVLNLPGRAKVDSGGVQVGLLDRVELKGTTPVAYVEI
MAV_5048|M.avium_104 SYSDGYELAIEFANVLNLPERAKVVQDGTTVGVVTRIELKSNHVDVISRI
. * : ....* : ::* .. :* : : :. :
MSMEG_1147|M.smegmatis_MC2_155 MEGVRLPEGSTAELRSATPLGDVFIAIKPPAP-VEPGTPLLKDGDTIDLD
TH_4097|M.thermoresistible__bu MDGVRLPRGSTAELRSATPLGDVFVAIKPPID-VPPDTPMLRDGDTIGKD
Mflv_0006|M.gilvum_PYR-GCK REGVLLPVGSTAELRSATPLGDVFVSIKPPPS-AGQGTPLLTDGDTIGLE
Mvan_0963|M.vanbaalenii_PYR-1 REGVQLPKGSTAELRSATPLGDVFIAIKPPPS-VQPGAALLRDGDTIGLE
MMAR_3868|M.marinum_M TDDVRLPRGSTAELRTATPLGDVFVALRPPAG-AGTEAAMLKDGDTIGLD
MUL_3800|M.ulcerans_Agy99 TDDVRLPRGSTAELRTATPLGDVFVALRPPAG-AGTEAAMLKDGDTIGLD
Mb0179|M.bovis_AF2122/97 KKDVTLPKNATAKIGQTSLLGSQHVELAAPP---DPSPVPLKDGDTIPLK
Rv0173|M.tuberculosis_H37Rv KKDVTLPKNATAKIGQTSLLGSQHVELAAPP---DPSPVPLKDGDTIPLK
MLBr_02593|M.leprae_Br4923 NKDVQLPKNTTAKIGQTSLLGSQHVELAAPA---NPSLELLKNGDTIPLK
MAB_4034|M.abscessus_ATCC_1997 DGDAKFPENVRAELRQATVLGDIYIAMISPK---DPATTHLKDGDTITLA
MAV_5048|M.avium_104 DRDVAVPSNVHATLQQSTVLGDTYVALERPQQGADAAAAPAGENGRIPLA
.. .* . * : :: **. .: : * :.. *
MSMEG_1147|M.smegmatis_MC2_155 ATAAAATVESVLSSAAILVNGGAVRNFTNLINGMGKATGDQGQAFGNLIR
TH_4097|M.thermoresistible__bu STKAAATVESVLASAAILVNGGAVRNFTNIINGLGKATGDEGQAFGNLVR
Mflv_0006|M.gilvum_PYR-GCK STTAAATVESVLSSAAILVNGGAVRNFTNIINGLGKATGDQGQAFGELIR
Mvan_0963|M.vanbaalenii_PYR-1 STTAAATVESVLSSAAILVNGGAVRNFTNIINGLGKATGDQGRAFGDLIR
MMAR_3868|M.marinum_M STTAAATVESVLSSAAILVNGGAIRNFTNMINGFGNATGDQGQAFGNLIR
MUL_3800|M.ulcerans_Agy99 STTAAATVESVLSSAAILVNGGAIRNFTNMINGFGNATGDQGQAFGNLIR
Mb0179|M.bovis_AF2122/97 RSSAYPTTEQTLASIATLLRGGGLVNLEGIQQEINAIVTGRADQIRAFLG
Rv0173|M.tuberculosis_H37Rv RSSAYPTTEQTLASIATLLRGGGLVNLEGIQQEINAIVTGRADQIRAFLG
MLBr_02593|M.leprae_Br4923 NSSVFPTTEQTLASLSLILRGGGIPNLETLTNEVFNIFHGRADQIHAFLT
MAB_4034|M.abscessus_ATCC_1997 NTVPAANVEDLMRSMSNLIGGGSLNTMQTTVANMNSAFP-PPEELDRIHR
