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M. abscessus ATCC 19977 MAB_3317c (-)

annotation: peptide synthetase NRP
coordinates: 3355855 - 3363528
length: 2557

SVDPSRTLSSLDLLDDDEHAQLATWGNQAVLKECPDTMPSIPAVFARQVECTPEALALTFDGQSMTYREL
DEAANRLSHLLVGAGAGPGQFVALLFPRSTEAIVAILAVLKSGAAYLPIDPALPTTRIEFMLTDAAPVAA
VTTAVLAHRLHGLGVPVLDVDDPAVCTQPCTAPPMPSPEDLAHLIYTSGTTGVPKGVAVTQRNVVQLFDR
LDIGVELAPGQVWTQFHSYAFDFSVWEIWGALLHGGRLVVVPDSVARTPEDFHDLLMGERVTVMSQTPSA
AGVLSPDGLEATALVIGAEPCPPELVDRWAPGRVMVNVYGPTETTMWACKSAPLSAGSEGHGVPIGSPVA
HAASFVLDRWLRPVPDGVIGELYLAGAGVGSGYWRRTALTGARFVACPFGMPGDRMYRTGDLVSWGADGQ
LQYLGRADEQIKIRGYRIELGEIQAALVRLDGVRQAAVIVREDRPGDKRIVGYITGGADPVGARAALAEQ
LPAYMVPVAVVALQTLPVTVNGKLDKQGLPAPEYSGVDFRAPSTPVEEALAGIYAQVLGVDRVGADDSFF
DLGGDSILAMQVAGRARAAGVLCRPRDIFVEQTVARLSRVVTLAENEIRNVDDGIGPVAPTPIMHWLHSV
PGPVERFNQTVVLQAPAGAAEADIVVLLQALLDHHGTLRLHAENNDGGWSLRVPEKGAVDARACIRTVEA
LSDEAVEAACSRLDPGAGAMLSALWAPAEGKLALVIHHLAVDGVSWRILLEDLNVAWAQRRSGLDVALSG
AGTSFARWASLLREQALSAGVVESADVWRSVSAVPPALPVVRPGVDTYAVAGTLSVALDADVTRMLLGEV
PAAFHAGVQDVLLIAFALAWNEFLGAGGAPIGIDLEGHGRAEELAADIDLSRTVGWFTAKYPAALSVGDL
SWAQVSGGDSALGLVVKSVKEQLRGLPDPLSYGLLRYLNPEVALPHSDSAIGFNYLGRLGAGATEASEDI
WTISHEGLSWTSASSTVPMPMAHTVELNAGILESSVESGPRLQAVWTWAPSLVDAIQVQRLSRLWFEALV
GICTHVRTGGGGLTPSDILPARLTQGELDELTKCLRVADVLPLTPVQQGLLFHSAIAARADSAAAGTALA
DIYAVQLNLTMTGAVDPRRLYNAMHAVVKRHPNLVARFCTRFGEPVQVIPADPMICWQQTEFESTEELER
FCAAERVAACDLAGKSTFRSALVRTGGDKHRFILTFHHVVIDGWSLPILLREIFAIYFGQALAPAPSYRG
FVSWLAQQDREAARAAWRKALEGFEAPTLVAPRSVPGSRGVASYRISAETTRALGDLARSQHTTVSTVLR
AAWAQLLMVQTGAHDVAFGTVVSGRPALLTGADSVVGLLINTVPVRARATATTTVADLLRDMQSIHNDLL
EHEHLALNEIHHLAGHDRLFDTLFLYENYPVDVSTFMGTHELGITEFTSREYNHYPLSVMALPGHELGIR
IEYDTDAFDVADIGALVQRLRRILGAMTAAPARRVLSIDVLEVAERGRLDSWGNRAVLACATAASSSIPE
VFARQVDRAPQAVALTFQGRSMTYRELDHAANRLAQLLASRGAGPGESIALMVPRSDDAIVALLAVLKTG
AAYLPIDPAVPVARLEFMLADAAPIAVATTAELRQRLAGSSIPVLVIDEHVVDEPAAVSLQAPRPDDIAY
TIYTSGTTGTPKGVAVTHRNVTQLLETLPVGLPAGPGQVWSQWHSMVFDVSVWEVWGALLHGARLMVVPE
AVAGSPQHLHDLLVTEKVSVLHQTPSAIGMLDWDGVDDMAVVVAGEPCPPEVVDRWAPGRLMLNAYGPTE
ATIYAAISMPLSPKTSPVPIGSPVRGGATFVLDGWLRPVPPGVVGELYLAGSGVGVGYVHRSGLTGSRFV
ACPFGRPGVRMYRTGDLARYSEDGQLQYLGRTDEQVKIRGYRIELDEIRSALAELDGVEHAAVIVREDRP
GDKRLVGYVTGTADPTMLRTLLGERLPQYMVPAAVVAVDAIPLTINGKLDKRSLPAPVYHDAARYREPVS
PVERTIADIYAHTLGLERIGVEDSFFDVGGDSISAMRVVAAINTALDVDLEVWTIFDAPSVRSLSARLNG
AVSASPIAESSRTSCASVHGRGVTQVMATDLTLDKFVDVTALIANRSRRHPRGDVREILLTGATGFLGRH
LVLHWLREMEHAGGTLTCLVRGSSHEEARSRLEKSFDSGDPGLMALFRRLAADRLKVVAGDKGEPHLGLE
PQTWEHLAESVDLVVDSAAFVNSVLPYEELFRPNVVGTAELIRLALTAKLKPYTFVSTSDVGRQVDRSKF
TEVADIREISPSRVLDAGYANGYANSKWAAEVLLREAHDMFGLPVAVFRSSMVMADTSYAGQLNMADTIS
RMVLSIMATGVAPESFYQLDMHGNRQRAHFDGLPVEFVAEAIATLGSQATDGFETYHVMNPHDDGVGIDQ
FVDWLVEAGHPIERVGNFGVWLQRFEAGLRALPNPQRQNSVLQMLMVLKQHGQLRAPAPTCGSYAPADRF
QAAVRRAKIGSDQDIPHISAPIILKYVTDLQMLGLL*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. abscessus ATCC 19977MAB_3317c--100% (2557)peptide synthetase NRP
M. abscessus ATCC 19977MAB_4098c-0.065.51% (2589) peptide synthetase NRP
M. abscessus ATCC 19977MAB_4099c-0.061.49% (2114) non-ribosomal peptide synthetase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0104nrp0.051.41% (1488) peptide synthetase
M. gilvum PYR-GCKMflv_2697-1e-14934.41% (1119) amino acid adenylation domain-containing protein
M. tuberculosis H37RvRv0101nrp0.051.41% (1488) peptide synthetase
M. leprae Br4923MLBr_00484fadD91e-16044.09% (753) putative acyl-CoA synthetase
M. marinum MMMAR_0099-0.057.51% (2151) non-ribosomal peptide synthetase
M. avium 104MAV_3243-0.064.54% (2572) linear gramicidin synthetase subunit B
M. smegmatis MC2 155MSMEG_0402-0.065.28% (2578) linear gramicidin synthetase subunit D
M. thermoresistible (build 8)TH_3730-0.060.34% (2171) PUTATIVE linear gramicidin synthetase subunit D
M. ulcerans Agy99MUL_1722-1e-16737.60% (1117) fatty-acid-CoA ligase FadD9
M. vanbaalenii PYR-1Mvan_2578-1e-16536.61% (1120) thioester reductase domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


