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MQPMVDGRNKKGLLVTVAGVVQKYPALLVCAAALFAICAGLYGLPASQQLPAGGYDVPNSESMRAQQMLQ DKFGVGGNPIYFTVTSQGGATDTAALAAGRRVLDALNESPYIRQVTWWGAIPVGTANPLLSNDGKTGLVA ARLEGDDTDAPARARNLADPLIGDRNGVSIQGGGQALTYDAGNRQSREDLIVMEVIAFPVTFLALVWIFG SLVAALLPLAVSVFAIAGTTAALSALNLATNVSIFGVNVATALSLALAIDYTLFIVSRYREEQVAGATPA RALHVTMLTAGRTVLYSALTMACTVAVMLVFPQYLLKSLAYASLLSVLLSLIGALFLAPALLVILGDKLE RFDIRSVVGKLFKARKIGSPTASDRAWARIAAFSTNRPVVVVIIVGAILLLLGLPVLGIKIAYPDDRVLP VSQTARLAGDIVRTEFSQNFTADTRIVIRENASSRESVDDYAMKISHISGVQSVSAPGATFADGHRVGPG DAGRSGIEGASAYISLSTDTDPFSDPGKRQLETLKSVPAPGPVLVDSLAQRNLDNIGGITDRLPLVMAAI AVVTFVLIFLMTGSVILPIKALVMNLLSLCVAFGALVWIFQDGHLGGLGTVATGHFTAFIPPLLACIAYA LAIDYEIFVLSRIREAWLALPDNTPNRNKQAVAFGLIRTGRIVTAAATVMIVVFIAISAGQVAFMRGLGV GLAVGVAVDAFLVRPLLVPAFMQLMGRLNWWAPGPLARWHQRWGLVEEQEIPAEPAMTAAPEPDPVR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2275 | - | - | 100% (767) | MmpL family protein |
| M. abscessus ATCC 19977 | MAB_1287 | - | e-172 | 44.22% (735) | MmpL family membrane protein |
| M. abscessus ATCC 19977 | MAB_4508 | - | 3e-80 | 29.78% (779) | putative membrane protein, MmpL |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1177 | mmpL13 | 1e-170 | 43.47% (750) | transmembrane transport protein MmpL13 |
| M. gilvum PYR-GCK | Mflv_2131 | - | 1e-179 | 46.07% (738) | MMPL domain-containing protein |
| M. tuberculosis H37Rv | Rv1146 | mmpL13b | 5e-94 | 44.29% (429) | transmembrane transport protein MmpL13B |
| M. leprae Br4923 | MLBr_02620 | - | 5e-71 | 28.19% (791) | hypothetical protein MLBr_02620 |
| M. marinum M | MMAR_4810 | mmpL13_1 | 1e-172 | 44.44% (738) | transmembrane transport protein MmpL13_1 |
| M. avium 104 | MAV_1287 | - | 1e-175 | 43.62% (768) | mmpL protein |
| M. smegmatis MC2 155 | MSMEG_5178 | - | 0.0 | 45.78% (758) | integral membrane protein |
| M. thermoresistible (build 8) | TH_1538 | - | 1e-167 | 41.60% (762) | PROBABLE CONSERVED TRANSMEMBRANE TRANSPORT PROTEIN MMPL13B |
| M. ulcerans Agy99 | MUL_0989 | mmpL13 | 1e-172 | 42.30% (766) | transmembrane transport protein MmpL13 |
| M. vanbaalenii PYR-1 | Mvan_4573 | - | 1e-180 | 46.24% (744) | MMPL domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1177|M.bovis_AF2122/97 ------------MLQRIARLAIAAPRRIIGFAVFVFIAAAVFGVPVADSL
