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VPTTKQQAPAKRGGTRTKMLASAAEVMRERGAAGVTIDAVLARSGAPRGSVYYHFPDGRNQILAEALRYS GDSITALIDQAAGRGGRALLREFVEYWERLLTEGGFTAGCPVVAAAIGCSEDEGPKLSAEAGAILGRWCT ALTRAFVNDGFDDADAASLAVMSIAALEGGIVLSRSTRNAGPLHQVGEQLEFLIKAREFVVRNKIPGKQP GSR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_4948 | - | - | 100% (213) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_4985 | - | 5e-33 | 42.08% (183) | regulatory protein, TetR |
| M. avium 104 | MAV_0149 | - | 3e-19 | 28.34% (187) | transcriptional regulator, TetR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0202 | - | 7e-32 | 38.50% (187) | putative transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_3287 | - | 6e-32 | 40.41% (193) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0196 | - | 7e-32 | 38.50% (187) | transcriptional regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1494 | - | 4e-29 | 39.67% (184) | TetR family transcriptional regulator |
| M. marinum M | MMAR_0470 | - | 2e-79 | 73.40% (203) | transcriptional regulatory protein |
| M. smegmatis MC2 155 | MSMEG_3520 | - | 7e-30 | 40.22% (179) | TetR-family protein transcriptional regulator |
| M. thermoresistible (build 8) | TH_3160 | - | 2e-25 | 35.53% (197) | PUTATIVE putative regulatory protein, TetR |
| M. ulcerans Agy99 | MUL_1119 | - | 4e-79 | 72.91% (203) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_0275 | - | 3e-32 | 38.33% (180) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0470|M.marinum_M --MTPPSTSTP-KRGGTREKMLISAAQVMRERGAAGVTIDSVLARSGAPR
MUL_1119|M.ulcerans_Agy99 --MTPPSTSTP-KRGGTREKMLISAAQVMRERGAAGVTIDSVLARSGAPR
MAV_4948|M.avium_104 --MPTTKQQAPAKRGGTRTKMLASAAEVMRERGAAGVTIDAVLARSGAPR
Mb0202|M.bovis_AF2122/97 -------MQGP------RERMVVSAALLIRERGAHATAISDVLQHSGAPR
Rv0196|M.tuberculosis_H37Rv -------MQGP------RERMVVSAALLIRERGAHATAISDVLQHSGAPR
Mflv_3287|M.gilvum_PYR-GCK -------MTTP------RERMVVSAALLIRERGAHPTAIADVLQHSGAPR
MAB_1494|M.abscessus_ATCC_1997 -------MSTP------RERMVASAALLIRERGAHATAISDVLEHSGAPR
MSMEG_3520|M.smegmatis_MC2_155 -------MASP------RERMVRSAAVLIRERGAHPTAIADVLAHSGAPR
Mvan_0275|M.vanbaalenii_PYR-1 ---MSPRTSDA------RERMLDSASTLIREHGASGTSLDDILRHSRAPR
TH_3160|M.thermoresistible__bu MGVEVTRRRDP--QSGPRAAMLRSAVALMRRQGVAATSFADVLADSGAPR
. * *: ** ::*.:*. .:: :* * ***
MMAR_0470|M.marinum_M GSVYYHFPDGRNQILIEALRYAGDSITAVIDKAADKGA--RALLREFVRL
MUL_1119|M.ulcerans_Agy99 GSVYYHFPDGRNQILIEALRYAGDSITAVIDKAADKGA--RALLREFVRL
MAV_4948|M.avium_104 GSVYYHFPDGRNQILAEALRYSGDSITALIDQAAGRGG--RALLREFVEY
Mb0202|M.bovis_AF2122/97 GSAYHYFPGGRTQLLCEAVDYAGEHVAAMINEAEGG----LELLDALIDK
Rv0196|M.tuberculosis_H37Rv GSAYHYFPGGRTQLLCEAVDYAGEHVAAMINEAEGG----LELLDALIDK
Mflv_3287|M.gilvum_PYR-GCK GSAYHYFPGGRTQLLCEAVDYAAEFMAERLSRASSS----LRVLDDLFGY
MAB_1494|M.abscessus_ATCC_1997 GSAYHYFPGGRTQLLSEAVDLAGEYIAGMIDAKPSA----VDALDILVAS
MSMEG_3520|M.smegmatis_MC2_155 GSAYHYFPGGRTQLLCEAIDYASDHVTARLDRATDT----FALLDDMVAR
Mvan_0275|M.vanbaalenii_PYR-1 GSVYHHFPGGRAQLIEEVVDRAGGALAAILGDAGDATP--ATTFDVFIST
TH_3160|M.thermoresistible__bu GSIYHHFPAGKAQLIEEATRTAAAQLTERVARVLDEAADLPTALRELVGV