MAV_3243|M.avium_104                --------------------------------------------------
MSMEG_0402|M.smegmatis_MC2_155      --------------------------------------------------
TH_3730|M.thermoresistible__bu      --------------------------------------------------
MAB_3317c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_2697|M.gilvum_PYR-GCK          --MTAAKTGAIADVMALSPLQQGLYSLTAMS--DGDDPYLIGMSADITGA
MMAR_0099|M.marinum_M               MTQPTKPVVDIEDVMTLSPLQLGLFALAMASGAASDDPYTVALGIDVHGS
Mb0104|M.bovis_AF2122/97            --------------------------------------------------
Rv0101|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_1722|M.ulcerans_Agy99           --------------------------------------------------
Mvan_2578|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00484|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MAV_3243|M.avium_104                --------------------------------------------------
MSMEG_0402|M.smegmatis_MC2_155      --------------------------------------------------
TH_3730|M.thermoresistible__bu      --------------------------------------------------
MAB_3317c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_2697|M.gilvum_PYR-GCK          LDVSLLHDCAAAVLARHPNLRAGFFQGDLKRPVQVIPEKVEVLWRHVRCD
MMAR_0099|M.marinum_M               LDVGLLRSCALAMLKRHPNLRARFLGRGLPHPVQVVPSEVQLEWARVEAT
Mb0104|M.bovis_AF2122/97            --------------------------------------------------
Rv0101|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_1722|M.ulcerans_Agy99           --------------------------------------------------
Mvan_2578|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00484|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MAV_3243|M.avium_104                --------------------------------------------------
MSMEG_0402|M.smegmatis_MC2_155      --------------------------------------------------
TH_3730|M.thermoresistible__bu      --------------------------------------------------
MAB_3317c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_2697|M.gilvum_PYR-GCK          GTEVEPLEREERARRFDLGRGPAMRFLLLETGQQRWRFVITAHHIVIDGW
MMAR_0099|M.marinum_M               AETAGALEAQERNRGFDLEMGPAIRFLLIELPGDRWRFLITAHHIVIGGW
Mb0104|M.bovis_AF2122/97            -----------------------MHRVRLSRSQRNLYNGVRQDNNPALYL
Rv0101|M.tuberculosis_H37Rv         -----------------------MHRVRLSRSQRNLYNGVRQDNNPALYL
MUL_1722|M.ulcerans_Agy99           --------------------------------------------------
Mvan_2578|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00484|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MAV_3243|M.avium_104                --------------------------------------------------
MSMEG_0402|M.smegmatis_MC2_155      --------------------------------------------------
TH_3730|M.thermoresistible__bu      --------------------------------------------------
MAB_3317c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_2697|M.gilvum_PYR-GCK          SLSLLVSELLALYRAAGNTSALPDAPRPYRDYIGWLAARDQDHARSLWRA
MMAR_0099|M.marinum_M               SIALFVDELLTLYEADCNIDTLPAQPRPYRDYIGWLERCDVEQGQRQWRE
Mb0104|M.bovis_AF2122/97            IGKSYRFRRLELARFLAALHATVLDNPVQLCVLENSGADYPDLVPRLRFG
Rv0101|M.tuberculosis_H37Rv         IGKSYRFRRLELARFLAALHATVLDNPVQLCVLENSGADYPDLVPRLRFG
MUL_1722|M.ulcerans_Agy99           --------------------------------------------------
Mvan_2578|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00484|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MAV_3243|M.avium_104                --------------------------------------------------
MSMEG_0402|M.smegmatis_MC2_155      --------------------------------------------------
TH_3730|M.thermoresistible__bu      --------------------------------------------------
MAB_3317c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_2697|M.gilvum_PYR-GCK          HLADLDGPTLLAPALGAATIG-DGLPGMVELTADPSITEAVVDAARARGV
MMAR_0099|M.marinum_M               HLAGLAAPTLLAAPLGSSGVQPDSLPKRAELTLDEGATTSLVDGARSRGV
Mb0104|M.bovis_AF2122/97            DIVRVGSADEHLQSTWCSGILGKPLVRHTVHTDPNGYVTGLDVHTHHILL
Rv0101|M.tuberculosis_H37Rv         DIVRVGSADEHLQSTWCSGILGKPLVRHTVHTDPNGYVTGLDVHTHHILL
MUL_1722|M.ulcerans_Agy99           --------------------------------------------------
Mvan_2578|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00484|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MAV_3243|M.avium_104                --------------------------------------------------
MSMEG_0402|M.smegmatis_MC2_155      --------------------------------------------------
TH_3730|M.thermoresistible__bu      --------------------------------------------------
MAB_3317c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_2697|M.gilvum_PYR-GCK          TVNSLVQLAWALTLSSLTDRDDITFGVTVSGRPDDLAGVESMIGLFVNTV
MMAR_0099|M.marinum_M               TVNTLTQLAWALMLSMLTDRRDVVFGVTVSSRPAELARVESMVGLFVNTV
Mb0104|M.bovis_AF2122/97            DGGATGTIEADLARYLTTDPAGETPSVGAGLAKLREAHRRETAKVEESRG
Rv0101|M.tuberculosis_H37Rv         DGGATGTIEADLARYLTTDPAGETPSVGAGLAKLREAHRRETAKVEESRG
MUL_1722|M.ulcerans_Agy99           --------------------------------------------------
Mvan_2578|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00484|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MAV_3243|M.avium_104                --------MTVG-AGRRLLSIDLLDGGEHDRLDEWGNRAILTK-------
MSMEG_0402|M.smegmatis_MC2_155      --------MTAEPSTRTLLSFDLLDEDEHDQIEVWGNRAVLTD-------
TH_3730|M.thermoresistible__bu      --------------------------------------------------
MAB_3317c|M.abscessus_ATCC_199      ---------MSVDPSRTLSSLDLLDDDEHAQLATWGNQAVLKE-------
Mflv_2697|M.gilvum_PYR-GCK          PLRVRLDPALTAGAQCRALQQDAATLRDHSYLGHAELRALAGVGELFDTL
MMAR_0099|M.marinum_M               PLRVRLDPKTTVAQQCALIQRDAARLREHAYLSHSQIRALAGMGELFDTL
Mb0104|M.bovis_AF2122/97            RLSAVVQRELADEAYHGGHGHSVSDAPGTAAKGVLHESATICGNAFDAIL
Rv0101|M.tuberculosis_H37Rv         RLSAVVQRELADEAYHGGHGHSVSDAPGTAAKGVLHESATICGNAFDAIL
MUL_1722|M.ulcerans_Agy99           --------------------------------------------------
Mvan_2578|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00484|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MAV_3243|M.avium_104                ---------------------------PVKAPASIPGMFAAQVARSAEAV
MSMEG_0402|M.smegmatis_MC2_155      ---------------------------PGPTPVTIPALFAEQVVRAPDAV
TH_3730|M.thermoresistible__bu      --------------------------------------------------
MAB_3317c|M.abscessus_ATCC_199      ---------------------------CPDTMPSIPAVFARQVECTPEAL
Mflv_2697|M.gilvum_PYR-GCK          LVYENFPPGAVAGAGTLEAAGATFTPVALQSLAHFPVTIAAHLTDGRLTV
MMAR_0099|M.marinum_M               LVFQNFPSLGLADGKARAVGAARFDSLTVQSPTHFPVCITAELTDARLSL
Mb0104|M.bovis_AF2122/97            TLSEAQRVPLNVLVAAAAVAVDASLRQNTETLLVHTVDNRFGDSDLNVAT
Rv0101|M.tuberculosis_H37Rv         TLSEAQRVPLNVLVAAAAVAVDASLRQNTETLLVHTVDNRFGDSDLNVAT
MUL_1722|M.ulcerans_Agy99           --------------------------------------------------
Mvan_2578|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00484|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MAV_3243|M.avium_104                ALSFEG--------------------------------------------
MSMEG_0402|M.smegmatis_MC2_155      ALVSGD--------------------------------------------
TH_3730|M.thermoresistible__bu      --------------------------------------------------
MAB_3317c|M.abscessus_ATCC_199      ALTFDG--------------------------------------------
Mflv_2697|M.gilvum_PYR-GCK          LVEAKDGALGQITPRALGTRLLATVSRIVEGWDRPLREISISPD------
MMAR_0099|M.marinum_M               SIATNANAFGDITESALGDRLVAVLQRLLPMWDRPLRDVSMLLDGQTDGD
Mb0104|M.bovis_AF2122/97            CLVN----------------------------------------------
Rv0101|M.tuberculosis_H37Rv         CLVN----------------------------------------------
MUL_1722|M.ulcerans_Agy99           --------------------------------------------------
Mvan_2578|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00484|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MAV_3243|M.avium_104                --------------------------------------------------
MSMEG_0402|M.smegmatis_MC2_155      --------------------------------------------------
TH_3730|M.thermoresistible__bu      --------------------------------------------------
MAB_3317c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_2697|M.gilvum_PYR-GCK          ----------------------DHPVPVP---------------------
MMAR_0099|M.marinum_M               TAVSEHARLDVVGNRAVLAEPLVEPVSVPGLFAAQVASRAEVTALVCGDR
Mb0104|M.bovis_AF2122/97            --------------------------------------------------
Rv0101|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_1722|M.ulcerans_Agy99           --------------------------------------------------
Mvan_2578|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00484|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MAV_3243|M.avium_104                --------------------------------------------------
MSMEG_0402|M.smegmatis_MC2_155      --------------------------------------------------
TH_3730|M.thermoresistible__bu      --------------------------------------------------
MAB_3317c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_2697|M.gilvum_PYR-GCK          --------------------------------------------------
MMAR_0099|M.marinum_M               SLTYRELDRAANRLAHLLVDQGVGPGDVVGLLLERSVEAVIAILAVLKSG
Mb0104|M.bovis_AF2122/97            --------------------------------------------------
Rv0101|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_1722|M.ulcerans_Agy99           --------------------------------------------------
Mvan_2578|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00484|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MAV_3243|M.avium_104                --------------------------------------------------
MSMEG_0402|M.smegmatis_MC2_155      --------------------------------------------------
TH_3730|M.thermoresistible__bu      --------------------------------------------------
MAB_3317c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_2697|M.gilvum_PYR-GCK          --------------------------------------------------
MMAR_0099|M.marinum_M               AAYLAIDVNHPDGRIGFMIEDAAPVAVITTAGLAQRLAGYPVAVIDIDDP
Mb0104|M.bovis_AF2122/97            --------------------------------------------------
Rv0101|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_1722|M.ulcerans_Agy99           --------------------------------------------------
Mvan_2578|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00484|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MAV_3243|M.avium_104                --------------------------------------------------
MSMEG_0402|M.smegmatis_MC2_155      --------------------------------------------------
TH_3730|M.thermoresistible__bu      --------------------------------------------------
MAB_3317c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_2697|M.gilvum_PYR-GCK          ------------------------------------------------VS
MMAR_0099|M.marinum_M               AIATCYPGYGLPFPSADNIAYLIYTSGTTGKPKGVGITHHNITQLFTSVA
Mb0104|M.bovis_AF2122/97            --------------------------------------------------
Rv0101|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_1722|M.ulcerans_Agy99           --------------------------------------------------
Mvan_2578|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00484|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MAV_3243|M.avium_104                --------------------------------------------------
MSMEG_0402|M.smegmatis_MC2_155      --------------------------------------------------
TH_3730|M.thermoresistible__bu      --------------------------------------------------
MAB_3317c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_2697|M.gilvum_PYR-GCK          EAAPTPSP------------------------------------------
MMAR_0099|M.marinum_M               ATGFTPAPGQIWTQCHSYAFDYSVWEMWGALLHGGRLVVVPELVTRSAAE
Mb0104|M.bovis_AF2122/97            --------------------------------------------------
Rv0101|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_1722|M.ulcerans_Agy99           --------------------------------------------------
Mvan_2578|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00484|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MAV_3243|M.avium_104                --------------------------------------------------
MSMEG_0402|M.smegmatis_MC2_155      --------------------------------------------------
TH_3730|M.thermoresistible__bu      --------------------------------------------------
MAB_3317c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_2697|M.gilvum_PYR-GCK          --------------------------------------------------
MMAR_0099|M.marinum_M               LLALLVTEGVGVLSQTPSAFYALQAEDAAQPQLGRQLCLDAVVFGGEALE
Mb0104|M.bovis_AF2122/97            --------------------------------------------------
Rv0101|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_1722|M.ulcerans_Agy99           --------------------------------------------------
Mvan_2578|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00484|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MAV_3243|M.avium_104                --------------------------------------------------
MSMEG_0402|M.smegmatis_MC2_155      --------------------------------------------------
TH_3730|M.thermoresistible__bu      --------------------------------------------------
MAB_3317c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_2697|M.gilvum_PYR-GCK          ------------------------STGVHTRFTETA--------------
MMAR_0099|M.marinum_M               PARLGPWLANHGRRPRLINMYGITETTVHASFREIVRHDLGFAVSPVGVP
Mb0104|M.bovis_AF2122/97            --------------------------------------------------
Rv0101|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_1722|M.ulcerans_Agy99           --------------------------------------------------
Mvan_2578|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00484|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MAV_3243|M.avium_104                --------------------------------------------------
MSMEG_0402|M.smegmatis_MC2_155      --------------------------------------------------
TH_3730|M.thermoresistible__bu      --------------------------------------------------
MAB_3317c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_2697|M.gilvum_PYR-GCK          --------------------------------------------------
MMAR_0099|M.marinum_M               LANLAFFVLDGWLRPVPVGVAGELYVAGAGVGCGYWRRSGLTASRFVACP
Mb0104|M.bovis_AF2122/97            --------------------------------------------------
Rv0101|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_1722|M.ulcerans_Agy99           --------------------------------------------------
Mvan_2578|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00484|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MAV_3243|M.avium_104                --------------------------------------------------
MSMEG_0402|M.smegmatis_MC2_155      --------------------------------------------------
TH_3730|M.thermoresistible__bu      --------------------------------------------------
MAB_3317c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_2697|M.gilvum_PYR-GCK          --------------------------------------------------
MMAR_0099|M.marinum_M               FGALGARMYRTGDVVRWGPDGQLQYVGRADEQVKIRGYRIELGEVAAALS
Mb0104|M.bovis_AF2122/97            --------------------------------------------------
Rv0101|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_1722|M.ulcerans_Agy99           --------------------------------------------------
Mvan_2578|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00484|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MAV_3243|M.avium_104                --------------------------------------------------
MSMEG_0402|M.smegmatis_MC2_155      --------------------------------------------------
TH_3730|M.thermoresistible__bu      --------------------------------------------------
MAB_3317c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_2697|M.gilvum_PYR-GCK          --------------------------------------------------
MMAR_0099|M.marinum_M               QLDGVDQAVVIAREDRPGDKRLVGYLVGSVDAGQARAALAQALPAYMVPA
Mb0104|M.bovis_AF2122/97            --------------------------------------------------
Rv0101|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_1722|M.ulcerans_Agy99           --------------------------------------------------
Mvan_2578|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00484|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MAV_3243|M.avium_104                --------------------------------------------------
MSMEG_0402|M.smegmatis_MC2_155      --------------------------------------------------
TH_3730|M.thermoresistible__bu      --------------------------------------------------
MAB_3317c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_2697|M.gilvum_PYR-GCK          --------------------------------------------------
MMAR_0099|M.marinum_M               AVVVVDSLPLTVNGKLDIRALPAPQYGATGSYRAPASPVEEVLAGIYAQV
Mb0104|M.bovis_AF2122/97            --------------------------------------------------
Rv0101|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_1722|M.ulcerans_Agy99           --------------------------------------------------
Mvan_2578|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00484|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MAV_3243|M.avium_104                --------------------------------------------------
MSMEG_0402|M.smegmatis_MC2_155      --------------------------------------------------
TH_3730|M.thermoresistible__bu      --------------------------------------------------
MAB_3317c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_2697|M.gilvum_PYR-GCK          --------------------------------------------------
MMAR_0099|M.marinum_M               LGLDRVAVDQSFFDLGGDSLSAMRVVAAINKSLGGDLSVRALFDAPTVAE
Mb0104|M.bovis_AF2122/97            --------------------------------------------------
Rv0101|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_1722|M.ulcerans_Agy99           --------------------------------------------------
Mvan_2578|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00484|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MAV_3243|M.avium_104                --------------------------------------------------
MSMEG_0402|M.smegmatis_MC2_155      --------------------------------------------------
TH_3730|M.thermoresistible__bu      --------------------------------------------------
MAB_3317c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_2697|M.gilvum_PYR-GCK          --------------------------------------------------
MMAR_0099|M.marinum_M               LAPGIGQGSGQWTPLVAGERPAVVPLSFAQQRLWFIDQLQGPSAVYNMAW
Mb0104|M.bovis_AF2122/97            --------------------------------------------------
Rv0101|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_1722|M.ulcerans_Agy99           --------------------------------------------------
Mvan_2578|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00484|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MAV_3243|M.avium_104                --------------------------------------------------
MSMEG_0402|M.smegmatis_MC2_155      --------------------------------------------------
TH_3730|M.thermoresistible__bu      --------------------------------------------------
MAB_3317c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_2697|M.gilvum_PYR-GCK          SARLG---------------------------------------------
MMAR_0099|M.marinum_M               SARLSGELDAAALGAAFADVVGRHESLRTVFRAVAGVAEQLVLGVEQVDV
Mb0104|M.bovis_AF2122/97            --------------------------------------------------
Rv0101|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_1722|M.ulcerans_Agy99           --------------------------------------------------
Mvan_2578|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00484|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MAV_3243|M.avium_104                --------------------------------------------------
MSMEG_0402|M.smegmatis_MC2_155      --------------------------------------------------
TH_3730|M.thermoresistible__bu      --------------------------------------------------
MAB_3317c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_2697|M.gilvum_PYR-GCK          --------------------------------------------------
MMAR_0099|M.marinum_M               RWQIIDAQGWSSRRLAAALEQQARHCFDLTVEIPLRASLFRVTDDEHVLV
Mb0104|M.bovis_AF2122/97            --------------------------------------------------
Rv0101|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_1722|M.ulcerans_Agy99           --------------------------------------------------
Mvan_2578|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00484|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MAV_3243|M.avium_104                --------------------------------------------------
MSMEG_0402|M.smegmatis_MC2_155      --------------------------------------------------
TH_3730|M.thermoresistible__bu      --------------------------------------------------
MAB_3317c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_2697|M.gilvum_PYR-GCK          --------------------------------------------------
MMAR_0099|M.marinum_M               VVAHHIAADGWSLRPLVTDLGVAYASRCAGRAPGWAGLAVQYVDYTLWQR
Mb0104|M.bovis_AF2122/97            --------------------------------------------------
Rv0101|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_1722|M.ulcerans_Agy99           --------------------------------------------------
Mvan_2578|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00484|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MAV_3243|M.avium_104                --------------------------------------------------
MSMEG_0402|M.smegmatis_MC2_155      --------------------------------------------------
TH_3730|M.thermoresistible__bu      --------------------------------------------------
MAB_3317c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_2697|M.gilvum_PYR-GCK          --------------------------------------------------
MMAR_0099|M.marinum_M               TNLGELTDSHSGIAGQLRYWEKALEGMAERLQLPTDRAYPRVADHRGSGV
Mb0104|M.bovis_AF2122/97            --------------------------------------------------
Rv0101|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_1722|M.ulcerans_Agy99           --------------------------------------------------
Mvan_2578|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00484|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MAV_3243|M.avium_104                --------------------------------------------------
MSMEG_0402|M.smegmatis_MC2_155      --------------------------------------------------
TH_3730|M.thermoresistible__bu      --------------------------------------------------
MAB_3317c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_2697|M.gilvum_PYR-GCK          --------------------------------------------------
MMAR_0099|M.marinum_M               DVQWPAQLQQQVARVAREHHATSFMVIQTALAVLLAKLSGSSDVAVGVPV
Mb0104|M.bovis_AF2122/97            --------------------------------------------------
Rv0101|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_1722|M.ulcerans_Agy99           --------------------------------------------------
Mvan_2578|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00484|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MAV_3243|M.avium_104                --------------------------------------------------
MSMEG_0402|M.smegmatis_MC2_155      --------------------------------------------------
TH_3730|M.thermoresistible__bu      --------------------------------------------------
MAB_3317c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_2697|M.gilvum_PYR-GCK          --------------------------------------------------
MMAR_0099|M.marinum_M               AGRGDPALDELVGVFVNTVVLRVQVAGDPTFAQLLAQVRTRSLAAFEHQD
Mb0104|M.bovis_AF2122/97            --------------------------------------------------
Rv0101|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_1722|M.ulcerans_Agy99           --------------------------------------------------
Mvan_2578|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00484|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MAV_3243|M.avium_104                --------------------------------------------------
MSMEG_0402|M.smegmatis_MC2_155      --------------------------------------------------
TH_3730|M.thermoresistible__bu      --------------------------------------------------
MAB_3317c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_2697|M.gilvum_PYR-GCK          ----------------------SVALSWD---------------------
MMAR_0099|M.marinum_M               VPFEVLVERLNPVRSLTHHPLVQVVLAWQNDMSAELVLDGLDVEFAPVHT
Mb0104|M.bovis_AF2122/97            --------------------------------------------------
Rv0101|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_1722|M.ulcerans_Agy99           --------------------------------------------------
Mvan_2578|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00484|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MAV_3243|M.avium_104                --------------------------------------------------
MSMEG_0402|M.smegmatis_MC2_155      --------------------------------------------------
TH_3730|M.thermoresistible__bu      --------------------------------------------------
MAB_3317c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_2697|M.gilvum_PYR-GCK          ------------------------GG------------------------
MMAR_0099|M.marinum_M               QTARMDLVFSLGERFTDTGAPAGIGGGVEFRTDVFDAASIAALIQRLQRV
Mb0104|M.bovis_AF2122/97            --------------------------------------------------
Rv0101|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_1722|M.ulcerans_Agy99           --------------------------------------------------
Mvan_2578|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00484|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MAV_3243|M.avium_104                --------------------------------------------------
MSMEG_0402|M.smegmatis_MC2_155      --------------------------------------------------
TH_3730|M.thermoresistible__bu      --------------------------------------------------
MAB_3317c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_2697|M.gilvum_PYR-GCK          --------------------------------------------------
MMAR_0099|M.marinum_M               VVAMVADPDRRLSSVDLLDAAEHARLDVVGNRAVLAEPLVEPVSVPGLFA
Mb0104|M.bovis_AF2122/97            --------------------------------------------------
Rv0101|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_1722|M.ulcerans_Agy99           --------------------------------------------------
Mvan_2578|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00484|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MAV_3243|M.avium_104                ----------------RSMTYRELDEASNRLAHLLAEQGAAPGECVALLF
MSMEG_0402|M.smegmatis_MC2_155      ----------------RSWTYRELDEASNRLAHVLAEHGAKPGATVAFLI
TH_3730|M.thermoresistible__bu      --------------------------------------------------
MAB_3317c|M.abscessus_ATCC_199      ----------------QSMTYRELDEAANRLSHLLVGAGAGPGQFVALLF
Mflv_2697|M.gilvum_PYR-GCK          -----------------ALTYRQLDEAADRLAAVLTASGVRTETPVAVRL
MMAR_0099|M.marinum_M               AQVASRAEVTALVCEDRSLTYRELDRAANRLAHLLVDQGVGPGDVVGLLL
Mb0104|M.bovis_AF2122/97            ----------------SVAQTVRFPPFASVSDVVRTLDRGYVKAVRRRWL
Rv0101|M.tuberculosis_H37Rv         ----------------SVAQTVRFPPFASVSDVVRTLDRGYVKAVRRRWL
MUL_1722|M.ulcerans_Agy99           --------------------------------------------------
Mvan_2578|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00484|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MAV_3243|M.avium_104                SRSDEAIVSILAVLKTGAAYLPIDPALPAARMEFMLGDATPIAAVTTAGL
MSMEG_0402|M.smegmatis_MC2_155      PRSGEAILSILSVLKTGAAYLPVDPAHPDARIGFMMSDAKPVAALTTADL
TH_3730|M.thermoresistible__bu      --------------------------------------------VTTAEL
MAB_3317c|M.abscessus_ATCC_199      PRSTEAIVAILAVLKSGAAYLPIDPALPTTRIEFMLTDAAPVAAVTTAVL
Mflv_2697|M.gilvum_PYR-GCK          RRGADYVVAMFAVLKAGGAIVPLDPAMPADRIEVILRRAGVTVVVDEDTV
MMAR_0099|M.marinum_M               ERSVEAVIAILAVLKSGAAYLAIDVNHPDGRIGFMIEDAAPVAVITTAGL
Mb0104|M.bovis_AF2122/97            REEHYRRMYLAINRTSHVEALTLNFIREPCAPGLRPFLSEVPIATDIGPV
Rv0101|M.tuberculosis_H37Rv         REEHYRRMYLAINRTSHVEALTLNFIREPCAPGLRPFLSEVPIATDIGPV
MUL_1722|M.ulcerans_Agy99           --------------------------------------------------
Mvan_2578|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00484|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MAV_3243|M.avium_104                RDRLEGFDLPVIDVDEAAAEIERTQPSSALPGPSPDDIAYMIYTSGTTGT
MSMEG_0402|M.smegmatis_MC2_155      RSRLDQYDLAVIDMADPAIDRR---PSDALSGPRPDDLAYMTYTSGTTGV
TH_3730|M.thermoresistible__bu      GARLHRSGVPVIHIDDPAAPGQAG--ATTGPAPAPDDIAYIIYTSGTTGV
MAB_3317c|M.abscessus_ATCC_199      AHRLHGLGVPVLDVDDPAVCTQP---CTAPPMPSPEDLAHLIYTSGTTGV
Mflv_2697|M.gilvum_PYR-GCK          ARATAEPP-----------AQYRP--AETLPG----QAAYVVFTSGTTGE
MMAR_0099|M.marinum_M               AQRLAGYPVAVIDIDDPAIATCYP--GHGLPFPSADNIAYLIYTSGTTGK
Mb0104|M.bovis_AF2122/97            EGMTVASVLDEEQRTLNLAIWNRADLPACKTHPKVAERIAAALESMAAMW
Rv0101|M.tuberculosis_H37Rv         EGMTVASVLDEEQRTLNLAIWNRADLPACKTHPKVAERIAAALESMAAMW
MUL_1722|M.ulcerans_Agy99           -------------------------------------------MSPITRE
Mvan_2578|M.vanbaalenii_PYR-1       -------------------------------------------MSTDTRE
MLBr_00484|M.leprae_Br4923          -----------------------------MWRQQSISHRKESVMSTITKQ
                                                                                *  :  

