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MKIAIFGATGMVGSRIAAELRSRGHQVTGYSRRGSDSTRAGTLTDGALVATVAAGHDAVVSAIGPSRSGE PHSEFIEAITAAAANLHGTRLFVVGGAGTLRVNGVRLVDSPEFPEPYRAEALAHAAALDTLEQTAQDVDW VYLSPAPLIEPGKRTGSYRVAGDAPAGQSISAEDYAVAVADELEHPAHRRERFTVAN
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_3697 | - | - | 100% (197) | putative epimerase/dehydratase |
| M. abscessus ATCC 19977 | MAB_4711 | - | 3e-05 | 26.57% (207) | hypothetical protein MAB_4711 |
| M. abscessus ATCC 19977 | MAB_3360c | - | 4e-05 | 32.41% (108) | hypothetical protein MAB_3360c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_3024 | - | 7e-07 | 33.64% (110) | hypothetical protein MMAR_3024 |
| M. avium 104 | MAV_1850 | - | 2e-09 | 26.24% (221) | hypothetical protein MAV_1850 |
| M. smegmatis MC2 155 | MSMEG_4426 | - | 3e-07 | 39.02% (82) | secreted protein |
| M. thermoresistible (build 8) | TH_3570 | - | 5e-08 | 43.68% (87) | PUTATIVE secreted protein |
| M. ulcerans Agy99 | MUL_2265 | - | 5e-07 | 33.64% (110) | hypothetical protein MUL_2265 |
| M. vanbaalenii PYR-1 | Mvan_5001 | - | 3e-05 | 29.59% (169) | NmrA family protein |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3024|M.marinum_M -----MRVAVTGAGGVLGRGLASRLLSQGHEVVGMSRRRP--DSWPSQAD
MUL_2265|M.ulcerans_Agy99 -----MRVAVTGAGGVLGRGLASRLLSQGHEVVGMSRRRP--DSWPSQAD
MSMEG_4426|M.smegmatis_MC2_155 -----MKIVVIGGRGLIGAKVAAKLGAQGHDVTAASRR--------SGVD
Mvan_5001|M.vanbaalenii_PYR-1 -----MLIVVIGGTGLIGSKLIRQLSEHGHRAVAAAPS--------TGVD
TH_3570|M.thermoresistible__bu VEGAVMRITVFGATGRIGSEVVALLRADGHDVVPASLS--------TGAD
MAB_3697|M.abscessus_ATCC_1997 -----MKIAIFGATGMVGSRIAAELRSRGHQVTGYSRR--------GSDS
MAV_1850|M.avium_104 ---MNLRVTVFGATGQIGRFVVADLLADGHAATAYVRNPGKLQVADPHLT
: :.: *. * :* : * ** ..
MMAR_3024|M.marinum_M FVAGDIRDAAAVRRAITGADVVAHCAWARNPGPDGRISQQINIDGTRNVL
MUL_2265|M.ulcerans_Agy99 FVAGDIRDAAAVRRAITGADVVAHCAWARNPGPDGRISQQINIDGTRNVL
MSMEG_4426|M.smegmatis_MC2_155 ALTG-----EGLAAAVAGADVVVDVSGS--PVFDDDPVMRFFVTTTANLL
Mvan_5001|M.vanbaalenii_PYR-1 TVTG-----DGLADVLAGADVVVDVSNS--PSFDDDAALEFFEKSTGNLL
TH_3570|M.thermoresistible__bu VVTG-----AGLADSLSGADVLVDVVNS--PSFADGPVSEFFTAAALNLT
MAB_3697|M.abscessus_ATCC_1997 TRAGTLTDGALVATVAAGHDAVVSAIGPSRSGEPHSEFIEAITAAAANLH
MAV_1850|M.avium_104 VATGELSDAEAVRKAVRGADAVISALGP---SLSRRAKGTPVTEGTRNIV
:* : * *.: . : *:
MMAR_3024|M.marinum_M DAMAACGTGRIVFPSSPHVYRPGVPMPATEHGAVAPASAEGRHKAGVEQM
MUL_2265|M.ulcerans_Agy99 DAMAACGTGRIVFPSSPHVYRPGLPMPATEHGAVAPASAEGRHKAGVEQM
MSMEG_4426|M.smegmatis_MC2_155 SAEWQAGVS------------HHVVLSVVGAQSMPD-SGYNTAKAAQENL
Mvan_5001|M.vanbaalenii_PYR-1 AAEAQAGVG------------HHVALSVVNTDQLAEQSGYFRAKALQERL
TH_3570|M.thermoresistible__bu AAARAAGVG------------HHVALSIVGCDELPD-SGYMRAKAAQERI
MAB_3697|M.abscessus_ATCC_1997 GTRLFVVGG----------------------------AGTLRVNGVRLVD
MAV_1850|M.avium_104 AAMQAEHVS--------------------------------RYIGLATPS
: . .