Rv1146|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1287|M.avium_104 ------------MLQKIARVAIAAPRRIIALGVLVFLAAAVFGIPVAKSL
MUL_0989|M.ulcerans_Agy99 ------------MLQGIARLAIAAPRRIIGVALLVFIAAAVFGIPVANSL
Mflv_2131|M.gilvum_PYR-GCK ------------MLHRIARLAIAAPRRVLMAALLVAIACGVFGIPVVTHL
Mvan_4573|M.vanbaalenii_PYR-1 ------------MLHRIALLAIAAPRRVLVVALLIMVGCGIFGAPVAKHL
MSMEG_5178|M.smegmatis_MC2_155 ------------MLQRIATTAIAAPRRILVVAALVMIAAGIFGIPVANKL
MMAR_4810|M.marinum_M ------------MLTRMARLSLSAPRRVIAVVVLVMIGTAIFGIPAANSL
TH_1538|M.thermoresistible__bu ------------MLETLARRIVAAPRRVLALVVLVIVGAAMFGLPVAGSL
MAB_2275|M.abscessus_ATCC_1997 MQPMVDGRNKKGLLVTVAGVVQKYPALLVCAAALFAICAGLYGLPASQQL
MLBr_02620|M.leprae_Br4923 ------------MFAWWGRTVYRYRFIVIGITVALCLCGGVFGLSLGKHV
Mb1177|M.bovis_AF2122/97 SPGGFQDPRSESARAIEVLTDKFGQSGQKMLIVVTAA---AGADSPPARE
Rv1146|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1287|M.avium_104 SPGGFQDPDSESARAIGVLTDKFGQSGQQMLILVTAP---GGSNSDPARR
MUL_0989|M.ulcerans_Agy99 SRGGFQDPNAESARAIKVLADKFGQSGQQMLILVTAP---GGVGTERARA
Mflv_2131|M.gilvum_PYR-GCK SAGGFQDPTSESARATQMLVDTFGQGDMELILAVTSD---DGAQSPAARD
Mvan_4573|M.vanbaalenii_PYR-1 SAGGFQDPTSESARATQLLVDKFDQGDMELLISITDDNSADGANSPAARA
MSMEG_5178|M.smegmatis_MC2_155 SAGGFQDPTAESARATQLLADKFHRGDMQLVIAVTAEAPGGRADGGRARE
MMAR_4810|M.marinum_M AAGGFLDPSSESARAAAVLADKFHRGDMEMVLLVSSD---DGVRDGPARI
TH_1538|M.thermoresistible__bu SAGGFRDPHSESAQASALLAERFDQTDMQLLVTVSSS---AGVYGEAARR
MAB_2275|M.abscessus_ATCC_1997 PAGGYDVPNSESMRAQQMLQDKFGVGGNPIYFTVTSQ---GGATDTAALA
MLBr_02620|M.leprae_Br4923 TQSGFYDDSSQSVKASILGDQVYGRDRSGHIVAIFHAPDGKTVNDPAWAK
Mb1177|M.bovis_AF2122/97 VGTDIVEVLRR--SPLVYNVTSPWTVP---PTAAADLLSTDGKSGLIVVN
Rv1146|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1287|M.avium_104 VGTELVEQLQR--SPLVYNVSSPWTAP---PQASADLVSRDGKSGLIVVN
MUL_0989|M.ulcerans_Agy99 VGTDIVAELNH--SPLVFNVSSPWTGPSADPKSAPDLVSKDGKSGLIVVN
Mflv_2131|M.gilvum_PYR-GCK VGVELVERLSD--SPHVAAITSAWTSP---PSAAPALISEDGRTGLIVAG
Mvan_4573|M.vanbaalenii_PYR-1 VGTDLADRLAA--SPHVGAVTSAWTAP---PSAAPALVSEDGRTGLIIAG
MSMEG_5178|M.smegmatis_MC2_155 VGTEIVSELKA--SPYVTEVTSAWTAP---PSAAAALVSKDARTGLIVAG
MMAR_4810|M.marinum_M VGTDIARQLAQ--SPFVAQVASPWDTP----QPPPDMLSADGKSALILVA