MAV_3243|M.avium_104                PKGVAVTHRNVTEFLK----TLHPKLPSGPGQVWSQWHSLVFDV------
MSMEG_0402|M.smegmatis_MC2_155      PKAVAVTHHNVTQLVS----ALHADLPSGPGQVWSQWHSLVFDV------
TH_3730|M.thermoresistible__bu      PKGVAVTHRNVAALLS----ALDAELASG--QVWTQCHSLAFDF------
MAB_3317c|M.abscessus_ATCC_199      PKGVAVTQRNVVQLFD----RLDIGVELAPGQVWTQFHSYAFDF------
Mflv_2697|M.gilvum_PYR-GCK          PKGVIGTHRALLAYADDHIGAILRPAADRVGRPLRIAHAWSFTFD-----
MMAR_0099|M.marinum_M               PKGVGITHHNITQLFTSVAATGFTPAP---GQIWTQCHSYAFDY------
Mb0104|M.bovis_AF2122/97            DRPIAMIVNDWFGIGPDGTRCQGDWPARQPSTPAWFLDSARGVHQFLGRR
Rv0101|M.tuberculosis_H37Rv         DRPIAMIVNDWFGIGPDGTRCQGDWPARQPSTPAWFLDSARGVHQFLGRR
MUL_1722|M.ulcerans_Agy99           ER-LERRIQDLYANDPQ---------------------------------
Mvan_2578|M.vanbaalenii_PYR-1       DR-LARRIADLYATDPQ---------------------------------
MLBr_00484|M.leprae_Br4923          EKQLARRVDDLTANDPQ---------------------------------
                                     : :                                              

MAV_3243|M.avium_104                ---SVWETWGALLHGGRLVVVPESVAGSPDDLHDLLVAEGVTVLSQTPSA
MSMEG_0402|M.smegmatis_MC2_155      ---SVWEIWGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSA
TH_3730|M.thermoresistible__bu      ---SVWEIWGPLLYGGRVVIVPDPVVRSPEDLHALLAAEQVGMLSQTPSA
MAB_3317c|M.abscessus_ATCC_199      ---SVWEIWGALLHGGRLVVVPDSVARTPEDFHDLLMGERVTVMSQTPSA
Mflv_2697|M.gilvum_PYR-GCK          ---AAWQPLAALLDGHSVHIVDDATQRDAEALVDTIARFGVDMIDTTPSM
MMAR_0099|M.marinum_M               ---SVWEMWGALLHGGRLVVVPELVTRSAAELLALLVTEGVGVLSQTPSA
Mb0104|M.bovis_AF2122/97            RFVYPWVAWLVQRGAAPGDVLVFTDDDTDKTIDLLIACHLAGCGYSVCDT
Rv0101|M.tuberculosis_H37Rv         RFVYPWVAWLVQRGAAPGDVLVFTDDDTDKTIDLLIACHLAGCGYSVCDT
MUL_1722|M.ulcerans_Agy99           -----------FAAAKPVTAITAAIERPGLPLPQIIETVMTGY-------
Mvan_2578|M.vanbaalenii_PYR-1       -----------FAAAAPDDAISHAIDQPGTHLPVIVQTVLDGY-------
MLBr_00484|M.leprae_Br4923          -----------FAAAKPDPAVAAALAQPGLRLPQIIQTALDGY-------
                                                  .     :          :   :              

MAV_3243|M.avium_104                VGMLSPEG---------LDSTALVVAGEACPAEVVDRWAPGR-----VMI
MSMEG_0402|M.smegmatis_MC2_155      AGMLSPEG---------LESTTLIVAGEACPTELVDRWAPGR-----VMI
TH_3730|M.thermoresistible__bu      FYALQTADSLQPEQARQLQLQTVVFGGEALEPQRLSAWMRNHPER-PRLI
MAB_3317c|M.abscessus_ATCC_199      AGVLSPDG---------LEATALVIGAEPCPPELVDRWAPGR-----VMV
Mflv_2697|M.gilvum_PYR-GCK          FARLRDVGLLSTVP-----LAVLALGGEAVDPGLWQQIRQECARTGMSAF
MMAR_0099|M.marinum_M               FYALQAEDAAQPQLGRQLCLDAVVFGGEALEPARLGPWLANHGRR-PRLI
Mb0104|M.bovis_AF2122/97            ADEISVRTNAITEHGDGILVTVVDVAATQLAVVGHDELRKVVDER--VTQ
Rv0101|M.tuberculosis_H37Rv         ADEISVRTNAITEHGDGILVTVVDVAATQLAVVGHDELRKVVDER--VTQ
MUL_1722|M.ulcerans_Agy99           ------------------------------------ADRPALAQR--SVE
Mvan_2578|M.vanbaalenii_PYR-1       ------------------------------------AERPALGQR--AVR
MLBr_00484|M.leprae_Br4923          ------------------------------------AERPALGQR--VAE
                                                                                      

MAV_3243|M.avium_104                NAYGPTEATVYAAMSAP--LTAESGAPPIGSPVPGAALFVLDKWLRPAPE
MSMEG_0402|M.smegmatis_MC2_155      NAYGPTEATIYAAMSEP--LTAGTGVAPIGAPVPGAALFVLDKWLRPAPE
TH_3730|M.thermoresistible__bu      NMYGITETTVHASFREIGAADLDDNTSPIGRPLPHLAFFVLDGWLRPVPP
MAB_3317c|M.abscessus_ATCC_199      NVYGPTETTMWACKSAPLSAGSEGHGVPIGSPVAHAASFVLDRWLRPVPD
Mflv_2697|M.gilvum_PYR-GCK          NCYGPTETTVEAVVAEIGAHER----PTIGRPTAPTRAYVLDSWLRPVPS
MMAR_0099|M.marinum_M               NMYGITETTVHASFREIVRHDLGFAVSPVGVPLANLAFFVLDGWLRPVPV
Mb0104|M.bovis_AF2122/97            VTHDALLATKTAYIMPTSGTTGQPKLVRISHGSLAVFCDAISRAYGWGAH
Rv0101|M.tuberculosis_H37Rv         VTHDALLATKTAYIMPTSGTTGQPKLVRISHGSLAVFCDAISRAYGWGAH
MUL_1722|M.ulcerans_Agy99           FVTDAGTGHTTLRLLPH--------FETISYGELWDRISALADVLST---
Mvan_2578|M.vanbaalenii_PYR-1       FVTDPATGRTTTELLPR--------FETITYAELSRRIHAVTAALT----
MLBr_00484|M.leprae_Br4923          FTKDPKTGRTSMELLPS--------FETITYRQLGDRVGALARAWR----
                                       .                        :          .:         