MMAR_3024|M.marinum_M LQESGAQWVAVRSALIVGRNIDNWVRRLFALPAFPDGSADDVLQVVHLDD
MUL_2265|M.ulcerans_Agy99 LQESGAQWVAVRSALIVGRNIDNWVRRLFALPAFPDGSADDVLQVVHLDD
MSMEG_4426|M.smegmatis_MC2_155 IRDSGRPYTIVRATPFY-------------------EFAVGLADSATDGD
Mvan_5001|M.vanbaalenii_PYR-1 IRQSPVPYTIVHATQFY-------------------EFVKGIADAATDGD
TH_3570|M.thermoresistible__bu IAESGLPYTIVRATQFD-------------------EFAEAIVESLIVGA
MAB_3697|M.abscessus_ATCC_1997 SPEFPEPYRAEALAHAA--------------------ALDTLEQTAQDVD
MAV_1850|M.avium_104 VPDSRDRPTLKAKILP---------------------IIAGTLFPNALGE
:
MMAR_3024|M.marinum_M VLRLLTRAVSDVGAGTGPVNLAAPGLPTLREIAMALRRPILPVGAVLRRI
MUL_2265|M.ulcerans_Agy99 VLRLLTRAVSDVGAGTGPVNLAAPGLPTLREIATALRRPILPVGAALRRI
MSMEG_4426|M.smegmatis_MC2_155 VVRLPHASFRPIAADDVATAVACA--------------------------
Mvan_5001|M.vanbaalenii_PYR-1 IVRLAPVLIQPMAAADVAEAMAIA--------------------------
TH_3570|M.thermoresistible__bu EVRVPDGSIQPIAAADVAAEVAAR--------------------------
MAB_3697|M.abscessus_ATCC_1997 WVYLSPAPLIEPGKRTGSYRVAGD--------------------------
MAV_1850|M.avium_104 IVGMTKAVTDSDLAWTIARITSPN--------------------------
: : . :
MMAR_3024|M.marinum_M GSVAEFQLVQGVPVMDTARLHDEWKFQPAFTAEESVEDFALAVRGRVSLG
MUL_2265|M.ulcerans_Agy99 GSVAEFQLVQGVPVMDTARLHDEWKFQPAFTAEESVEDFALAVRGRVSLG
MSMEG_4426|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_5001|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_3570|M.thermoresistible__bu --------------------------------------------------
MAB_3697|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_1850|M.avium_104 --------------------------------------------------
MMAR_3024|M.marinum_M RRVVSLPWRLANIQDLPAVDAP------AQDGVVPRLAGPEGVNGEFDTP
MUL_2265|M.ulcerans_Agy99 RRVVSLPWRLANIQDLPAIDAS------AQDGVVPRLAGPEGVNGEFDTP
MSMEG_4426|M.smegmatis_MC2_155 -----------------ALGRP------VNG--VTEIAGPEVIG------
Mvan_5001|M.vanbaalenii_PYR-1 -----------------AVGKP------HNR--IVEVAGPQLYR------
TH_3570|M.thermoresistible__bu -----------------AVAEP------AGG--VVNIGGPDRMS------
MAB_3697|M.abscessus_ATCC_1997 --------------------APAGQSISAED-------------------
MAV_1850|M.avium_104 ------------------NSRP----------------------------
.
MMAR_3024|M.marinum_M IDPRFPTFLATNLSEALPGPFSPSSASVTVRGLRAGGVGIAERLRPGGVI
MUL_2265|M.ulcerans_Agy99 IDPRFPTFLATNLSEALPGPFSPSSASVTVRGLRAGGVGIAERLRPGGVI
MSMEG_4426|M.smegmatis_MC2_155 ----MDDFVRTGLAAHGD--------------------------------
Mvan_5001|M.vanbaalenii_PYR-1 ----LDELIRTALTAHGD--------------------------------
TH_3570|M.thermoresistible__bu ----FADLARTVLAHQHR--------------------------------
MAB_3697|M.abscessus_ATCC_1997 ----YAVAVADELEHPAH--------------------------------
MAV_1850|M.avium_104 -----KGTLRVGFLGRDK--------------------------------
:
MMAR_3024|M.marinum_M QREIAMRTVAVFAHRLYGAITSAHFMAETVPFAKPAMIVSNSGFFGPSMG
MUL_2265|M.ulcerans_Agy99 QREIAMRTVAVFAHRLYGAITSAHFMAETVPFAKPAMIVSNSGFFGPSMG
MSMEG_4426|M.smegmatis_MC2_155 --------------------------------QRRVVTDPDAPYFGAVID
Mvan_5001|M.vanbaalenii_PYR-1 --------------------------------PRTVVADAAARYWGAELG
TH_3570|M.thermoresistible__bu --------------------------------RTPVVIDPQATYFGTRID
MAB_3697|M.abscessus_ATCC_1997 --------------------------------RRERFTVAN---------
MAV_1850|M.avium_104 --------------------------------VGSVMSRADIAAF-----
. .
