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NRWQKLAGPAVVAAVLLTSGCSTNGLASLPLPAPGMTGGSYGLTAVFTNILNLPARAKVKLGGADIGEVD SMSTANYTAVVTMRIRSDVEIPKRTTVELRTATPLGDVFVALKPPRPAVPDAPLLRDGDTIGLDATTAAA TVEAVLSSAAIIVNGGAVRNLTGTVNGLGRATGTNGQAFGDLIGKSNRLLSTLNARSSQLDSALRDTAQL AAEMNTRHDTLSDLLVAAAPATDTLAANASHIADLADQVGLVTKQLSKFPSIAGTDTSGRSVIADFNTLS ASFNDITVSPDTSLAALNRLMPPIIKIMAGSAFAARVSIDKLALGSIPDIGYQGDPGFHGPKRYDWAKLV GSFKYTLWRLQERVVGKGPDAPAIPMRPSPTEPGVIEPVPGAAPVPQEPPR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4564c | - | - | 100% (402) | putative Mce family protein |
| M. abscessus ATCC 19977 | MAB_1006c | - | e-139 | 61.40% (399) | putative MCE family protein |
| M. abscessus ATCC 19977 | MAB_4512c | - | e-135 | 60.88% (386) | putative Mce family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0179 | lprK | 3e-23 | 26.59% (267) | MCE-family lipoprotein LprK |
| M. gilvum PYR-GCK | Mflv_0006 | - | 1e-135 | 60.25% (400) | hypothetical protein Mflv_0006 |
| M. tuberculosis H37Rv | Rv0173 | lprK | 3e-23 | 26.59% (267) | MCE-family lipoprotein LprK |
| M. leprae Br4923 | MLBr_02593 | lprK | 3e-24 | 25.86% (263) | putative lipoprotein |
| M. marinum M | MMAR_3868 | mce5E | 1e-134 | 58.12% (394) | Mce family protein, Mce5E |
| M. avium 104 | MAV_2384 | - | 1e-132 | 57.65% (392) | mce related protein |
| M. smegmatis MC2 155 | MSMEG_1147 | - | 1e-139 | 60.15% (399) | mce related protein |
| M. thermoresistible (build 8) | TH_4097 | - | 1e-136 | 60.00% (395) | PUTATIVE mce related protein |
| M. ulcerans Agy99 | MUL_3800 | mce5E | 1e-133 | 57.61% (394) | Mce family protein, Mce5E |
| M. vanbaalenii PYR-1 | Mvan_0963 | - | 1e-135 | 59.90% (389) | hypothetical protein Mvan_0963 |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_1147|M.smegmatis_MC2_155 ------MMAASPKRLRKVRLVAAFAMT-VIVSGCATNGLADLPLP-APGV
TH_4097|M.thermoresistible__bu ---------MSVLRLR--RLVPALVTVGCLVSGCATNGLADLPLP-APGV
Mflv_0006|M.gilvum_PYR-GCK -----------MMTRRAATALAVAMTTCLSVTSCATEGLSSLPLP-APGG
Mvan_0963|M.vanbaalenii_PYR-1 ------------MAIRAKGLMALLVTTSLSVSACATEGLASLPLP-APSG
MMAR_3868|M.marinum_M --------MSGFG-----KAAAAIAMTTLLSSGCAANGLDSLPLP-APTL
MUL_3800|M.ulcerans_Agy99 --------MSGFG-----KAAAAIAVTTLLSSGCAANGLDSLPLP-APTL
MAV_2384|M.avium_104 --------MTATGARGRLTALAAAMAVTTATAGCATNGLASLPLP-APGL
MAB_4564c|M.abscessus_ATCC_199 ------------MNRWQKLAGPAVVAAVLLTSGCSTNGLASLPLP-APGM