MAV_3243|M.avium_104                GVVGELYIAGRGVATGYARRAGLTASRFVACPFGGPGARMYRTGDLVRWG
MSMEG_0402|M.smegmatis_MC2_155      GVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGERMYRTGDLVRWG
TH_3730|M.thermoresistible__bu      GVVGELYVAGAGLATGYVSRSDLTSTRFVACPFGPPGTRMYRTGDLVRWD
MAB_3317c|M.abscessus_ATCC_199      GVIGELYLAGAGVGSGYWRRTALTGARFVACPFGMPGDRMYRTGDLVSWG
Mflv_2697|M.gilvum_PYR-GCK          GAAGELYLAGGQLTRGYLGRPGETAARFVPDPF-VPGARMYRTGDVVRRA
MMAR_0099|M.marinum_M               GVAGELYVAGAGVGCGYWRRSGLTASRFVACPFGALGARMYRTGDVVRWG
Mb0104|M.bovis_AF2122/97            DTVLQCAPLTSDISVEEIFGGAACGARLVRSAAMKTGDLAALVDDLVARE
Rv0101|M.tuberculosis_H37Rv         DTVLQCAPLTSDISVEEIFGGAACGARLVRSAAMKTGDLAALVDDLVARE
MUL_1722|M.ulcerans_Agy99           --------------------------------------------------
Mvan_2578|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00484|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MAV_3243|M.avium_104                A----------------DGQLQYLGRADEQVKIRGYRIELGEIQSALAAL
MSMEG_0402|M.smegmatis_MC2_155      S----------------DGQLEYLGRADEQVKIRGYRIELGEIQAALAKL
TH_3730|M.thermoresistible__bu      T----------------GGELHYIGRADEQVKIRGYRIELGEIQAALARL
MAB_3317c|M.abscessus_ATCC_199      A----------------DGQLQYLGRADEQIKIRGYRIELGEIQAALVRL
Mflv_2697|M.gilvum_PYR-GCK          V----------------DGTLAFLGRSDTQVKIRGFRVEPGEVAAVLRTH
MMAR_0099|M.marinum_M               P----------------DGQLQYVGRADEQVKIRGYRIELGEVAAALSQL
Mb0104|M.bovis_AF2122/97            TTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVIGGEAIRCSAVDKWLES
Rv0101|M.tuberculosis_H37Rv         TTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVIGGEAIRCSAVDKWLES
MUL_1722|M.ulcerans_Agy99           ---------------------EQTVKPSDRVCLLGFNSVDYATIDMTLAR
Mvan_2578|M.vanbaalenii_PYR-1       -----------------------DVHPGDRVAVLGFTSIDYTTVDMALAM
MLBr_00484|M.leprae_Br4923          ---------------------HDLLHAGYRVCVLGFNSVDYAIIDMALGV
                                                             :.  :  : *               

MAV_3243|M.avium_104                DGVDQAAVIAREDRPGDKRLVGYITGTADPAELRTQLGKRLPAYMVPAAV
MSMEG_0402|M.smegmatis_MC2_155      DGVDQAVVIAREDRPGDKRLVGYITGTADPAQLRTALAESLPAYMVPTAV
TH_3730|M.thermoresistible__bu      DGVDQAAVIAREDRPGDKRLVGYITGTADPVQARAQLADRLPPYMVPAAI
MAB_3317c|M.abscessus_ATCC_199      DGVRQAAVIVREDRPGDKRIVGYITGGADPVGARAALAEQLPAYMVPVAV
Mflv_2697|M.gilvum_PYR-GCK          PAVGQAYVAVRPHRDG-HRLTAYVTGEPQLRELRAWLGRRLPRYLMPNAI
MMAR_0099|M.marinum_M               DGVDQAVVIAREDRPGDKRLVGYLVGSVDAGQARAALAQALPAYMVPAAV
Mb0104|M.bovis_AF2122/97            AASQGISLLSSYGPTEATVVATFLPIVCDQTTMDGALLRLGRPILPNTVF
Rv0101|M.tuberculosis_H37Rv         AASQGISLLSSYGPTEATVVATFLPIVCDQTTMDGALLRLGRPILPNTVF
MUL_1722|M.ulcerans_Agy99           LGAVAVPLQTSAAITQLQPIVAETQPTMIAASVD---------ALADATE
Mvan_2578|M.vanbaalenii_PYR-1       LGAVAVPLQTSAPATTVRPIVAETEPVVIASSVD---------ALTDAVG
MLBr_00484|M.leprae_Br4923          IGAVAVPLQTSAAITQLQSIVTETEPSMIATSVN---------QLPDTVE
                                     .     :           :.                       :   . 

MAV_3243|M.avium_104                VVLESLPLTVNGKLDKRALPAPEYHKRAGQYRAPSNHTEEILADIYAQVL
MSMEG_0402|M.smegmatis_MC2_155      VVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPAEQILADVYAQVL
TH_3730|M.thermoresistible__bu      VVLESIPLTSNNKLDVRALPAPEYRATGAEYRAPGTPLEGLLAGIFAEVL
MAB_3317c|M.abscessus_ATCC_199      VALQTLPVTVNGKLDKQGLPAPEY--SGVDFRAPSTPVEEALAGIYAQVL
Mflv_2697|M.gilvum_PYR-GCK          VAVDRIPLTAHGKIDEPALVALEP-AADGAATRPQTPTEVELAAVLAEVL
MMAR_0099|M.marinum_M               VVVDSLPLTVNGKLDIRALPAPQY-GATGSYRAPASPVEEVLAGIYAQVL
Mb0104|M.bovis_AF2122/97            LAFGEVVIVGDLVADGYLGIDGDGFGTVTAADGSRRRAFATGDRVTVDAE
Rv0101|M.tuberculosis_H37Rv         LAFGEVVIVGDLVADGYLGIDGDGFGTVTAADGSRRRAFATGDRVTVDAE
MUL_1722|M.ulcerans_Agy99           LALSGQTATRVLVFDHHRQVDAHRAAVESARER-----------------
Mvan_2578|M.vanbaalenii_PYR-1       LALDAPTVTRLVVFDHRAGVDDHRDALISASDR-----------------
MLBr_00484|M.leprae_Br4923          LILSGQAPAKLVVFDYHPEVDEQHDAVATARAR-----------------
                                    : .     .     *       .                           

MAV_3243|M.avium_104                GVERVGVDDSFFDLGGDSILSMQVVARARAAGVICRPRDVFVEQTVAR--
MSMEG_0402|M.smegmatis_MC2_155      GVERVGVDDSFFDLGGDSILSMQVVARARAAGIQCRPRDIFVEQTVAG--
TH_3730|M.thermoresistible__bu      GVERVGVDDSFFDLGGDSILSMQVVARARAAGVQCRPRDIFVEQTVAR--
MAB_3317c|M.abscessus_ATCC_199      GVDRVGADDSFFDLGGDSILAMQVAGRARAAGVLCRPRDIFVEQTVAR--
Mflv_2697|M.gilvum_PYR-GCK          GVGEIDVTADFLELGLDSIVALSVVQTARRRGVVMRAKLMLDCATVR---
MMAR_0099|M.marinum_M               GLDRVAVDQSFFDLGGDSILAIQVVARARAAGVVCRPRDVFTEQTVAGLA
Mb0104|M.bovis_AF2122/97            GFPVFSGRKDAVVKISGKRVDIAEVTRRIAEDPAVSDVAVELHSGSLGVW
Rv0101|M.tuberculosis_H37Rv         GFPVFSGRKDAVVKISGKRVDIAEVTRRIAEDPAVSDVAVELHSGSLGVW
MUL_1722|M.ulcerans_Agy99           ------------LAGS---AVVETLAEAIARGDVPRGASAGSAPGTD---
Mvan_2578|M.vanbaalenii_PYR-1       ------------LRAANSPIEVETITDIVARGSKLPVRAQFSADG-----
MLBr_00484|M.leprae_Br4923          ------------LADSS--VVVESLTEVLGRGKTLPATPIPVADDS----
                                                         :         .                  

MAV_3243|M.avium_104                -LARVASDGADEEQVVDEGIGPVQATPIMRWLQTVQGPIDDFNQTMVLAA
MSMEG_0402|M.smegmatis_MC2_155      -VARVAVAAG-ESHVVDEGVGPVVATPIMRWLREVDGPTGQFNQTVITQA
TH_3730|M.thermoresistible__bu      -LASVVKVSGGEPETVDDGTGAVVATPIMRWLRGVDGPTDQFNQTVVLQA
MAB_3317c|M.abscessus_ATCC_199      -LSRVVTLAENEIRNVDDGIGPVAPTPIMHWLHSVPGPVERFNQTVVLQA
Mflv_2697|M.gilvum_PYR-GCK          ELAAAIDDAGSGPPSADEGSGPIALLPNAHWLYEFGDP-RRLASTEALRL
MMAR_0099|M.marinum_M               TVAAVFDDANDDGGHAEDSVGEVVATPIMLWLQSLDGPLKEFNQTALLQA
Mb0104|M.bovis_AF2122/97            FKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVPNIPRKPNGKIDSD
Rv0101|M.tuberculosis_H37Rv         FKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVPNIPRKPNGKIDSD
MUL_1722|M.ulcerans_Agy99           --------------------------------------------------
Mvan_2578|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00484|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MAV_3243|M.avium_104                PSG------------------VTADDVAVVLQALLDRHPMLRLRVED---
MSMEG_0402|M.smegmatis_MC2_155      PAG------------------VTEDDVVVILQALLDRHATLRLRVEDT--
TH_3730|M.thermoresistible__bu      PPGT--------------DTAAAEADVVAVLQALIDRHPTLRMRAEGMTA
MAB_3317c|M.abscessus_ATCC_199      PAG------------------AAEADIVVLLQALLDHHGTLRLHAEN---
Mflv_2697|M.gilvum_PYR-GCK          PRG------------------ITGPQIRALLQSVVDAHPVLRTRLDR---
MMAR_0099|M.marinum_M               PAA------------------MSYGDVIVSLQAVLDRHAMLRLQVDT---
Mb0104|M.bovis_AF2122/97            NLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLGRAIGPDSSLLGEGIGS
Rv0101|M.tuberculosis_H37Rv         NLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLGRAIGPDSSLLGEGIGS
MUL_1722|M.ulcerans_Agy99           --------------------------------------------------
Mvan_2578|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00484|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MAV_3243|M.avium_104                -DGAGGWNLQAPEPGSVRAADCLQSVDTLSDAVLVAARSRLNPGAGVMVS
MSMEG_0402|M.smegmatis_MC2_155      QEDTDEWSLLVPEAGAVGARECLRTVDALTDDVLVEARNRLDPAAGAMVS
TH_3730|M.thermoresistible__bu      GDGTDDWSLFIPEPGATSAREVMHTVDTLTDEVLIAARSRLNPAAGVMLS
MAB_3317c|M.abscessus_ATCC_199      --NDGGWSLRVPEKGAVDARACIRTVEALSDEAVEAACSRLDPGAGAMLS
Mflv_2697|M.gilvum_PYR-GCK          -AAMTLVDGGFDLP--LTEIEVGDEGSAAVARHAAAALEHLDPQRGPLWG
MMAR_0099|M.marinum_M               -DATGRWLLHVPAPGCVDARKCVRAVTALSDDELVQARSRLDPSAGVMVS
Mb0104|M.bovis_AF2122/97            LDLIRILPETRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGEDRFRP
Rv0101|M.tuberculosis_H37Rv         LDLIRILPETRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGEDRFRP
MUL_1722|M.ulcerans_Agy99           -----------------------VSDDSLALLIYTSGSTGAPKG------
Mvan_2578|M.vanbaalenii_PYR-1       --------------------------DALSLLIYTSGSTGAPKG------
MLBr_00484|M.leprae_Br4923          -------------------------ADPLALLIYTSGSTGAPKG------
                                                               .                      