MMAR_3024|M.marinum_M SLPIFGEERPPAESSFVRRQLRTVRNIGVFGVNLVGLSAGSALDTNDFIA
MUL_2265|M.ulcerans_Agy99 SLPIFGEERPPAESSFVRRQLCTVRNIGVFGVNLVGLSAGSALDTNDFIA
MSMEG_4426|M.smegmatis_MC2_155 -----------------DDTLAPNENALIFSTRYADWIDAHVQKKYLADG
Mvan_5001|M.vanbaalenii_PYR-1 -----------------ERSLVPDGDALLFDTRFEGWILETLTTS-----
TH_3570|M.thermoresistible__bu -----------------DTSLVTGAGAVIAGTPLAAVLAPPASD------
MAB_3697|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_1850|M.avium_104 --------------------LVAQLDDETFIRAAPAISN-----------
MMAR_3024|M.marinum_M DVDRLEQLAGGDVTTLDDRRLLSLILLARDHVVHGWVLASGSFMLCAAFN
MUL_2265|M.ulcerans_Agy99 DVDRLEQLAGGDVTTLDDRRLLSLILLARDHVVHGWVLASGSFMLCAAFN
MSMEG_4426|M.smegmatis_MC2_155 SLPSLRR-------------------------------------------
Mvan_5001|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_3570|M.thermoresistible__bu --------------------------------------------------
MAB_3697|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_1850|M.avium_104 --------------------------------------------------
MMAR_3024|M.marinum_M VLLRAVSGRDTAPAAGPELVSARSVEAVQRLVAAARHDEAVIRLLSEPGD
MUL_2265|M.ulcerans_Agy99 VLLRAVSGRDTAPAAGPELVSARSVEAVQRLVDAARHDEAVIRLLSEPGD
MSMEG_4426|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_5001|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_3570|M.thermoresistible__bu --------------------------------------------------
MAB_3697|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_1850|M.avium_104 --------------------------------------------------
MMAR_3024|M.marinum_M RLGKLAVAAPHFYDAVRQELSLIGHRGPAEVEMMSTSYADNPELLVGMVA
MUL_2265|M.ulcerans_Agy99 RLGKLAVAAPHFYDAVRQELSLIGHRGPAEVEMMSTSYADNPELLVGMVA
MSMEG_4426|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_5001|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_3570|M.thermoresistible__bu --------------------------------------------------
MAB_3697|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_1850|M.avium_104 --------------------------------------------------
MMAR_3024|M.marinum_M KTLSTSSVPQPPQPSIPLQAKPIAVLAARQLRDREARRDKMVRAIWVLRA
MUL_2265|M.ulcerans_Agy99 KTLSTSSVPQPPQPSIPLQAKPIAVLAARQLRDREARRDKMVRAIWVLRA
MSMEG_4426|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_5001|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_3570|M.thermoresistible__bu --------------------------------------------------
MAB_3697|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_1850|M.avium_104 --------------------------------------------------
MMAR_3024|M.marinum_M LLREHGRRLAEAGVLHASDDVFYLLVDELDALPADVAELVARRRAEQRRL
MUL_2265|M.ulcerans_Agy99 LLREHGRRLAEAGVLHASDDVFYLLVDEVDALPADVAELVARRRAEQRRL
MSMEG_4426|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_5001|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_3570|M.thermoresistible__bu --------------------------------------------------
MAB_3697|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_1850|M.avium_104 --------------------------------------------------
MMAR_3024|M.marinum_M TAVVPPTVFSGKWEPSTASAAALTAGGTLRGVGVCGGRVRGRVRIVRPET
MUL_2265|M.ulcerans_Agy99 TAVVPPTVFSGKWEPSTASAAALTAEGTLRGVGVCGGRVRGRVRIVRPET
MSMEG_4426|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_5001|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_3570|M.thermoresistible__bu --------------------------------------------------
MAB_3697|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_1850|M.avium_104 --------------------------------------------------
MMAR_3024|M.marinum_M IDELEPGEILVAEVTDVGYTAAFCYAAAVVTELGGPMSHAAVVAREFGFP
MUL_2265|M.ulcerans_Agy99 IDELEPGEILVAEVTDVGYTAAFCYAAAVVTELGGPMSHAAVVAREFGFP
MSMEG_4426|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_5001|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_3570|M.thermoresistible__bu --------------------------------------------------
MAB_3697|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_1850|M.avium_104 --------------------------------------------------
MMAR_3024|M.marinum_M CVVDAQGATRFLPPGALIEVDGTTGEIQVLELAAEGDSSVTQSDPADLA
MUL_2265|M.ulcerans_Agy99 CVVDAQGATRFLPPGALIEVDGTTGEIQVLELAAEGDSSVTQSDPADLA
MSMEG_4426|M.smegmatis_MC2_155 -------------------------------------------------
Mvan_5001|M.vanbaalenii_PYR-1 -------------------------------------------------
TH_3570|M.thermoresistible__bu -------------------------------------------------
MAB_3697|M.abscessus_ATCC_1997 -------------------------------------------------
MAV_1850|M.avium_104 -------------------------------------------------