TH_1538|M.thermoresistible__bu VGTEIVAALEA--SPQVAGVQSPWTVP---PGAGDRLVSEDATAGLIVAP
MAB_2275|M.abscessus_ATCC_1997 AGRRVLDALNE--SPYIRQVTWWGAIP---VGTANPLLSNDGKTGLVAAR
MLBr_02620|M.leprae_Br4923 KITDELNQFQRNNSNKVTGWAGYLRASDTTNTVVQGMATPDKKYTFVSIP
Mb1177|M.bovis_AF2122/97 VKGGENDAQNHAQTLSDEVAHDRDGVTVRAGGSAMEYAQINRQNKDDLLV
Rv1146|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1287|M.avium_104 LKGGENFVQNNAQTLADQFVHDRDGVTVRAGGAAMQYAQINTQNQADLLV
MUL_0989|M.ulcerans_Agy99 IKGGESNAQKNAQTLADEIVHDRDGVTVRAGGSAMEYAQINKQNQDDLLV
Mflv_2131|M.gilvum_PYR-GCK ITGGESGAQKLAKALTDELVYDRDGVTVRAGGAAMTYVQINTQTEKDLLL
Mvan_4573|M.vanbaalenii_PYR-1 ITGGESEAQKHAKTLTDELVRDRDGVTVRAGGVAMTYVQINTQSEKDLLM
MSMEG_5178|M.smegmatis_MC2_155 LNGGENGAQQHAKELTDQFVRDHDGVRVRAGGEAMIYVQINGQSEKDLLM
MMAR_4810|M.marinum_M LKGDENSAPRHAQALAQRLAHDRGGVTVQAGGSAMVYAQVNQQTEKDLLR
TH_1538|M.thermoresistible__bu IRGNETESSDIARQLAAAVGSDRDRVNVRAGGPALVNAQIDTQTEHDLLV
MAB_2275|M.abscessus_ATCC_1997 LEGDDTDAPARARNLADPLIGDRNGVSIQGGGQALTYDAGNRQSREDLIV
MLBr_02620|M.leprae_Br4923 LKGDDDDTILNNYKAIAPDLQKLDGGTVQLAGLDPIANALTSTIATDQRR
Mb1177|M.bovis_AF2122/97 MELIAIPLSFLVLIWVFGGLLAAGLPMAQAVLAVVGSMAVLRLVTFATEV
Rv1146|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1287|M.avium_104 MEMIALPLSFLVLIWVFGGLLAAALPMALGALAVVGSMSVLRLITFTTEV
MUL_0989|M.ulcerans_Agy99 MELIAIPLSFLVLVWVFGGLLAAALPMALGALAVVGSMSVLRLVTFTTDV
Mflv_2131|M.gilvum_PYR-GCK MESIAIPLSFVVLVWVFGGLLAAALPLAVGVFAILGSMAVLRGFTLVTDV
Mvan_4573|M.vanbaalenii_PYR-1 MESIAIPLSFVVLVWVFGGLLAAALPLAVGAFAILGSMAVLRAVTLVTDV
MSMEG_5178|M.smegmatis_MC2_155 MESIAIPLSFVVLVWVFGGLLAAALPLAVGGFAILGSLAVLRLFTMVTDV
MMAR_4810|M.marinum_M MEFIAVPVSFAALVWVFGGLLAAALPVAVGGFAILGSLAVLRGVAMVTDV
TH_1538|M.thermoresistible__bu MEAIAIPLSFVVLVWVFGGLLAAALPLAVGVLAIVGSMAVLRTFTMFTEV
MAB_2275|M.abscessus_ATCC_1997 MEVIAFPVTFLALVWIFGSLVAALLPLAVSVFAIAGTTAALSALNLATNV
MLBr_02620|M.leprae_Br4923 MEVLALPLVAVVLFLVFGGVIAACLPVMVGGLSIAGALGILRFIALFGPV
Mb1177|M.bovis_AF2122/97 STFALNLSTALGLALAIDYTLLIVSRYRDELAEGSDRDEALIRTMATSGR
Rv1146|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1287|M.avium_104 SIFALNLSTALGLALAIDYTLLIVSRYRDELAEGHDRDQALIRTMATSGR
MUL_0989|M.ulcerans_Agy99 SIFALNLSTALGLALAIDYTLLIISRYRDELAEGSSREEALVRTMATSGR
Mflv_2131|M.gilvum_PYR-GCK SIFALNLSIAMGLALAIDYTLLIISRYRDELADGHDRDTALLRTMTTAGR