MAV_5048|M.avium_104 QTTSPPQLEDTIANMANFVGSGSVQRIQNTIIGINNVTPSRNAELHKISS
: . *. : . : :: .*.: : . : :
MSMEG_1147|M.smegmatis_MC2_155 KTNNTLATLTARSEEISTAMTETSRLAQQISAKNQALSDVMA-QARPATD
TH_4097|M.thermoresistible__bu KTNATLAKLNARSAEISTAMTETSRLASEIAAKNQVLSEVMA-EARPATD
Mflv_0006|M.gilvum_PYR-GCK KTNHTLGTLNGRSEEIKTALTETSQLAAQLEAKNQSLAEVMD-AAAPATS
Mvan_0963|M.vanbaalenii_PYR-1 KTNSTLGTMNARSGEISTAITETSRLAAQMEAKNAALGEVMD-AAGPAAD
MMAR_3868|M.marinum_M KSNRLLATLDSRSEQISTGLSELASLAEQLDAKNQAVTELMA-AAEPAAD
MUL_3800|M.ulcerans_Agy99 KSNRLLATLDSRSEQISTGLSELASLAEQLDAKNQAVTELMA-AAEPAAD
Mb0179|M.bovis_AF2122/97 KLDTFTDELNQQRDDITRAIDSTNRLLAYVGGRSEVLNRVLT-DLPPLIK
Rv0173|M.tuberculosis_H37Rv KLDTFTDELNQQRDDITRAIDSTNRLLAYVGGRSEVLNRVLT-DLPPLIK
MLBr_02593|M.leprae_Br4923 KLDTFASQLNQQRDDITHAIDSTNRLLTYVGGRSDVLDQILT-DIPPLIK
MAB_4034|M.abscessus_ATCC_1997 ALAGVIHDLSSNQDTLNKILTNMQTVSESFRANKGTYLRLLS-EGPTKLP
MAV_5048|M.avium_104 RVVADLKDLSNNIDVVDTWLNGVSGTGQVMHQNLPIYRYWFSPDGMLGFD
: . : : . . :
MSMEG_1147|M.smegmatis_MC2_155 TLAAHTTQIADLVTQIGDVSDQLRKFPSIAGADTSGRSVIADANTVAGAW
TH_4097|M.thermoresistible__bu TLAGHATEIADLVERFGGISDQAHRFPSIAGTDTSGRSVIADANTIANAW
Mflv_0006|M.gilvum_PYR-GCK TLAAQTNGIADLVLTVGATTEQLRKFPSIAGTDTSGRSVIADASRIAGAW
Mvan_0963|M.vanbaalenii_PYR-1 TLAAHTDEIADLVQQVGATAELLRRFPSIAGSDTSGRSVIADANQIAGAW
MMAR_3868|M.marinum_M ALAANTGELSNLVVQVGDTTRLLARFPALGGTDTSGRSMIRDLNTIAGAA
MUL_3800|M.ulcerans_Agy99 ALAANTGELSNLVVQVGDTTRLLARFPALGGTDTSGRSMIRDLNTIAGAA
Mb0179|M.bovis_AF2122/97 HFADKQELLINASDAVGRLSQSADQYLSAARG-----DLHQDLQALQCPL
Rv0173|M.tuberculosis_H37Rv HFADKQELLINASDAVGRLSQSADQYLSAARG-----DLHQDLQALQCPL
MLBr_02593|M.leprae_Br4923 HFADTKNLLINAVGSVGQLSQAVDQYLSEARG-----PLHTDLQALACPL
MAB_4034|M.abscessus_ATCC_1997 SLAKVVLSLSDLIINASEFGRQIGQILDYPNLMQILSYLTPFVHSASTAD
MAV_5048|M.avium_104 RGTQTASYIGTVLPSIGSIYSGGFWLVPTLES------LANATGAVQHTK
: : . : .