MAV_3243|M.avium_104                AVWAS-------ETSQLALIIHHVAVDGVSWRTLIEDLNIAWAQHHSGQP
MSMEG_0402|M.smegmatis_MC2_155      AVWVR-------ETSQLVLMIHHLAVDGVSWRILLEDLNIAWAQHCTGQS
TH_3730|M.thermoresistible__bu      AVWAR-------GSGQLVLMIHHLAVDGVSWRILVEDLNIAWAQHRTGQP
MAB_3317c|M.abscessus_ATCC_199      ALWAP-------AEGKLALVIHHLAVDGVSWRILLEDLNVAWAQRRSGLD
Mflv_2697|M.gilvum_PYR-GCK          AVWLRGSDDADSTSSVLLLTAHVLAMDPVSWQIVIGELDAGWHALAGGRA
MMAR_0099|M.marinum_M               ALWVT-------SSAQLALVIHHLAIDGVSWRILLDDLNSVWEQHRSGEM
Mb0104|M.bovis_AF2122/97            LVAAQ----RPAAIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDT
Rv0101|M.tuberculosis_H37Rv         LVAAQ----RPAAIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDT
MUL_1722|M.ulcerans_Agy99           AMYPR----RNVATFWR---KRTWFEGGYEPSITLNFMPMSHVMGRQILY
Mvan_2578|M.vanbaalenii_PYR-1       AMYPQ----HLVANSWRRLARSFWGDLGVFPAITLNFMPMSHVMGRGLLY
MLBr_00484|M.leprae_Br4923          AMYLQ----SNVGKMWRR-SDGNWFGP-TAASITLNFMPMSHVMGRGILY
                                     :                                :  :            

MAV_3243|M.avium_104                VALPAGGTSFARWSSLLAEHALTPAVVEQADAWREVVATPAVLPAVQPEV
MSMEG_0402|M.smegmatis_MC2_155      IELPAGGTSFARWSALLAEHAKTDTVRDLADAWRAVTSVPQALPPVQPDT
TH_3730|M.thermoresistible__bu      IDLPANGTSFARWSALLADHARAPEVVEHVEAWQRVIAAPSALPAIRPER
MAB_3317c|M.abscessus_ATCC_199      VALSGAGTSFARWASLLREQALSAGVVESADVWRSVSAVPPALPVVRPGV
Mflv_2697|M.gilvum_PYR-GCK          PAALGEHTGYRQWSNLLRERAESS--------------------------
MMAR_0099|M.marinum_M               AALPAGGTSFRRWAALLAEQAYSATAVDHAAAWRQVLATPSVLPAVKPAV
Mb0104|M.bovis_AF2122/97            EALGAAVADVVGRHESLRTVFPAVDGVPRQLVIEARRA------------
Rv0101|M.tuberculosis_H37Rv         EALGAAVADVVGRHESLRTVFPAVDGVPRQLVIEARRA------------
MUL_1722|M.ulcerans_Agy99           GTLCNGGTAYFVVKSDLSTLFEDLALVR----------------------
Mvan_2578|M.vanbaalenii_PYR-1       GTLDAGGTAYFAARSDLSTFLEDLALVR----------------------
MLBr_00484|M.leprae_Br4923          GTLGNGGTAYFAARSDLSTLLEDLKLVR----------------------
                                           :        *                                 

MAV_3243|M.avium_104                DTYQSAEQLSVSLDVDTTRLLLGEVPAAFHAGVQDILLIAFAMAWTQVVG
MSMEG_0402|M.smegmatis_MC2_155      DTYVTAGQLSASLDVETTRQLLGEVPAAFRAGVQDILLVAFGLAWTEFLN
TH_3730|M.thermoresistible__bu      DTYATAGQLSVSLDADTTRQLLGAVPAAFHAGVQDILLIAFGLAWAEFLG
MAB_3317c|M.abscessus_ATCC_199      DTYAVAGTLSVALDADVTRMLLGEVPAAFHAGVQDVLLIAFALAWNEFLG
Mflv_2697|M.gilvum_PYR-GCK          --------------------------------------------------
MMAR_0099|M.marinum_M               DTYATAQRLLVSLDIETTRTLLAAAPAAFHAGVQDILLIAFALAWSEFSS
Mb0104|M.bovis_AF2122/97            --------------------------------------------------
Rv0101|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_1722|M.ulcerans_Agy99           --------------------------------------------------
Mvan_2578|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00484|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MAV_3243|M.avium_104                -AGTPIGIDVEGHGRHEELGPHVDLSRTVGWFTTKYPVALAIDGLDWASV
MSMEG_0402|M.smegmatis_MC2_155      RSDTPIGVDVEGHGRYDELASDVDLSRTVGWFTTKYPVALTVENLPWEQV
TH_3730|M.thermoresistible__bu      ACDSPIGIDVEGHGRAEELAAGVDLSRTVGWFTTKYPVALTIPKLSWEQV
MAB_3317c|M.abscessus_ATCC_199      AGGAPIGIDLEGHGRAEELAADIDLSRTVGWFTAKYPAALSVGDLSWAQV
Mflv_2697|M.gilvum_PYR-GCK          --------------------------------------------------
MMAR_0099|M.marinum_M               GGGSRIAIDVEGHGRHEELAFGVDLSHTLGWFTTKYPVAVSVGALRWAQV
Mb0104|M.bovis_AF2122/97            ----------------------------------------DLGCDIVDAT
Rv0101|M.tuberculosis_H37Rv         ----------------------------------------DLGCDIVDAT
MUL_1722|M.ulcerans_Agy99           --------------------------------------------------
Mvan_2578|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00484|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MAV_3243|M.avium_104                VAGDDALGAAVKAAKEQLRALPDGLTYGLLRYLNPDVDLGGSDPVIGFNY
MSMEG_0402|M.smegmatis_MC2_155      VAGDAALGGIVKAVKEQLRSLPEGLTYGLLRYLNPEVDLGGSDPTIGFNY
TH_3730|M.thermoresistible__bu      RTGGDALGAAVKAAKEQLRSVPDGITYGLLRHLNPDVELGGAEPAIGFNY
MAB_3317c|M.abscessus_ATCC_199      SGGDSALGLVVKSVKEQLRGLPDPLSYGLLRYLNPEVALPHSDSAIGFNY
Mflv_2697|M.gilvum_PYR-GCK          ----------------------DGLQFWLD-------QLGGPDPALGARR
MMAR_0099|M.marinum_M               VAGDAALGAVVKDAKEQLRGLPDGLLYGLIRYLNREVELAGAEPTIGFNY
Mb0104|M.bovis_AF2122/97            AWPADRLQRAIEEAARHSFDLATEIPLRTWLFRIADDEHVLVAVAH----
Rv0101|M.tuberculosis_H37Rv         AWPADRLQRAIEEAARHSFDLATEIPLRTWLFRIADDEHVLVAVAH----
MUL_1722|M.ulcerans_Agy99           ---------------------PTELTFVPRVWDMVFDEFQSEVDRR----
Mvan_2578|M.vanbaalenii_PYR-1       ---------------------PTQLSFVPRIWDTIHAEVSQELERR----
MLBr_00484|M.leprae_Br4923          ---------------------PTELNFVPRIWETLYDESKRAVDRR----
                                                            :                         

MAV_3243|M.avium_104                LGRLGAAA-DLPGELWRLSPDSLSLSGAAAAVAMPLMHTVDLNAGTMDTE
MSMEG_0402|M.smegmatis_MC2_155      LGRLGAGAGELSEELWRIDQDSLALSDAASAVPMPLMHTVELNAGTIDTD
TH_3730|M.thermoresistible__bu      LGRLAAGAGDLPDELWRIDPSGLPITEAASKIPMPLAHTVEVNAGTLDAG
MAB_3317c|M.abscessus_ATCC_199      LGRLGAGATEASEDIWTISHEGLSWTSASSTVPMPMAHTVELNAGILESS
Mflv_2697|M.gilvum_PYR-GCK          VR------------------------------------------------
MMAR_0099|M.marinum_M               LGRL-STRTTAGDDHWQIARWGSLFTDECASAELPIQLFHTVELDAVTFD
Mb0104|M.bovis_AF2122/97            --------------------------------------------------
Rv0101|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_1722|M.ulcerans_Agy99           --------------------------------------------------
Mvan_2578|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00484|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MAV_3243|M.avium_104                --DGPHLHANWTWAPSAVDRDQISRLSQLWFEALAGICAHVRAGGGGLTP
MSMEG_0402|M.smegmatis_MC2_155      --NGPSLRASWTWAPSAFDEEQATRLSRLWFEALAGICAHVRGGGGGLTP
TH_3730|M.thermoresistible__bu      P-DGPVLQATWTWAPSLVDEAQIARLSRLWFEALGGVCAHVRSGGGGLTP
MAB_3317c|M.abscessus_ATCC_199      VESGPRLQAVWTWAPSLVDAIQVQRLSRLWFEALVGICTHVRTGGGGLTP
Mflv_2697|M.gilvum_PYR-GCK          --------------------------------------------------
MMAR_0099|M.marinum_M               TEAGPQLHAQWTWATSALDRAQLNRISRLWFEALTGICAHVRAGGGGMTP
Mb0104|M.bovis_AF2122/97            --------------------------------------------------
Rv0101|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_1722|M.ulcerans_Agy99           --------------------------------------------------
Mvan_2578|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00484|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MAV_3243|M.avium_104                SDILPARLNQRQIDELSKQHQIADILPLTPLQQGLLFHASFAQ-------
MSMEG_0402|M.smegmatis_MC2_155      SDVAPARLTQRQIDELSQRYDVTDVLPLTPVQQGLLFHSTFAR-------
TH_3730|M.thermoresistible__bu      SDIAPARLTQQQIDELADRHDIADILPLTPVQQGLLFHSAVTR-------
MAB_3317c|M.abscessus_ATCC_199      SDILPARLTQGELDELTKCLRVADVLPLTPVQQGLLFHSAIAARADSAAA
Mflv_2697|M.gilvum_PYR-GCK          --------------------------------------PDTDR-------
MMAR_0099|M.marinum_M               SDIGLTRLSQHQIDQLEQRYCVADVLPLTPLQQGLLFHADAAR-------
Mb0104|M.bovis_AF2122/97            --------------------------------------------------
Rv0101|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_1722|M.ulcerans_Agy99           --------------------------------------------------
Mvan_2578|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00484|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MAV_3243|M.avium_104                -DPGDDVYAVQLGITVTGALDSHRLHDAVHTVVNRHPNLAAR--FCPQYG
MSMEG_0402|M.smegmatis_MC2_155      -GIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAAR--FVEQFG
TH_3730|M.thermoresistible__bu      -TTADDIYAVQLDLTIAGVVDQHRLRDAVHAVVARHPNLAAR--FCTDHD
MAB_3317c|M.abscessus_ATCC_199      GTALADIYAVQLNLTMTGAVDPRRLYNAMHAVVKRHPNLVAR--FCTRFG
Mflv_2697|M.gilvum_PYR-GCK          --AGD----VRVTVTVTGADVTARLLAGPHPVLD----------------
MMAR_0099|M.marinum_M               --GGADLYVVQFDITLSGALDPRRLRTAAQEVLRRHPNLAAQFVWGEPLD
Mb0104|M.bovis_AF2122/97            --------HIAADGWSVAPLTADLSAAYASRCAGRAPDWAPL--------
Rv0101|M.tuberculosis_H37Rv         --------HIAADGWSVAPLTADLSAAYASRCAGRAPDWAPL--------
MUL_1722|M.ulcerans_Agy99           --------LVDG--ADRVALEAQVKAEIRNDVLG----------------
Mvan_2578|M.vanbaalenii_PYR-1       --------PSD---------ATEVIADLRRSLLG----------------
MLBr_00484|M.leprae_Br4923          --------LANSGSADRAAIKAEVMDEQRQSLLG----------------
                                                                                      

MAV_3243|M.avium_104                EPVQVVPADPVMAWRYIQLGPE---DVDPEQKVEELCAAERAAVSDLANR
MSMEG_0402|M.smegmatis_MC2_155      EPVQVLTADPMIAWRYLDLRGD---DLTPDHEIEQLCAAERSAVCDLLER
TH_3730|M.thermoresistible__bu      HPVQIIPTEPVAAWRYLDLRGD---DQNPEHEVQQLCAAERAAVRDLTER
MAB_3317c|M.abscessus_ATCC_199      EPVQVIPADPMICWQQTEFES--------TEELERFCAAERVAACDLAGK
Mflv_2697|M.gilvum_PYR-GCK          -----------------------------------------VLVAALG--
MMAR_0099|M.marinum_M               EPVQIILNDLVLEWRTVEFDPAGDPDAHVEQHIDEVCADERVAVADLGGG
Mb0104|M.bovis_AF2122/97            --------------------------------------------------
Rv0101|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_1722|M.ulcerans_Agy99           --------------------------------------------------
Mvan_2578|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00484|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MAV_3243|M.avium_104                PAFRAALIRTADNRHRFVLTNHHIVMDGWSLPILLREILAIYYGDQLPAP
MSMEG_0402|M.smegmatis_MC2_155      PTFRAALIRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYFGHRLPAA
TH_3730|M.thermoresistible__bu      PTFRAALIRTGATEHRFVLTVHHIVIDGWSLPILLQEIFAGYFGQRLPAP
MAB_3317c|M.abscessus_ATCC_199      STFRSALVRTGGDKHRFILTFHHVVIDGWSLPILLREIFAIYFGQALAPA
Mflv_2697|M.gilvum_PYR-GCK          --------------------------------------------------
MMAR_0099|M.marinum_M               SPFRIALIRTAPCEHRLVLTAHHIVCDGWSMPIVMQEILAAYAGQPLAAP
Mb0104|M.bovis_AF2122/97            -------------------------------------------------P
Rv0101|M.tuberculosis_H37Rv         -------------------------------------------------P
MUL_1722|M.ulcerans_Agy99           --------------------------------------------------
Mvan_2578|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00484|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MAV_3243|M.avium_104                ATYRSYLTWLAGQDRSAAQAAWRQVLDGFDTPTLVGPAGRMRLGRRAVES
MSMEG_0402|M.smegmatis_MC2_155      APYRNFVNWLATQDATAAKAAWREVLDGFETPTLVAPPG--VPGPRGIES
TH_3730|M.thermoresistible__bu      ARFRDFVTWLAAQDRDAARAAWRELLDGFDTPTLIAPPG--QAGPRGSAS
MAB_3317c|M.abscessus_ATCC_199      PSYRGFVSWLAQQDREAARAAWRKALEGFEAPTLVAPRS--VPGSRGVAS
Mflv_2697|M.gilvum_PYR-GCK          ---RTITEWRGRRNQPTP-------------PPLVALETHG---------
MMAR_0099|M.marinum_M               GSYRNFLTWLAERDKSAARTAWRELFADFRHPTLVGLPDHLGLGSRGVES
Mb0104|M.bovis_AF2122/97            VQYVDYTLWQREILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPY
Rv0101|M.tuberculosis_H37Rv         VQYVDYTLWQREILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPY
MUL_1722|M.ulcerans_Agy99           --------------------------------------------------
Mvan_2578|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00484|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MAV_3243|M.avium_104                YRLSADTTRALGELARACHTTVNTVLQAGWAQLLMRLTGQHDVAFGTAVS
MSMEG_0402|M.smegmatis_MC2_155      YRVSAETTRALGELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVS
TH_3730|M.thermoresistible__bu      YRIDTETTAAIGELARTQRTTVNTVLQAAWAHLLMAMTGQRDVVFGTAVS
MAB_3317c|M.abscessus_ATCC_199      YRISAETTRALGDLARSQHTTVSTVLRAAWAQLLMVQTGAHDVAFGTVVS
Mflv_2697|M.gilvum_PYR-GCK          -----------------------------------------RAALAEADT
MMAR_0099|M.marinum_M               YLLPIGITEALTELARSCRVTVNIVLQAAFAQLLSWLTGQHDVAFGTTVS
Mb0104|M.bovis_AF2122/97            PPVADQRGASLVVDWPASVQQQVRRIARQHNATSFMVVAAGLAVLLSKLS
Rv0101|M.tuberculosis_H37Rv         PPVADQRGASLVVDWPASVQQQVRRIARQHNATSFMVVAAGLAVLLSKLS
MUL_1722|M.ulcerans_Agy99           ------------------------------------------GRYTSALT
Mvan_2578|M.vanbaalenii_PYR-1       ------------------------------------------GRYVTAMT
MLBr_00484|M.leprae_Br4923          ------------------------------------------GRYIAAMT
                                                                                     :