** *::** *: *:: *. :. :: : . : :.
MMAR_0470|M.marinum_M WEHLLTDGGFAAGCPVVAAALGPADDE-----VELAAEAGTILDSWCAAL
MUL_1119|M.ulcerans_Agy99 WEHLLTDGGFAAGCPVVAAALGPADDE-----VELAAEAGTILDSWCAAL
MAV_4948|M.avium_104 WERLLTEGGFTAGCPVVAAAIGCSEDEG----PKLSAEAGAILGRWCTAL
Mb0202|M.bovis_AF2122/97 YRQQLLSTDFRAGCPIAAVSVEAGDEQDRERMAPVIARAAAVFDRWSDLT
Rv0196|M.tuberculosis_H37Rv YRQQLLSTDFRAGCPIAAVSVEAGDEQDRERMAPVIARAAAVFDRWSDLT
Mflv_3287|M.gilvum_PYR-GCK YRTQLQDSDFRAGCPVVAVAVESGDPDKPEQSAPVIERAAAALTRWSDII
MAB_1494|M.abscessus_ATCC_1997 YRKQLVRSDFRAGCPVVAVAVEAGDPESPASSQKLIEHSAAVFRRWIDLI
MSMEG_3520|M.smegmatis_MC2_155 FRDQLLASDFRAGCPVVAVAVEAGDPEKADSADAVRERAGAAFQRWIARI
Mvan_0275|M.vanbaalenii_PYR-1 WKAGLEASGFRAGCPVLAVAVETND-----DAPQLTEAAARAFGSWRDAL
TH_3160|M.thermoresistible__bu WRDGLEAGDYAVGCPIVAAALGTER--------AARDVAGVAFADLTGLI
:. * .: .***: *.:: :. :
MMAR_0470|M.marinum_M GRAFVADGFDESTAASLAVTSIAALEGAIMLCRSTRSAEPLRQVGEQLEF
MUL_1119|M.ulcerans_Agy99 GRAFVADGFDESTAASLAVTSIAALEGAIMLCRSTRSVEPLRQVGEQLEF
MAV_4948|M.avium_104 TRAFVNDGFDDADAASLAVMSIAALEGGIVLSRSTRNAGPLHQVGEQLEF
Mb0202|M.bovis_AF2122/97 AQRFIADGIPPDRAHELAVLATSTLEGAILLARVRRDLTPLDLVHRQLRN
Rv0196|M.tuberculosis_H37Rv AQRFIADGIPPDRAHELAVLATSTLEGAILLARVRRDLTPLDLVHRQLRN
Mflv_3287|M.gilvum_PYR-GCK EQRLIADGVPRADAAALAMLVLTSFEGAIVVARATRDLKPLDLVAGQLAS
MAB_1494|M.abscessus_ATCC_1997 ADKLVAVGVVRTRADELAILMTTSLEGAIIIARSTRDITPIDVVHRQLRT
MSMEG_3520|M.smegmatis_MC2_155 TARLCDDGVPVERAEELATLITTSVEGAVLVARTTRDVKPLELVHRQLRE
Mvan_0275|M.vanbaalenii_PYR-1 NTVLRHQGVPPARARRLATLIVAAVEGAVALSRVERNTQPIDDVARELRA
TH_3160|M.thermoresistible__bu SDKLVSDGMARRRANSVAVLILTAMEGALVLAQARRDPAALDAVVDELTL
: *. * :* ::.**.: :.: *. .: * :*
MMAR_0470|M.marinum_M LVKARGFVAQSRLDSE-----
MUL_1119|M.ulcerans_Agy99 LVKARGFVAQSRLDSE-----
MAV_4948|M.avium_104 LIKAREFVVRNKIPGKQPGSR
Mb0202|M.bovis_AF2122/97 LLLAELPERSR----------
Rv0196|M.tuberculosis_H37Rv LLLAELPERSR----------
Mflv_3287|M.gilvum_PYR-GCK LIDARTVTRRK----------
MAB_1494|M.abscessus_ATCC_1997 LIEEAGQ--------------
MSMEG_3520|M.smegmatis_MC2_155 QLTAATGKKDRP---------
Mvan_0275|M.vanbaalenii_PYR-1 LIRQATDAS------------
TH_3160|M.thermoresistible__bu LCSGSAD--------------