MSMEG_1147|M.smegmatis_MC2_155 NDVALAPDATLYALNRLLPPFIKSMSSGAISLDASVDRLILGSTPDIGFA
TH_4097|M.thermoresistible__bu NDVALAPGATLYALNRLMPPFIKTMSGGSVALDASVDRLVWGHHPDIGFA
Mflv_0006|M.gilvum_PYR-GCK NDVVLAPGADLYSLNRLMPPFIKSTTSNAIAVRASIDRLVLGSIPDIGFA
Mvan_0963|M.vanbaalenii_PYR-1 NDVVLAPGADLYSLNKLMPPFIKSTTSNAIAVNASIDRLVLGSIPDIGFA
MMAR_3868|M.marinum_M NDIAVSPDTSWLALNRMIPPMVKSTAGGALSVRASVDRLVLGSIPDIGFP
MUL_3800|M.ulcerans_Agy99 NDIAVSPDTSWLALNRMIPPMVKSTARGALSVRASVDRLVLGSIPDIGFP
Mb0179|M.bovis_AF2122/97 KELRRAAPYLVGALKLILTQPFDVDT---------VPQLVRGDYMNLSLT
Rv0173|M.tuberculosis_H37Rv KELRRAAPYLVGALKLILTQPFDVDT---------VPQLVRGDYMNLSLT
MLBr_02593|M.leprae_Br4923 RELGRGAPYFIGAMKLILTQPYDVDT---------VPKIMRGDYQNVSLT
MAB_4034|M.abscessus_ATCC_1997 TTIPVLGDKMVRTIRDRIIPFFKDGG----------PKYTVTDIQNP---
MAV_5048|M.avium_104 WDFEREAPAWRKLFYEDFLPVDKNPAINITSIKGPDGREMIGNVQDV---
. : : . : :
MSMEG_1147|M.smegmatis_MC2_155 GDQGLHGPKRHDWHQLVGTLKYTLLRLQERVVGQGPGVPQVPVIPSPTEP
TH_4097|M.thermoresistible__bu GDPGLHGPKWSDWHQLVGTLQYTLFRLQERVVGKGPDVPQLPVIPSPTEP
Mflv_0006|M.gilvum_PYR-GCK GDPGLHGPKRYNWHQLVGSLRYTLLRLQERVVGKGPGVPQMPVIPSPTEP
Mvan_0963|M.vanbaalenii_PYR-1 GDSGLHGPKRYNWHQLVGSLQYTLYRLQERIVGKGPGVPQVPVMPHPTEP
MMAR_3868|M.marinum_M GDIGLHGPHRYNWNQFIGSLKYTLWRLQERVVGRGPGSPQLPVMPDPEVP
MUL_3800|M.ulcerans_Agy99 GDVGLHGPHRYNWNQFIGSLKYTLWRLQERVVGRGPGSPQLPVMPDPEVP
Mb0179|M.bovis_AF2122/97 LDLTYS---AIDNAFLTGTGFSGALRALEQSFGRDPE-TMIPDIRYTPNP
Rv0173|M.tuberculosis_H37Rv LDLTYS---AIDNAFLTGTGFSGALRALEQSFGRDPE-TMIPDIRYTPNP
MLBr_02593|M.leprae_Br4923 LDVTYS---AMDNAVLTGTGLSGALRALEQSFGRDPE-TMIPDVRYTTNP
MAB_4034|M.abscessus_ATCC_1997 ----------------------------DGTLGVSPGERADSVIRNMQTM
MAV_5048|M.avium_104 ----------------------------LRILGATP--------------
.* *
MSMEG_1147|M.smegmatis_MC2_155 GEIIVEPGAAAPPEDAPAPEPAPAAQAPAPLPAEAPR--
TH_4097|M.thermoresistible__bu GEIIPAPGPAAG-----------------AAPEEAPR--
Mflv_0006|M.gilvum_PYR-GCK GQWAPAPPPGPVPPGPAP-----------AVAPPAPGVP
Mvan_0963|M.vanbaalenii_PYR-1 GLIVPVPAPAP-PPG--------------APAPEAPR--
MMAR_3868|M.marinum_M GEIQIAPPLSP------------------QPPGPPP---
MUL_3800|M.ulcerans_Agy99 DEIQIAPPLSP------------------QPPGPPP---
Mb0179|M.bovis_AF2122/97 NDAPGGPLVER-------------------GNRQC----
Rv0173|M.tuberculosis_H37Rv NDAPGGPLVER-------------------GNRQC----
MLBr_02593|M.leprae_Br4923 NDAPGGPLVER-------------------ADRRC----
MAB_4034|M.abscessus_ATCC_1997 GLVR-----------------------------------
MAV_5048|M.avium_104 ---------------------------------------