Mb0179|M.bovis_AF2122/97 ---MMSVLARMRVMRHRAWQGLVLLVLALLLSSCGWRGISNVAIPGGPGT
Rv0173|M.tuberculosis_H37Rv ---MMSVLARMRVMRHRAWQGLVLLVLALLLSSCGWRGISNVAIPGGPGT
MLBr_02593|M.leprae_Br4923 MRRAMSVVHTSRVR-HQTWRGLVMLVAALLLSSCGWRGISNVSIPGGPGS
:.*. .*: .:.:* .*
MSMEG_1147|M.smegmatis_MC2_155 GSGGYRITAIFSNALNLPANAKVKLAGADIGEMDSMVARNYTAVTTLRIM
TH_4097|M.thermoresistible__bu GSGGYRLTAEFTNALNLPANAKVKLAGADVGEVESMVARDYLAVTTLRIM
Mflv_0006|M.gilvum_PYR-GCK GSGGYTLTAVFSNALNLPAMAKVKLAGADIGQLESMQARDYTAVTTLRIR
Mvan_0963|M.vanbaalenii_PYR-1 GSGGYTLTAVFSNALNVPMMAKVKLAGADVGELESMQARDYTAVTTLRIR
MMAR_3868|M.marinum_M GSGGYTLTAVFADALNLPMNAKVKLAGADVGQVESMVARNYTAVTRLRIT
MUL_3800|M.ulcerans_Agy99 GSGGYTLTAVFADALNLPMNAKVKLAGADVGQVESMVARNYTAVTRLRIT
MAV_2384|M.avium_104 GSGGYSLNAVFSNALNLPMNAKVKLAGADVGQLESMVARNYTALTRLRIR
MAB_4564c|M.abscessus_ATCC_199 TGGSYGLTAVFTNILNLPARAKVKLGGADIGEVDSMSTANYTAVVTMRIR
Mb0179|M.bovis_AF2122/97 GPGSYTIYVQMPDTLAINGNSRVMVADVWVGSIRAIKLKNWVATLTLSLK
Rv0173|M.tuberculosis_H37Rv GPGSYTIYVQMPDTLAINGNSRVMVADVWVGSIRAIKLKNWVATLTLSLK
MLBr_02593|M.leprae_Br4923 GKGAYTIYVQVPDTLAINGNSKVMVADVTVGSIRAINLKNWVATLTLGLN
*.* : . ..: * : ::* :... :*.: :: :: * : :
MSMEG_1147|M.smegmatis_MC2_155 EGVRLPEGSTAELRSATPLGDVFIAIKPPAPVEPGTPLLKDGDTIDLDAT
TH_4097|M.thermoresistible__bu DGVRLPRGSTAELRSATPLGDVFVAIKPPIDVPPDTPMLRDGDTIGKDST
Mflv_0006|M.gilvum_PYR-GCK EGVLLPVGSTAELRSATPLGDVFVSIKPPPSAGQGTPLLTDGDTIGLEST
Mvan_0963|M.vanbaalenii_PYR-1 EGVQLPKGSTAELRSATPLGDVFIAIKPPPSVQPGAALLRDGDTIGLEST
MMAR_3868|M.marinum_M DDVRLPRGSTAELRTATPLGDVFVALRPPAGAGTEAAMLKDGDTIGLDST
MUL_3800|M.ulcerans_Agy99 DDVRLPRGSTAELRTATPLGDVFVALRPPAGAGTEAAMLKDGDTIGLDST
MAV_2384|M.avium_104 DGVQLPRGSTAELRTATPLGDVFVALKPPPGD-HDAPLLKNGDTIGLEST
MAB_4564c|M.abscessus_ATCC_199 SDVEIPKRTTVELRTATPLGDVFVALKPPRPAVPDAPLLRDGDTIGLDAT
Mb0179|M.bovis_AF2122/97 KDVTLPKNATAKIGQTSLLGSQHVELAAPPDP--SPVPLKDGDTIPLKRS
Rv0173|M.tuberculosis_H37Rv KDVTLPKNATAKIGQTSLLGSQHVELAAPPDP--SPVPLKDGDTIPLKRS
MLBr_02593|M.leprae_Br4923 KDVQLPKNTTAKIGQTSLLGSQHVELAAPANP--SLELLKNGDTIPLKNS
..* :* :*.:: :: **. .: : .* * :**** . :
MSMEG_1147|M.smegmatis_MC2_155 AAAATVESVLSSAAILVNGGAVRNFTNLINGMGKATGDQGQAFGNLIRKT
TH_4097|M.thermoresistible__bu KAAATVESVLASAAILVNGGAVRNFTNIINGLGKATGDEGQAFGNLVRKT
Mflv_0006|M.gilvum_PYR-GCK TAAATVESVLSSAAILVNGGAVRNFTNIINGLGKATGDQGQAFGELIRKT
Mvan_0963|M.vanbaalenii_PYR-1 TAAATVESVLSSAAILVNGGAVRNFTNIINGLGKATGDQGRAFGDLIRKT
MMAR_3868|M.marinum_M TAAATVESVLSSAAILVNGGAIRNFTNMINGFGNATGDQGQAFGNLIRKS
