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KIVVIGGRGLIGAKVAAKLGAQGHDVTAASRRSGVDALTGEGLAAAVAGADVVVDVSGSPVFDDDPVMRF FVTTTANLLSAEWQAGVSHHVVLSVVGAQSMPDSGYNTAKAAQENLIRDSGRPYTIVRATPFYEFAVGLA DSATDGDVVRLPHASFRPIAADDVATAVACAALGRPVNGVTEIAGPEVIGMDDFVRTGLAAHGDQRRVVT DPDAPYFGAVIDDDTLAPNENALIFSTRYADWIDAHVQKKYLADGSLPSLRR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4426 | - | - | 100% (263) | secreted protein |
| M. smegmatis MC2 155 | MSMEG_2353 | - | 2e-64 | 50.41% (244) | secreted protein |
| M. smegmatis MC2 155 | MSMEG_4056 | - | 4e-48 | 42.11% (247) | hypothetical protein MSMEG_4056 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3360c | - | 5e-63 | 50.41% (244) | hypothetical protein MAB_3360c |
| M. marinum M | MMAR_4766 | - | 5e-82 | 61.85% (249) | hypothetical protein MMAR_4766 |
| M. avium 104 | MAV_4078 | - | 3e-20 | 32.70% (211) | hypothetical protein MAV_4078 |
| M. thermoresistible (build 8) | TH_4498 | - | 2e-66 | 53.88% (245) | PUTATIVE NmrA family protein |
| M. ulcerans Agy99 | MUL_2265 | - | 6e-05 | 26.28% (156) | hypothetical protein MUL_2265 |
| M. vanbaalenii PYR-1 | Mvan_5001 | - | 2e-71 | 55.51% (245) | NmrA family protein |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_4426|M.smegmatis_MC2_155 ----MKIVVIGGRGLIGAKVAAKLGAQGHDVTAASRRS-----------G
MMAR_4766|M.marinum_M ----MKILVIGGSGLIGSQVVAQLTGLAHQAVAASPRS-----------G
TH_4498|M.thermoresistible__bu ----MRIVVIGGTGRIGAQVVTGLVEHGHRAVAAAPST-----------G
Mvan_5001|M.vanbaalenii_PYR-1 ----MLIVVIGGTGLIGSKLIRQLSEHGHRAVAAAPST-----------G
MAB_3360c|M.abscessus_ATCC_199 ----MKITVVGATGQIGSRVVSLLIADGHDVVAASLSS-----------G
MAV_4078|M.avium_104 MRALTTIAVIGATGTAGSRVVARLRPRDVAVVEISRAQ-----------G
MUL_2265|M.ulcerans_Agy99 ----MRVAVTGAGGVLGRGLASRLLSQGHEVVGMSRRRPDSWPSQADFVA
: * *. * * : * .. : .
MSMEG_4426|M.smegmatis_MC2_155 VDALTGEGLAAAVAGADVVVDVSG--SPVFDDDPVMRFFVTTTANLLSAE
MMAR_4766|M.marinum_M VNALTGEGLADAVAGADAVVDVSN--SPSFADDDVLHFFTTSTKNLLAAE
TH_4498|M.thermoresistible__bu VDAFTGEGLRTALTGADVVVDVSN--SPTFDDAAAQEFFRVSTANLLAAE
Mvan_5001|M.vanbaalenii_PYR-1 VDTVTGDGLADVLAGADVVVDVSN--SPSFDDDAALEFFEKSTGNLLAAE
MAB_3360c|M.abscessus_ATCC_199 ANVLTGEGLVDALTGSAVVIDVVN--SPSFEDGPVMDFFTASARNLVDAA
MAV_4078|M.avium_104 VDVFDAPGLTRALEGVDVVIDVSNP-VPPDGRSDIRQTLATAARNIMGAC
MUL_2265|M.ulcerans_Agy99 GDIRDAAAVRRAITGADVVAHCAWARNPGPDGRISQQINIDGTRNVLDAM
: . .: .: * .* . * : *:: *
MSMEG_4426|M.smegmatis_MC2_155 WQAGVSHHVVLS-----------VVGAQSMP--DSGYNTAKAAQENLIRD
MMAR_4766|M.marinum_M QTAGVRHHVALS-----------IVGTDRVP--NSGYLRAKCAQEKLIKE
TH_4498|M.thermoresistible__bu AEAGASHHVALS-----------VVGTDALAR-QSGYFQAKLLQENLIGA
Mvan_5001|M.vanbaalenii_PYR-1 AQAGVGHHVALS-----------VVNTDQLAE-QSGYFRAKALQERLIRQ
MAB_3360c|M.abscessus_ATCC_199 KATGVGHYVALS-----------IVGADGLP--ESGYMRAKVAQEKIIVG
MAV_4078|M.avium_104 ATQEVQRLVVLT-----------IAGIEDPVFDEFPYYQAKREAKEILLD
MUL_2265|M.ulcerans_Agy99 AACGTGRIVFPSSPHVYRPGLPMPATEHGAVAPASAEGRHKAGVEQMLQE
. : * : . . * :.::
MSMEG_4426|M.smegmatis_MC2_155 SGRPYTIVRATPFY-----EFAVGLADSATDGD--------VVRLPH-AS
MMAR_4766|M.marinum_M SDLPYSIVRATQFF-----EFVIGIADSATDGD--------TVRLSHTAA
TH_4498|M.thermoresistible__bu GPVPFTIVRATQFF-----EFLATIADSATLNG--------VVRLPD-VL
Mvan_5001|M.vanbaalenii_PYR-1 SPVPYTIVHATQFY-----EFVKGIADAATDGD--------IVRLAP-VL
MAB_3360c|M.abscessus_ATCC_199 SGLPYTIVRATQFQ-----EFAEAITDTLVVGD--------EVRVPD-AR
MAV_4078|M.avium_104 GPVPTTVVKSTQWY-----EFATNHDAVSCDDN--------EVIVED-WL
MUL_2265|M.ulcerans_Agy99 SGAQWVAVRSALIVGRNIDNWVRRLFALPAFPDGSADDVLQVVHLDDVLR
. *::: :: . * :
