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VSNPAAGKPDHTALRTALWRALHVELDPPPHVLTDLVGLQLAAPEEDWRERPDMDPHGTVDSRLGMVARA RFVEDLVKRRAAEGVGQYVILGAGLDTFVQRHPDAGERLTVFEVDRPETQAWKRKRLTDCGFQIPRWQRL VPVDFEAGACWREQLEIAGFDSGRPAVVASTGVSMYLTRAAIVATLRQCASLATGSTLAMTFLLPDALLN ESARTVRQLIVARAAAAGTPWLSFFAPEEMLSLARECGFAQASYVSGRELIERYVPAAGLSAEEFLVATV
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2253 | - | - | 100% (280) | hypothetical protein MAB_2253 |
| M. abscessus ATCC 19977 | MAB_2209c | - | 2e-24 | 38.35% (206) | hypothetical protein MAB_2209c |
| M. abscessus ATCC 19977 | MAB_3082 | - | 2e-15 | 32.02% (203) | hypothetical protein MAB_3082 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1758c | - | 1e-13 | 30.61% (196) | hypothetical protein Mb1758c |
| M. gilvum PYR-GCK | Mflv_5025 | - | 4e-16 | 35.16% (182) | putative methyltransferase |
| M. tuberculosis H37Rv | Rv1729c | - | 1e-13 | 30.61% (196) | hypothetical protein Rv1729c |
| M. leprae Br4923 | MLBr_02020 | - | 3e-11 | 30.96% (197) | hypothetical protein MLBr_02020 |
| M. marinum M | MMAR_1595 | - | 2e-12 | 31.22% (237) | O-methyltransferase |
| M. avium 104 | MAV_0778 | - | 3e-15 | 34.80% (204) | methyltransferase, putative, family protein |
| M. smegmatis MC2 155 | MSMEG_3424 | - | 2e-34 | 38.35% (279) | transcriptional regulator, MerR family protein |
| M. thermoresistible (build 8) | TH_0301 | - | 7e-11 | 28.99% (238) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_2766 | - | 2e-12 | 36.05% (172) | O-methyltransferase |
| M. vanbaalenii PYR-1 | Mvan_1344 | - | 5e-11 | 30.77% (182) | putative methyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1758c|M.bovis_AF2122/97 ---------MARTDDDNWDLTSSVGVTATIVAVGRALATKDPRGLINDPF
Rv1729c|M.tuberculosis_H37Rv ---------MARTDDDNWDLTSSVGVTATIVAVGRALATKDPRGLINDPF
Mflv_5025|M.gilvum_PYR-GCK ---------MARTPDDSWDLASSVGATATMVAAGRAVASADPDPLINDPY
Mvan_1344|M.vanbaalenii_PYR-1 ---------MARTADDSWDPASSVGATATMVAAGRAAASADPDPLINDPY
MAV_0778|M.avium_104 ---------MARTDHDRWDLATSVGATATMVAAQRALSSDAN--LIDDPY
MUL_2766|M.ulcerans_Agy99 ---------MPRTDNDSWDLATSVGATATMVAAARAIATNADNPLIADRF
TH_0301|M.thermoresistible__bu -----------------------------MXGG----ASRDPKELINDPF
MLBr_02020|M.leprae_Br4923 MMAATPEFGSLRSDDDHWDIVSSVGYTALLVAGWRALHAVGPQPLVRDEY
MMAR_1595|M.marinum_M ---------MSITKNAPREGAEEVAATALGVAAARAAETRRQRPLIVDPF
MAB_2253|M.abscessus_ATCC_1997 --------------MSNPAAGKPDHTALRTALWRALHVELDPPPHVLTDL
MSMEG_3424|M.smegmatis_MC2_155 --------------MDN--SG-PSRTALATAYARACHQFADSPPIFADPL
.