Mvan_4573|M.vanbaalenii_PYR-1 SIFALNLSIAMGLALAIDYTLLIISRYRDELAEGHDRDSALVRTMMTAGR
MSMEG_5178|M.smegmatis_MC2_155 SIFALNLTVAMGLALAIDYTLLIISRFRDELAEGADRETALVRTMMTAGR
MMAR_4810|M.marinum_M SIFALNVTVALGMALAIDYTLLIIRRYRDELGEGRSHEDALVRTMTTAGR
TH_1538|M.thermoresistible__bu SVFALNLSIAMGLALAIDYTLLLLNRYRDELAEGCSREQAVIRTMTSAGR
MAB_2275|M.abscessus_ATCC_1997 SIFGVNVATALSLALAIDYTLFIVSRYREEQVAGATPARALHVTMLTAGR
MLBr_02620|M.leprae_Br4923 HFFAQPVVSLIGLGIAVDYGLFVVSRFREEIAEGYDTEAAVRRTVMTAGR
Mb1177|M.bovis_AF2122/97 TVLFSAVTVALSMSATALFPMYFLKSFAYAGVATVAFVATASIVITPAAI
Rv1146|M.tuberculosis_H37Rv -------------------------------MATVAFVATASIVITPAAI
MAV_1287|M.avium_104 TVLFSAVTVALSMSATVAFPMYFLKSFAYAGVATVAFVATASIVITPAAI
MUL_0989|M.ulcerans_Agy99 TVLFSAVTVALSMSATVAFPMYFLKSFAYAGVATVAFVATASIVVTPAAI
Mflv_2131|M.gilvum_PYR-GCK TVVFSATTVALSMVAMVLFPMYFLKSFAYAGIAVVSFAALAAIVVTPAAI
Mvan_4573|M.vanbaalenii_PYR-1 TVLFSALTVALSMVAMVLFPMYFLKSFAYAGIAVVGFAAVAAIVVAPAAI
MSMEG_5178|M.smegmatis_MC2_155 TVLFSAMTVALSMVAMVLFPMYFLKSFAYAGIAVVALAATAAIVLTPAAI
MMAR_4810|M.marinum_M TVLFSAVTVGLSLVAMALFPMYFLKSFAYAGVAVVAFSALAAMVVAPTVI
TH_1538|M.thermoresistible__bu TVIFSAVIVATSMVPLALFPMYFLRSFAYAGVGVVAFALCAALVITPAAI
MAB_2275|M.abscessus_ATCC_1997 TVLYSALTMACTVAVMLVFPQYLLKSLAYASLLSVLLSLIGALFLAPALL
MLBr_02620|M.leprae_Br4923 TVTFSAVLIAASGASLLLLPQGFVKSLTYALIAAVTLAALLSITLLPACL
: * : :: : *: :
Mb1177|M.bovis_AF2122/97 VLLGPRLDALDVRRLVRRLLGRP-----------------DPVHKPVKQL
Rv1146|M.tuberculosis_H37Rv VLLGPRLDALDVRRLVRRLLGRP-----------------DPVHKPVKQL
MAV_1287|M.avium_104 VLLGDRLDALDVRRLLRRALRRA-----------------QPVRKPVEQL
MUL_0989|M.ulcerans_Agy99 VLLGPRLDALNVRRLARRMLGRP-----------------KPQHKPVDQL
Mflv_2131|M.gilvum_PYR-GCK ALAGDRLDALDVRRLVRRILGRP-----------------DPVAKPVEQN
Mvan_4573|M.vanbaalenii_PYR-1 VLAGARLDSMDVRRLVRRVLGRP-----------------EPVAKPVEQM
MSMEG_5178|M.smegmatis_MC2_155 VLLGDRLDAYDVRRFFRRVFGRP-----------------EPEPKPVEQG
MMAR_4810|M.marinum_M VLLGDRLDALNVWKLGRRLLGRP-----------------EPPPRPVAQS
TH_1538|M.thermoresistible__bu TVLGARLDSWDIRRLIRRLMRRTP-------------AAAEPAPRAVCGS
MAB_2275|M.abscessus_ATCC_1997 VILGDKLERFDIRSVVGKLFKAR-----------------KIGSPTASDR
MLBr_02620|M.leprae_Br4923 AILAKHVDALGVRTLFRVPLLRNWRMSHACLNWLADRLQKTKTREEVEAG
.: . ::: .: . : .
