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ARLDRAAVLAGAWAYIEAHGLDTLTMRKLAGSLGVNHGTLYWHVENKQALIDALANDLLTGVADDSHSSA AGMERLAELAHRLRAALLSHRDGARILAGTFVRESHTLTFGEAAIGAALDAGLTKQDAVLLAFSVQYYVT GFAIEEQAAHQRERTGDTPVRSDIDESRFPLVRAGLEILRNTARDKQFDYGLQRLLTT*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_1430c | - | - | 100% (199) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_2685 | - | 1e-22 | 37.18% (156) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_2380c | - | 2e-22 | 35.03% (197) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1388c | - | 7e-07 | 22.89% (201) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_3625 | - | 9e-20 | 34.97% (183) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1353c | - | 7e-07 | 22.89% (201) | transcriptional regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_4019 | - | 2e-05 | 22.77% (202) | transcriptional regulatory protein |
| M. avium 104 | MAV_5055 | - | 2e-05 | 35.06% (77) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_3193 | - | 1e-21 | 35.03% (197) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_0654 | - | 6e-22 | 37.36% (182) | transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_3884 | - | 2e-06 | 23.76% (202) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_2792 | - | 2e-20 | 37.34% (158) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3625|M.gilvum_PYR-GCK --------------------MQLSKRDVVDVATSLLDDYGIADLSMRRLA
Mvan_2792|M.vanbaalenii_PYR-1 --------------------MQLHKRDVVDVATSLLDDYGIADLSMRRLA
MSMEG_3193|M.smegmatis_MC2_155 --------------------MQLHKPDVVAAATKILDDHGIADLTMRRLA
TH_0654|M.thermoresistible__bu --------------------VQLRKSDVVDAATAILDNYGIADLTTRRLA
MAB_1430c|M.abscessus_ATCC_199 -------------------MARLDRAAVLAGAWAYIEAHGLDTLTMRKLA
Mb1388c|M.bovis_AF2122/97 -------MQTTPGKRQRRQRGSINPEDIISGAFELAQQVSIDNLSMPLLG
Rv1353c|M.tuberculosis_H37Rv -------MQTTPGKRQRRQRGSINPEDIISGAFELAQQVSIDNLSMPLLG
MMAR_4019|M.marinum_M MEVPVVAKRAAADKRQRRERGSINPDDIISGAFELAEQVSIDNLSMPMLG
MUL_3884|M.ulcerans_Agy99 MEVPVVAKRAAADKRQRRERGSINPDDIISGAFELAEQVSIDNLSMPMLG
MAV_5055|M.avium_104 -----------------MRRAGLKREAVVRAAVKIADAEGIEAISMRRVS
: :: * : .: :: :.
Mflv_3625|M.gilvum_PYR-GCK RELNVSAGALYWHFANKQQLLGAVADRILQPLTPA---SGN--WPERVRA
Mvan_2792|M.vanbaalenii_PYR-1 RELNVSPGALYWHFANKQQLLGAVADRILAAVDDV---PAG--WRDRIAG
MSMEG_3193|M.smegmatis_MC2_155 RELDVTPGALYWHFANKQELLGAVADHILRTARTD---TADLAWREQIHE
TH_0654|M.thermoresistible__bu RELGVTAGALYWHFANKQELLGAVADRILTPVPAG---EPEPGWAERISS
MAB_1430c|M.abscessus_ATCC_199 GSLGVNHGTLYWHVENKQALIDALANDLLTGVADDS--HSSAAGMERLAE
Mb1388c|M.bovis_AF2122/97 KHLGVGVTSIYWYFRKKDDLLNAMTDRALSKYVFATPYIEAGDWRETLRN
Rv1353c|M.tuberculosis_H37Rv KHLGVGVTSIYWYFRKKDDLLNAMTDRALSKYVFATPYIEAGDWRETLRN
MMAR_4019|M.marinum_M KHLGVGVTSIYWYFRKKDDLLNAMTDRALSKYVFATPYVEASDWRETLRN
MUL_3884|M.ulcerans_Agy99 KHLGVGVTSIYWYFRKKDDLLNAMTDRALSKYVFATPYVEGSDWRETLRN
MAV_5055|M.avium_104 QALGVTPMALYRYLPDKDALIDVVVDESLAVVPVP---DPSGSVTAELLR