Mb1758c|M.bovis_AF2122/97 AEPLVRAVGLDLFTKMMDGELDMSTIAD--VSPAVAQAMVYGNAVRTKYF
Rv1729c|M.tuberculosis_H37Rv AEPLVRAVGLDLFTKMMDGELDMSTIAD--VSPAVAQAMVYGNAVRTKYF
Mflv_5025|M.gilvum_PYR-GCK AEPLVRAVGLDFFTRMLDGELDLSVFPD--SSPERAQAMIDGMAVRTRFF
Mvan_1344|M.vanbaalenii_PYR-1 AEPLVRAVGLSFFTKMLDGELDLSQFAD--GSPERVQAMIDGMAVRTRFF
MAV_0778|M.avium_104 AAPLVRAVGIDVYVRLVDG-----EIQPG-TSEFDPHRMAKGMACRTRFY
MUL_2766|M.ulcerans_Agy99 AEPLVRAVGVDFFTRWVTGDLVVADVDDT-ESGWQLAQMPDAMAVRARFF
TH_0301|M.thermoresistible__bu AAPLVRAVGIDFFTRIADGELTVADLDP--QSAPRVQANIDEVAVRTRFF
MLBr_02020|M.leprae_Br4923 AKYFITASRDPYLMNLLANP----------GTSLNETAFPRLYGVQTRFF
MMAR_1595|M.marinum_M AQLFVDAAGQDLWSMVASGAAHDELASADPALAAVMQTSLGHIASRTKFF
MAB_2253|M.abscessus_ATCC_1997 VGLQLAAPEE---DWRERPDMDP-------HGTVDSR---LGMVARARFV
MSMEG_3424|M.smegmatis_MC2_155 AARLLGVTEANLDDLSRHPAGHP-------ATVARDRPRRLFFAARSRFA
. : . ::::
Mb1758c|M.bovis_AF2122/97 DDYLLNATAGGIRQVAILASGLDSRAYRLPWP-TRTVVYEIDQPKVMEFK
Rv1729c|M.tuberculosis_H37Rv DDYLLNATAGGIRQVAILASGLDSRAYRLPWP-TRTVVYEIDQPKVMEFK
Mflv_5025|M.gilvum_PYR-GCK DDCCLAAASAGVRQVVILAAGLDARTYRLPWP-DGTVVYELDQPDVIAFK
Mvan_1344|M.vanbaalenii_PYR-1 DDCCGTSTTAGITQVVILASGLDARAYRLGWP-AGTVVYELDQPAVIEFK
MAV_0778|M.avium_104 DDFFLDAARAGVGQAVILASGLDARAYRLPWP-AGTVVYEVDMPDVIEFK
MUL_2766|M.ulcerans_Agy99 DAFFQDATRAGVRQAVILASGLDARAYRLDWP-AGMTVFEIDQPEVIAFK
TH_0301|M.thermoresistible__bu DDHFAAATARGIRQAVILAAGLDARAYRLRWP-DGTVVYEIDQPRVIEFK
MLBr_02020|M.leprae_Br4923 DDFFSSAGDTGIRQAVIVAAGLDSRAYRLKWP-NGATVFEIDLPKVLEFK
MMAR_1595|M.marinum_M DEFVLAAADAGIRQVVSLGAGLDTRAWRLSWP-DAVTVYELEQPNVLEFK
MAB_2253|M.abscessus_ATCC_1997 EDLVKRRAAEGVGQYVILGAGLDTFVQRHPDAGERLTVFEVDRPETQAWK
MSMEG_3424|M.smegmatis_MC2_155 DDVTARAVAAGVRQVVVLGAGLDTAAYRNSHP--DVHVFEVDHPQTQAWK
: *: * . :.:***: . * . *:*:: * . :*
Mb1758c|M.bovis_AF2122/97 TTTLADLGAEPSAIRRAVPIDLRA--DWPTALQAAGFDSAAPTAWLAEGL
Rv1729c|M.tuberculosis_H37Rv TTTLADLGAEPSAIRRAVPIDLRA--DWPTALQAAGFDSAAPTAWLAEGL
Mflv_5025|M.gilvum_PYR-GCK TQTLRNLGAEPAATQRPVPVDLRE--DWPAALRAAGFDATRPTAWLAEGL
Mvan_1344|M.vanbaalenii_PYR-1 TRTLAGLGAHPTATHRPVPIDLRE--DWPAALHAAGFDASRPTAWLAEGL
MAV_0778|M.avium_104 TLTLADLGAQPTAQRRTVAIDLRD--DWAAALREEGFDTQAPAAWSAEGL
MUL_2766|M.ulcerans_Agy99 TTTLAGLGAVPRADLRTVAVDLRQ--DWPKALTEAGFDAGRPTAWIAEGL
TH_0301|M.thermoresistible__bu TRTLARLGAEPTAERRTVAADLRH--DWPAALTAAGFDPAAPTVWIAEGL
MLBr_02020|M.leprae_Br4923 ARVLAEQGAIPNAGRSEVAADLRA--DWPRALKAAGFDPQRSSAWSVEGL
MMAR_1595|M.marinum_M LATLRDNGATPAANYVDVPVDLHR--CWPRSLCLAGFDPAAPTAWLVEGL
MAB_2253|M.abscessus_ATCC_1997 RKRLTDCGFQIPRWQRLVPVDFEAGACWREQLEIAGFDSGRPAVVASTGV