Mb1177|M.bovis_AF2122/97 FWYRSSKFVMRRWLPVGTAVVALLVLLGLPFLSVKWGFPDDRVLPRSASA
Rv1146|M.tuberculosis_H37Rv FWYRSSKFVMRRWLPVGTAVVALLVLLGLPFLSVKWGFPDDRVLPRSASA
MAV_1287|M.avium_104 FWYRSSKFVMRRWAPVGLIVVGLLLLLGLPFFSVKWGFPDDRVLPRSASA
MUL_0989|M.ulcerans_Agy99 FWYRSTKFVMRRALPVGLAVVAVLVILGLPFFSVKWGFPDDRVLPATASS
Mflv_2131|M.gilvum_PYR-GCK FWYRSTTFVMRRSIPIGGVVVVLLVLLGAPFLGATWGFPDDRVLPETASA
Mvan_4573|M.vanbaalenii_PYR-1 FWYRSTKFVMRRSIPIGVVVVTLLLLLGAPFLGANWGFPDDRVLPQSASA
MSMEG_5178|M.smegmatis_MC2_155 FWYRTAKAAMRRAVPIGVGIIALLVLLGVPFTGIKWGFPDDRVLPQSASA
MMAR_4810|M.marinum_M FWYRTAKLVTRHAIPVGLAIIVLLIALGIPFLNIKWGYPDDRVLPPSASA
TH_1538|M.thermoresistible__bu KWYRWAKAVMRHWLVAGLAVTVVLLLLGAPFLGVRWGFPDERVLPRSASA
MAB_2275|M.abscessus_ATCC_1997 AWARIAAFSTNRPVVVVIIVGAILLLLGLPVLGIKIAYPDDRVLPVSQTA
MLBr_02620|M.leprae_Br4923 FWGKLVNFVMKRPLVFAIPIVIGMILLVIPLGNLSFGGMSEKYLPPNNAV
* : .: : :: * *. . . .:: ** . :
Mb1177|M.bovis_AF2122/97 RQVGDILRDDFGHDPATQIPIVVPDARGLGPVELDSYAAELSRVPDVSAV
Rv1146|M.tuberculosis_H37Rv RQVGDILRDDFGHDPATQIPIVVPDARGLGPVELDSYAAELSRVPDVSAV
MAV_1287|M.avium_104 HQVGDRLRSGFAHDSATSVPVVIPDAAGLSPADLDDYAAALSRVPDVSAV
MUL_0989|M.ulcerans_Agy99 HQVGDELRTNFAHDLAMAVPVVVPDVHGLVPADLDGYAADLSRVPDVASV
Mflv_2131|M.gilvum_PYR-GCK RQIGDELRQDFAVDSSTNVVVVLPDADGISREDFDAYAIALSGVADVSSV
Mvan_4573|M.vanbaalenii_PYR-1 RQVGDELRTDFAVDSSANVVVVLPDAEGLGPDALDGYAAELSRVQDVSSV
MSMEG_5178|M.smegmatis_MC2_155 RQIGDEMRTNFAVDSATSVTVVLPDATTVAPAEIDRYAARLSQVADVSSV
MMAR_4810|M.marinum_M RMVSDRIRSDFGSNSASRVTVVITDTAGLTKPDLNHYAAQLSEVSDVSAV
TH_1538|M.thermoresistible__bu HQVGHELRTNFATDSASDVTVVLPDAPGLTADELAGYAARLSEVTDVAWV
MAB_2275|M.abscessus_ATCC_1997 RLAGDIVRTEFSQNFTADTRIVIRENASS-RESVDDYAMKISHISGVQSV
MLBr_02620|M.leprae_Br4923 RQSQEHFDQLFPG-YRTNPLTLVIQTSNHQPVTDQEIADIRSKAMAISGF
: . . * :: : * * : .