MSMEG_4426|M.smegmatis_MC2_155 FRPIAADDVATAVACAALGRPVNGVTEIAG--------------------
MMAR_4766|M.marinum_M IQPIAASDVATGVTRAAISDPLNGTTNIAG--------------------
TH_4498|M.thermoresistible__bu IQPMATADVAEAVAVAAVSPPVNGIVEVGG--------------------
Mvan_5001|M.vanbaalenii_PYR-1 IQPMAAADVAEAMAIAAVGKPHNRIVEVAG--------------------
MAB_3360c|M.abscessus_ATCC_199 IQLIAVDDVSTQVAHAAAAAPRNGIINIGG--------------------
MAV_4078|M.avium_104 IQPIAADTVADVLVETALAQTHT-PRTITG--------------------
MUL_2265|M.ulcerans_Agy99 LLTRAVSDVGAGTGPVNLAAPGLPTLREIATALRRPILPVGAALRRIGSV
: *. *. . . . .
MSMEG_4426|M.smegmatis_MC2_155 ------------------------PEVIGMDDFVRTGLAAHGDQ---RRV
MMAR_4766|M.marinum_M ------------------------PDKFGMDDFVRMGLAAHGDS---RQV
TH_4498|M.thermoresistible__bu ------------------------PAQYRLPELIRTALTAHGDT---REV
Mvan_5001|M.vanbaalenii_PYR-1 ------------------------PQLYRLDELIRTALTAHGDP---RTV
MAB_3360c|M.abscessus_ATCC_199 ------------------------PEKFSFADMAGAVLAARGDD---RPV
MAV_4078|M.avium_104 ------------------------PDAIRLPELTSKLLVRQGDRRAVRSV
MUL_2265|M.ulcerans_Agy99 AEFQLVQGVPVMDTARLHDEWKFQPAFTAEESVEDFALAVRGRVSLGRRV
* .. *. :* * *
MSMEG_4426|M.smegmatis_MC2_155 VTDPDAPYFGAVIDDDTLAPN---------------ENALIFSTRYADWI
MMAR_4766|M.marinum_M RTDPNARYFGAVLDGHSIVPTD-------------GEDVTIYPTHFSDWL
TH_4498|M.thermoresistible__bu LGDPNARYWGVDIDERTLVPG---------------DAAPDFDVRFEDWL
Mvan_5001|M.vanbaalenii_PYR-1 VADAAARYWGAELGERSLVPD---------------GDALLFDTRFEGWI
MAB_3360c|M.abscessus_ATCC_199 VVDSGATYFGTPVDDFSLVTG---------------DDGVLTQTRFADWM
MAV_4078|M.avium_104 EPAVSALGAGALLASGHAVVVG-------------PDVDTWLQTLAPPGG
MUL_2265|M.ulcerans_Agy99 VSLPWRLANIQDLPAIDASAQDGVVPRLAGPEGVNGEFDTPIDPRFPTFL
:
MSMEG_4426|M.smegmatis_MC2_155 DAHVQKKYLADGSLPSLRR-------------------------------
MMAR_4766|M.marinum_M AAG-----------------------------------------------
TH_4498|M.thermoresistible__bu LASAAENRR-----------------------------------------
Mvan_5001|M.vanbaalenii_PYR-1 LETLTTS-------------------------------------------
MAB_3360c|M.abscessus_ATCC_199 ARR-----------------------------------------------
MAV_4078|M.avium_104 DGHRGRDGDGHRGADGDHRGADGDGKPRRG--------------------
MUL_2265|M.ulcerans_Agy99 ATNLSEALPGPFSPSSASVTVRGLRAGGVGIAERLRPGGVIQREIAMRTV
MSMEG_4426|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_4766|M.marinum_M --------------------------------------------------
TH_4498|M.thermoresistible__bu --------------------------------------------------
Mvan_5001|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3360c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4078|M.avium_104 --------------------------------------------------
MUL_2265|M.ulcerans_Agy99 AVFAHRLYGAITSAHFMAETVPFAKPAMIVSNSGFFGPSMGSLPIFGEER
MSMEG_4426|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_4766|M.marinum_M --------------------------------------------------
TH_4498|M.thermoresistible__bu --------------------------------------------------
Mvan_5001|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3360c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4078|M.avium_104 --------------------------------------------------
MUL_2265|M.ulcerans_Agy99 PPAESSFVRRQLCTVRNIGVFGVNLVGLSAGSALDTNDFIADVDRLEQLA
MSMEG_4426|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_4766|M.marinum_M --------------------------------------------------
TH_4498|M.thermoresistible__bu --------------------------------------------------
Mvan_5001|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3360c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4078|M.avium_104 --------------------------------------------------