MAV_3243|M.avium_104                G----------RPADLAGAESMVGLLINTVPVRANTHAETTVADLLDQLQ
MSMEG_0402|M.smegmatis_MC2_155      G----------RPADLAGAESMVGLLINTVPIRAKVSADTTVGDLLRQLQ
TH_3730|M.thermoresistible__bu      G----------RPADLPGADRIVGLLINTIPVRARIGADTTVADLLAQLQ
MAB_3317c|M.abscessus_ATCC_199      G----------RPALLTGADSVVGLLINTVPVRARATATTTVADLLRDMQ
Mflv_2697|M.gilvum_PYR-GCK          A----------DTADTADTSDTVGLLSAIYPLRLHEDSPGATTELIAGVP
MMAR_0099|M.marinum_M               G----------RPAEVAGVHSMVGLFINTVPTRARMASTTTTRELLDQLQ
Mb0104|M.bovis_AF2122/97            GSPDVAVGFPIAGRSDPALDNLVGFFVNTLVLRVNLAGDPSFAELLGQVR
Rv0101|M.tuberculosis_H37Rv         GSPDVAVGFPIAGRSDPALDNLVGFFVNTLVLRVNLAGDPSFAELLGQVR
MUL_1722|M.ulcerans_Agy99           G----------SAPISDEMKAWVEELLDMHLVEGYGSTEAGMILIDGAIR
Mvan_2578|M.vanbaalenii_PYR-1       G----------SAPLSPEMRAFVENLLDVHLIDGYGSTEAGAVFVDGRVQ
MLBr_00484|M.leprae_Br4923          G----------SAPTSPELKHGVESLLEMHLLEGYGSTEAGMVLFDGEVQ
                                    .                     *  :                  .   : 

MAV_3243|M.avium_104                Q---HHNDTLEHEHLALSEIHRVTGHDALFDTLFLYENYPIDTSVPLGFH
MSMEG_0402|M.smegmatis_MC2_155      S---HHNDTLEHEHLALNDIHHVSGHEQLFDTLFLYESYPIDTSAFMGVQ
TH_3730|M.thermoresistible__bu      H---AHNDTLEHEHLALTEIHHLAGHDQLFDTLFLYESYPIDTGAFSGAQ
MAB_3317c|M.abscessus_ATCC_199      S---IHNDLLEHEHLALNEIHHLAGHDRLFDTLFLYENYPVDVSTFMGTH
Mflv_2697|M.gilvum_PYR-GCK          AG-GIDYGLLRYLRPDTS--------------------------------
MMAR_0099|M.marinum_M               S---VHYETLEHHHLALSDIHRVSGHDQLFDTLFVYENYPIDKTAAQGTG
Mb0104|M.bovis_AF2122/97            ARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQDNPVGQLNLG
Rv0101|M.tuberculosis_H37Rv         ARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQDNPVGQLNLG
MUL_1722|M.ulcerans_Agy99           RPAVLDYKLVDVPDLGYFLTDRP------HPRGELLVKTDSLFPGYYQRA
Mvan_2578|M.vanbaalenii_PYR-1       RPPVIDYKLVDVADLGYFSTDRP------HPRGELLVKSETLFPGYYKRP
MLBr_00484|M.leprae_Br4923          RPPVIDYKLVDVPDLGYFSTDQP------YPRGELLLKTQNMFPGYYKRP
                                                                                      

MAV_3243|M.avium_104                ELAITDVTNREYNHYPLSVMALPGRE--------LGLRVEFDTDVFDAAG
MSMEG_0402|M.smegmatis_MC2_155      ELAVTEFNNREYNHYPLSVMALPGHE--------LGLRVEYDTSVFDVSE
TH_3730|M.thermoresistible__bu      ELAVTGFTNREFNHYPLSVMALPGHE--------LGLRIEYDTEVFDTAA
MAB_3317c|M.abscessus_ATCC_199      ELGITEFTSREYNHYPLSVMALPGHE--------LGIRIEYDTDAFDVAD
Mflv_2697|M.gilvum_PYR-GCK          ----------------EVLKAHPEPQ--------ILLNYLGRTDLVPSGA
MMAR_0099|M.marinum_M               ELAISGIGCREYSHYPLVVQAMPGDQ--------LGLRVEFRTDVFDAAS
Mb0104|M.bovis_AF2122/97            DLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQA
Rv0101|M.tuberculosis_H37Rv         DLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQA
MUL_1722|M.ulcerans_Agy99           EVTADVFDADGFYRTGDIMAEVGPEQ------------------------
Mvan_2578|M.vanbaalenii_PYR-1       DVTAEMFDEDGYYRTGDIVAETGADQ------------------------
MLBr_00484|M.leprae_Br4923          EVTATVFDSDGYYQTGDIVAEVGPDR------------------------
                                                      :                               

MAV_3243|M.avium_104                IEKLTERFQRVLSEMTADPTRRLTSLEVMDEAEHELLDAWGNRPVLSQPA
MSMEG_0402|M.smegmatis_MC2_155      IETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQLDEWANRAVLTQPV
TH_3730|M.thermoresistible__bu      IDALADRFRRVLESMVGDPARRLSAIEVLDAAEREQLDAWSNRAVLAD-S
MAB_3317c|M.abscessus_ATCC_199      IGALVQRLRRILGAMTAAPARRVLSIDVLEVAERGRLDSWGNRAVLACAT
Mflv_2697|M.gilvum_PYR-GCK          IVADRLLLS------------GLSTVPEPNAAVRHELTVV----------
MMAR_0099|M.marinum_M               IAALIQRLQRVVVAMVADPDRRLSSVDLLDAAEHARLDVVGNRAVLAEPL
Mb0104|M.bovis_AF2122/97            IDVLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPA
Rv0101|M.tuberculosis_H37Rv         IDVLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPA
MUL_1722|M.ulcerans_Agy99           --FVYLDRRNNVLKLSQGEFVTVSKLEAVFGDS-----------------
Mvan_2578|M.vanbaalenii_PYR-1       --LTYLDRRNNVLKLSQGEFVTVSRLEAVFGNS-----------------
MLBr_00484|M.leprae_Br4923          --LVYVDRRNNVLKLAQGQFVTVAKLEAAFSNS-----------------
                                                          :  :                        

MAV_3243|M.avium_104                TG-TSIPALFAAQVARTPDAAALTFQGRSMSYRELDEASNRLAHLLIEEG
MSMEG_0402|M.smegmatis_MC2_155      DSPQSIPEVFARQVERDPEAPAVTFEGESLNYGELDEAANQLANLLAVYG
TH_3730|M.thermoresistible__bu      PALESIPEVFARQVARDPGAVAVTFEGRSMTYGELDDAATELANLLAVYG
MAB_3317c|M.abscessus_ATCC_199      AASSSIPEVFARQVDRAPQAVALTFQGRSMTYRELDHAANRLAQLLASRG
Mflv_2697|M.gilvum_PYR-GCK          -----------AAVVAHGDEPALVAQWRVLPEILSDTDVEEMQTIWQDT-
MMAR_0099|M.marinum_M               VEPVSVPGLFAAQVASRAEVTALVCGDRSLTYRELDRAANRLAHLLVDQG
Mb0104|M.bovis_AF2122/97            PTPVSIPQMLAAQVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCG
Rv0101|M.tuberculosis_H37Rv         PTPVSIPQMLAAQVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCG
MUL_1722|M.ulcerans_Agy99           --PLVRQIYIYGNSARAYLLAVIVPTQEALDAVPVEELKARLGDSLQEVA
Mvan_2578|M.vanbaalenii_PYR-1       --PLVRQIYVYGNSARPYLLAVVVPTEAALAGA---DAKAAVAESLQDVA
MLBr_00484|M.leprae_Br4923          --PLVRQIYIYGNSAHPYLLAVVVPTEDALATNDIEVLKPLIIDSLQKVA
                                                         .:      :           :        

MAV_3243|M.avium_104                AGPGECVALLFSRSAEAIVSILAVLKTGAAYLPIDPALPAARIEFLLGDA
MSMEG_0402|M.smegmatis_MC2_155      AAPGKSVALMVPRSADAIVAILAVLKTGAAYLPIDPSVPAARLEFMLGDA
TH_3730|M.thermoresistible__bu      AGPGESVALLMPRSADAIVAILAVLKTGAAYLPIDPAVPAARLEFMLSDA
MAB_3317c|M.abscessus_ATCC_199      AGPGESIALMVPRSDDAIVALLAVLKTGAAYLPIDPAVPVARLEFMLADA
Mflv_2697|M.gilvum_PYR-GCK          --------------------LREVL-------------------------
MMAR_0099|M.marinum_M               VGPGDVVGLLLERSVEAVIAILAVLKSGAAYLAIDVNHPDGRIGFMIEDA
Mb0104|M.bovis_AF2122/97            AGPGECVALLFERCAPAVVAMVAVLKTGAAYLPIDPANPPPRVAFMLGDA
Rv0101|M.tuberculosis_H37Rv         AGPGECVALLFERCAPAVVAMVAVLKTGAAYLPIDPANPPPRVAFMLGDA
MUL_1722|M.ulcerans_Agy99           KAAG----------------------------------------------
Mvan_2578|M.vanbaalenii_PYR-1       KATG----------------------------------------------
MLBr_00484|M.leprae_Br4923          KEAD----------------------------------------------
                                                                                      

MAV_3243|M.avium_104                EPVAVVTTAALRSRLDGCKPSVVDVDDP---ALD-GQPSAALPVPSSDNI
MSMEG_0402|M.smegmatis_MC2_155      KPVAAVTTGDLRSRFDGFDLQVVEVDDP---AVE-IYPSTTLLTPSPDDI
TH_3730|M.thermoresistible__bu      EPIVALTTVELGTRFNGTGVPIIEVDDP---APP-MYPSSTLLPPAPDDI
MAB_3317c|M.abscessus_ATCC_199      APIAVATTAELRQRLAGSSIPVLVIDEH---VVD-EPAAVSLQAPRPDDI
Mflv_2697|M.gilvum_PYR-GCK          --------------------------------------------------
MMAR_0099|M.marinum_M               APVAVITTAGLAQRLAGYPVAVIDIDDP---AIATCYPGHGLPFPSADNI
Mb0104|M.bovis_AF2122/97            VPVAAVTTAGLRSRLAGHDLPIIDVVDALAA-----YPGTPPPMPAAVNL
Rv0101|M.tuberculosis_H37Rv         VPVAAVTTAGLRSRLAGHDLPIIDVVDALAA-----YPGTPPPMPAAVNL
MUL_1722|M.ulcerans_Agy99           --------------------------------------------------
Mvan_2578|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00484|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MAV_3243|M.avium_104                AYLIYTSGTTGVPKGVAVSHDNVAQLVES---LHAD-LPE--GGVWAQWH
MSMEG_0402|M.smegmatis_MC2_155      AYMIYTSGTTGVPKGVAITHGNVTQVLDT---LPAE-LPAGPGAVWSQWH
TH_3730|M.thermoresistible__bu      AYLIYTSGTTGVPKGVAITHANVTRVLHT---LPAD-LPAGPGKVWSQWH
MAB_3317c|M.abscessus_ATCC_199      AYTIYTSGTTGTPKGVAVTHRNVTQLLET---LPVG-LPAGPGQVWSQWH
Mflv_2697|M.gilvum_PYR-GCK          --------------------------------------------------
MMAR_0099|M.marinum_M               AYLIYTSGTTGKPKGVGITHHNITQLFTS---VAATGFTPAPGQIWTQCH
Mb0104|M.bovis_AF2122/97            AYILYTSGTTGEPKGVGITHRNVTRLFASLPAR------LSAAQVWSQCH
Rv0101|M.tuberculosis_H37Rv         AYILYTSGTTGEPKGVGITHRNVTRLFASLPAR------LSAAQVWSQCH
MUL_1722|M.ulcerans_Agy99           ------------------------------------------LQSYEIPR
Mvan_2578|M.vanbaalenii_PYR-1       ------------------------------------------LQSYEIPR
MLBr_00484|M.leprae_Br4923          ------------------------------------------LQSYEVPR
                                                                                      