Mb1177|M.bovis_AF2122/97 AAPTGTFVDGSWVGT-PRGATGLAEGSAFLTVSSTAPLFSRASDIQLKRL
Rv1146|M.tuberculosis_H37Rv AAPTGTFVDGSWVGT-PRGATGLAEGSAFLTVSSTAPLFSRASDIQLKRL
MAV_1287|M.avium_104 SAPGGTFTGGTRVGP-PAGATGLGDGSAFLTVSSTAPLFSTANDVQLKRL
MUL_0989|M.ulcerans_Agy99 TAPSGTFVNGSRVGP-PAGATGFSDGSAFLTVDSTAPLFSHASDIQLKRL
Mflv_2131|M.gilvum_PYR-GCK SAPSGTFIGGARAGP-PSAATGSADGSAFLTIGSRAPLFTDASEVQLDRL
Mvan_4573|M.vanbaalenii_PYR-1 SAPGGTFVDGAKAGP-PSAATGIAEGSAFLTIGSTAPLFTDASETQLDRL
MSMEG_5178|M.smegmatis_MC2_155 SAPGGTDVQGRHVGP-PSAATGIGDGSAFLTVGSDAPLFSDASEAQLDAL
MMAR_4810|M.marinum_M SAPTGTFVAGELRGP-PSAPTAMAAGSAYLTVESTAPLYTKASANQLDRL
TH_1538|M.thermoresistible__bu SAPAGTFVRGRSVGP-PSAPTGIADGSAFVTVGSVAPLFSDDSLEQLNDI
MAB_2275|M.abscessus_ATCC_1997 SAPGATFADGHRVGPGDAGRSGIEGASAYISLSTDTDPFSDPGKRQLETL
MLBr_02620|M.leprae_Br4923 IEPDNNYVNMWQERTVAPGAS----KDPSVRVLQNGLINPNDASKKINEL
* . . . : .. : : . ::. :
Mb1177|M.bovis_AF2122/97 HQVAGPAGRSVVMAGVAQVNRDSVDAVTDRLPMVLGLIAAITYVLLFLLT
Rv1146|M.tuberculosis_H37Rv HQVAGPAGRSVVMAGVAQVNRDSVDAVTDRLPMVLGLIAAITYVLLFLLT
MAV_1287|M.avium_104 HEVPGPAGRSVEMGGVAQVNRDSVDAVTDRLPLVLGLMAAITFVLLFLLT
MUL_0989|M.ulcerans_Agy99 HQVTGPAGRTVEMAGVAQVNRDSVDAVTERLPLVLGLMAAITFVLLFLLT
Mflv_2131|M.gilvum_PYR-GCK HAIAPPGDRQVLLTGLAQINRDSADAITSRLPLVLAVIAAITFVLLFVLT
Mvan_4573|M.vanbaalenii_PYR-1 HDVAPPEGRDVLLTGLAQINRDSADAITSRLPTVLAVIAAITFVLLFLLT
MSMEG_5178|M.smegmatis_MC2_155 HAVAAH--AEVQFTGVAQVNRDSSQAITSRLPLVLGIIAGITFVLLFLLT
MMAR_4810|M.marinum_M HAVALPGDTAVQMTGVAQMNRDSVNGITSRLPMVFGFIAIVTLVLLFLLT
TH_1538|M.thermoresistible__bu RAVPAPGGTAVQLTGTAQINHDIVVAVTSRLTVVLTVIALTTLVWLFLLT
MAB_2275|M.abscessus_ATCC_1997 KSVPAPG--PVLVDSLAQRNLDNIGGITDRLPLVMAAIAVVTFVLIFLMT
MLBr_02620|M.leprae_Br4923 RSITPPKGLTVSVGGTPALEQDSIHSLVAQAPLMVIMLITTTMLLMFLAF
: :. * . . . : * .:. : . :. : * : :*:
Mb1177|M.bovis_AF2122/97 GSVVLPAKALVCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMPV
Rv1146|M.tuberculosis_H37Rv GSVVLPAKALVCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMPV
MAV_1287|M.avium_104 GSVLLPAKALACNFLSLTAAFGALVWIFQDGHLGALGTTPSGTLVANMPV
MUL_0989|M.ulcerans_Agy99 GSVVLPAKALICNVLSLTAAFGALVWIFQDGHLGALGTIPSGTLVANMPV
Mflv_2131|M.gilvum_PYR-GCK GSVVLPLKALVLNVLSLTAAFGALVWIFQEGHLGALGTTPTGTLVATMPV
Mvan_4573|M.vanbaalenii_PYR-1 GSVVLPLKALVLNVLSLTAAFGALVWIFQDGHLGALGTTPTGTLVANMPV
MSMEG_5178|M.smegmatis_MC2_155 GSVVLPLKALVLNVLSLSAAFGALVWIFQDGHLGALGTTPTGTLVANLPV
MMAR_4810|M.marinum_M GSVLLPIKAVVLNMLSLTAAFGALVWIFQDGHLGALGTTPTGTLVANIPV
TH_1538|M.thermoresistible__bu GSIVLPIKALVLNALSLTAAFGALVWIFQDGHLGALGTTPSGTMAVTMPA
MAB_2275|M.abscessus_ATCC_1997 GSVILPIKALVMNLLSLCVAFGALVWIFQDGHLGGLGTVATGHFTAFIPP
MLBr_02620|M.leprae_Br4923 GSFVLPIKAAVMSALTLGSTMGILTWIFVDGHLSKWLNFTPTPLMVVIIA