MUL_3800|M.ulcerans_Agy99 TAAATVESVLSSAAILVNGGAIRNFTNMINGFGNATGDQGQAFGNLIRKS
MAV_2384|M.avium_104 AAAATVESVLSSAAVLVNGGAVRNFTNIINGFGKATGDQGQAFGDMIRKS
MAB_4564c|M.abscessus_ATCC_199 TAAATVEAVLSSAAIIVNGGAVRNLTGTVNGLGRATGTNGQAFGDLIGKS
Mb0179|M.bovis_AF2122/97 SAYPTTEQTLASIATLLRGGGLVNLEGIQQEINAIVTGRADQIRAFLGKL
Rv0173|M.tuberculosis_H37Rv SAYPTTEQTLASIATLLRGGGLVNLEGIQQEINAIVTGRADQIRAFLGKL
MLBr_02593|M.leprae_Br4923 SVFPTTEQTLASLSLILRGGGIPNLETLTNEVFNIFHGRADQIHAFLTKL
. .*.* .*:* : ::.**.: *: : . .. : :: *
MSMEG_1147|M.smegmatis_MC2_155 NNTLATLTARSEEISTAMTETSRLAQQISAKNQALSDVMAQARPATDTLA
TH_4097|M.thermoresistible__bu NATLAKLNARSAEISTAMTETSRLASEIAAKNQVLSEVMAEARPATDTLA
Mflv_0006|M.gilvum_PYR-GCK NHTLGTLNGRSEEIKTALTETSQLAAQLEAKNQSLAEVMDAAAPATSTLA
Mvan_0963|M.vanbaalenii_PYR-1 NSTLGTMNARSGEISTAITETSRLAAQMEAKNAALGEVMDAAGPAADTLA
MMAR_3868|M.marinum_M NRLLATLDSRSEQISTGLSELASLAEQLDAKNQAVTELMAAAEPAADALA
MUL_3800|M.ulcerans_Agy99 NRLLATLDSRSEQISTGLSELASLAEQLDAKNQAVTELMAAAEPAADALA
MAV_2384|M.avium_104 NELLGTLDARSDQISAALTQLSTLADQLDAKNHTITDLMTAAGPATSALA
MAB_4564c|M.abscessus_ATCC_199 NRLLSTLNARSSQLDSALRDTAQLAAEMNTRHDTLSDLLVAAAPATDTLA
Mb0179|M.bovis_AF2122/97 DTFTDELNQQRDDITRAIDSTNRLLAYVGGRSEVLNRVLTDLPPLIKHFA
Rv0173|M.tuberculosis_H37Rv DTFTDELNQQRDDITRAIDSTNRLLAYVGGRSEVLNRVLTDLPPLIKHFA
MLBr_02593|M.leprae_Br4923 DTFASQLNQQRDDITHAIDSTNRLLTYVGGRSDVLDQILTDIPPLIKHFA
: : : :: .: . * : : : :: * . :*
MSMEG_1147|M.smegmatis_MC2_155 AHTTQIADLVTQIGDVSDQLRKFPSIAGADTSGRSVIADANTVAGAWNDV
TH_4097|M.thermoresistible__bu GHATEIADLVERFGGISDQAHRFPSIAGTDTSGRSVIADANTIANAWNDV
Mflv_0006|M.gilvum_PYR-GCK AQTNGIADLVLTVGATTEQLRKFPSIAGTDTSGRSVIADASRIAGAWNDV
Mvan_0963|M.vanbaalenii_PYR-1 AHTDEIADLVQQVGATAELLRRFPSIAGSDTSGRSVIADANQIAGAWNDV
MMAR_3868|M.marinum_M ANTGELSNLVVQVGDTTRLLARFPALGGTDTSGRSMIRDLNTIAGAANDI
MUL_3800|M.ulcerans_Agy99 ANTGELSNLVVQVGDTTRLLARFPALGGTDTSGRSMIRDLNTIAGAANDI
MAV_2384|M.avium_104 DNTGELSEVAQQVGDTSRLLARFPALGGTDTSGRSMIRDLNTIAGAANDV
MAB_4564c|M.abscessus_ATCC_199 ANASHIADLADQVGLVTKQLSKFPSIAGTDTSGRSVIADFNTLSASFNDI
Mb0179|M.bovis_AF2122/97 DKQELLINASDAVGRLSQSADQYLSAARG-----DLHQDLQALQCPLKEL
Rv0173|M.tuberculosis_H37Rv DKQELLINASDAVGRLSQSADQYLSAARG-----DLHQDLQALQCPLKEL
MLBr_02593|M.leprae_Br4923 DTKNLLINAVGSVGQLSQAVDQYLSEARG-----PLHTDLQALACPLREL
: : .* : :: : . : * . : . .::
MSMEG_1147|M.smegmatis_MC2_155 ALAPDATLYALNRLLPPFIKSMSSGAISLDASVDRLILGSTPDIGFAGDQ