MAV_3243|M.avium_104                SLVFDVSVHEIWGALLHGGRLVVVPESVAASPDELHDLLVAEGVTVLSQT
MSMEG_0402|M.smegmatis_MC2_155      SLVFDVSVWEIWGALLHGGRLVIVPESIAGSPDDLHALLVSEGVNVLYQT
TH_3730|M.thermoresistible__bu      SLVFDVSVWEIWGALLHGGRLVIVPESITGSPDDLHDLLVAEHVDVVYQT
MAB_3317c|M.abscessus_ATCC_199      SMVFDVSVWEVWGALLHGARLMVVPEAVAGSPQHLHDLLVTEKVSVLHQT
Mflv_2697|M.gilvum_PYR-GCK          --------------------------------------------------
MMAR_0099|M.marinum_M               SYAFDLSVFEMWGALLHGGRLVVVPESVTGSPADLHALLVAEQVDVLAQT
Mb0104|M.bovis_AF2122/97            SYGFDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQT
Rv0101|M.tuberculosis_H37Rv         SYGFDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQT
MUL_1722|M.ulcerans_Agy99           DFIIETTPWTLQNGLLTGIRKLARPQ------------------------
Mvan_2578|M.vanbaalenii_PYR-1       DFLLETTPFTLENGLLTGIRKLARPR------------------------
MLBr_00484|M.leprae_Br4923          DLIVETTPFSLENGLLTGIRKLAWPK------------------------
                                                                                      

MAV_3243|M.avium_104                PSAVGMLSPEGLDSTALVVAGEACPVEIVDRWAPGRVMINAYGPTEATVY
MSMEG_0402|M.smegmatis_MC2_155      PSAVRMMSPEGLEGTALVVAGEACPTEVVDRWAVDRVMINAYGPTESTIY
TH_3730|M.thermoresistible__bu      PSAAGMLSQRGLDSTALVVAGEACPTDLVDRWAPGRVMINAYGPTETTMC
MAB_3317c|M.abscessus_ATCC_199      PSAIGMLDWDGVDDMAVVVAGEPCPPEVVDRWAPGRLMLNAYGPTEATIY
Mflv_2697|M.gilvum_PYR-GCK          --------------------------------------------------
MMAR_0099|M.marinum_M               PSAVAMLSTQGLESTTLVVGGEACPAEVVDNWAPGRMMVNQYGPSETTMY
Mb0104|M.bovis_AF2122/97            PAAVAMLPTQGLESVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTIC
Rv0101|M.tuberculosis_H37Rv         PAAVAMLPTQGLESVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTIC
MUL_1722|M.ulcerans_Agy99           -------------------------------------LKKHYGELLEQIY
Mvan_2578|M.vanbaalenii_PYR-1       -------------------------------------LRERYGEQLEALY
MLBr_00484|M.leprae_Br4923          -------------------------------------LKQHYGARLEQLY
                                                                                      

MAV_3243|M.avium_104                AAMSTPLQPGTGSAPIGSPVPRAALFVLDRWLRPAPPGVVGELYIAGHGV
MSMEG_0402|M.smegmatis_MC2_155      AAISAPLSPGSDVVPIGSPVPKGATFVLDEWLRPVPPGVVGELYLAGRGV
TH_3730|M.thermoresistible__bu      VAISAPLTPGSGAVPIGTPVPRAALFVLDSWMRPVPAGVIGELYVAGDGV
MAB_3317c|M.abscessus_ATCC_199      AAISMPLSPKTSPVPIGSPVRGGATFVLDGWLRPVPPGVVGELYLAGSGV
Mflv_2697|M.gilvum_PYR-GCK          --------------------------------------------------
MMAR_0099|M.marinum_M               VSMSAPLVPGSGPAPIGVPVPRAALFVLDGWLRPVPAGVAGELYVAGAGV
Mb0104|M.bovis_AF2122/97            AAISAPLRPGSGMPPIGVPVSGAALFVLDSWLRPVPAGVAGELYIAGAGV
Rv0101|M.tuberculosis_H37Rv         AAISAPLRPGSGMPPIGVPVSGAALFVLDSWLRPVPAGVAGELYIAGAGV
MUL_1722|M.ulcerans_Agy99           TDLAH---------------------------------------------
Mvan_2578|M.vanbaalenii_PYR-1       TMLSE---------------------------------------------
MLBr_00484|M.leprae_Br4923          ADLVE---------------------------------------------
                                                                                      

MAV_3243|M.avium_104                ATGYARRSGLTASRFVACPFGGPGARMYRTGDLVRWNQDGQLEYLGRADE
MSMEG_0402|M.smegmatis_MC2_155      GVGYVGRSGLTGTRFVACPFGEPGARMYRTGDLVRWGDDGQLQYLGRADE
TH_3730|M.thermoresistible__bu      AVGYVGRSELTASRFVACPFGPPGSRMYRTGDLVRWGADGQLQYLGRADE
MAB_3317c|M.abscessus_ATCC_199      GVGYVHRSGLTGSRFVACPFGRPGVRMYRTGDLARYSEDGQLQYLGRTDE
Mflv_2697|M.gilvum_PYR-GCK          --------------------------------------------------
MMAR_0099|M.marinum_M               GCGYWRRSGLTASRFVACPFGALGARMYRTGDVVRWGPDGQLQYVGRADE
Mb0104|M.bovis_AF2122/97            GVGYWRRAGLTASRFVACPFGGSGARMYRTGDLVCWRADGQLEFLGRTDD
Rv0101|M.tuberculosis_H37Rv         GVGYWRRAGLTASRFVACPFGGSGARMYRTGDLVCWRADGQLEFLGRTDD
MUL_1722|M.ulcerans_Agy99           ---------------------------------------------GQADE
Mvan_2578|M.vanbaalenii_PYR-1       ---------------------------------------------EQADE
MLBr_00484|M.leprae_Br4923          ---------------------------------------------GQANA
                                                                                      

MAV_3243|M.avium_104                QVKLRGYRIELGEVQAALAGLDGVEQAAVIAREDRPGDKRLVGYITGTAD
MSMEG_0402|M.smegmatis_MC2_155      QVKIRGYRIELGEIQAALSDVDGVDQAVVIAREDRPGDKRLVGYITGTAD
TH_3730|M.thermoresistible__bu      QVKIRGYRIELGEVQTALTAVDGVENAVVIAREDRPGDKRLVGYITGTAD
MAB_3317c|M.abscessus_ATCC_199      QVKIRGYRIELDEIRSALAELDGVEHAAVIVREDRPGDKRLVGYVTGTAD
Mflv_2697|M.gilvum_PYR-GCK          --------------------------------------------------
MMAR_0099|M.marinum_M               QVKIRGYRIELGEVAAALSQLDGVDQAVVIAREDRPGDKRLVGYLVGSVD
Mb0104|M.bovis_AF2122/97            QVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVGYATEIAP
Rv0101|M.tuberculosis_H37Rv         QVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVGYATEIAP
MUL_1722|M.ulcerans_Agy99           LRSLR----------------QSGADAPVLVTVCRAAAALLGGSASDVQP
Mvan_2578|M.vanbaalenii_PYR-1       LRELR----------------RSGGERPALETVGRAAGALLGTTAGELEP
MLBr_00484|M.leprae_Br4923          LHVLK----------------QSVANAPVLQTVSRAVGTILGVATTDLPS
                                                                                      

MAV_3243|M.avium_104                ----PVGIRIQLAERLPAYMVPAAVVVLDALPLTVNGKLDKRALPAPEYR
MSMEG_0402|M.smegmatis_MC2_155      ----PAAARSELTNRLPAYMVPAAVVTLETLPLTVNGKLDRRALPAPEYQ
TH_3730|M.thermoresistible__bu      ----PDQARARLADRLPAYMVPTAVVVLDALPLTVNGKLDTRALPAPEYQ
MAB_3317c|M.abscessus_ATCC_199      ----PTMLRTLLGERLPQYMVPAAVVAVDAIPLTINGKLDKRSLPAPVYH
Mflv_2697|M.gilvum_PYR-GCK          --------------------------------------------------
MMAR_0099|M.marinum_M               ----AGQARAALAQALPAYMVPAAVVVVDSLPLTVNGKLDIRALPAPQYG
Mb0104|M.bovis_AF2122/97            GAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYG
Rv0101|M.tuberculosis_H37Rv         GAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYG
MUL_1722|M.ulcerans_Agy99           --------------------------------------------------
Mvan_2578|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00484|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MAV_3243|M.avium_104                KRGGEYIAPTNPTEETVAGIFARVLGMERVSIDDSFFELGGDSLSAMRVI
MSMEG_0402|M.smegmatis_MC2_155      S-AQRYRAPETETEKTLAGIFAHVLGVERIGLDDSFFDLGGDSISAMRVT
TH_3730|M.thermoresistible__bu      D-AEQYRAPTHAVEEVLAGIYAEVLGIDKVGVDDSFFDLGGDSISSMQVV
MAB_3317c|M.abscessus_ATCC_199      D-AARYREPVSPVERTIADIYAHTLGLERIGVEDSFFDVGGDSISAMRVV
Mflv_2697|M.gilvum_PYR-GCK          --------------------------------------------------
MMAR_0099|M.marinum_M               A-TGSYRAPASPVEEVLAGIYAQVLGLDRVAVDQSFFDLGGNSILAMRVS
Mb0104|M.bovis_AF2122/97            D-TNGYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVI
Rv0101|M.tuberculosis_H37Rv         D-TNGYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVI
MUL_1722|M.ulcerans_Agy99           --------------------------------DAHFTDLGGDSLSALSFT
Mvan_2578|M.vanbaalenii_PYR-1       --------------------------------SAHFTDLGGDSLSALTFA
MLBr_00484|M.leprae_Br4923          --------------------------------NAHFTDLGGDSLSALTFG
                                                                                      

MAV_3243|M.avium_104                AEINTAVDGALSVRTLFDSQSVRALS---QRITSGADAENAAGPGFAAVH
MSMEG_0402|M.smegmatis_MC2_155      AAVNTALDADLSVRTLFEAPTVAKLS---LHVEHDAG-ERTDRVSFAAVH
TH_3730|M.thermoresistible__bu      ARAR-AAGLTIRPRDIFVERTVARLAQ--VAVPTGADAAVDDAGTGPVVA
MAB_3317c|M.abscessus_ATCC_199      AAINTALDVDLEVWTIFDAPSVRSLSARLNGAVSASPIAESSRTSCASVH
Mflv_2697|M.gilvum_PYR-GCK          --------------------------------------------------
MMAR_0099|M.marinum_M               SAIEKFLGVDLPVRLMFEAPTVESLSR------------QVESPYSSVEL
Mb0104|M.bovis_AF2122/97            AAINTTLNADLPVRALLHASSTRGLSQLLGRDARP--TSDPRLVSVHGDN
Rv0101|M.tuberculosis_H37Rv         AAINTTLNADLPVRALLHASSTRGLSQLLGRDARP--TSDPRLVSVHGDN
MUL_1722|M.ulcerans_Agy99           NLLHEIFDIDVPVGVIVSPANDLQALADYVEAARKPGSSRPTFASVHGAS
Mvan_2578|M.vanbaalenii_PYR-1       NLLRDIFDVDVPVGVIVSPATDLQALADYVESARRHGSVRPTFESVHGHS
MLBr_00484|M.leprae_Br4923          SLLRELFDIDVPVGVIVSPVNNLVAIADYIERERQ-GTKRPTFIAIHGRD
                                                                                      

MAV_3243|M.avium_104                GADAKEVYARDLTLDKFLDATTLSTAPTLPGPSPEVRTVLLTGATGFLGR
MSMEG_0402|M.smegmatis_MC2_155      GSDVTEVHARDLTLDKFIDAPTLRTATTLPRPDGAVQTVLLTGATGFLGR
TH_3730|M.thermoresistible__bu      TPIMRWLYDTRGPIDQFNQTVVLR------APAGVTEADVVEILQAVLDR
MAB_3317c|M.abscessus_ATCC_199      GRGVTQVMATDLTLDKFVDVTALIANRSRRHPRGDVREILLTGATGFLGR
Mflv_2697|M.gilvum_PYR-GCK          --------------------------------------------------
MMAR_0099|M.marinum_M               APVELLKQGAGTPLFCLPPGGGLSWIYRNLGAYLDCPIIGIQQVPSDQEV
Mb0104|M.bovis_AF2122/97            PT---EVHASDLTLDRFIDADTLATAVNLPGPSPELRTVLLTGATGFLGR
Rv0101|M.tuberculosis_H37Rv         PT---EVHASDLTLDRFIDADTLATAVNLPGPSPELRTVLLTGATGFLGR
MUL_1722|M.ulcerans_Agy99           NEQVTEVHAGDLSLDKFIDAATLAEAPRLPAANTQVRTVLLTGATGFLGR
Mvan_2578|M.vanbaalenii_PYR-1       GRPGTEVHARDLTLDEFVDAATLAHAPTLPGPRAEVRTVLLTGATGFLGR
MLBr_00484|M.leprae_Br4923          AG---KVHASDLTLDKFIDVSTLTAAPVLAQPGTEVRTVLLTGATGFLGR
                                                                                      