**.:** ** . *:* ::* *.*** :**:. . .. : . :
Mb1177|M.bovis_AF2122/97 LLFCIAFGLSMDYEVFLVSRIREYWLESGAAR------PARRSVAEVHAA
Rv1146|M.tuberculosis_H37Rv LLFCIAFGLSMDYEVFLVSRIREYWLESGAAR------PARRSVAEVHAA
MAV_1287|M.avium_104 LLFCIAFGLSMDYEVFLLSRIREYWLASGAAR------PARPTPKRAHAA
MUL_0989|M.ulcerans_Agy99 LLFCIAFGLSMDYEVFLVARIREYWLASGAAG------PATPSPAQAHAA
Mflv_2131|M.gilvum_PYR-GCK LLFCIAFGLSMDYEVFLVSRIREYWLETG--------------------E
Mvan_4573|M.vanbaalenii_PYR-1 LLFCIAFGLSMDYEVFLVSRIREYWLASGGAGADSSTAHQRSDDLAPHVR
MSMEG_5178|M.smegmatis_MC2_155 LLFCIAFGLSMDYEVFLVSRIREFWLQSDQS----------------RAA
MMAR_4810|M.marinum_M LMFCIAFGLSMDYEVFLLSRIREFWLGSPQQS----------------AD
TH_1538|M.thermoresistible__bu LLLCVAFGISMDYEVFLIARIREHWLASSRTA----------------AA
MAB_2275|M.abscessus_ATCC_1997 LLACIAYALAIDYEIFVLSRIREAWLALPDNTP---------------NR
MLBr_02620|M.leprae_Br4923 LVVAVGYGLATDYEVFLVSRMVEARAESMSTQ------------------
*: .:.:.:: ***:*:::*: *
Mb1177|M.bovis_AF2122/97 NDESVALGVARTGRVITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVA
Rv1146|M.tuberculosis_H37Rv NDESVALGVARTGRVITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVA
MAV_1287|M.avium_104 NDESVALGVARTGRVITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVF
MUL_0989|M.ulcerans_Agy99 NDESVALGLARTGRVITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAMA
Mflv_2131|M.gilvum_PYR-GCK NGRSVALGLARTGRVVTAAALVMSISFAALIAAQVSFMRMFGGGLTLAVL
Mvan_4573|M.vanbaalenii_PYR-1 SDESVALGLARTGRVVTAAALLMSISFAALIAAKVAFMRMFGVGLTLAIL
MSMEG_5178|M.smegmatis_MC2_155 NEESVALGLAHTGRVITAAALLMSISFAALIAAQVAFMRMFGLGLTLAVL
MMAR_4810|M.marinum_M NDESIALGLAHTGRVITAAALLMSISFAGLISAEVSFMRMFGVGLTIAVL
TH_1538|M.thermoresistible__bu NDEAVALGVARTARVITAAALIMSISFAALIGAQVSFMRMIGLGLMVAVL
MAB_2275|M.abscessus_ATCC_1997 NKQAVAFGLIRTGRIVTAAATVMIVVFIAISAGQVAFMRGLGVGLAVGVA
MLBr_02620|M.leprae_Br4923 --EAVRIGTASTGRLITAAALVLAVVAGSFVFSDLVMMKYLAFGLMAALL
.:: :* *.*::**** :: : .: ..: :*: :. ** .:
Mb1177|M.bovis_AF2122/97 ADATLVRMVVVPAFMHVTGRWNWWAPRPLAWLHERFGVSEAAEPVSRRRS
Rv1146|M.tuberculosis_H37Rv ADATLVRMVVVPAFMHVTGRWNWWAPRPLAWLHERFGVSEAAEPVSRRRS
MAV_1287|M.avium_104 ADATLVRMVVVPAFMHVMGRWNWWAPKPLAWLHDRFGISEAADEEPRLRA
MUL_0989|M.ulcerans_Agy99 ADATLVRMVLVPAFMHVMGRWNWWAPKPLVWLHQRFGISETGAVGGADAA
Mflv_2131|M.gilvum_PYR-GCK VDATLVRMLLVPAFMHLLGRWNWWAPPPLARLHARIGVSETVP-------
Mvan_4573|M.vanbaalenii_PYR-1 ADATLVRMLLVPAFMHVLGRWNWWAPKPLARLHERIGFSETLDDSSDSPP
MSMEG_5178|M.smegmatis_MC2_155 VDATLVRMLLVPAFMRVMGRWNWWAPAPLARLHERIGFSESGLPPDPKP-
MMAR_4810|M.marinum_M VDATLVRVLLVPAFMHVFGGLNWWAPKPLERWHSRSGADRSAGQTGPSDG
TH_1538|M.thermoresistible__bu VDATLVRLILVPAFMHVMGRANWWAPAPLARWHDRFGIREAADAPDRPRS