MUL_2265|M.ulcerans_Agy99 GGDVTTLDDRRLLSLILLARDHVVHGWVLASGSFMLCAAFNVLLRAVSGR
MSMEG_4426|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_4766|M.marinum_M --------------------------------------------------
TH_4498|M.thermoresistible__bu --------------------------------------------------
Mvan_5001|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3360c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4078|M.avium_104 --------------------------------------------------
MUL_2265|M.ulcerans_Agy99 DTAPAAGPELVSARSVEAVQRLVDAARHDEAVIRLLSEPGDRLGKLAVAA
MSMEG_4426|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_4766|M.marinum_M --------------------------------------------------
TH_4498|M.thermoresistible__bu --------------------------------------------------
Mvan_5001|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3360c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4078|M.avium_104 --------------------------------------------------
MUL_2265|M.ulcerans_Agy99 PHFYDAVRQELSLIGHRGPAEVEMMSTSYADNPELLVGMVAKTLSTSSVP
MSMEG_4426|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_4766|M.marinum_M --------------------------------------------------
TH_4498|M.thermoresistible__bu --------------------------------------------------
Mvan_5001|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3360c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4078|M.avium_104 --------------------------------------------------
MUL_2265|M.ulcerans_Agy99 QPPQPSIPLQAKPIAVLAARQLRDREARRDKMVRAIWVLRALLREHGRRL
MSMEG_4426|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_4766|M.marinum_M --------------------------------------------------
TH_4498|M.thermoresistible__bu --------------------------------------------------
Mvan_5001|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3360c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4078|M.avium_104 --------------------------------------------------
MUL_2265|M.ulcerans_Agy99 AEAGVLHASDDVFYLLVDEVDALPADVAELVARRRAEQRRLTAVVPPTVF
MSMEG_4426|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_4766|M.marinum_M --------------------------------------------------
TH_4498|M.thermoresistible__bu --------------------------------------------------
Mvan_5001|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3360c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4078|M.avium_104 --------------------------------------------------
MUL_2265|M.ulcerans_Agy99 SGKWEPSTASAAALTAEGTLRGVGVCGGRVRGRVRIVRPETIDELEPGEI
MSMEG_4426|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_4766|M.marinum_M --------------------------------------------------
TH_4498|M.thermoresistible__bu --------------------------------------------------
Mvan_5001|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3360c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4078|M.avium_104 --------------------------------------------------
MUL_2265|M.ulcerans_Agy99 LVAEVTDVGYTAAFCYAAAVVTELGGPMSHAAVVAREFGFPCVVDAQGAT
MSMEG_4426|M.smegmatis_MC2_155 ----------------------------------------
MMAR_4766|M.marinum_M ----------------------------------------
TH_4498|M.thermoresistible__bu ----------------------------------------
Mvan_5001|M.vanbaalenii_PYR-1 ----------------------------------------
MAB_3360c|M.abscessus_ATCC_199 ----------------------------------------
MAV_4078|M.avium_104 ----------------------------------------
MUL_2265|M.ulcerans_Agy99 RFLPPGALIEVDGTTGEIQVLELAAEGDSSVTQSDPADLA