TH_4097|M.thermoresistible__bu ALAPGATLYALNRLMPPFIKTMSGGSVALDASVDRLVWGHHPDIGFAGDP
Mflv_0006|M.gilvum_PYR-GCK VLAPGADLYSLNRLMPPFIKSTTSNAIAVRASIDRLVLGSIPDIGFAGDP
Mvan_0963|M.vanbaalenii_PYR-1 VLAPGADLYSLNKLMPPFIKSTTSNAIAVNASIDRLVLGSIPDIGFAGDS
MMAR_3868|M.marinum_M AVSPDTSWLALNRMIPPMVKSTAGGALSVRASVDRLVLGSIPDIGFPGDI
MUL_3800|M.ulcerans_Agy99 AVSPDTSWLALNRMIPPMVKSTARGALSVRASVDRLVLGSIPDIGFPGDV
MAV_2384|M.avium_104 AVSPDTSWQSINRLIPALVKSTAGNSISVNVSVDKIMLGSLPDIGFPGDI
MAB_4564c|M.abscessus_ATCC_199 TVSPDTSLAALNRLMPPIIKIMAGSAFAARVSIDKLALGSIPDIGYQGDP
Mb0179|M.bovis_AF2122/97 RRAAPYLVGALKLILTQPFDVDT---------VPQLVRGDYMNLSLTLDL
Rv0173|M.tuberculosis_H37Rv RRAAPYLVGALKLILTQPFDVDT---------VPQLVRGDYMNLSLTLDL
MLBr_02593|M.leprae_Br4923 GRGAPYFIGAMKLILTQPYDVDT---------VPKIMRGDYQNVSLTLDV
.. ::: ::. . : : :: * ::. *
MSMEG_1147|M.smegmatis_MC2_155 GLHGPKRHDWHQLVGTLKYTLLRLQERVVGQGPGVPQVPVIPSPTEPGEI
TH_4097|M.thermoresistible__bu GLHGPKWSDWHQLVGTLQYTLFRLQERVVGKGPDVPQLPVIPSPTEPGEI
Mflv_0006|M.gilvum_PYR-GCK GLHGPKRYNWHQLVGSLRYTLLRLQERVVGKGPGVPQMPVIPSPTEPGQW
Mvan_0963|M.vanbaalenii_PYR-1 GLHGPKRYNWHQLVGSLQYTLYRLQERIVGKGPGVPQVPVMPHPTEPGLI
MMAR_3868|M.marinum_M GLHGPHRYNWNQFIGSLKYTLWRLQERVVGRGPGSPQLPVMPDPEVPGEI
MUL_3800|M.ulcerans_Agy99 GLHGPHRYNWNQFIGSLKYTLWRLQERVVGRGPGSPQLPVMPDPEVPDEI
MAV_2384|M.avium_104 GLHGPHHYNVNLLVGTLKYTLWRLQERVVGRGPNAPQVPVVPDPTVPGQI
MAB_4564c|M.abscessus_ATCC_199 GFHGPKRYDWAKLVGSFKYTLWRLQERVVGKGPDAPAIPMRPSPTEPGVI
Mb0179|M.bovis_AF2122/97 TYS---AIDNAFLTGTGFSGALRALEQSFGRDPE-TMIPDIRYTPNPNDA
Rv0173|M.tuberculosis_H37Rv TYS---AIDNAFLTGTGFSGALRALEQSFGRDPE-TMIPDIRYTPNPNDA
MLBr_02593|M.leprae_Br4923 TYS---AMDNAVLTGTGLSGALRALEQSFGRDPE-TMIPDVRYTTNPNDA
: : *: * *: .*:.* . :* . *.
MSMEG_1147|M.smegmatis_MC2_155 IVEPGAAAPPEDAPAPEPAPAAQAPAPLPAEAPR--
TH_4097|M.thermoresistible__bu IPAPGPAAG-----------------AAPEEAPR--
Mflv_0006|M.gilvum_PYR-GCK APAPPPGPVPPGPAP-----------AVAPPAPGVP
Mvan_0963|M.vanbaalenii_PYR-1 VPVPAPAP-PPG--------------APAPEAPR--
MMAR_3868|M.marinum_M QIAPPLSP------------------QPPGPPP---
MUL_3800|M.ulcerans_Agy99 QIAPPLSP------------------QPPGPPP---
MAV_2384|M.avium_104 DVAPGPPP------------------PQPGSPP---
MAB_4564c|M.abscessus_ATCC_199 EPVPGAAP-------------------VPQEPPR--
Mb0179|M.bovis_AF2122/97 PGGPLVER-------------------GNRQC----
Rv0173|M.tuberculosis_H37Rv PGGPLVER-------------------GNRQC----
MLBr_02593|M.leprae_Br4923 PGGPLVER-------------------ADRRC----
*