*.* ::* :. .*: *:..:.: * :
Mflv_3625|M.gilvum_PYR-GCK TCAQLRDALLSH-----TDGAELVSASLAAGQSEVMTAVLARLAAAAGDA
Mvan_2792|M.vanbaalenii_PYR-1 ICAQLRDALLSH-----TDGAELVSASFAAGQSAAMTEVLGHLTAAAADA
MSMEG_3193|M.smegmatis_MC2_155 SCRALRDALLSH-----TDGAELVSASFASGQSVVITEIVEQLGRAARAA
TH_0654|M.thermoresistible__bu TAGRLRDALLSH-----TDGAELVSATFAAGQSRVLDEILARFAAAAAAA
MAB_1430c|M.abscessus_ATCC_199 LAHRLRAALLSH-----RDGARILAGTFVR-ESHTLTFGEAAIG-AALDA
Mb1388c|M.bovis_AF2122/97 HARSMRKTFADNP---VLCDLILIRAALSPKTARLGAQEMEKAIANLVTA
Rv1353c|M.tuberculosis_H37Rv HARSMRKTFADNP---VLCDLILIRAALSPKTARLGAQEMEKAIANLVTA
MMAR_4019|M.marinum_M HARLMRKTFMGNP---ILCDLILIRSALSPKAARLGAQEMERAIANLVEA
MUL_3884|M.ulcerans_Agy99 HARLMRKTFMSNP---ILCDLILIRSALSPKTARLGAQKMERAIANLVEA
MAV_5055|M.avium_104 CFGGLYDLLLDHPGLARAAGERPLEGPFATRLGNNVLTLLQHNKIDEADA
: : .: . : ..: . *
Mflv_3625|M.gilvum_PYR-GCK GVASEHTDLVARTVIYYVLG-FTADEQSRLQWDAAGAEVD-TTVWNEDPN
Mvan_2792|M.vanbaalenii_PYR-1 GVAPEHAELTARTVIYYVLG-FTADEQSRLQWDAAGADVA-QTVWAEDPS
MSMEG_3193|M.smegmatis_MC2_155 GVSDADVDAAARTVIYYVLG-FTVDEQSRLQWDAVGALGDDQSMLTRDGT
TH_0654|M.thermoresistible__bu GLEGSRAVLAARTIVHYVLG-FTGDEQSRLQWDAAGAEVA-EPPADDNPS
MAB_1430c|M.abscessus_ATCC_199 GLTKQDAVLLAFSVQYYVTG-FAIEEQAAHQRERTGDTPV-RSDIDESRF
Mb1388c|M.bovis_AF2122/97 GLSLEDAFDIYSAVSVHVRGSVVLDRLSRKSQSAGSGPSAIEHPVAIDPA
Rv1353c|M.tuberculosis_H37Rv GLSLEDAFDIYSAVSVHVRGSVVLDRLSRKSQSAGSGPSAIEHPVAIDPA
MMAR_4019|M.marinum_M GLSPEDAFDTYAAVSIHVRGSVVLHRLYEKTQSADSGPRAIEDAMNIDPL
MUL_3884|M.ulcerans_Agy99 GLSPEDAFDTYAAVSIHVRGSVVLHRLYEKTQSADSGPRAIEDAMNIDPL
MAV_5055|M.avium_104 ANLLVSAFSLTLGCALYRTSRSGRTASSRLSQVGDEAPAVRRLRGRLTVA
. . : .
Mflv_3625|M.gilvum_PYR-GCK --------------------ARFAFGLRLLTDGIAAHSRTGS--------
Mvan_2792|M.vanbaalenii_PYR-1 --------------------ARFTFGLHLLVDGIAVHSRAGT--------
MSMEG_3193|M.smegmatis_MC2_155 --------------------RQFRFGLQLLVDGLAAHGGGSEFTGFSSAE
TH_0654|M.thermoresistible__bu --------------------ARFAFGLNLLINGIAAEIDAAARKSE----
MAB_1430c|M.abscessus_ATCC_199 --------------------PLVRAGLEILRNTARDKQFDYGLQRLLTT-
Mb1388c|M.bovis_AF2122/97 TTPLLAHATGRGHRIGAPDETNFEYGLECILDHAGRLIEQSSKAAGEVAV
Rv1353c|M.tuberculosis_H37Rv TTPLLAHATGRGHRIGAPDETNFEYGLECILDHAGRLIEQSSKAAGEVAV
MMAR_4019|M.marinum_M TTPLLAQVSGKGHRIATPDEANFEYGLDCILDHAGRLIDERAKAA-KSAP
MUL_3884|M.ulcerans_Agy99 TTPLLAQVSGKGHRIATPDEANFEYGLDCILDHAGRLIDERAKAA-KSAP
MAV_5055|M.avium_104 S----------------ADDTVFRDALTRLIAGYVTTAAKTGGRRR----
. .* :
Mflv_3625|M.gilvum_PYR-GCK ---------------------
Mvan_2792|M.vanbaalenii_PYR-1 ---------------------
MSMEG_3193|M.smegmatis_MC2_155 RSFE-----------------
TH_0654|M.thermoresistible__bu ---------------------
MAB_1430c|M.abscessus_ATCC_199 ---------------------
Mb1388c|M.bovis_AF2122/97 RRPTATADAPTPGARAKAVAR
Rv1353c|M.tuberculosis_H37Rv RRPTATADAPTPGARAKAVAR
MMAR_4019|M.marinum_M SRPRKAAKPPAPRTRAKATTR
MUL_3884|M.ulcerans_Agy99 SRPRKAAKPPAPRTRAKATTR
MAV_5055|M.avium_104 ---------------------