MAV_3243|M.avium_104                YLVLEWLEQLEQVDGKLICLVRARSDEEAWGRLEKTFNTGDPELLRHFQE
MSMEG_0402|M.smegmatis_MC2_155      YLLLEWLRQLRRVDDKVICLVRGKSDEDARRRLEATFDT-DPLLRKHFNE
TH_3730|M.thermoresistible__bu      HAMLR----LRAADVENLTVPES-GAVTARGCLRTVHRLSGDELR-----
MAB_3317c|M.abscessus_ATCC_199      HLVLHWLREMEHAGGTLTCLVRGSSHEEARSRLEKSFDSGDPGLMALFRR
Mflv_2697|M.gilvum_PYR-GCK          --------------------------------------------------
MMAR_0099|M.marinum_M               EPGSVGDMARRYVDMIQAHHPDGPYNLLGWSMGGVVAHEIAVELRRRGCE
Mb0104|M.bovis_AF2122/97            YLVLELLRRLDVDG-RLICLVRAESDEDARRRLEKTFDSGDPELLRHFKE
Rv0101|M.tuberculosis_H37Rv         YLVLELLRRLDVDG-RLICLVRAESDEDARRRLEKTFDSGDPELLRHFKE
MUL_1722|M.ulcerans_Agy99           YLALEWLERMDLVDGKLICLVRAKSDTEARARLEKTFDSGAPELLAHYRA
Mvan_2578|M.vanbaalenii_PYR-1       YLALEWLERMALVGGKLICLVRAKDDAAARVRLDSTFDSGDPELLRHYRR
MLBr_00484|M.leprae_Br4923          YLALKWLERMDLVEGKVIALVRAKSNEDARARLDKTFDSGDPKLLAHYQE
                                                                                      

MAV_3243|M.avium_104                LAEEHLQVVAGDKGQANLGLDEQTWQQLADTVDLIVDSAAVVNGVLPYSE
MSMEG_0402|M.smegmatis_MC2_155      LATERLQVVAGDKGQPNLGLDEQTWQRLAESVDLIVDSAAFVNSVLPYSE
TH_3730|M.thermoresistible__bu      SARAELDPAAGTMVRALWAPDTRRLALIVH--HLAVDAVSWRILVEDINI
MAB_3317c|M.abscessus_ATCC_199      LAADRLKVVAGDKGEPHLGLEPQTWEHLAESVDLVVDSAAFVNSVLPYEE
Mflv_2697|M.gilvum_PYR-GCK          --------------------------------------------------
MMAR_0099|M.marinum_M               VGRLIVLDAAG-EVDSADSVAEPASESDVLELILVAAGIDIAEHPRPLTY
Mb0104|M.bovis_AF2122/97            LAADRLEVVAGDKSEPDLGLDQPMWRRLAETVDLIVDSAAMVN-AFPYHE
Rv0101|M.tuberculosis_H37Rv         LAADRLEVVAGDKSEPDLGLDQPMWRRLAETVDLIVDSAAMVN-AFPYHE
MUL_1722|M.ulcerans_Agy99           LAGDHLEVLAGDKGEADLGLDRQTWQRLADTVDLIVDPAALVNHVLPYSQ
Mvan_2578|M.vanbaalenii_PYR-1       LAADHLEVIAGDKADADLGLDARTWQRLADTVDLIVDPAALVNHVLPYRQ
MLBr_00484|M.leprae_Br4923          LATDHLEVIAGDKGEVDLELDRQTWRRLADTVDLIVDPAALVNHVLPYSE
                                                                                      

MAV_3243|M.avium_104                LFTPNVGGTAELIRLALTTRKKPFAYVSTSDVGRQIEPSAFTEDADIRVI
MSMEG_0402|M.smegmatis_MC2_155      LFGPNVVGTAELIRFALTSKLKPFNFVSTSDVGRQIEPSRFTEQADIRLV
TH_3730|M.thermoresistible__bu      AWGQRHTG----QPIDLPAGGTSFARWST----------LLAEYADTPEV
MAB_3317c|M.abscessus_ATCC_199      LFRPNVVGTAELIRLALTAKLKPYTFVSTSDVGRQVDRSKFTEVADIREI
Mflv_2697|M.gilvum_PYR-GCK          --------------------------------------------------
MMAR_0099|M.marinum_M               HEAEALLNQRTPVEFSLPPRRIVEIMLDNMNANQSMRLKHVPDVFDGDMI
Mb0104|M.bovis_AF2122/97            LFGPNVAGTAELIRIALTTKLKPFTYVSTADVGAAIEPSAFTEDADIRVI
Rv0101|M.tuberculosis_H37Rv         LFGPNVAGTAELIRIALTTKLKPFTYVSTADVGAAIEPSAFTEDADIRVI
MUL_1722|M.ulcerans_Agy99           LFGPNALGTAELLRLALTSKIKPYSYTSTIGVADQIPPSAFTEDADIRVI
Mvan_2578|M.vanbaalenii_PYR-1       LFAPNVLGTAELLRIALTTRMKPFVYVSTIGVGAGIEPARFTEDADIRQI
MLBr_00484|M.leprae_Br4923          LFGPNTLGTAELIRIALTSKQKPYIYVSTIGVGNQIEPAKFTEDSDIRVI
                                                                                      

MAV_3243|M.avium_104                SATRVIDGSYANGYGNSKWAGEVLLREAHDLCGLPVSVFRSDMILADTSY
MSMEG_0402|M.smegmatis_MC2_155      SATRKIEVGYANGYGNSKWAGEVLLREAHDHCGLPVAVFRSGMIMVDPTY
TH_3730|M.thermoresistible__bu      VAQAGVWQQVAAXX----WP----------SCSTPTTTSSSTSTWRSTRS
MAB_3317c|M.abscessus_ATCC_199      SPSRVLDAGYANGYANSKWAAEVLLREAHDMFGLPVAVFRSSMVMADTSY
Mflv_2697|M.gilvum_PYR-GCK          --------------------------------------------------
MMAR_0099|M.marinum_M               VFSAKRDSGGRSLADSWRQYVAGDITEYPIDCTHEAMLNIESLQLFADRI
Mb0104|M.bovis_AF2122/97            SPTRTVDGGWAGGYGTSKWAGEVLLREANDLCALPVAVFRCGMILADTSY
Rv0101|M.tuberculosis_H37Rv         SPTRTVDGGWAGGYGTSKWAGEVLLREANDLCALPVAVFRCGMILADTSY
MUL_1722|M.ulcerans_Agy99           SATRAVDDSYANGYSNSKWAGEVLLREAHVLCGLPVAVFRCDMILADTTW
Mvan_2578|M.vanbaalenii_PYR-1       SATRRIDDSYANGYGNSKWAGEVLLREAHDLCGLPVSVFRCDMILADTTY
MLBr_00484|M.leprae_Br4923          SPTRNINNNYANGYGNSKWAGEVLLREAHDLCGLPVTVFRCDMILADTSY
                                                                                      

MAV_3243|M.avium_104                AGQLNVTDIFTRMILSIVATGTAPKSFYRLDADGNRQRSHFDALPVEFVA
MSMEG_0402|M.smegmatis_MC2_155      AGQLNVTDTVSRMVLSIVATGVAPGSFYQRGDNGERQRAHFDGLPVDFVA
TH_3730|M.thermoresistible__bu      TGRP-------------VRTGCSTRCSSTRTIRSMRRR------------
MAB_3317c|M.abscessus_ATCC_199      AGQLNMADTISRMVLSIMATGVAPESFYQLDMHGNRQRAHFDGLPVEFVA
Mflv_2697|M.gilvum_PYR-GCK          --------------------------------------------------
MMAR_0099|M.marinum_M               AIYLR---------------------------------------------
Mb0104|M.bovis_AF2122/97            AGQLNMSDWVTRMVLSLMATGIAPRSFYEPDSEGNRQRAHFDGLPVTFVA
Rv0101|M.tuberculosis_H37Rv         AGQLNMSDWVTRMVLSLMATGIAPRSFYEPDSEGNRQRAHFDGLPVTFVA
MUL_1722|M.ulcerans_Agy99           AGQLNVPDMFTRMILSLAATGIAPGSFYELAADGARQRAHYDGLPVEFIA
Mvan_2578|M.vanbaalenii_PYR-1       AGQLNLPDMFTRLIFSLVATGVAPESFYHLATDGTRQRAHYDGLPVEFIA
MLBr_00484|M.leprae_Br4923          AGQLNVPDMFTRMMLSLAATGIAPGSFYELDAESNRQRAHYDGLPVEFIA
                                                                                      

MAV_3243|M.avium_104                EAIAKLGAQVMD--------GFETYHVMNPHDDGIGLDEYVDWLIEAGYP
MSMEG_0402|M.smegmatis_MC2_155      QAITKLGWQVARSVTDSTASGFETYHVMNPHDDGIGIDTYIDWLIEAGYP
TH_3730|M.thermoresistible__bu      ----WPGRKALR------------------------------------SP
MAB_3317c|M.abscessus_ATCC_199      EAIATLGSQATDG--------FETYHVMNPHDDGVGIDQFVDWLVEAGHP
Mflv_2697|M.gilvum_PYR-GCK          --------------------------------------------------
MMAR_0099|M.marinum_M               --------------------------------------------------
Mb0104|M.bovis_AF2122/97            EAIAVLGARVAG----SSLAGFATYHVMNPHDDGIGLDEYVDWLIEAGYP
Rv0101|M.tuberculosis_H37Rv         EAIAVLGARVAG----SSLAGFATYHVMNPHDDGIGLDEYVDWLIEAGYP
MUL_1722|M.ulcerans_Agy99           EAISTLGAQ--------SQDGFHTYHVMNPYDDGIGLDEFVDWLNESGCP
Mvan_2578|M.vanbaalenii_PYR-1       EAISTLGSD--------VASGFRTYHVMNPHDDGIGLDEYVDWLIDAGHP
MLBr_00484|M.leprae_Br4923          EAISTLGDQSL-----HDRDGFTTYHVMNPHDDGIGMDEFVDWLIDAGCP
                                                                                      

MAV_3243|M.avium_104                IERVDDFGEWLQRFETGLRGLPERQRQNSVLQMLLLLLRDPKNLQLAEPA
MSMEG_0402|M.smegmatis_MC2_155      IERIEDFGEWLQRFEAALQGLSDQQRQNSVLQMLTLLKQQAGELQPPVPT
TH_3730|M.thermoresistible__bu      ISRAANTTTIRCRWSQCPGTSSDCASN--------------------TTP
MAB_3317c|M.abscessus_ATCC_199      IERVGNFGVWLQRFEAGLRALPNPQRQNSVLQMLMVLKQHG-QLRAPAPT
Mflv_2697|M.gilvum_PYR-GCK          --------------------------------------------------
MMAR_0099|M.marinum_M               --------------------------------------------------
Mb0104|M.bovis_AF2122/97            IRRIDDFAEWLQRFEASLGALPDRQRRHSVLPMLLASNSQR--LQPLKPT
Rv0101|M.tuberculosis_H37Rv         IRRIDDFAEWLQRFEASLGALPDRQRRHSVLPMLLASNSQR--LQPLKPT
MUL_1722|M.ulcerans_Agy99           IQRIADYGDWLQRFETALRALPDRQRHSSLLPLLHNYR------QPERPV
Mvan_2578|M.vanbaalenii_PYR-1       IRRVGDYPTWLQRFTVAITALPERQRQASLLPLLHNYQ------HPETPI
MLBr_00484|M.leprae_Br4923          IQRINDYDEWLRRFEISLRALPERQRHSSLLPLLHNYQ------KPEKPL
                                                                                      

MAV_3243|M.avium_104                RGAFAPTDRFRAAVQEAKVGSDND---IPHISAPVIVKYVTDLQLLGLL
MSMEG_0402|M.smegmatis_MC2_155      RGSFAPADRFQAAVRDANIGVEGE---IPHVTREVIVKYVTDLQLLGLL
TH_3730|M.thermoresistible__bu      RCSTPRMSRHWSAGCGGC-------------------------------
MAB_3317c|M.abscessus_ATCC_199      CGSYAPADRFQAAVRRAKIGSDQD---IPHISAPIILKYVTDLQMLGLL
Mflv_2697|M.gilvum_PYR-GCK          -------------------------------------------------
MMAR_0099|M.marinum_M               -------------------------------------------------
Mb0104|M.bovis_AF2122/97            RGCSAPTDRFRAAVRAAKVGSDKDNPDIPHVSAPTIINYVTNLQLLGLL
Rv0101|M.tuberculosis_H37Rv         RGCSAPTDRFRAAVRAAKVGSDKDNPDIPHVSAPTIINYVTNLQLLGLL
MUL_1722|M.ulcerans_Agy99           RGSIAPTDRFRAAVQEAKIGPDKD---IPHVGAPIIVKYVSDLRLLGLL
Mvan_2578|M.vanbaalenii_PYR-1       RGSIAPTDRFREAVQDAKIGPDKD---IPHVTPQIVIKYVTDLQRLGLL
MLBr_00484|M.leprae_Br4923          HGSLAPTIRFRTAVQNANIGQDKD---IPHISPAIIAKYVSDLQLLGLV