MSMEG_3424|M.smegmatis_MC2_155 RERLAATGIDIPATATLVPVDFET-QTLASELESASFSRTEPAVFVWLGV
* * *. *:. * .*. .:. *:
Mb1758c|M.bovis_AF2122/97 LIYLKPQTQDRLFDNITALSAPGSMVATEFVTGI----ADFSAERARTIS
Rv1729c|M.tuberculosis_H37Rv LIYLKPQTQDRLFDNITALSAPGSMVATEFVTGI----ADFSAERARTIS
Mflv_5025|M.gilvum_PYR-GCK LIYLPPEAQDALFDTVTALSAPGSTLATEYVPGI----VDFDGAKARALS
Mvan_1344|M.vanbaalenii_PYR-1 LIYLPPEAQDQLFDRITALSAPGSTIATEYAPGI----IDFDDEKARAMS
MAV_0778|M.avium_104 LVYLPEQAQDALFDNITALSAPGSRLAFDFVPDT----AVFADPRWRAHH
MUL_2766|M.ulcerans_Agy99 FGYLPPEAQDRLLDNITALSATGSRLACEAIPNRPQQDAEKARELMRKAT
TH_0301|M.thermoresistible__bu FGYLPPDAQDRLLDQITDLSAVGSRLGVEGVPAHADADEDEVRQRMRILA
MLBr_02020|M.leprae_Br4923 LPYLTNDAQSALFTRIGELCAPGSRIAVGALGSR----LDRKQLAALEAT
MMAR_1595|M.marinum_M LPFLSVAAQDLLFGDVHKLSVPGSWLAAEALSSEFLKPTTVARQRARIRR
MAB_2253|M.abscessus_ATCC_1997 SMYLTRAAIVATLRQCASLATG-STLAMTFLLPD-----ALLNESARTVR
MSMEG_3424|M.smegmatis_MC2_155 IFYLTPDAAGSTLDYIAGQARP-VDLVFDYLQP------AETDEDRADLK
:* : : . :
Mb1758c|M.bovis_AF2122/97 NPFRCHGVD--VDLASLVYTGP-RNHVLDYLAAKGWQPEGVS-LAELFRR
Rv1729c|M.tuberculosis_H37Rv NPFRCHGVD--VDLASLVYTGP-RNHVLDYLAAKGWQPEGVS-LAELFRR
Mflv_5025|M.gilvum_PYR-GCK EPLREHGLD--IDMPSLVYTGA-RTPVMDHLRGAGWQVSGTA-RAELFAR
Mvan_1344|M.vanbaalenii_PYR-1 APMREMGLD--IDMPSLVYAGT-RSHVMDYLAGQGWEVTGVP-RRELFTR
MAV_0778|M.avium_104 ERMSELGFE--VDFNDLVYHGE-RSHIVDHLSGRGWRVTSRT-IAELHAA
MUL_2766|M.ulcerans_Agy99 ARWREHGFE--LEFGDLGYEGD-RADVELYLQNLGWQSVGTQ-MSQLLAD
TH_0301|M.thermoresistible__bu ERWRAHGLD--LDFSELIYLGD-RADVAGYLADRGWRCTALT-ANELLVR
MLBr_02020|M.leprae_Br4923 HPGVNISGD--VDFSALTYEP--KTDSAQWLAAHGWAVEPVRNTLELQTS
MMAR_1595|M.marinum_M MRVTAATLAGLSNVTELWDLAEGRSDVADWLRGRGWHASVLT-AERLLAR
MAB_2253|M.abscessus_ATCC_1997 QLIVARAAA--AGTPWLSFFAP--EEMLSLARECGFAQASYVSGRELIER
MSMEG_3424|M.smegmatis_MC2_155 N-RAARLAR--AGEPLVNYLTS--DELHRQLADFGFRVVEDLSGNELIGR
: *: .*
Mb1758c|M.bovis_AF2122/97 SGLDVRAADDDTIFISGCLTDHSSISPPTAAGWR---
Rv1729c|M.tuberculosis_H37Rv SGLDVRAADDDTIFISGCLTDHSSISPPTAAGWR---
Mflv_5025|M.gilvum_PYR-GCK FGRPLPQDADGTDPLG----EIVYVSATLAADA----
Mvan_1344|M.vanbaalenii_PYR-1 YGRPLPPEAGDTDPLG----EIVYVSAHRPQ------
MAV_0778|M.avium_104 NGFA-YAADDVAAAFA----DVTYSSAVLGG------
MUL_2766|M.ulcerans_Agy99 NGAAPIPHNNDSVTMA----DTIYYSSVLTA------
TH_0301|M.thermoresistible__bu TGLPPAENDGR---VT----EVVYLSSEKSPGKRAG-
MLBr_02020|M.leprae_Br4923 YGMTPPDVDVQMDSFM----HSQYITATR--------
MMAR_1595|M.marinum_M YHRSAPVELGDATPPS------LYVTARLSAESSLDA
MAB_2253|M.abscessus_ATCC_1997 YVPAAGLSAEEFLVAT------V--------------
MSMEG_3424|M.smegmatis_MC2_155 YPHGAPVLDERALRAS------RIVHARC--------