MAB_2275|M.abscessus_ATCC_1997 VDAFLVRPLLVPAFMQLMGRLNWWAPGPLARWHQRWGLVEEQEIPAEPAM
MLBr_02620|M.leprae_Br4923 LDATVVRMFLVPSVMKLLGDDCWWAPRWARLLQNRIGLGEIHLPDERRRP
** :** .:**:.*:: * **** : * * .
Mb1177|M.bovis_AF2122/97 HAGG--LGKIAGRSDGQT---------IPAS-----------LTRNG---
Rv1146|M.tuberculosis_H37Rv HAGG--LGKIAGRSDGQT---------IPAS-----------LTRNG---
MAV_1287|M.avium_104 CPRTRRIRRIARRRGRRTGAQHRLTAVRPTARRVWRSDPILRLIRGGRCT
MUL_0989|M.ulcerans_Agy99 ATEA------ADRRDRPT---------IPAA-----------LSGRG---
Mflv_2131|M.gilvum_PYR-GCK -------------QRV----------------------------------
Mvan_4573|M.vanbaalenii_PYR-1 ----------RSRQHVATG-----------------------NEHG----
MSMEG_5178|M.smegmatis_MC2_155 -------------QPASVG-----------------------MTQSG---
MMAR_4810|M.marinum_M AVGGNSSKFDSNRRVDDH------------------------VHRSPR--
TH_1538|M.thermoresistible__bu DPAPTPXXXDASVRKGPAPSSISRDPAVPAYVPDRP------RTRSACRC
MAB_2275|M.abscessus_ATCC_1997 TAAP---------EPDPVR-------------------------------
MLBr_02620|M.leprae_Br4923 TVSGRPVRPPVTAASLAAPASRVPRGPTHPATLEPSQRARSGLASRPQIK
Mb1177|M.bovis_AF2122/97 --------------------------------------------------
Rv1146|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1287|M.avium_104 QA------------------------------------------------
MUL_0989|M.ulcerans_Agy99 --------------------------------------------------
Mflv_2131|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4573|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5178|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_4810|M.marinum_M --------------------------------------------------
TH_1538|M.thermoresistible__bu SR------------------------------------------------
MAB_2275|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_02620|M.leprae_Br4923 RPQELPSGASTARIQMRPSQSVEATTTRLSVPGNAPTTAAVSSSQGVQAV
Mb1177|M.bovis_AF2122/97 --------------------------------------------------
Rv1146|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1287|M.avium_104 --------------------------------------------------
MUL_0989|M.ulcerans_Agy99 --------------------------------------------------
Mflv_2131|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4573|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5178|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_4810|M.marinum_M --------------------------------------------------
TH_1538|M.thermoresistible__bu --------------------------------------------------
MAB_2275|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_02620|M.leprae_Br4923 PLAATRHPLPTPSPASGQTRAMPVPANRSSDNASETAEPTTALPIMRPQD
Mb1177|M.bovis_AF2122/97 ------------------------------------------
Rv1146|M.tuberculosis_H37Rv ------------------------------------------
MAV_1287|M.avium_104 ------------------------------------------
MUL_0989|M.ulcerans_Agy99 ------------------------------------------
Mflv_2131|M.gilvum_PYR-GCK ------------------------------------------
Mvan_4573|M.vanbaalenii_PYR-1 ------------------------------------------
MSMEG_5178|M.smegmatis_MC2_155 ------------------------------------------
MMAR_4810|M.marinum_M ------------------------------------------
TH_1538|M.thermoresistible__bu ------------------------------------------
MAB_2275|M.abscessus_ATCC_1997 ------------------------------------------
MLBr_02620|M.leprae_Br4923 NDSEVATEKLNALGQGDNSRQHRRATGGGISAQDLLRREGRL